The initial development plans for the six reactor designs, soon after the release of Generation IV International Forum (GIF) TRM in 2002, were characterized by high ambition [1]. Specifically, the sodium-cooled fast reactor (SFR) and very-high temperature reactor (VHTR) gained significant attention and were expected to reach the validation stage by the 2020s, with commercial viability projected for the 2030s. However, these projections have been unrealized because of various factors. The development of reactor designs by the GIF was supposed to be influenced by events such as the 2008 global financial crisis, 2011 Fukushima accident [2, 3], discovery of extensive shale oil reserves in the United States, and overly ambitious technological targets. Consequently, the momentum for VHTR development reduced significantly. In this context, the aims of this study were to compare and analyze the development progress of the six Gen IV reactor designs over the past 20 years, based on the GIF roadmaps published in 2002 and 2014. The primary focus was to examine the prospects for the reactor designs in relation to spent nuclear fuel burning in conjunction with small modular reactor (SMR), including molten salt reactor (MSR), which is expected to have spent nuclear fuel management potential.

Since interstellar objects like 1I/`Oumuamua and 2I/Borisov originate from exoplanetary systems, evenif we do not visit the exoplanetary systems,yby, rendezvous, and sample return missions of interstellarobjects can provide clues to solve the mysteries of cosmic life phenomena such as the origin of exoplanetarysystems, galactic evolution, biosignatures (or even technosignatures), and panspermia. In this paper, wereview space missions for interstellar object exploration in the stage of mission design or concept studysuch as Project Lyra, Bridge, Comet Interceptors, and LightcraftTM. We also review space missions,OSIRIS-REx and NEA Scout, designed for Near Earth Asteroids(NEA) explorations, to investigate thecurrent state of basic technologies that can be extended to explore interstellar objects in a velocity of~ 6AU/year. One of the technologies that needs to be developed for interstellar object exploration is aspacecraft propulsion method such as solar sail, which can catch up with the fast speed of interstellarobjects. If this kind of propulsion becomes practical for space explorations, interstellar object explorationswill mark a new era and serve as a driving force to provide evidences of cosmic life.

Bentonite containing >50wt% montmorillonite is being considered as a buffer material in a deep geological repository to dispose of high-level radioactive wastes (HLRW). Bentonite is considered a buffer material because of its exceptional properties such as high swelling capacity, low hydraulic conductivity, and high radionuclide sorption capacity. The bentonite buffer can be exposed to heat from the radioactive decay of HLRW and to groundwater. Water in bentonite buffer can be converted to steam under elevated temperature and pressure conditions. Previous studies reported contrasting results showing that steam treatment could decrease the swelling capacity due to changes in the surface properties from hydrophilic to hydrophobic or could not change. The contrasting results were probably because different studies used different experimental conditions and methods. Therefore, the effect of steam treatment on the bentonite properties is still unclear. The purpose of this study is to determine how the bentonite properties change after steam treatment, in particular swelling and hydrophilic properties. Two types of bentonite were used for steam treatment and analysis; Gyeongju Ca-bentonite (KJ- II) and Wyoming Na-bentonite (GCL-B). Steam treatment was performed at 150°C in an oven for various periods (7, 30, 60, and 90 days). Free swell test, X-ray fluorescence (XRF) analysis, surface-area measurement (BET), thermal gravimetric analysis (TGA), cation exchange capacity (CEC), and water uptake test were performed on steam-treated bentonite for various periods and raw bentonite. After steam treatment, some properties of steam-treated bentonite changed when compared to raw bentonite. Free swell index, which means the swelling capacity, decreased significantly as the results of previous studies. CEC and BET surface area values depended on the bentonite type. For Wyoming Na-bentonite, in which the dominant interlayer cation is a monovalent cation, CEC and BET surface area values were increased. On the other hand, Gyeongju Ca-bentonite, in which the dominant interlayer cation is a divalent cation, has no change in the above two properties. Results of XRF analysis, TGA, and water uptake test showed that these properties of both bentonites did not change after steam treatment. The results of this study confirmed that steam treatment affected the swelling and physicochemical properties of bentonite, in particular Na-bentonite. Further studies will focus on the surface properties of bentonite to investigate whether the surface properties have changed from hydrophilicity to hydrophobicity, or whether the montmorillonite structure has changed.

