The use of animals heavily impacts the mental health of researchers performing the animal experiments. The animal researchers need to take care of animals but also give pain and sacrifice them at the same time. This circumstance can cause a variety of mental stress to the researchers. The stress generated in the laboratory would not only negatively affect the management of animals and the research results, but also would harm the researchers’ physical and mental health. Because the feeling of sympathy for animals is a natural feature of humanity, psychological stress following a laboratory animal’s death after use is not surprising. It is necessary to revise the relevant laws based on understanding the difficulties of animal researchers in society and to develop related educational programs at the national level to help the psychology and emotions of researchers who conduct animal experiments.

Recently, the Defense Advanced Research Projects Agency(DARPA) in the United States is studying a new concept of war called Mosaic Warfare, and MUM-T(Manned-Unmanned Teaming) through the division of missions between expensive manned and inexpensive unmanned aircraft is at the center. This study began with the aim of deriving the priority of autonomous functions according to the role of unmanned aerial vehicles in the present and present collaboration that is emerging along with the concept of mosaic warfare. The autonomous function of unmanned aerial vehicles between the presence and absence collaboration may vary in priority depending on the tactical operation of unmanned aerial vehicles, such as air-to-air, air-to-ground, and surveillance and reconnaissance. In this paper, ACE (Air Combat Evaluation), Skyborg, and Longshot, which are recently studied by DARPA, derive the priority of autonomous functions according to air-to-air collaboration, and use AHP analysis. The results of this study are meaningful in that it is possible to recognize the priorities of autonomous functions necessary for unmanned aircraft in order to develop unmanned aerial vehicles according to the priority of autonomous functions and to construct a roadmap for technology implementation. Furthermore, it is believed that the mass production and utilization of unmanned air vehicles will increase if one unmanned air vehicle platform with only essential functions necessary for air-to-air, air-to-air, and surveillance is developed and autonomous functions are expanded in the form of modules according to the tactical operation concept.

Long-term non-surgical contraceptive methods for cats, especially community cats, are of global interest for cost-effective and humane reasons. This study aimed to investigate the effectiveness of a gonadotropin-releasing hormone (GnRH)-based vaccine for immunocontraception and to confirm its safety in intact female cats. Recombinant Salmonella typhimurium flagellin fljB (STF2)-GnRH protein was expressed in Escherichia coli. We divided female cats into vehicle control group (n = 4) and two experimental groups (100 μg injection group [n = 7] and 1000 μg injection group [n=7]), and immunized them twice intramuscularly (0.2 mL/cat at zero week and 4 weeks later into the other leg). Breeding trials started on day 120. All control cats (n = 4/4), 71% of the 100 μg injection group (n = 5/7), and 57% of the 1000 μg injection group (n = 4/7) became pregnant within 203 days after the introduction of male cats. The 1000 μg injection group had significantly a longer median time to conception following treatment (166 days) than the control (17 days, p < 0.05). Average litter size was significantly lower in the 1000 μg GnRH-vaccinated cats (2.8 ± 0.7) than in the control cats (4.5 ± 0.5, p < 0.05). Injection site reactions were not observed in any cat. The E. coli-expressed STF2-GnRH vaccine did not provide contraception in a sufficient proportion of the cats. However, it might be effective to suppress fertility through infertility vaccines before inducing permanent infertility through the trap-neuter-return.

Mercury and its compounds are globally managed chemicals as risks to the human body and ecosystem. It mainly enters the human body through ingestion of seafood, especially, methylmercury causes serious diseases such as central nervous system (CNS) disorder and renal dysfunction. In this study, total mercury (Hg) and methyl mercury (MeHg) were determined in seafood (16 species, n = 97) commonly consumed in Daejeon, using a gold amalgamation method. The average concentration (Hg/MeHg mean ± S.D. (minimum–maximun) mg/kg) of total Hg and MeHg in the samples was as follows; Fish 0.038 ± 0.058 (0.004 – 0.272) / 0.028 ± 0.047 (N.D. – 0.236), Crustacea 0.023 ± 0.021 (0.003 – 0.078) / 0.016 ± 0.018 (N.D. – 0.055), Mollusks 0.015 ± 0.015 (0.002 – 0.056) / 0.008 ± 0.013 (N.D. – 0.040). The concentration of MeHg in seafood were significantly correlated with total Hg concentration (p<0.001). The species with the highest average concentration of Hg was the Korean rockfish, but there was no sample that exceeded the maximum residual limit. The total %provisional tolerable weekly intake (%PTWI) value of MeHg for all of the samples was 3.76%, compared with the JECFA’s reference value, which indicates that there is almost no health risk from heavy MeHg intake through the consumption of seafood distributed in Daejeon.

