Many manufacturers applying third party logistics (3PLs) have some challenges to increase their logistics efficiency. This study introduces an effort to estimate the weight of the delivery trucks provided by 3PL providers, which allows the manufacturer to package and load products in trailers in advance to reduce delivery time. The accuracy of the weigh estimation is more important due to the total weight regulation. This study uses not only the data from the company but also many general prediction variables such as weather, oil prices and population of destinations. In addition, operational statistics variables are developed to indicate the availabilities of the trucks in a specific weight category for each 3PL provider. The prediction model using XGBoost regressor and permutation feature importance method provides highly acceptable performance with MAPE of 2.785% and shows the effectiveness of the developed operational statistics variables.
목적 :본 연구는 급성기 뇌졸중 환자에서 로봇 보조 상지 훈련의 효과를 알아보고자 실시하였다.연구방법 :2015년 6월 1일부터 2015년 8월 30일까지 전북 익산 소재의 W 대학병원에 입원한 급성기 뇌졸중 환자 14명을 실험군과 대조군으로 무작위 할당하였다. 두 군 모두 전통적인 작업치료를 실시하였다. 추가적으 로 실험군에는 로봇 보조 상지 훈련을 대조군은 전통적 작업치료를 각 1일 1회 30분, 주 5회, 총 4주간 실시하였 다. 치료 중재 전·후 상지기능을 측정하기 위해 Fugl-Meyer 평가척도(Fugl-Meyer Assessment-Upper Extremity; FMA-UE), 상지 기능 검사(Manual Function Test; MFT)을 사용하였고 일상생활활동 수행능 력을 평가하기 위해 한국판 수정된 바델 지수(Korean version of Modified Barthel Index; K-MBI)을 사용하였고 장악력을 평가하기 위해 Jamar dynamometer을 사용하였다.결과 :4주 치료 후 두 그룹 모두에서 중재 전·후 상지 기능, 일상생활활동 수행능력, 장악력에서 유의한 차이가 나타났으며(p<.05) 중재 후 두 그룹 간 변화량의 차이에서는 모두 유의한 차이가 나타나지 않았 다(p>.05).결론 :본 연구 결과 로봇 보조 상지 훈련이 급성기 뇌줄중 환자의 상지 기능, 일상생활활동 수행력, 장악력 을 향상 시킬 수 있는 중재 방법으로 나타났다. 그러므로 로봇 보조 상지 훈련은 뇌졸중 환자의 상지 재 활에 초기부터 안정적이고 신뢰적인 장비로 표준화된 치료를 지원할 수 있는 중재 방법으로 사용될 수 있을 것이다.
This study was performed to identify the state of the exposure and characteristics of pollutants by each process at 4 casting sites located in Gyeongsang-do from April to November 2013. The concentrations of methanol, crystallized silica glass, formaldehyde and phenol were analyzed by different process - casting process, molding process, core process, and shakeout & finishing process. The highest concentration of methanol was found in casting and molding process, whereas the highest concentration of crystalline quartz(Silica) was observed in core process. The most oxidized steel dusts and the highest concentration of fume were found in shakeout & finishing process. As a result of this study, those labors working at the casting site were found to be constantly exposed to various forms of hazardous chemicals; therefore, it is considered that this is the time to manage and plan how to reduce them. In addition, it is required to thoroughly manage the local exhauster, and improve the process and working environment to reduce various forms of hazardous chemicals.
강황 분말을 0, 2, 3, 4%를 첨가한 어묵을 제조하여 색도, 절곡검사, 조직감, 관능검사 등의 품질 특성을 조사하였다. 색도 변화는 L, a값은 강황 분말의 첨가량이 증가할수록 감소하였고 b값은 증가하였다. 어묵의 유연성과 탄력성을 나타내는 절곡검사에서는 대조군을 포함한 모든 시료에서 AA로 측정되어 강황 분말의 첨가에 관계없이 우수한 것으 로 나타났다. 강황 분말을 첨가한 어묵의 기계적 texture 특성은 강황 분말 첨가량이 증가할수록 경도(hardness), 응 집성(cohesiveness), 탄력성(springiness)은 증가하였고, 검 성(gimminess)과 파쇄성(brittleness)은 감소하였다. 관능검 사 결과로 색깔(color), 향미(flavor), 조직감(texture), 맛 (taste), 전체적인 선호도(overall acceptance)는 3%의 첨가군 이 가장 높은 평가를 받았다. 따라서 강황 분말을 첨가한 기능성 강황 어묵의 가공 적성에 적절한 강황의 첨가량은 3%가 적당하다고 사료되며 강황을 함유한 고품질 어묵의 제조 가능성을 확인하였다.
Amylopectin composition is determined by the relative activity of soluble starch synthase (SSS) and granule-bound starch synthase (GBSS). Soluble starch synthase and starch branching enzymes are major determinants for the synthesis of amylopectin while GBSS1 is responsible for amylose synthesis in vivo. The formers are made of linear and branched molecules and the latter is composed of highly branched molecules. To increase the palatability of rice, down-regulation of amylose synthesis by antisense and RNA interference (RNAi) could be excellent and powerful tools for controlling the starch composition which is responsible for grain eating quality. The goal of this study is to generate breeding lines with lower amylose content relative to its wild type. This study also reports the results of the two down-regulating technology in lowering the amylose content of rice grain. Furthermore, this study elucidates the effect of using antisense and RNAi for SSS1 and GBSS1.
Rice is one of the most important major food crops which provide the major food for more than half of global population. To improve the grain quality as well as grain yield has been the essential breeding goal in rice. The composition of amylopectin is the determinant of rice eating quality under certain threshold of protein content and the ratio of amylose and amylopectin. In this study, RBE 1 driven by CaMV-35S promoter was constructed and transformed using Agrobacterium tumefaciens. We selected single copy with low amylose content among transgenic lines. The mRNA expression was investigated using RT-PCR, and enzyme activity was determined using activity staining method in mid-milky stage endosperm. Also, the overexpression vectors for RBE 1 and SSS 1 driven by seed specific globulin promoter were constructed, respectively. Moreover, the RNA interference vectors for soluble starch synthase 1 and granule bound starch synthase 1 derived by CaMV35S promoter were constructed, respectively and transformed using Agrobacterium tumefaciens. The transgene has been confirmed by amplification of HPT and target gene. The transgenic plants obtained will be used to investigate the gene function of related starch pathway in plant cells using Gopumbyeo as a wild type rice, based on the gain-of-function and the loss-of-function. The development of designed site-specific endonucleases boosted the establishment of gene targeting (GT) techniques in a row of different species. However, the methods described in plants require a highly efficient transformation and regeneration procedure and, therefore, can be applied to very few species. Here, we describe a highly efficient GT system that is suitable for all transformable plants regardless of transformation efficiency. Efficient in planta GT was achieved in rice by expression of a site specific endonuclease (SSS1::ZFN) that not only cuts within the target but also the chromosomal transgenic donor, leading to an excised targeting vector.