Effects of horticultural therapy program for various client groups have been announced, but in order to specialize and include these effects in the health care community, it needed more obvious effects and researches about specific area connected with horticultural therapy among whole medical care such as effects and economic value for practical use. Especially it may be useful that reliable clinical data and cost-effectiveness which is compared it with other treatments are presented. This research accomplished as pilot study which present cost-effectiveness analysis model according to problems and clinical indicator which can act with horticultural therapy for activating public relation and introduction of horticultural therapy of practical use. This study concerned very necessary trial to inform the effect of horticultural therapy program widely to the health care community especially. In the future, continuous studies and efforts for economic value of horticultural therapy should be needed.

This thesis had an aim to help university students act floriculture effectively, and investigated universities' preference of the flower color objectfying 149 students. The three cut flowers in our country were selected, and they are the rose, the carnation, and the chrysanthemum. This thesis inquired of thirty flower gardens about color selection through telephone, and selected the most favored colors of three cut flowers asking the customers. The colors were red, yellow, and pink. This thesis established six polling booths in the lecture room 6.3m wide and 7m long, and put the rose, the carnation, and the chrysanthemum. To investigate the preference of color based on cut flower put in the polling booth 1,2, and 3, this thesis put the common color - red, pink, and yellow to investigate the preference of cut flower based on color in the polling booth 4,5,6. Scrutinizing the flower color after experimental study based on cut flower, this thesis found out that in the case of the rose, the most objects(48 persons, p=0.064) of investigation preferred yellow. In the case of chrysanthemum, the most objects(107 persons, p=0.0000) preferred pink. The rose and the chrysanthemum were significant statistically. Scrutinizing the preference of the cut flower based on the color, in the case of red cut flower, the most objects(89 persons, p=0.0000) preferred the rose, and in the case of yellow cut flower, the most objects(52 persons, p=0.0000) preferred the rose. In the case of pink cut flower, the most objects(89 persons, p=0.003) preferred chrysanthemum. All of them were significant statistically. When scrutinizing the tendency based on sex and age, this thesis found out that in the case of flower color, the persons 19～22 years old preferred pink carnation, and the persons 23～29 years old preferred yellow carnation. All of them were significant statistically(0.007) But the tendency based on sex or age were not significant statistically.

Acyl-CoA synthetase 4는 생쥐에 있어서 거의 모든 조직에서 발현하며 아라키돈산에 특이적인 효소이다. 아라키돈산은 세포막의 인지질로부터 cPLA2에 의하여 유리되고 cyclooxygenase-1, -2에 의하여 eicosanoid로 변환된다. 이렇게 생산된 prostaglandin과 같은 eicosanoid는 배란, 수정, 임신에 있어서 중요한 기능을 수행하고 있다. 그러나 세포막으로부터 유리된 아라키돈산은 acyl-CoA syntheta

Inositol은 세포의증식 및 정보전달과정에 관여하는 phosphatidylinositol (PI)의 구성성분으로서 중요한 세포내 기능을 수행한다. P1는 세포내에서 특이적 인산화효소에 의하여 Pl4-phosphate(PIP), Pl4,5-phosphate()로 변환되며 PIP는 phospholipase C(PLC)에 의하여 세포내 second messengers인 1,2-diacylglycerol (DAG)와 inositol 1,4,5-triphos

To find the mechanism underlying the ADP-induced increase in the outward current in ovulated mouse oocytes, we examined changes in voltage-dependent currents using the whole cell voltage clamp technique and the internal perfusion technique. Eggs were collected from the oviduct of superovulated mice with PMSG and hCG. Membrane potential was held at -60 mV (or -80 mV in the case of recording currents) and step depolarizations or hyperpolarizations were applied for 300 ms. By step depolarizations, outward currents comprising steady-state and time-dependent components were elicited. They were generated in response to the positive potential more than 20 mV with severe outward rectification and were blocked by external TEA, a specific channel blocker, suggesting that they be carried via channels. Internally-perused 5 mM ADP gradually increased outward currents (IK) 1 min after perfusion of ADP and reached slowly to maximum (150~170％) 5 min later over the positive potential range, implying that ADP might not be acted directly to the channels. IK were decreased by 5 mM ATP without affecting the steady-state component of outward current. In contrast to the effect of ADP and ATP on IK, both effect of ATP and ADP on inward currents (ICa) could not be detected due to the continuous decrease in current amplitudes with time-lapse ("run-down" phenomena). To check if there is a G protein-involved regulation in the ionic current of mouse oocytes, 1 mM GTP was applied to the cytoplasmic side, and the outward current and inward currents were recorded. ICa was promptly increased in the presence of GTP whereas IK was not changed. from these results, it is concluded that the ATP-dependent regulation is likely linked in the ADP-induced increase in the outward current, and G protein-involved cellular signalling might affect ion channels carrying and in mouse oocytes.