Gene reg비 at i o n during the human craniofacial development is not well understood In effort to understand n ewly identifï ed genes that may play role(s) in the human craniofacial development, non-redundan t genes were isolated from the s ubtracted cDNA libra ry of human embryonal craniofacial tissues and examined their possible structu ral rolc in parallcl with thosc gcncs from isolatecl human c h o nclroc)πes cDNA library. Fifty genes were init ia ll y chosen from 398 clones iso latecl were used for selective dominant expression in both chondrocytes and the craniofacial sections of 10 weeks old human embryo by in situ hybridization method. Based upon the high levels 。f expression, we have identifi ecl seven unknown genes; ch89, ch96. ch129. ch 153. ch 276 ch285. and ch334 . In 。rder to unde rs tancl the possi ble role of these genes‘ the structural simulation of the expressed proteins were constructecl by Sybyl 6.6 program. Ch 276 gene was same with a clone, c14 0 1' f173. registered in GenBank(NM_022489) a nd is composed 0 1' 323 amino acids having a reverse s ignaling domain from the extra- cellular matrix(C-terminal) to cell membrane(N-terminal) and 12 turns of helical structure. Gene protein also r etains a famil iar fïbronectin binding domain(RGD). three s ites 0 1' Ca ion binding motifs. cAMP- and cGMP-dep endent protein kinase phos phorylation site, two regions of protein kinase C phosphorylation s ites. glyco- saminoglycan attachment s ite ancl N-glycosylation site. transmembrane and Al kaline Phosphatase active s ite domains This newly iclentifï ed human protein from human choncl rocytes cDNA library appearecl to be related to a known calcification s ignaling protein. was named as Ca lsin(Ch276) . Ch153 appeared to be related a family of anti-microbial peptide acting as an inflammation mediator and Ch334 clone as a zinc finger protein whose expression in creases in human adult ti ssue‘ These results suggest that these novel genes ident i!ï ed from human chondrocytes rnay provide a new path 0 1' embryonic cartilage development and human craniofacial development.

Hemangiomas are different from true vascular malformations in thei l‘ pathogenesis and cl inical prognosis. There are sti ll no standardized antibodies to distinguish hemangioma and vascular malformation apparently. We compared juvenile hemangioma and vascular malformation with immunohistochemjstry using va ri OllS antibodies, i.e. , ANG, bFGF, VEGF. EGFR, vWF. PCNA. p53. maspin, and TNF- . A very st rong positive expression of ANG and vWF was observed mainly in the vascular endothelial cells of juvenile hemangioma. VEGF s howed st rong positive reaction in the juveni le hemangioma, but p53 showed no positive reaction. Ancl a strong positive reaction of ANG was observed in the vascular endothelial walls of vascular malformation. p53 was frequently positive in the lining endothel ial cells in the vascular malformatJOn Using a ntiboclies such as VEG F'. ANG. vWF which a re related to the proliferation and matllrity of the vessel components. and p53 antibodies in order to confirm between juvenile hemangioma and vascular malformation would be helpful

본 연구는 아시아, 유럽, 북미지역에서 두 국가간 자본시장과 금융, 자본재, 소비재, 도 ·소매서비스, 공공산업의 두 국가간 자본시장에서 국제차익거래가격결정 모형(IAPM)의 성립여부와 두 국가간 자본시장 통합여부의 결합가설을 검증하였다. 두 국가간 자본시장의 IAPM 성립여부는 요인분석과 다중회귀분석을 실시하였고, 통합여부는 Chow검증으로 분석하였다. 분석결과, 지역별, 산업별 두 국가간 자본시장이 통합되어있다는 가설을 기각할 수 없는 것으로 나와 지역별, 산업별 두 국가간 자본시장이 통합되어 있다고 밝혀졌다. 이와 같은 연구결과는 지역별, 산업별로 통합된 두 국가 자본시장에서 국제분산투자를 실시함으로써 국내분산투자 보다 더 큰 분산투자효과를 얻을 수 있다는 것을 시사한다.

The effect of biofertilizer (compound of microbial inoculants or groups of micro-organisms) on growth and yield of rice was investigated. The experiment was carried out in a randomized complete block design with 3 replications and 7 treatments namely: RF=N-P2O5-K2O (11-5.5-4.8 kg 10a-1 ); half of the recommended fertilizer rate, HRF=N-P2O5-K2O (5.5-2.75-2.4 kg 10a-1 ); HRF+Bio 250=HRF combined with 250 kg biofertilizer 10a-1 ; HRF+Bio 500=HRF combined with 500 kg biofertilizer 10a-1 ; Bio 250=250 kg biofertilizer 10a-1 ; Bio 500=500 kg biofertilizer 10a-1 ; and NF = No Fertilizer. Results showed that the recorded values of plant height, tiller number and chlorophyll content at 40 to 60 days after transplanting (DAT) in HRF+Bio 500 were significantly higher than those recorded in the RF treatment. Similar observations between these two treatments were only recorded from 60 DAT onwards. Yield components were also superior in HRF+Bio 500 treatment and comparable to that of RF. The highest grain yield obtained in HRF+Bio 500 treatment (785.8 kg 10a-1 ) was statistically similar to that of RF (739.8 kg 10a-1 ) but significantly higher than that of NF (506.7 kg 10a-1 ). Finally, head grain recovery (90.9) was low while chalkiness (0.03) was high at HRF+Bio 500 treatment as compared with RF, which were (96.1) and (0.3), respectively. Results showed that combined treatment of HRF and 500 kg biofertilizer 10a-1 has similar effects on the growth and yield of rice with that of RF.

A new vegetable peanut variety “Bakjung(Arachis hypogaea L.)” was developed from the cross between Shindaekwang and Suwon94 at the Honam Agricultural Research Institute and Yongnam Agricultural Research Institute, National Institute of Crop Science in 200

A new peanut variety “Kokwang(Arachis hypogaea L.)” was developed from the cross between Florigiant and Tifapan at the Honam Agricultural Research Institute in 2003. This variety has shinpung type and erect growth habit with midium size obovate dark green

A new peanut variety “Daemyung(Arachis hypogaea L.)” was developed from the cross between SP8703-2-2 and SP8708-4-1 at the Honam Agricultural Research Institute, National Institute of Crop Sciencee in 2003. This variety belongs to shinpung type with erect

The genetic base was defined as the ancestral pool from which crop varieties were derived, and was used to characterize genetic diversity in crop breeding. Number of primary parents used between 1913 and 2002 in Korean soybean breeding programs was 65 and