Helicobacter pylori are known as a causative agent of gastritis, gastric duodenum and peptic ulcer, and gastric cancer, and multiple drug use is associated with various side effects in patients. The discovery of antibacterial substances against H. pylori from Korean resource plants is an important substitute for antibiotics. 52 species of Korean resource plants were collected and extracted with 50% ethanol, and antibacterial activity against H. pylori was measured using the disk diffusion method. The toxicity of plant extracts to human gastric adenocarcinoma(AGS) cells was measured by MTT assay, and the level of IL-8 secreted when gastric epithelial cells were inoculated with H. pylori was measured. As a result of measuring the antibacterial activity of H. pylori, antibacterial activity was confirmed in 38 plant extracts. The plant species with the strongest antibacterial activity were Chrysanthemum indicum, Rheum rhabarbarum, Patrinia scabiosaefolia and Petasites japonicus. C. indicum was not cytotoxic to H. pyroli-infected AGS cells and showed anti-inflammatory effects. This study's results can be used to develop healthy, functional foods and medical materials.

본 연구는 민간시장의 절화 유통 현황을 조사하여 국내 절 화 시장 유통 및 판매의 기초 자료로 제공하고자 수행하였다. 조사 기간은 2022년 5월부터 10월까지이며, 민간시장 내 판 매 점포 수, 취급 품목, 수입국 및 품목 등을 비교 및 분석하 였다. 민간시장은 서울 서초구 반포동에 위치한 강남터미널 꽃시장을 대상으로 판매 품목 및 수입 국가 등을 조사하였고, 비교 대상인 공영시장의 경우 한국농수산식품유통공사 화훼 유통정보에서 제공되는 양재동 화훼공판장 거래 품목을 조사 하였다. 조사 결과, 민간시장의 월별 절화 판매 점포 수는 평 균 143개였다. 민간시장에서는 5월을 제외하고 장미 판매 매 장이 가장 많았다. 5월에는 카네이션 판매 매장이 가장 많았 으며 장미, 리시안셔스, 거베라가 그 뒤를 이었다. 민간시장 점포 내 수입 품목의 원산지는 호주, 중국, 콜롬비아, 이스라 엘, 이탈리아, 일본, 네덜란드, 페루, 남아프리카 공화국, 미 국, 베트남 등으로 조사되었다. 취급 품목은 민간시장이 69개 로 공영시장 18개에 비해 약 3.8배 많았으며, 이는 민간시장에서 수입 절화가 더 많이 유통되고 있음을 시사한다. 민간시 장은 공영시장과 달리 유통 정보를 알 수 있는 시스템이 없어 소비자들이 제품의 원산지, 품질, 가격 등을 파악하기 어렵다. 따라서, 민간시장의 절화 유통 정보를 소비자들에게 정확히 제공할 필요가 있으며, 이를 통한 투명한 거래 제공 및 소비자 의 신뢰도를 높이는 것이 중요하다.

The chemical composition of 86 species of native plants in Korea, including plants to be afforestation, was analyzed. The chemical composition of the species analyzed was different. The species with the highest extractable content was Viburnum dilatatum (3.91%), and the species with the lowest extractable content was Ligustrum lucidum (0.11%). The lignin content ranged from 12 to 39%, with an average of 25%. The species with the highest lignin content was Chaenomeles lagenaria (39.37%). Hemicellulose content ranged from 18 to 52%, with the highest species being Thuja occidentalis (51.22%) and Eucommia ulmoides (48.84%). Cellulose content ranged from 25 to 58%, and the species with the highest content were Prunus serrulata (57.67%), Diospyros kaki (57.14%), Aesculus turbinata (53.29%), Albizia julibrissin (53.02%), and Zelkova serrata (52.29%). The chemical composition was different for each use taxon of 86 plant species. The lignin content was the highest in the fruit group and the lowest in the group other than recommended species for afforestation. Cellulose content was highest in non-reforestation-recommended tree species and lowest in fruit trees. In classification according to tree height, lignin content was higher in shrubs than in tall trees, and cellulose content was highest in tall trees. Between deciduous and evergreen trees, the lignin content was high in deciduous trees (26.46%), and the cellulose content was also high in deciduous trees (44.01%). As a result of analyzing the correlation between each compound, there was a difference. There tended to be a positive correlation between extractives and lignin content. There was a negative correlation between extractives and holocellulose content, hemicellulose and cellulose. The higher extract content affected the cellulose content much more than hemicellulose. Also, the higher the lignin content, the lower the cellulose content. The species with low lignin content and high cellulose content were Diospyros kaki and Prunus serrulata var. spontanea. This result is expected to be primary data for bioenergy, pulp industry and bioindustry.