본 연구는 원통형 종이포트 토마토 육묘시 Diniconazole의 처리방법이 도장억제 및 근권발달에 미치는 영향을 검토하기 위하여 수행되었다. 그 결과, 엽면적, LAR, 초장, 충실도, 생체중, RGR 및 R/S 에서 시험구간 유의한 차이를 보였다. 동일한 농도를 처리했을 경우, 근권부와 지상부의 흡수도 차이로 인해 저면관수가 엽면살포에 비해 도장억제에 효과적이었다. 저면관수는 엽면시비의 10분의 1의 농도만으로도, 20~30%정도의 동일한 도장억제 효과를 얻을 수 있었다. 디니코나졸 처리에의한 근권부 반응이 흥미로웠는데, 저면관수시 총근장, 근권부피, 평균 근경 및 근단수가 증가하였다. 특히, 0.3mm 이하의 초미세근이 감소하고 0.3~0.6mm의 세근이 증가하였다. 따라서 원통형 종이포트 육묘시 저면관수를 하는 것이 기존 엽면시비에 비해 사용량이 적으면서도 도장억제 및 근권부 활착률을 높힐 수 있을 것으로 판단된다.

본 연구는 원통형 종이포트를 활용한 토마토 육묘시, 염스트레스를 활용하여 고온기 도장 억제가능성을 검토하기 위하여 수행되었다. 시험구는 K2SO4, KCl과 KH2PO4을 각 5, 10 dS·m-1로 처리하였고, 또한, 토마토 모종에 고염도의 칼륨을 처리하여 수분 및 저온스트레스 환경에서의 적응성 및 생존성을 조사하였다. 조사결과, 처리 농도가 높아질수록 지상·지하부 건물중, 옆면적, 순동화율 (NAR)이 감소하고, 경경과 충실도는 증가하였다. 수분 스트레스 처리 이후, 대조구는 심한 위조현상을 보였지만, KCl처리구는 양호하였다. 상대수분함량은 대조구에서 23%, KCl처리구에서 8% 감소 하였다. 또한, 대조구에 비하여 KCl 처리구는 저장시(9, 12 및 15°C) 모종의 손상 비율이 낮았다. 이와 같은 결과로 보아, KCl과 같은 고농도의 칼륨 처리가 원통형 종이포트 토마토 육묘의 도장 억제에 효과적이며 환경 스트레스 내성을 향상시키는 것으로 판단된다.

Thromboelastography or rotational thromboelastometry, is being increasingly utilized in cardiac surgery of late. However, it is an indirect test and is not available in all centers. Low fibrinogen levels before and after cardiopulmonary bypass (CPB) have been described to be associated with postoperative bleeding in cardiac surgery. This study explored the usefulness of reduction ratio of the fibrinogen levels before CPB (preCPB) and after CPB (postCPB) in predicting postoperative hemorrhage. A retrospective, observational study of adult patients who underwent cardiac surgery with CPB between February 2014 and January 2016 was conducted, which included a total of 264 patients. The fibrinogen levels were measured twice, preCPB and postCPB, and the fibrinogen reduction ratio was acquired [(preCPB − postCPB)/preCPB]. Postoperative blood loss, which was defined as the blood collected from the chest drain for 12 hours following arrival at the intensive care unit, was considered severe if it was more than 1,000 mL. A multivariate analysis showed that fibrinogen reduction ratio, sex, and postCPB platelet count were significantly associated with severe postoperative bleeding. However, the pre- and postCPB fibrinogen levels were not significantly associated with severe bleeding. Furthermore, a fibrinogen reduction ratio of > 41.3% was independently associated with postoperative severe bleeding, with an odds ratio of 3.472 (1.483–8.162). These results suggest that the reduction ratio of pre- and postCPB fibrinogen levels may be utilized in predicting postoperative bleeding.

