Sympathetic innervation stimulates β-adrenergic receptors, triggering cyclic adenosine monophosphate (cAMP) production and enhancing protein secretion in salivary gland cells. While cAMP signaling, in conjunction with Ca2+ signaling, is essential for salivary gland function, the identified cAMP-producing G-protein-coupled receptors (GPCRs) remains limited. Here, we report the presence of cAMP-producing adenosine receptors in salivary gland cells. By reanalyzing publicly available single-cell transcriptome datasets of human and mouse submandibular glands, we identified mRNA expression of adenosine A1, A2A, A2B, and A3 receptors. Additionally, we confirmed that 5’-N-ethylcarboxamidoadenosine (NECA), an adenosine A2B receptor agonist, increases cAMP levels in human salivary gland cells, suggesting a physiological role for adenosine A2B receptors. Our findings enhance understanding of adenosine’s regulatory function in salivary glands and highlight new avenues for research on cAMPproducing adenosine receptors.

As part of the 2024 research initiative, “Investigation and Discovery of Prokaryotes in Freshwater Systems,” samples were collected from diverse freshwater habitats, including both water and soil environments. Approximately 2,000 bacterial strains were isolated as single colonies and identified through 16S rRNA gene sequence analysis. Among these, 38 strains shared ≥98.7% 16S rRNA gene sequence similarities with those of known bacterial species not previously reported in Korea. These strains were thus categorized as newly recorded bacterial species in Korea. These 38 bacterial strains displayed significant phylogenetic diversities, spanning 2 phyla, 4 classes, 15 orders, 24 families, and 34 genera. These unrecorded species were classified into the following classes: Actinomycetia (with genera including Microcella, Conyzicola, Curtobacterium, Leucobacter, Microbacterium, Frigoribacterium, Lysinibacter, Streptomyces, Nonomuraea, Actinocorallia, Ruania, and Actinoplanes), Alphaproteobacteria (Paracoccus, Youngimonas, Loktanella, Corticibacterium, Neorhizobium, Onobrychidicola, Ferranicluibacter, Aureimonas, Asticcacaulis, and Novosphingobium), Betaproteobacteria (Rhodoferax, Rugamonas, and Cupriavidus), and Gammaproteobacteria (Rheinheimera, Shewanella, Kosakonia, Leclercia, Hafnia, Yersinia, Pseudomonas, Lysobacter, and Acinetobacter ). Further characterization included assessment of Gram reaction, colony and cell morphology, biochemical properties, and phylogenetic relationships. This report presents detailed phylogenetic and phenotypic characteristics of these bacterial species.

배추는 한국에서 연중 소비되는 김치의 주 원료이며, 노지에서 주로 재배되고 있다. 온실 재배 수경재배 시 스템은 기후 변화에 영향을 받지 않고 토양을 대신한 배지를 사용함으로써 토양 병원균으로부터 작물을 보호할 수 있어 재배 안정성을 확보할 수 있다. 수경재배용 배지 중 일부는 재사용이 가능하고, 이러한 배지의 조성은 작물 생 장과 품질에 영향을 줄 수 있다. 본 연구는 재사용 코이어 배지 또는 인공배지를 첨가한 배지 조성에 칼슘 공급원을 처리하여 배추(Brassica rapa ‘Bulam Plus’)를 수경재배 했을 때 배액과 생육에 미치는 영향을 알아보고자 10주동 안 수행하였다. 배지 조성은 재사용 코이어: 피트모스: 펄라이트 비율(v/v/v)을 각각10:0:0, 7:2:1, 5:3:2의 세 처리 와 각 처리에 칼슘 공급원인 CaSO4(G)와 CaO(Q)를 200g/m2 혼합한 총6가지 처리(G10:0:0, G7:2:1, G5:3:2, Q10:0:0, Q7:2:1, Q5:3:2)하였다. 배액량, 배액의 pH와 EC, 생육, 잎끝마름(Tipburn)발생을 조사하였다. 배추 생육이 증가함에 따라 모든 처리에서 배액률은 감소하였고, 처리 9주째는 20% 미만으로 감소하였다. 배액의 EC는 G 처리가 Q 처리 보다 높았으나 배액의 pH는 Q 처리가 높았다. 처리 10주째 배추의 초장, 엽수, 엽폭은 처리 간 유의성이 없었다. 엽 록소함량값(SPAD)은 G7:2:1과 G5:3:2처리에서 높게 나타났다. 잎의 당도와 건물중은 Q5:3:2처리에서 높았으며, 건물 중이 관찰되었다. 배추의 잎끝마름 발생은 처리 25일째 관찰되었으며, G7:2:1처리에서 가장 높았다. 이상의 결과를 종합할 때 CaO가 첨가되고 재사용 코이어 50% 함유된 Q5:3:2처리에서 수경 재배된 배추 생육이 양호하였다. 본 연 구는 간이 시설을 적용된 수경재배 시스템에서의 안정적 배추 재배를 위해 재사용 코이어 배지와 칼슘 공급원에 관 한 기본 정보를 제공하고자 하였다.

