The purpose of the study was to evaluation of the radiation dose reduction using various automatic exposure control (AEC) systems in different manufactures multi-detector computed tomography (MDCT). We used three different manufacturers for the study: General Electric Healthcare, Philips Medical systems and Siemens Medical Solutions. The general scanning protocol was created for the each examination with the same scanning parameters as many as possible. In the various AEC systems, the evaluation of reduced-dose was evaluated by comparing to fixed mAs with using body phantom. Finally, when we applied to AEC for three manufacturers, the radiation dose reduction decreased each 35.3% in the GE, 58.2% in the Philips, and 48.6% in the Siemens. This applies to variety of the AEC systems which will be very useful to reduce the dose and to maintain the high quality.