이 연구의 목적은 우즈베키스탄으로 귀환한 비전문취업노동자의 질병 과 사고의 경험, 의료기관의 이용, 안전 및 건강의 관리 실태를 살펴보 고, 연구결과를 바탕으로 국내 이주노동자의 건강 증진과 보건의료 서비 스의 향상을 위한 정책적 시사점을 도출하는데 있다. 연구대상은 국내에 서 노동을 하고 우즈베키스탄으로 귀환한 비전문취업노동자 15명이며, 현지를 방문하여 인터뷰조사를 통해 자료를 수집·분석했다. 주요 연구 결 과는 첫째, 우즈베키스탄 귀환 이주노동자의 질병과 사고는 대부분 근골 격계와 호흡기계 분야에서 발생했다. 둘째, 국내 의료기관 이용은 전반적 으로 만족도가 높았고, 의사와 간호사의 충분하고 친절한 설명과 진료에 대해 만족했다. 셋째, 우즈베키스탄 귀환 이주노동자의 안전관리는 회사 내에서 안전 교육이 비교적 잘 이루어지고 있었다. 넷째, 우즈베키스탄 귀환 이주노동자의 건강 관리는 한국인과 유사하게 종합영양제를 복용하 거나 비정기적이지만 산책, 낚시, 헬스, 축구 등을 통해 이루어졌다. 마 지막으로, 국내 이주노동자의 전반적인 건강실태 파악을 위해 연구대상 자의 확대와 양적연구방법을 활용한 후속연구를 진행할 필요가 있다.
본 연구는 담배거세미나방 국내 개체군의 예찰에 필요한 성유인제의 최적 조성을 찾기 위해 수행하였다. 담배거세미나방 암컷 성충에서 알 려진 두 성페로몬 성분인 (Z,E)-9,11-tetradecadienyl acetate, (Z,E)-9,12-tetradecadienyl acetate를 5.5 ~ 10.0 및 9:1 ~ 99.1, 9:1 ~ 39:1 비 율 사이에 여러 조성으로 만들어 고무격막 방출제에 담아 펀넬트랩을 이용하여 콩과 땅콩포장에서 수컷 성충에 대한 유인력을 비교한 결과, 두 성 분의 19:1 비율이 가장 적절한 유인 조성으로 결정하였다. 그러나 Z9E11-14:Ac 단독 성분 미끼에는 수컷 성충이 거의 유인되지 않았다. 이 결과 는 담배거세미나방 성충 예찰용의 성유인제 구성에는 두 성페로몬 화합물이 반드시 필요한 성분임을 나타낸다. 미끼에 담긴 성페로몬은 0.1 ~10 mg 사이에서 함량이 증가할수록 유인된 수가 많았다. 적절한 트랩 설치 높이는 1.5 m로 결정하였다.
This study is analyse method for Industrial disester prevention of E-9 foreign workers. To do this, We adapted tp TRIZ 's creative problem solving theory and AHP, QFD. TRIZ is determined some parameters for problem solving and selected the inventive principles for each parameters. So, We made new parameters and inventive principles under theory of the TRIZ process for reduced to the foreign worker’s disaster rate. After, The derived parameters and the inventive principles are used to evaluate the importance of factors through the AHP, and determine the weight of the relation through QFD expansion. Finally. this paper applies statistical data according to the determined model process, analyzes the result and proposes improvement method for the prevention of disaster of foreign workers
Pleomorphic adenoma (PA) is the most common benign salivary gland tumor. It is biphasic and is characterized by an admixture of epithelial and spindle-shaped myoepithelial cells in a variable background stroma. Epithelial-myoepithelial carcinoma (EMC) is a malignant biphasic salivary gland tumor typically composed of clear myoepithelial cells that surround epithelial-lined ducts resembling intercalated ducts. The differential diagnosis between the two tumor may be occasionally encountered because of the shared histophatologic feature. And then, it would be more reliable to differentiate the tumors based on biological behavior such as the expression of distinct intermediate filaments such as cytokeratin, invasiveness- related molecules, and the growth factor receptor to aberrantly facilitate the tumor growth, and the growth fraction of tumors. Therefore, from the 10 cases of PA and 6 cases of EMC, we immunohistochemically examined the differential expression of the cytokine 7 and 14, matrix metalloproteinase-9, C-KIT, and Ki-67 between the two tumor. At the results, there were significant differences of CK7 expression in non-luminal cells (P = 0.000) and CK14 expression in luminal and non-luminal cells of the both tumors (P = 0.025 and P = 0.000, respectively). In the comparison of the biologic behavior, a significantly increased expression of MMP-9, C-KIT and Ki-67 was found in the cases of EMC when compared to those of PA (P = 0.043, P = 0.011, and P = 0.000, respectively). In conclusion, the differences of CK expression in luminal and non-luminal cells between PA and EMC seem to reflect the difference of the origin and the level of the maturation of the tumor cell. Increased expression of MMP-9, C-KIT, and Ki-67 in EMC may represent more aggressive biologic behavior of the tumor compared with benign salivary tumor such as PA. Our results may be helpful to understand the histiogenesis of the two tumors and the difference of biologic behavior and to differentiate them when the limited specimen was submitted. Further study of many more cases of EMC is needed to validate the usefulness of these molecules as the diagnostic aid.
Matrix metalloproteinases(MMPs) are involved in the degradation of extracellular matrix, which is re lated to infiltrative growth and metastasis of tumor and are regulated by tisslle inhibitor of metalloproteinases(TIMPs) or cell adhesion molecllles such as E-cadherin and epidermal growth factor receptor (EGFR). The aim of this study is to evaluate the relationship between MMP-2, MMP-9 expressions and clinico-pathologic factors, 끼MP-1 , TIMP-2, EGFR and E-cadherin expressions. lmmunohistochemical stains were perfom1ed on 55 cases of squamous cell carcinoma of the ordl cavity and the results were as follows. MMP-2 and MMP-9 expressions were noted in 30(54.5%) and 22(40.0%) of 55 cases, TIMP-1 and πMP-2 in 21(38.2%) and 33(60.0%), and E-cadherin and EGFR expressions in 35(63.6%) and 26(47.3%) of 55 cases, respectively. MMP-2 expression rdte was slightly higher 띠 cases without recurrence, and 끼MP- 2 expression rate was slightly higher in cases showing more inftltrative growth pattem. 까1e expression rate of EGFR was higher in cases with well differentiation(p=0.OO47), but no posi디ve relationship between the expression rate of Ecadherin and histologic grade was found. Cases with positive reaction for MMP-9 showed an increasing tendency of nega디ve reaction for TIMP-1. π1e expression rate of MMP-2 was higher in cases with positive reaction for E-cadherin and EGFR with no statistical significance. 까1e expression rate of MMP-9 was significantly higher in cases with positive reaction for E-cadherin(p=0.022l). These results suggest that MMP-2, MMP-9, TIMP-1 and TIMP-2 expressions are involved in the development of oral squamous cell carcinomas, but MMP-2, MMP-9, 끼MP-1 , and 끼MP-2 expressions might not seem to be a useful prognostic factors because there were no significant relationship between clinicopathologic parameters. EGFR expression showed positive correlation with low histologic grade, so EGFR expression could be regarded as a good prognostic factor. In the progression of sqllamous cell