이 논문은 구약성서와 유대주의, 그리고 시오니즘(Zionism)에나타나 있는 배타성이 기독교 선교의 공격성과 어떤 연관관계가 있는지를 선교 역사적으로 고찰한 연구이다. 기독교 신앙은 유대교에 뿌리를두고 있는 종교이고, 그 유대교는 타민족에 대한 배타적 선민(選民)사상을 뿌리에 두고 있기 때문에, 이 문제는 기독교 신앙의 정체성뿐만 아니라, 기독교 신앙을 믿지 않는 사람들, 즉 선교 현장의 타자(他者)를 대하는 우리들의 선교적 입장을 결정할 수 있는 중요한 문제이다.더 협소하게 논의를 전개시켜 나간다면, 이것은 선교학과 구약신학간의 대화를 통해서 해소되어야 할 신학적 쟁점이고, 이 논문 역시이러한 목적으로 연례 구약학회에서 발표되었다. 따라서 이 논문은 구약성서의 ‘전사로서의 하나님’에 대한 개념을먼저 살펴보고, 그 결과 나타난 유대주의의 공격성과 배타성을 역사적 으로 규명한다. 이런 전통에서 배출된 예수 그리스도의 ‘군대귀신들린 자’ 사건(막 5:1-20)은 유대주의의 공격성과 배타성을 극복할수 있는 성서학적이며 선교학적인 가능성을 제시하고 있다. 거라사(제라시)에서 군대 귀신들린 자를 축사하신 그리스도는 그를 유대의 땅으로 초청한 것이 아니라 고향 데가볼리로 돌려 보내셨다. 이것을 필자는 유대주의의 배타성과 공격성에서 벗어나 그리스-로마 문명과 공존할 수 있는 선교적 가능성을 제시한 것이라 보았다.이런 개방성으로서의 초대야말로 다원화되고 글로벌화 된 세상을 향한 선교적 복음의 미래라고 해석하였다.

These study was to investigate the in vitro fertilization and viability of fresh and vitrified oocytes. Also, the developmental capacity of IVF and intracytoplasmic sperm injection (ICSI) oocytes were investigated. Then vitrification was performed with the use of 20% ethylene glycol + 20% DMSO + 0.5 M sucrose + 10% FCS + TCM-199 medium. Vitrification immature oocytes are cultured in vitrification solution for 10 min afterwards transferred to expose at room temperature for 5 min. and transferred to the ice water for 5 min. The oocytes were sealed in a 1.0 mm straw and placed in a LN2 container. Frozen oocytes were rapidly thawed in a water bath at 30～35℃, and then placed in TCM-199 medium containing 0.5 M sucrose for 5 min each, respectively, at 38℃. After being washed for 2～3 times, using fresh medium the oocytes were cultured in TCM-199 medium supplemented with 5% FCS at 38℃ in 5% CO2 and air. The normal morphology of fresh and vitrified-thawed oocytes were 87.1±2.1% and 54.8±2.5%, respectively. The viability rates of fresh and vitrified-thawed oocytes were 70.0±2.2% and 41.9±2.6%, respectively. Viability rates of vitrified-thawed oocytes were lower than that of fresh follicular oocytes (p<0.05). The in vitro maturation rates of fresh and vitrified oocytes were 45.1±3.6% and 28.9±4.4%, respectively. The IVF rates of fresh follicular and vitrified-thawed oocytes were 34.0±2.2% and 20.2±2.6%, respectively. The in vitro maturation and fertilization rates of vitrified-thawed oocytes were lower than those of the fresh follicular oocytes (p<0.05). A total of 350 oocytes were fixed and stained after co-incubation with spermatozoa, of which 88 had identifiable nuclear material. After IVF for 20 hrs, 25.1±3.4% of the oocytes found to have been penetrated by spermatozoas. Oocytes were fixed and stained after ICSI, and 105 oocytes contained identifiable nuclear material. After IVF and ICSI for 20 hrs, 34.3±3.4% and 59.0±2.0% of the oocytes were found to have been penetrated by spermatozoas. The developmental rates upon ICSI were significantly higher than those of the IVF method (p<0.05).

The purpose of this study was to investigate the effects of the collection time, co-culture and sperm penetration of canine oocytes on in vitro maturation and fertilization. The oocytes were cultured in TCM-199 media containing hormonal supplements (10% FCS, 10 IU/ml HCG, 10 IU/ml PMSG) at 5% CO2, 95% air, 38℃. The in vitro maturation rate to MⅡ stage of in vitro oocytes recovered from ovaries that collected at follicular, luteal and inactive phases of the reproductive phase for 44～72 hrs were 19.2%, 12.2%, and 6.0%, respectively. Follicular phases oocytes had a significantly higher in vitro maturation rate than oocytes collected at luteal and anestrus stage (p<0.05). The in vitro maturation rates to the MII stage of canine oocytes after 48 hrs of culture with glutathione, pyruvate, or glutathione + pyruvate were 12.5%, 10.7%, and 17.5%, respectively. This was higher than that in both alone or the combination of the two compared to the control group (19.0%). The sperm penetration rates of in vitro matured oocytes by fresh and frozen semen were 29/80 (36.3%) and 18/80 (22.5%), respectively. Although there are limited reports about canine oocytes co-culture and in vitro fertilization, our results on in vitro maturation is comparable to the results from other researches.