바위솔국(Delosperma cooperi)은 레소토(Lesotho)와 남아 프리카 공화국(Republic of South Africa)에 자생하는 다년생 초본성 다육식물의 일종으로 옥상녹화의 재료 및 생체모방 자가복구 소재(biomimetic self-repairing material)의 연구재 료로써 사용되어지고 있다. 뿐만 아니라 지피식물 혹은 실내 관상용 식물로 원예로써도 가치가 있을 것으로 전망된다. 본 연구에서는 바위솔국 재배에 최적화 된 환경을 알아내기 위해 온실의 차광수준[50, 65, 80, 95%, (Under-Bed, 98%)], 분용 토(각각 마사토, 펄라이트, 강모래, 유비상토, 버미큘라이트 가 배합된 토양) 및 시비량[(control, 0ppm), 500, 750, 1,000, 2,000ppm]의 처리로 나누어 실험을 진행하였다. 결과적으로 바위솔국은 50% 차광수준에서 가장 우수한 생육 수준을 나타 냈으며 분용토 실험에서는 유비상토, 버미큘라이트와 펄라이 트가 적절히 혼합된 VL:FM:PL(3:2:5, v/v/v)에서 생육이 가장 우수하게 나타났다. 시비량 실험에서는 1000ppm 수준에서 양 호한 생육을 나타내었다. 바위솔국의 엽색은 65% 이하의 차 광수준에서 짙은 녹색(RHS N137A, 147A)으로 나타났고 80% 이상의 차광수준에서는 엽색이 황색(RHS 146A, 147B, 148A) 으로 평가되었다. 차광수준 실험에서 잎의 CIELAB L*과 b* 값 과 식물체의 생육 간에 상관관계를 분석하였는데 이들은 서로 음의 상관관계를 나타내는 것으로 나타냈으며 일조량이 부족 할수록 잎이 황화 되어 생육이 불량해지는 것과 관계가 있는 것으로 나타났다. 반면에 시비량에 대한 실험에서는 생육과 엽색간 상관관계는 없는 것으로 나타났다.

The PoN (Proof of Nonce) distributed consensus algorithm basically uses a non-competitive consensus method that can guarantee an equal opportunity for all nodes to participate in the block generation process, and this method was expected to resolve the first trilemma of the blockchain, called the decentralization problem. However, the decentralization performance of the PoN distributed consensus algorithm can be greatly affected by the network transaction transmission delay characteristics of the nodes composing the block chain system. In particular, in the consensus process, differences in network node performance may significantly affect the composition of the congress and committee on a first-come, first-served basis. Therefore, in this paper, we presented a problem by analyzing the decentralization performance of the PoN distributed consensus algorithm, and suggested a fairness control algorithm using a learning-based probabilistic acceptance rule to improve it. In addition, we verified the superiority of the proposed algorithm by conducting a numerical experiment, while considering the block chain systems composed of various heterogeneous characteristic systems with different network transmission delay.

This study attempted to reinterpret the meaning of the Roh MooHyun Jeju-Declaration in accordance with the age of artificial intelligence based on the liberal theory. In the era of artificial intelligence, a new aspect of the U.S.-China hegemonic competition was considered. The Roh MooHyun Declaration, which declared Jeju Island a peaceful island, was reinterpreted from three points of view of liberal theory. This study presented the necessity and orientation of the World Peace Island Network International Organization.

This study aims to restore the dignity of the elderly based on “filial piety” and community values in preparation for the 'silver tsunami' in Jeju by studying the case of Whitney Center in the United States, PASSi, Jeju's Isidol Nursing Home, and the haenyeo society. The main goal was to develop the Asian Jeong Nang model which was named by professor Koh Chang Hoon, Chair of Island Research Institute at Jeju National university. Jeong Nang(정낭) is the gateway with 3 wooden bars to the traditional residential space of Jeju where several generations live together. Dr. Hesung Chun Koh, Chair of East Rock Institute gave me motivation and support for the study of the elderly welfare model at the Jeju National University Island Research Institute. As the head of this study, I was dispatched from the Jeju National University Island Research Institute to the East Rock Institute (ERI). Dr. Hesung Chun Koh, M.D. Ann Datunashivili who is a practice professor at Medical School of Yale and in charge of Medical Center of Whitney Center. and Mike RambaRose who is Chief Executive Officer of Whitney Center, supported my research. In addition ImJa Choi, CEO of PASSi, also allowed two research students, Lee Seung Yong and Ko Yu Seok, from Jeju National University, to help my research related to psycho-social approach for the elderly at PASSi. This study was intended to develop a model for senior citizens in Korea through Hesung Chun Koh's ERI CCAI Model, Whitney Center's residential apartment model for retired seniors, and PASSi's community care model for the multi-cultural community.

