In this study, antibody responses after vaccination against equine influenza were investigated among 1,591 horses in the Republic of Korea using the hemagglutination inhibition (HI) test. Equine influenza has not occurred since 2011 and a commercial vaccine against H3N8 has been used. The equine influenza virus, A/equine/South Africa/4/03 (H3N8), was used as the antigen in the HI assay. The mean seropositive rate was 90.5% in 2019. Except for stallion whose seropositive rate was 78.5%, all seropositive rates of other horse types were over 90%. Regionally, except for Gangwon-do and Jeju-do whose seropositive rates were 89.0% and 87.1%, all seropositive rates in other provinces were over 90%. In the future, more through vaccination against equine influenza needs to be done based on this investigation result.

Graphene, a carbon crystal sheet of molecular thickness, shows diverse and exceptional properties ranging from electrical and thermal conductivities, to optical and mechanical qualities. Thus, its potential applications include not only physicochemical materials but also extends to biological uses. Here, we review recent experimental studies about graphene for such bioapplications. As a prerequisite to the search to determine the potential of graphene for bioapplications, the essential qualities of graphene that support biocompatibility, were briefly summarized. Then, direct examples of tissue regeneration and tissue engineering utilizing graphenes, were discussed, including uses for cell scaffolds, cell modulating interfaces, drug delivery, and neural interfaces.

본 연구는 바이오기업의 외부 네트워크 전략을 공동연구 협력, 제조/마케팅/판매 제휴, 자금지원, M&A 등 4가지로 구분하고, 이와 같은 바이오기업의 외부 네트워크 전략이 기업의 성과에 미친 영향을 살펴보기 위하여 미국 바이오기업 패널자료를 사용하여 분석한다. 첫째, 기술개발 이후의 제조/판매/마케팅 제휴는 단기간에도 모든 기업성과를 증진시키는 역할을 하였다. 둘째, 기술개발단계에서의 연구개발협력 중 제약회사와의 협력은 1~2년 이후의 기업성과에, 그리고 타 바이오기업과의 연구개발협력은 2년 이후의 기업성과에 정의 효과를 가져왔다. 셋째, 가장 장기적이며 기초연구에 주목적을 두고 있는 공공기관 및 대학과의 공동연구 협력은 단기적인 기업성과에 부정적으로 작용하여, 향후 2~3년이 아닌 보다 장기적인 관점에서 재조명되어야 하는 것으로 나타났다. 이러한 실증분석 결과는 국내 바이오산업의 발전을 위하여 외부 네트워크 전략을 통하여 기술혁신을 경주하는 노력이 필요하며, 또한 주로 기초기술에 집중된 공공기관과 대학과의 공동연구를 지원하는 정책적 고려가 필요함을 시사한다.

The genetic diversity was evaluated using RAPD and ISSR among natural populations and Korean wheat cultivars (Triticum aestivum). Understanding the genetic diversity of putative parental and wild stocks would be useful in wheat breeding programs. Ninety three populations were evaluated with fifty RAPD and three ISSR primers. A total of 185 RAPD and ISSR polymorphism were produced. These markers were considered to estimate the genetic distance among accessions. The genetic similarity ranged from 0.41 to 0.86. The dendrogram were constructed by using the UPGMA clustering algorithm based on genetic similarity. The genetic diversity within and among accession was assessed through Principal Component Analysis (PCA) for statistics analysis. In cluster analysis, four groups were clustered and 17 accessions were not clustered. The PCA was corresponded well to the result. This study provides basic information about the genetic relationships for breeding purposes.