This study was carried out to confirm the predatory and developmental features of N. stenoferus. We determine the host range of N. stenoferus. As a result, it was confirmed that Aphis gssypii, Myzus persicae, Planococcus citri, and Frankliniella occidentalis. N. stenoferus is thought to be able to feed on other micro pests. The test for a developmental period of N. stenoferus at 25℃ showed that the egg period was about 10 days. The nymphal period was about 18 days. Each nymphal period from 1st instar to 3rd instar nymphs was about 3 days. And the nymphal period of 4th and 5th were about 3.5 and 6 days, respectively. The female adult laid eggs in stem tissue or on leaves, and sometimes on the soaked cotton for water supply.

In Korea, two species, Anoplophora chinensis and Anoplophora glabripennis, have been recorded until now. Recently, outbreaks of Anoplophora spp. were reported locally in Seoul, Ulsan, Incheon, Gimhae, and Jeonju from 2015 to 2017. In this study, Anoplophora spp. were collected in the four regions, Ulsan, Incheon, Gimhae, and Jeonju, and their morphological and molecular characteristics were compared with those of Anoplophora spp. collected from several local regions. Twelve COI sequences of the Incheon/Gimhae/Ulsan/Jeonju populations in A. glabripennis were identical to KY357648, KY357652, and KY357651, and two COI sequences of Ulsan populations in A. chinensis were identical to AB439163. These sequences were generated from Chinese and Japanese Anoplophora samples by foreign researchers, suggesting the possibility of the invasion of Chinese and Japanese populations of Anoplophora spp. into Korea.

This study was carried out to confirm the parasitic and developmental features of A. japonica and D. suzkii was used as a parasitic natural enemy. A. japonica attacked the D. suzukii larvae and the emergence of adults were observed from D. suzukii pupae. Black spots were observed in parasitized D. suzukii larvae. Mortality of parasitized larvae, rate of parasitic and developmental feature were investigated according to developmental stages of host, D. suzukii. Mortality and rate of parasitic of D. suzukii larvae were the highest when second instar larvae were attacked. Developmental period of parasitized D. suzukii larvae showed differences to developmental stages, but there was no significant difference in developmental stage of pupal period.

To obtain information on the sanitary of indoor environment in greenhouses used for shiitake cultivation, bacteria associated with larvae and imagoes of Sciaridae flies, pest to shiitake mushroom, were isolated and identified. A total of 1,048 bacterial colonies were isolated from the flies’ larvae and 984 bacterial colonies were isolated from the flies’ imagoes. Based on molecular analysis of the 16S rDNA sequence, Achromobacter xylosoxidans and Tetrathiobacter kashmirensis of β-proteobacteria, Enterobacter asburiae and Raoultella ornithinolytica of γ -proteobacteria, Curtobacterium sp. and Microbacterium thalassium of Actinobacteria, and Penibacillus taichungensis of Firmicutes were identified from the colonies of the flies’ larvae. While, Bacillus megaterium, B. thuringiensis, Lysinbacillus sphaericus and L. fusifomis of Firmicutes, Microbacterium thalassium and Citricoccus parietis of Actinobacteria, and Enterobacter asburiae of γ-proteobacteria were identified from the flies’ imagoes. Some of the isolated bacterial species were known be human pathogens. Overall, the results of this study suggested that mushroom fly carrying human pathogenic bacteria is one of sources impact on the sanitary of indoor environment of greenhouses used for shiitake cultivation.