The purpose of this study is to introduce a non-fungible token(NFT) for the protection of Gotjawal, and to propose a virtuous cycle of re-donation to a donation organization for the main goal and protection through the auction process. The Gotjawal Trust of Jeju is active in Jeju Island. It started with a problem consciousness to link the NFT to the movement of the Gotjawal Gong Yoo Fire Foundation. It proposed requirements for successful application of NFT to Gotjawal sharing. First, there is a need for a convincing story about why the Gotjawal Shared Fire Foundation entered the NFT market. Second, it is necessary to examine whether there is a reputation of the Gotjawal Gong Yoo Fire Foundation that can be solved by NFT. Third, it is important to develop and promote logic that can guarantee the "future value will continue or increase" of the Gotjawal Shared Foundation NFT. The effects of applying NFT to the protection of Gotjawal are as follows. Securing the reliability of the Gotjawal Foundation Movement, adding the concept of investment to donations, continuing activation of donations through a virtuous cycle structure, connecting donations to ownership, and digitalizing donation certificates to secure objectivity of certification.

Since the Korean pronoun system does not specify gender indication, Korean speakers of English tend to have difficulties when they use English pronouns. This paper explores how absence of obligatory gender marking in Korean affects gender errors in the production of English. Gender pronoun errors made by Korean learners of English were analyzed using recordings of English conversations of seven Korean subjects. Findings of this study revealed that Korean English learners struggled with the use of gender pronouns due to differences in gender pronoun systems between Korean and English. Both gender-neutrality and pro-drop practices do not require Korean speakers to pay close attention to gender factors when using pronouns in their native language, resulting in native language interference. Considering that the Korean language lacks specific gender orientation in its usage of pronouns whereas English requires clear gender specification, findings of this study imply that native language gender concept can influence second language use.

최근 살진균제는 세계 식량 안보에 없어서는 안될 필수 요소이며, 그 사용량은 증가하고 있다. 살진균제는 직접적 또는 간접적으로 곤충에 영 향을 미쳐 유전자 및 분자 수준의 변화를 일으킨다. 곤충은 다양한 해독 매커니즘을 통해 살진균제를 포함한 농약으로부터 유발되는 활성산소 (ROS) 독성을 제거한다. 본 연구는 살진균제 캡탄의 비치명적 투여량(0.2, 2, and 20 μg/μL)을 주입 후 갈색거저리의 유충에서 해독효소의 mRNA 발현량을 분석했다. 갈색거저리의 전사체 분석을 통해 해독 매커니즘 관련 유전자인 퍼옥시다제(POX), 카탈라제(CAT), 슈퍼옥사이드 디스뮤타제(SOD) 및 글루타티온-S-트랜스퍼라제(GST)를 발굴하였다. 처리 24시간 후 TmPOX5 mRNA가 유의하게 증가한 것으로 나타났다. 처리 3 시간 후 TmSOD4의 mRNA가 유사하게 증가하였다. 또한 2 μg/μL 처리 24시간 후 TmCAT2의 mRNA 가 유의하게 증가하였다. 캡탄 노출 후 TmGST1 및 TmGST3의 mRNA 발현량도 증가하였다. 결론적으로, TmPOX5 및 TmSOD4 유전자는 갈색거저리에서 캡탄 노출에 대한 바이오마커 또는 생체이물 센서로 작용할 수 있음을 시사한다.

The poor durability issue of polymer electrolyte membrane fuel cells is a major concern in terms of their commercialization. To understand the degradation mechanism of the catalysts, an accelerated durability test (ADT) was conducted according to the protocol established by internationally accredited organizations. However, reversible and irreversible factors contributing to the loss of activity have not yet been practically segregated because of the limitations of a batch-type three-electrode system, leading to the misunderstanding of the deactivation mechanism. In this study, we investigated the effect of a fresh electrolyte on the ADT and recovery process. When the fresh electrolyte was used at every range of the cycle, the chances of incorrect detection of dissolved CO and Pt ions in the electrolyte were very low. When the same electrolyte was used throughout the test, the accumulated Pt ions were deposited on the surface of the Pt nanoparticles or carbon support, affording an increased electrochemical surface area (ECSA) of Pt. Therefore, we believe that periodic replacement by a fresh electrolyte or a continuous-flow electrolyte is essential for the precise determination of the structural and electrochemical changes in Pt/C catalysts.