The objective of this study is to investigate the safety awareness and effectiveness of the education and training for employees engaged in radiological emergency organization of the Korea Atomic Energy Research Institute (KAERI). In 2022, the questionnaire for the education satisfaction survey was revised to regulary evaluate the effect of edcation on perceptions of importance on emergency preparedness for nuclear research facilities. In line with, a standard questionnaire was created which covers 3 factors and 9 attributes, and the evaluation indicatior is based on a 5-point Likert scale. In 2023, the education on radiological emergency preparedness was conducted for 235 emergency staff. From May 24 to July 13, 2023, data was collected from a total of 235 emergency response personnels, including 28 new staffs and 207 maintenance staffs. Aa a result of response analysis, it was identified that education for radiological emergency response had a significant correlation with the promoting safety culture. It was found that senior emergency personnel with more years of experience are highly interested in radioactive disaster prevention and actively participate in and training. On the other hand, it was presented that new and less experienced groups tend to have a relatively high scored of the risk perception of nuclear research facilitites. Therefore, it is necessary to improve the practical curriculum in order to increase the participation of junior disaster prevention personnel in education and training, ensuring that they correctly recognize the risk of research facilities. This results are expected to be used to improve the quality of education and drills for radiological emergency response at KAERI.

North Korea continues to upgrade and display its long-range rocket launchers to emphasize its military strength. Recently Republic of Korea kicked off the development of anti-artillery interception system similar to Israel’s “Iron Dome”, designed to protect against North Korea’s arsenal of long-range rockets. The system may not work smoothly without the function assigning interceptors to incoming various-caliber artillery rockets. We view the assignment task as a dynamic weapon target assignment (DWTA) problem. DWTA is a multistage decision process in which decision in a stage affects decision processes and its results in the subsequent stages. We represent the DWTA problem as a Markov decision process (MDP). Distance from Seoul to North Korea’s multiple rocket launchers positioned near the border, limits the processing time of the model solver within only a few second. It is impossible to compute the exact optimal solution within the allowed time interval due to the curse of dimensionality inherently in MDP model of practical DWTA problem. We apply two reinforcement-based algorithms to get the approximate solution of the MDP model within the time limit. To check the quality of the approximate solution, we adopt Shoot-Shoot-Look(SSL) policy as a baseline. Simulation results showed that both algorithms provide better solution than the solution from the baseline strategy.

기후 변화의 가속화로 국내 제주 및 남부 지방을 중심으로 열대 및 아열대 작물의 재배 및 소비가 증가하는 추세이다.오크라는 식용적 가치가 있을 뿐만 아니라, 품종별 고유의 꼬 투리와 잎의 색은 관상적 가치가 있어 조경 식물로 많이 사용 되고 있다. 본 연구는 도심 내 옥상 온실에 관상식물인 오크 라를 도입하기 위해 피트모스와 펄라이트 비율에 따른 기초 종자 발아 및 육묘기 실험을 진행하였다. 피트모스와 펄라이 트 비율은 PT:PL=1:2, 1:1, 2:1, 4:1 네 가지로 조성하였다. 발 아율은 파종 후 7일차부터 다른 처리구에 비해 피트모스:펄라 이트=1:2의 처리구에서 가장 높았다. 파종 후 28일차와 70일 차에 줄기길이, 경경, 뿌리길이, 지상부와 지하부의 생체중과 건물중 그리고 엽면적은 피트모스:펄라이트=1:2 처리구에서 가장 높았다. 그러나, 파종 후 56일 이후부터 엽수는 피트모 스:펄라이트=1:2, 2:1, 4:1 처리구에서 감소하였다. 피트모스: 펄라이트=1:1, 2:1, 4:1 처리구에서 식물이 필요로 하는 피트 모스의 비율이 지나치게 높아 높은 피트모스 비율로 인하여 수분함수량이 과도하게 높아 식물이 고사한 것으로 판단된다. 따라서 오크라를 관상식물로 활용하기 위해서는 피트모스와 펄라이트를 1:2로 혼합한 배지가 가장 적합하다.

Resistance to extended-spectrum cephalosporin in Enterobacteriaceae is increasingly prevalent in South Korea. This study aims to explore the distribution of AmpC genes in Proteus mirabilis isolated from stray and hospital-admitted companion animals in South Korea. AmpC β-lactamases hold clinical significance due to its potential to facilitate antimicrobial resistance to cefoxitin, cefazolin, and most penicillins. A total of 163 bacterial isolates belonging to the Enterobacteriaceae family were collected from dogs (n = 158) and cats (n=5). Of them, 134 isolates were from hospital-admitted animals, while 29 isolates from stray animals. Boronic acid tests and antimicrobial susceptibility tests were conducted for an initial screening to detect AmpC β-lactamase resistant P. mirabilis. Gene-specific PCRs were conducted to identify the type of AmpC genes, which include six groups (MOXM, CITM, DHAM, ACCM, EBCM, and FOXM), in the resistant isolates. The boronic acid disk tests revealed 45 (27.6%) positive isolates out of 163 isolates tested. Of these 45 isolates, six were determined to harbor the EBCM gene, 13 for CITM, one for FOXM, and one for DHAM by single detection PCR. No isolates carried for ACCM or MOXM. Thus, a total of 21 out of 163 isolates (12.9%) were demonstrated to possess AmpC genes. No isolates contain more than one group of AmpC gene family. A significantly higher percentage of P. mirabilis was found to possess AmpC genes compared to past studies. Therefore, the increasing trend in antimicrobial resistance in P. mirabilis indicates a dire need to monitor antimicrobial prescription in the veterinary field.