Al though the changes in tooth morphology and hardness by hydrogen peroxide(H20 z) have been r‘epor‘.ted .‘ the pαr。o야t뻐ec야tive role of heme oxygenase-l(HO-l) against the cytotoxic effects of H202 has not been clarifïed i n human pulp cells ln this st udy. we investigated whether HO-l is involved in Hz0 2-induced cytoLox icity a nd examined the production 0 1' dentin sia lophosphoprotein(DSPP) and other mineralization markers‘ in hllman pu lp cells H202 decreased cell viabi lity, but increased HO-l and DSPP expression in a concentra tion and time dependent manner . Inhibitors of gllanylate cyclase. PI3K, ERK. and p38 MAP kinase blocked H202-indllced cytotoxicity and the expression of HO-l and DSPP mRNAs in pulp cells. These data suggest that the induction of HO-l by H202 in plllp cells plays a protective role against the cytotoxic effects 0 1' HzOz and stimulates DSPP expression‘ reslllting in prematllre odontoblast dilTerentiation throllgh pathways that involve cGMP‘ p38. and ERK.

Al t hough substance P(SP) , a potent pro- inflammatory peptide, is involved in inflammation and immune responses‘ t he eff'ect of SP on t he expression of macrophage inflammatory protein 3a (MIP- 3α CCL20) in periodontal liga ment(PDL) cell s a re unknown, Equally as enigmatic is the link between SP, t he stress protein heme oxygenase- l(HO-l) ‘ and CCL20 procluction, We investigated whether SP induces the release of chemokine CCL20 from immortal ized PDL(IPDL) ceJJ s‘ and fur ther c l a꺼 SP mediated pathways, We also examined the relationship between HO-l a ncl CCL20 by t reating PDL cells with SP, Incubating IPDL cells with SP increased expression of CCL20 mRNA a nd CCL20 protein in a dose-time dependent manner Highly selective p38 and ERKl/2 inhibitors abrogated SP-induced expression of CCL20 in IPDL cell s, SP is a lso responsible for ini t iating phosphorylation of I/C B, degradation of Iκ B‘ ancl activat ion of NF'-/C B, SP induced expression of HO-l in both a concentration- and time-dependent man nel ‘ and CCL20 refl ected s imilar patterns, The inductive effects o[ SP on HO- l and CCL20 wer e enhanced by HO- j inducer hemin and the membrane-permeable cGMP analog 8-bromo-cGMP, Conversely, this pathway was inJübited by t he 1-10난 inhi bitor zinc protoporphyrin IX(ZnPP IX) and the selective inl뼈itor of guanylate cyc1ase‘ lH-[l , 2, 4Joxad iazole[4‘ 3-aJquinoxal in-l-one (ODQ) , We report herein the pathway that connects SP along with other modulators 。f neuroimmunoregulationto the induction of HO-l and t he inflammatory mediator MIP-3a /CCL20 in IPDL cell s‘ which play an important role in the development 01' periodontitis or inflamrnation during orthodontic tooth movem

The characteristics of meteorological conditions relevant to Asian dust (AD) outbreaks and their occurrence frequencies were analyzed in four source regions (R1 to R4) during spring months (March to May) of 1998-2002. Moreover, the concentration variations of AD (e.g., PM10) observed in Korea were investigated during the study period. In the relationship between AD outbreaks and three meteorological parameters (i.e., air temperature, wind speed, and aridity), the largest AD outbreaks in April (～250 observations) mostly occurred in R2 when air temperature ranging from 10.0 to 15.0℃ and surface wind speed from 7 to 9 m s-1 were recorded. Moreover, the aridity (≥ 4) in April was significantly high in R2 with the maximum frequency of AD outbreaks (i.e., 206 observations). On the other hand, the number (percentage) of days belonging to AD events observed in five Korean cities were found to be 116 (44%), 121 (46%), and 26 days (10%) in March, April, and May, respectively. The mean PM10 concentrations were found to range from 150 to 220, 150 to 200, and 95 to 120 ㎍ m-3 in March, April, and May, respectively. Consequently, this implied that the AD events in Korea were found to be gradually frequent in early spring and to be affected from the large AD outbreaks observed in the source regions.