Despite having a low electrical conductivity, graphene oxide (GO) is used as an anode material in lithium-ion batteries (LIBs) owing its good processability in large quantities. GO is reduced by chemical or thermal treatments to enhance its electrical conductivity. In this study, high-performance GO anodes with polydopamine (PDA) and polyethylenimine (PEI) as binders were fabricated. Gamma (γ)-ray irradiation was applied to the GO–PDA–PEI hybrid sheets to covalently cross-link the GO sheets and binders with an amide bond. The covalent crosslinking was confirmed by Fourier-transform infrared spectroscopy analysis. Further, X-ray photoelectron spectroscopy results showed that γ-ray irradiation produced a reduced GO sheet, which resulted in an increase in the electrical conductivity by 30%. By characterizing the electrochemical properties, we found that the γ-ray irradiation facilitates the stability and increases the charge/discharge capacity by crosslinking GO and PDA–PEI binders and reducing the GO sheets.

We have prepared MIL-101/graphene oxide (GO) composites with various mixing molar ratio of Fe-containing metal– organic frameworks (MOFs) against GO. When synthesizing MOFs, it was possible to synthesize uniform crystal powders using hydrothermal method. MIL-101 consists of a terephthalic acid (TPA) ligand, with the central metal composed of Fe, which was the working electrode material for supercapacitors. Field emission scanning electron microscopy, X-ray diffraction, Fourier transform infrared spectroscopy, and X-ray photoelectron spectroscopy analysis had been done to ascertain microstructures and morphologies of the composites. Cyclic voltammetry, electrochemical impedance spectroscopy, and galvanostatic charge–discharge measurements were performed to analyze the electrochemical properties of the composite electrodes in 6 M KOH electrolyte. By controlling the metal ligand mole ratio against GO, we prepared a changed MOF structure and a different composite morphology, which could be studied as one of the promising optimized electrode materials for supercapacitors.

Sugarcane bagasse has been used as a substrate for the development of microporous nano-activated carbons for the treatment and elimination of dissolved materials from aquatic environment. The activated carbon was produced using chemical activation in one-step method with zinc chloride ( ZnCl2) as the activating agent at a carbonization temperatures range from 500 to 900 °C. The effects of temperature and time of carbonization on the activated carbon product properties were thoroughly studied. The activated carbons that resulted were characterized using the N2 adsorption/desorption isotherms, Brunauer–Emmett–Teller method (BET), pore property analysis, micropore (MP) surface area, t-plot surface area, TGA, FTIR, SEM, TEM, and EDX analyses. The prepared activated carbon’s point of zero charge, Boehm titration process, iodine removal percentage, and methylene blue number were also investigated. The prepared activated carbon’s maximum surface area was achieved using a 2/1 impregnation ratio (dried sugarcane bagasse/ZnCl2) at 600 °C temperature of carbonization and 60 min residence time. 1402.2 m2/ g, 0.6214 and 1.41 cm3/ g, respectively, were the largest surface area, total pore volume, and micropore volume. As the activation temperature increased, the total pore volume increased and the BET study measured a pore diameter of 0.7 nm and a mean pore diameter of 1.77 nm.

Traditional tie-dyeing is widely implemented in the clothing handicraft culture in China, South Korea, and Japan. Since it was developed 2,000 years ago, it has become a popular method of fabric making in the world and is highly respected by fashion designers. Based on the existing traditional tie-dyeing methods, this study conducted specific research on the 3D printing technology of the SLS laser method and the micro tool design application method of the clamp-dyeing process. Through the experimental methods of this study, it proposes to use the “7000 Nylon” material, which is commonly used in 3D printing, to develop a new clamp-dyeing tool. This new tool can be widely used in the clamp-dyeing of fabrics, such as cotton, hemp, silk, and some chemical fibers. The applied method and principle can be consistent with the traditional clamp-dyeing method. Therefore, the innovation of tie-dyeing technology is the best protection measure for the development and inheritance of traditional fabric making. The continuation of artistic life needs originality, which is also the best response to market competition. At the same time, this new design of the clamp-dyeing tool has the characteristics of novelty, innovation, and rich changes, which aligns with the new fashion demands of current fabric design.