본 연구는 선교적 교회론의 기원 및 배경을 간략하게 살펴본 후, 선교적 교회론의 바탕이 되는 그리스도의 지상명령, 하나님의 선교, 통전적 선교, 그리고 상황화의 이슈들을 살펴보면서 선교적 교회의 관점에서 본 선교를 논의하였다. 선교적 교회론은 이미 레슬리 뉴비긴과 데이비드 보쉬와 같은 선교신학자들에 의하여 논의되었으며 1998년 대럴 구더를 비롯한 “미국 복음과 우리의 문화 네트워크”에 속한 연구자들에 의하여 더욱 활발하게 논의되었다. 예수 그리스도의 지상명령은 하나님의 선교의 중추라고 볼 수 있으며 이 전도명령에 따라 교차문화적 선교와 지역사회에 대한 봉사가 진행되어야 한다. 따라서 “우리”나 교회가 아니라 삼위일체 하나님이 주체가 되는 하나님의 선교는 복음을 토착민의 심성과 다양한 문화적 형태들에 따라서 전해야 하는 토착적인 교회의 개척과 성장은 물론 제 4의 자아, 즉 토착화 신학의 개발을 요구한다. 더 나아가서, 하나님의 선교는 하나님의 나라를 이 땅에 임하게 하기 위하여 복음전도와 사회적 책임을 통합할 수 있는 통전적 선교를 추구한다. 이 통전적 선교는 선교적 교회가 캐리그마, 코이노니아, 그리고 디아코니아를 통하여 예수 그리스도가 당시에 행하신 선교를 그분이 다시 오실 때까지 계속하는 것이다. 특히 오늘날 이 시대에 선교적 교회는 모든 경계를 뛰어넘어 예수 그리스도의 증인이 되어야 하며 변화와 화해의 사신이 되어야 한다.

World evangelization needs to be conducted by both older churches (sending churches) and younger churches (receiving churches) because the distinction between the former and the latter has disappeared. God uses great resources from the younger churches for world evangelization.The church, defined as all Christian churches without regard to denominational distinction, needs to understand the urgency of the evangelistic task. More than two-thirds of mankind have yet to be evangelized and there is a great receptivity to the gospel in many parts of the world. The church should be ashamed that so many souls have been neglected and unreached for Christ.The church needs to understand the significance of evangelism as it relates to different world cultures. Missionaries need to be sensitive to different cultures through which the gospel can be effectively communicated to different people groups. The gospel message needs to be presented in such a way that it can be meaningful to the people.The church needs to develop indigenous leadership to enable native leaders in every country to evangelize their people, plant the indigenous churches according to their needs, and extend God's kingdom. Christian leaders are not born but made through appropriate training and education. The church needs to follow Jesus Christ in terms of making disciples of all nations.The church needs to understand the spiritual conflict involved when the church is active in world evangelization. Churches are engaged in constant spiritual warfare with the principalities and powers of evil seeking to overthrow the Lord's church and frustrate its mission of world evangelization. The church needs to equip itself with the word of God and prayer.The church needs to understand the importance of religious freedom and the seriousness of religious persecution throughout the world. The church needs to pray for world leaders and call upon them to guarantee freedom of thought, conscience, and freedom to practice and propagate religion according to God's will. The church needs to understand the power of the Holy Spirit and to believe the Holy Spirit will help the church to effectively carry out world evangelization. World evangelization calls for conviction of sin, faith in Christ, a new birth, and Christian growth. The church needs to be filled with the Holy Spirit to become the true missionary church.The church needs to believe in the imminent return of the Lord Jesus Christ to consummate His salvation and His judgement. The church needs to remember that God will perfect His kingdom which anticipates the new heaven and new earth where righteousness will dwell and God will rule forever.The Lausanne Movement for World Evangelization is based on the Great Commission and the Great Commandment. The Lausanne theology of missions is based upon the Lausanne Covenant, the Manila Manifesto, and the Capetown Commitment which were officially adopted as the promise, the declaration, and the devotion of the church to carry out the world evangelization until the return of Jesus Christ.

