Angiolymphoid hyperplasia with eosinophilia (ALHE) is a vascular inflammatory disease characterized by painless mass in the dermis, subcutaneous tissue, or both in the head and neck region. However, occurrence in the oral mucosa is extremely rare. In this study, we report a case of ALHE that occurred on the upper lip and discuss the histopathological features and management.

Eosinophilic gastroenteritis (EGE) is a rare inflammatory disorder that predominantly affects the stomach and the small intestine, although its pathogenesis is not yet known precisely. EGE shows distinct peripheral eosinophilia and eosinophilic infiltration of the intestinal wall. A 12-month-old girl who was breastfeeding presented with bilateral eyelid swelling without gastrointestinal symptom. Laboratory examination showed peripheral eosinophilia and hypoalbuminemia and iron deficiency anemia. Gastric and duodenal biopsy specimens revealed eosinophilic infiltration of the mucosal layer. We experienced a case of eosinophilic gastroenteritis without any gastrointestinal symptom, associated with maternal food contained allergen.

Ankylosing spondylitis (AS) is an inflammatory joint disease affecting the axial skeleton, peripheral joints, entheses, and extra-articular site. Non-steroidal anti-inflammatory agents are the first line drugs for treatment of AS. Sulfasalazine is regarded as the second line drug and is usually used on AS patients with concomitant peripheral arthritis. Sulfasalazine has side effects, including liver toxicity, hematological abnormality, skin eruption, and other symptoms. However, eosinophilic pleural effusion is rare. Thus, we report on a patient with peripheral eosinophilia and eosinophilic pleural effusion after taking sulfasalazine for treatment of AS.