The production of macroalgae-derived adsorbent is of great importance to realize the idea of treating pollutants with invaluable renewable materials. Herein, a novel meso-micro porous nano-activated carbon was prepared from green alga Ulava lactuca in a facile way via chemical activation with zinc chloride. The resultant activated carbon possesses a significant specific surface area 1486.3 m2/ g. The resulting activated carbon was characterized and investigated for the adsorption of Direct Red 23 (DR23) dye from an aqueous environment. Batch method was conducted to study the effects of different adsorption processes on the DR23 dye adsorption from water. Isotherms and kinetics models were investigated for the adsorption process of DR23 dye. It was found that the adsorption data were well fitted by Langmuir model showing a monolayer adsorption capacity 149.26 mg/g. Kinetic experiments revealed that the adsorptions of DR23 dye can be described with pseudo-secondorder model showing a good correlation (R2 > 0.997). The prepared activated carbon from Ulava lactuca was exposed to a total of six regeneration experiments. The regeneration result proved that the fabricated activated carbon only loses 19% of its adsorption capacity after six cycles. These results clearly demonstrated the high ability of the obtained active carbon to absorb anionic dyes from the aqueous environment.

To improve the pyrolytic carbon (PyC) deposition rate of Carbon/Carbon (C/C) composites prepared by the traditional chemical vapor infiltration (CVI) method, the 3D Ni/wood-carbon (3D Ni/C) catalyst was introduced into the CVI process. The effects of catalyst on the density of C/C composites were studied, and the deposition rate and morphologies of PyC were investigated after catalytic CVI. The morphologies of catalyst and PyC were characterized by scanning electron microscope and polarized light microscopy. The catalytic deposition mechanism of PyC was studied by density functional theory. The experimental results show that the initial carbon deposition efficiency of the catalytic pyrolysis process was 3–4 times that of the noncatalytic process. The catalyst reduced the energy barrier in the first step of deposition reaction from 382.55 to 171.67 kJ/mol according to simulation results. The pyrolysis reaction energy with Ni catalyst is reduced by 54% than that without the catalyst.

Herein a rich, Se-nanoparticle modified Mo-W18O49 nanocomposite as efficient hydrogen evolution reaction catalyst is reported via hydrothermal synthesized process. In this work, Na2SeSO3 solution and selenium powder are used as Se precursor material. The structure and composition of the nanocomposites are characterized by X-ray diffraction (XRD), high-resolution field emission scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS), EDX spectrum analysis and the corresponding element mapping. The improved electrochemical properties are studied by current density, and EIS analysis. The as-prepared Se modified Mo-W18O49 synthesized via Na2SeSO3 is investigated by FE-SEM analysis and found to exhibit spherical particles combined with nanosheets. This special morphology effectively improves the charge separation and transfer efficiency, resulting in enhanced photoelectric behavior compared with that of pure Mo-W18O49. The nanomaterial obtained via Na2SeSO3 solution demonstrates a high HER activity and low overpotential of -0.34 V, allowing it to deliver a current density of 10 mA cm2.

The mercury ion ( Hg2+) is regarded as one of the toxic cations that is extremely harmful and dangerous to human health and the environment. With this growing awareness, it is imperative that facile and rapid sensing systems developed for the detection of Hg2+. Due to excellent sensitivity and selectivity, graphene quantum dots (GQDs), a zero-dimensional carbon nanomaterial, are attracting the attention of researchers as promising candidates as fluorescent probes for Hg2+ detection. This study aimed at conducting an in-depth review of recent advances into GQD-based materials as fluorescent probes in Hg2+ sensing. This systematic review was carried out by covering three main databases, namely, Scopus and Science Direct as the dominant databases, followed by Google Scholar as the supporting database. GQD-based materials encompassing bare GQDs, N-GQDs, B, N-GQDs, N, S-GQDs, N, K-GQDs, RhB-GQDs, Cys-GQDs, PEHA-GQD-DPA, Gly-GQDs, Mn(II)-NGQDs, NH2– Ru@ SiO2- NGQDs and FA-GQDs were discussed thoroughly with regard to their synthesis strategies, along with their potential application in the detection of Hg2+. The doping of heteroatoms is envisaged to enhance the quantum yield and selectivity of bare GQDs. This review might unlock a wide range of opportunities for the application of various GQD-based materials as an adaptable, feasible and scalable approach to the detection of Hg2+.