The Pieris napi-complex in East Asia that comprises P. melete Ménétriés, 1857, P. dulcinea (Butler 1882), and P. nesis (Fruhstorfer 1909) has been taxonomically challenging to distinguish due to their similar appearances. In this study, P. nesis, typically found in central Japan, was discovered in the highlands on Jejudo Island, the southernmost part of the Korean Peninsula. We conducted a molecular phylogenetic analysis using mitochondrial COI gene to explore the relationship between P. dulcinea and P. nesis, and confirmed that P. nesis occurs in Korea. This paper provides the morphological characteristics of P. nesis compared to P. dulcinea, along with DNA data.

Background: South Korea has recently faced record-high temperatures, which have adversely affected dairy production. Holstein cows, the primary dairy breed globally, are particularly sensitive to heat stress. In contrast, Jersey cows have shown greater heat tolerance, as demonstrated by phenotypic studies. Methods: We investigated physiological and molecular responses to heat stress in Holstein and Jersey cows by measuring rectal temperature, milk yield, and average daily gain, confirming Holstein cows’ greater vulnerability. To explore molecular mechanisms, we analyzed circulating microRNA profiles from whole blood samples collected under heat stress and normal conditions using microRNA-sequencing. Differential expression patterns were compared between the two breeds to identify biological pathways associated with heat stress. Results: Four microRNAs (bta-miR-20b, bta-miR-1246, bta-miR-2284x, and bta-miR- 2284y) were significantly differentially expressed in both breeds under heat stress (|FC| ≥ 2, p < 0.05). Notably, bta-miR-20b and bta-miR-1246 were linked to corpus luteum function and progesterone biosynthesis, while bta-miR-2284x and bta-miR- 2284y were associated with immune responses. A comparison of 11 potential heat stress-related microRNAs identified in previous studies of Holstein cows revealed consistent expression trends in Jersey cows, albeit with lower fold changes, suggesting their superior heat resilience. Conclusions: Our study highlights the physiological and microRNA-based differences in heat stress responses between Holstein and Jersey cows. Jersey cows exhibited greater resilience, supported by more stable microRNA expression profiles and improved heat stress indicators, making them a promising breed for dairy production in increasingly hot climates.

Despite the widespread use of polyaniline as a pseudocapacitor material, the cycling stability and rate capability of polyaniline- based electrodes are of concern because of the structural instability caused by repeated volumetric swelling and shrinking during the charge/discharge process. Herein, nanofiber-structured polyaniline was synthesized onto activated carbon textiles to ensure the long-term stability and high-rate capability of pseudocapacitors. The nanoporous structures of polyaniline nanofibers and activated textile substrate enhanced the ion and electron transfer during charge/discharge cycles. The resulting pseudocapacitor electrodes showed high gravimetric, areal, and volumetric capacitance of 769 F g− 1, 2638 mF cm− 2, and 845.9 F cm− 3, respectively; fast charge/discharge capability of 92.6% capacitance retention at 55 mA cm− 2; and good longterm stability of 97.6% capacitance retention over 2000 cycles. Moreover, a symmetric supercapacitor based on polyaniline nanofibers exhibited a high energy of 21.45 Wh cm− 3 at a power density of 341.2 mW cm− 3 in an aqueous electrolyte.

본 연구는 제주도 모슬포 해역에서 채집된 대형 포식성 복족류인 붉은입두꺼비고둥(Tutufa bufo) 두 개체를 대상 으로 테트로도톡신(TTX) 존재 여부를 조사하였다. 일본에 서 채집된 붉은입두꺼비고둥의 내장에서 TTX가 검출된 사례가 보고된 바 있으며, 최근 제주도 남부 해역에서 해 당 종이 혼획되고 있으나, 한국 해역에 분포하는 붉은입 두꺼비고둥의 TTX 축적에 대한 정보는 부족하다. 이에 본 연구에서는 경쟁적 효소면역분석법(cELISA) 을 사용하여 붉은입두꺼비고둥의 주요 연조직(전타액선, 구강부, 소화 선, 생식소, 아가미, 신장, 근육, 후타액선)을 분석하였다. 분석 결과, 모든 조직에서 TTX 농도는 검출 한계 미만으 로 나타났다. 그러나 TTX 축적에는 개체 간, 지역적, 계 절적 변동 가능성이 존재할 수 있으므로, 한국 해역에서 붉은입두꺼비고둥의 TTX 축적 위험을 정확하게 평가하기 위해서는 추가적인 시료 확보와 계절별 연구가 요구된다.

