Veterinary medicines have been widely used for disease protection, growth promotion, and feed efficacy development of animals. Along with development of livestock and pet industry, veterinary medicine market in Korea has increased up to 1 billion US dollar in 2021. The national post-market surveillance (NMS) assessment is important system to manage quality control of veterinary medicines that have reached the open market in Korea. In this study, post marketed veterinary medicines have been analyzed particularly for the active ingredient contents based on the rule, “Tips on animal pharmaceutical audit” and monitored the noncomplicant compounds for prevention of adverse drug event. 6,620 veterinray medicines were chosen by NVRQS-SE10-V1 software program which we developed annually in Korea during 2018-2021. The programe chooses veterinary medicines which is 70% were selected products with high sales in order, 20% were selected products with low sales randomly and 10% were noncompliant product from last year automatically, as we input year`s sales and noncompliant product data. The Animal and Plant Quarantine Agency (APQA) leads collection of veterinary medicines from manufacturing companies, drug stores, and hospitals. The NMS assay was analyzed particularly for the active ingredient ingredients performed using liquid and gas chromatography, titration, UV/Vis spectrophometer, pH, and bioassay in Korea Animal Health Production Association (KAHPA). A total of 129 cases were deemed noncompliant and the average noncompliance rate for veterinray medicines was 1.9%. Among noncompliant products violating regulations, the leading cause was insufficient quantity of major ingredients. The compounds found to be noncompliant most frequently were tylosin, spiramycin, ampicillin, amoxicillin and colistin, respectively In this study, we analyzed the results of post marketing surveillance assay from 2018 to 2021 particularly violation rate and pattern. The overall trend indicated gradually decreasing noncompliance rate from 2.7% to 1.6%, suggesting that the quality of veterinary medicines has improved according to the steadily NMS assay and settlement of Korea Veterinary Good Manufacturing Practice (KVGMP) system.

HNS 사고 후 활용할 수 있는 모니터링 지침 개발을 위해 국내외 HNS 사고 후 해양환경영향평가 및 모니터링 관련 사례를 검토하였다. 그 첫 단계로 해양생물 및 서식처를 중심으로 하는 HNS 사고 후 모니터링 및 해양환경영향평가 지침을 개발하였고, 의사결정자 및 작업실무자들에게 적합하도록 내용을 구성하였다.

이 논문에서는 벽체의 형상(평면벽체, 곡면벽체) 및 벽체에 도입된 긴장력이 충돌저항성능에 미치는 영향을 수치해석적 기법을 사용하여 평가하고자 하였다. 벽체의 곡률 및 긴장력 도입률을 변수로 총 12 케이스의 충돌해석을 수행하였으며, 충돌체로는 상용 민항기엔진의 3차원 상세모델을 사용하였다. 충돌저항성능을 평가하기 위해 관입깊이와 벽체 중앙부 후면의 최대 변위를 비교하였다. 긴장력의 도입에 의해 관입깊이는 약 60∼80% 수준으로 감소하는 것으로 나타났으나, 후면 변위는 큰 차이가 나타나지 않았으며, 벽체 형상에 따른 차이는 상대적으로 크지 않은 것으로 나타났다.

This study carried out passenger safety assessment by real car crash simulation of composite post structures for road facilities. The effects of different material properties of composites for various parameters are studied using the LS-DYNA finite element program for this study. In this study, the existing finite element analysis of steel post structures using the LS-DYNA program is further extended to study dynamic behaviors of the structures made of various composite materials. The numerical results for various parameters are verified by comparing different models with displacements and stress distribution occurred in the post and car.