Crohn’s disease is a chronic inflammatory bowel disease, involving gastrointestinal tract and extra-intestinal organs. IgA nephropathy is a rare extra-intestinal manifestation of Crohn’s disease. We describe a case of 21-year old Korean man who was diagnosed with Crohn’s disease 5 years after IgA nephropathy was suspected. At the age of 16, he had gross hematuria and 2 years after he was diagnosed with IgA nephropathy. Three years later, he complained of abdominal pain and diarrhea. He was diagnosed with Crohn’s disease by colonoscopy and histologic exams. There has been increasing evidences of common pathophysiology between the two diseases.

Toxocariasis is an illness of humans caused by roundworm. Toxocara species are commonly found in dogs and cats. Humans are accidental hosts. There are two routes of infection. One route is the ingestion of infected eggs, and the other route is the ingestion of an infected paratenic host. Clinical manifestations vary from asymptomatic infection to severe organ failure. In most cases, the patients are asymptomatic and the disease is self-limited. Thus, patients with mild symptoms do not require treatment. However we report on cases of patients with asymptomatic hepatic nodules who were treated to exclude malig-nant disease.

The association of colorectal cancer with ulcerative colitis (UC) is well-recognized. However, not much is known regarding the increased risk of extra-intestinal malignancies with UC. Several studies have revealed that patients with UC are at in-creased risk of hepatobiliary cancer, nonmelanoma skin cancer, and myeloid leukemia. A 41-year-old man was diagnosed with UC in 1993 and had three relapses over the next three years. Six months after the fourth remission, he developed pan-cytopenia and was diagnosed with acute promyelocytic leukemia (APL). He achieved complete remissions of APL through chemotherapies, and, since then, no recurrences of APL and UC were observed.