In today’s rapidly changing business environment, rapid decision making and effective project management are essential for business growth. This study examines how project manager competencies and organizational structures affect business performance. Successful project execution depends on the strategic use of project managers’ skills and organizational resources to maximize performance. An empirical study was conducted with 475 participants from the construction and engineering sectors. The applied analyses included multiple regression analysis and two-way ANOVA to assess how project manager competencies and organizational types affect business performance. The results of the study show that project manager competencies significantly improve business performance, especially when combined with appropriate organizational types. Effective use of organizational frameworks leads to better financial results, increased market competitiveness, and greater innovation. The results of the study are as follows: First, project manager competencies were found to have a significant positive effect on business performance. Second, the use of functional, project, and matrix organizations had a significant positive effect on business performance. This suggests that aligning organizational structures with business objectives is important for achieving optimal performance. Overall, this study provides valuable insights into the academic literature and practical applications of project management and organizational research. In addition, if we can select organizational members based on the learning effects of previous projects when operating new projects in the future, it will help reduce risks. Ultimately, it will improve the project manager’s competency level, promote the individual abilities and knowledge sharing of team members, and provide opportunities for the company to build efficient new systems. This will be evaluated as a valuable study in terms of academic and practical productivity.

목적 : 적외선 차단렌즈의 근적외선 차단율과 시감투과율을 제조방식 및 근적외선 차단제 첨가 여부에 따라 조 사하고, 근적외선 차단렌즈의 개발 방향에 대하고 논하였다. 방법 : 시중에서 유통되고 있는 국내외 브랜드의 근적외선 차단렌즈 20종(C-type 10종, M-type 5종, TMtype 5종)을 대상으로 가시광선에서 근적외선에 이르는 380~1,400 nm 영역에서 5 nm 간격으로 투과율을 측정한 후, KS B ISO 13666 표준에 따라 근적외선 차단율과 시감투과율 구하였다. 결과 : 근적외선 차단율은 TM—type이 평균 62.3%로 가장 우수하였지만, 착색렌즈에 미러코팅을 한 관계로 시 감투과율은 평균 20.2%로 매우 낮았다. M—type의 경우는 근적외선 차단제의 첨가로 인한 근적외선 차단효과가 명확하게 나타나기는 했지만, 근적외선 차단제를 첨가하지 않은 C-type의 렌즈의 근적외선 차단율보다 그 성능이 떨어졌고, 시감투과율 또한 낮았다. 근적외선 차단제가 첨가되지 않은 C-type의 렌즈들에서 근적외선 차단율은 우 수하였을 뿐만 아니라, 시감투과율 또한 무반사 렌즈 수준으로 높게 나타났다. 결론 : 최적화된 코팅설계가 적용되면 AR 렌즈 수준의 높은 시감투과율을 보이면서 TM-type의 근적외선 차단 율을 능가하는 우수한 근적외선 차단렌즈를 개발할 수 있다는 점에서 근적외선 차단렌즈의 설계 방향은 C-type이 가장 효과적이라 할 수 있다.

Light is a major external environmental factor that influences the circadian rhythm of photosynthetic organisms and various physiological phenomena, such as growth, maturation, and behavior. The number of light-reaching organisms changes depending on the season and atmospheric conditions, and the intensity and wavelength of light differ depending on the organisms inhabiting the environment. Altered light changes the circadian rhythm of fish, which is controlled by clock genes, such as period 2 (Per2), cryptochrome 1 (Cry1), and melatonin. In this study, we set the zeitgeber time (ZT; 14 light-10 dark, LD) based on the actual sunrise and sunset times and examined Per2 and Cry1 activities, levels of aralkylamine N-acetyltransferase (AANAT), and melatonin in Pholis nebulosa, a drifting seaweed species exposed to irregular light. Per2 and Cry1 levels increased during the daytime and decreased after sunset. The AANAT levels decreased during the daytime and increased during the night. Melatonin concentration was highest around midnight (ZT21, 23:30), but exhibited similar concentrations during the daytime. While the activity of Per2, Cry1, and AANAT levels exhibited a typical circadian rhythm observed in most vertebrates, melatonin concentrations did not show a significant difference between the daytime and nighttime. These findings provide insights into the circadian rhythm patterns of organisms exposed to irregular light environments, such as P. nebulosa, which differ from those of typical fish species.