This paper presents an electrochemical immunosensor using a graphene/multi-walled carbon nanotube (MWCNT) composite platform for detecting the cardiovascular marker C-reactive protein (CRP). The immunosensor exhibited a linear detection range of 0.20–100 ng/mL CRP with a low limit of detection reaching 0.081 ng/mL. The composite material provided a 3D porous structure that allowed efficient antibody immobilization and minimized steric hindrance. The sensor showed high specificity, with minimal response to interfering substances. Using differential pulse voltammetry, the immunosensor demonstrated exceptional precision, rapid detection, and a direct correlation between CRP concentration and sensor response current. Overall, this work highlights the potential of the graphene/MWCNT composite platform as a robust tool for early CRP detection and cardiovascular disease risk assessment. The immunosensor provides sensitive and selective CRP quantification that could enable timely clinical intervention for at-risk individuals.

For solving phase separation of nanoparticles and graphene oxide (GO) in the application process, MgWO4– GO nanocomposites were successfully synthesized using three different dispersants via a facile solvothermal-assisted in situ synthesis method. The structure and morphology of the prepared samples were characterized by X-ray diffraction, Scanning electron microscopy, Transmission electron microscopy, Fourier transform infrared and Raman techniques. The experimental results show that MgWO4 nanoparticles are tightly anchored on the surfaces of GO sheets and the agglomeration of MgWO4 nanoparticles is significantly weakened. Additionally, MgWO4– GO nanocomposites are more stable than self-assembly MgWO4/ GO, which there is no separation of MgWO4 nanoparticles and GO sheets by ultrasound after 10 min. The catalytic results show that, compared with bare MgWO4, MgWO4– GO nanocomposites present better catalytic activities on the thermal decomposition of cyclotetramethylenete tranitramine (HMX), cyclotrimethylene trinitramine (RDX) and ammonium perchlorate (AP). The enhanced catalytic activity is mainly attributed to the synergistic effect of MgWO4 nanoparticles and GO. MgWO4– GO prepared using urea as the dispersant has the smallest diameter and possesses the best catalytic action among the three MgWO4– GO nanocomposites, which make the decomposition temperature of HMX, RDX and AP reduce by 10.71, 11.09 and 66.6 °C, respectively, and the apparent activation energy of RDX decrease by 68.6 kJ mol−1.

Although there are many international treaties and conventions offering protection for generic human rights that implicitly refer to older persons, these relevant provisions are scattered, porous and lack of practical operability, which fail to provide explicit, tailored, comprehensive and binding protection to older persons. In addition, there are some soft law provisions that guide the application of law and add to the overall protection of older people. However none of the documents contains legally binding obligations. Therefore, the protection of the rights of the elderly must be formulated as the “hard law” which defines the responsibilities of the state and clarifies the implementation mechanism at the international and domestic level. In other words, a legal system ought to be established to comprehensively protect the rights of the elderly, which is just the Convention on the Rights of the Elderly. This article attempts to present a proposal to create the right system of the Convention, which represents the core of this potential international treaty.

The recent fentanyl dispute between China and the US adds the academic value to the efforts to examine the respective legal regime of public international law and the WTO law on narcotics trafficking. On the one hand, public international law offers a comprehensive framework to address narcotics trafficking but as demonstrated by Chinese proofs, its function is undermined by weak enforcement. On the other hand, there exist some useful mechanisms in the WTO law to combat narcotics trafficking but their weaknesses can also be easily spotted. More importantly, the alarm of the global threat of illicit trade is ringing, which requires our raising awareness to it. Recently, the UNCTAD and the OECD have already taken the initiative to discuss the collective actions, by means of conferences or reports, to deal with illicit trade. In the long run, it will be indispensable to establish an operational governance framework on the international level to effectively curb illicit trade.

Soybean peptide (SP) exhibited low intestinal absorption at oral administration due to its fragile structure under gastric digestion. Therefore, we have attempted to encapsulate peptide by cross-linkage interaction between positive charged chitosan (CS) or chitosan oligosaccharide (CSO) and negative charged peptide. The CS (or CSO) with SP nanoparticles were prepared by using ultrasonification technique. The objective of this study was to find the optimal processing method by changing concentration, pH, and homogenizing conditions. We measured physicochemical properties such as particle size, zeta-potential, encapsulation efficiency (EE%), release rate (RR) and antioxidant ability of samples. The results showed that the optimal processing method was using 0.5% (w/v) CSO (diluted by pH 3 Acetic acid buffer) mixed with 0.5% (w/v) SP (diluted by pH 6 buffer) by 9:1 ratio. Afterwards, using high-speed mixer at 12,000 rpm for 3 min, and then passed 2 times through an ultrasonicator (50% power, 3 min). In this way for processing, the particle sizes of CSO/SP nanoparticles were approximately 300 nm, zeta-potential were approximately 45 mV. In addition, the EE% and RR of CS/SP nanoparticles was higher than the CSO/SP nanoparticles. The increase in antioxidant ability of SP was attributed to the affected by CS/CSO microcapsules. In conclusion, this research can befoundation for the manufacturing process of CS/SP nanoparticles, and it was expected that the future application of this nanoparticle in food matrix.

요즘 중한 양국 문화 영역의 합작이 심화하고 있다. '원소스 멀티테리토리'모식으로 제작한 중한 영화들을 관객의 주목을 받았다. 하지만 <용하형경>과 <극한직업>이 개봉하면서 양극화 관영 평가와 현격 한 흥행 차이가 생겼다. 따라서 본 논문에서는 두 영화를 중심으로 내러티브, 캐릭터로서 현지화 원소의 운용을 대비하고 분석한다. 같은 스토리는 어떻게 다른 나라의 현지화 사회 문화를 표현할 수 있는 것에 대해 살펴보고 더 우수한 중국 영화를 만들기 위해 현지화 원소의 활용 방법을 총결해야 한다.