본 연구는 스프레이 타입의 절화 장미가 재배되고 있는 호 남지역 스마트팜의 시설과 연중 재배환경을 분석하고, 그에 따른 외적 특성과 수명을 분석하고자 수행하였다. 본 연구에 서 선정한 스마트팜은 연동형 유리 온실로 CCTV를 통해 실시 간으로 농가 상황이 확인 가능하며, 1세대 스마트팜으로 조사 되었다. 스마트팜 시설 내 재배환경은 여름에 최고온도가 다 른 계절에 비해 높았고, 겨울에는 일적산광량이 최소 광요구 도에 미치지 못하는 것으로 나타났다. 또한, 상대습도는 겨울 과 가을에 유의적으로 높아 겨울의 VPD는 0.3kPa로 낮게 조 사되었다. 양액의 pH는 계절에 따라 차이가 없었으나 EC는 봄과 여름에 적정 범위를 벗어난 것으로 나타났다. 외적 특성 과 절화수명은 스마트팜 내에서 많이 재배되고 있는 ‘Egg Tart’, ‘Flash Dance’, ‘Pink Yoyo’, ‘Super Sensation’ 품종을 조 사하였다. 외적 특성 분석 결과, 대부분의 품종이 다른 계절에 비해 겨울에 절화장이 길었으나 줄기가 얇았고 소화수가 적었 다. 여름에는 꽃의 크기가 작았으며 화색이 퇴색되어 명도인 L값이 다소 높고, a값과 b값이 낮아 다른 계절보다 선명하지 않은 것으로 조사되었다. 절화수명 조사 결과, ‘Egg Tart’ 품종 은 계절별 차이가 없었으나 ‘Flash Dance’, ‘Pink Yoyo’, ‘Super Sensation’ 품종은 가을에 가장 길었으며 세 품종 모두 겨울, 여름 순으로 절화수명이 다소 짧은 것으로 조사되었다. 이는 여름의 고온과 겨울의 일적산광량 부족 및 과습한 환경이 꽃 의 크기와 화색발현, 절화수명 감소에 부정적인 영향을 미치 는 것으로 판단된다. 따라서, 고품질의 절화 장미가 생산 될 수 있도록 이에 적합한 스마트팜 환경 제어 시스템 개발과 현 장 적용을 통한 개선이 필요하며, 현재, 본 연구의 스마트팜에 서는 지상부 복합 환경 제어가 가능하기 때문에 축적한 자료 들을 이용한 빅데이터 분석 및 의사 결정 지원시스템이 갖춰 진다면, 2세대 스마트팜으로 발전 가능성이 높을 것으로 판단 된다.

Royal jelly (RJ) is a gelatinous substance that bees produce to feed bees and queen bees. It’s frequently sold as a dietary supplement to treat a variety of physical ailments and chronic diseases. While it has long been used in traditional medicine, its applications in Western medicine remain controversial. The inhibitory effect of royal jelly on osteoarthritis was investigated in primary cultured rat cartilage cells and monosodium-iodoacetate (MIA)-induced arthritis rat model 10-hydroxy-2-decenoic acid (10-HAD) is the main fatty acid present in RJ. Among the criteria for RJ quality analysis, 10-HAD content has been proposed as a freshness parameter. We investigated the effect of RJ on the improvement of osteoarthritis on SD rats and they were divided into five groups. In this study, we examined the effect of enzymatic royal jelly (ERJ) administration on osteoarthritis. To determine the antiinflammatory effects of RJ, tumor necrosis factor alpha (TNF-α) and Interleukin-6 (IL-6) expression were measured after lipopolysaccharide (LPS) activation in RAW 264.7 cells. In in vivo animal study, osteoarthritis was induced by intra-articular injection of MIA into knee joints of rats. As a results, ERJ showed that TNF-α and IL-6 levels were decreased by ERJ treatment in a dosedependent manner. In conclusion, ERJ extract was able to inhibit articular cartilage degeneration by preventing extracellular matrix degradation and cartilage cell damage. It was considered that ERJ extract may be a potential therapeutic treatment for degenerative osteoarthritis.