Revelation was written by the apostle John during the reign of Roman emperor Domitianus(AD 81-96). This book is an epistle to seven churches in Minor Asia. The book of Revelation was written to encourage Christians to have victory over Satan and the evil powers during times of persecution. The Roman Empire required Christians to worship the emperors. Christians were persecuted because they refused to worship the emperor as lord. Revelation is relevant to missions in that Jesus Christ died for all humankind whether Jews or Gentile. All tribe, tongue, people, and nation will gather together to praise the Lord, the Lamb of God. Jesus’ death provided atonement for sinners regardless of race, tongue, people, and nation. Jesus’ death and resurrection provided the way for all people groups to enter the kingdom of God. Whoever believes in Jesus Christ will enter the new earth and the heaven. Revelation highlights martyrdom in the midst of persecution and suffering under the rule of Roman Empire. Christians endured persecution by keeping faith in Jesus Christ and expecting His second coming with the holy angels to judge the evil and destroy Satan’s reign. As Tertullian said, “martyr’s blood is the seed of church,” Revelation encouraged Christians to maintain their eschatological faith and spread the gospel in the midst of persecution by the Roman Empire. Revelation maintains that the slaughtered Lamb of God is worthy to open the scroll and break it’s seals. Jesus Christ is praised and worshipped by angels, living creatures, and elders. Jesus is glorified because He was slain to save the sinners. He is worthy to receive power, wealth, wisdom, honor, glory, and might because His blood provided a ransom for humankind providing propitiation to God. Jesus will be worshipped by all the saints from every tribe, language, people, and nation. Revelation shows that God’s cosmic sovereignty has been challenged by Satan and his demons since Adam and Eve fell. Likewise, the church has been challenged by Satan when carrying out its mission mandate. Satan deceives the body of Christ causing the church to doubt God’s power and justice as well as God’s grace. The church must struggle with Satan in the world; however, God has the final victory over Satan. Revelation reveals that the history of salvation began with Eden but will end with the new earth and the heaven. God’s promise in protevangelium will be fulfilled in the city of New Jerusalem. The seven churches in Asia Minor had a strong hope that they would overcome Satan’s power although they struggled with Satan in the midst of persecution and affliction. The church today needs to endure necessary hardships in the course of carrying out God’s mission. God is always with Christ’s church. The Holy Spirit is working to accomplish God’s will for the church.a

The Philippines is a beautiful country which has diversity in terms of ethnicity, language, faith, and culture. In the past, the Philippines was colonized by Spain, Japan, and America. In particular, Philippine culture is complex largely because of different cultures shared and transmitted by the members of Filipino society. This study attempted to study the main characteristics of some representative cultures of the Philippines and tried to effectively communicate the Gospel to the people on the basis of “points of contact,” revealed during study of the representative cultures. This study presented three culture themes as “points of contact” related to Filipino culture. First, this study discovered that Philippine society had mainly nuclear family units composed of father, mother, and unmarried children. Nuclear family units were usually linked to the larger family which occurred within the traditional bilocal extended family. This study utilized a house church model to evangelize the people who were living in this kind of family system. The house church model was effective on the basis of multiple human relationships of the oikos. Second, this study discovered that there were poor people who were living marginal lives, whether in rural areas or urban areas. They were suffering from severe poverty transmitted from generation to generation largely because of the structural evil caused by the corruption and inability of the Filipino government. Churches would need to support the poor more substantially and systematically in cooperation with the NGO’s and the Filipino government while understanding the culture of poverty. Third, this study discovered that there were plural religions including both traditional and popular religions. The main, traditional religion was animism prevalent throughout the Philippines, whereas popular religions were a mixture of various religions, developed according to indigenous situations of the Philippines. This study presented methods of evangelism which would effectively transform the Filipino world view in order to make them true disciples of Jesus Christ. They would need true conversion through the work of the Holy Spirit. The Philippines is a beautiful country in which Filipinos can experience real righteousness, peace, and joy in God's kingdom as the churches intentionally engage in holistic mission. Holistic mission calls for the house church model, solidarity with the poor, and evangelism, that is, making true disciples of Jesus Christ.

SERPINB3 (also known Squamous cell carcinoma antigen 1, SCCA1) is involved in apoptosis, immune response, cell migration and invasiveness of cells. It has been investigated in various types of squamous cell carcinoma. Therefore we investigated the functional role of SERPINB3 gene in human epithelial ovarian cancer (EOC) using laying hens, the most relevant animal model. In 136 laying hens, EOC was found in 10 (7.4%). We compared the expression and localization of SERPINB3 using RT-PCR, quantitative RT-PCR, in situ hybridization and immunohistochemistry, and SERPINB3 activation was detected in chicken and human ovarian cancer cell lines using immunofluorescence microscopy. Thereafter, we examined the prognostic value of SERPINB3 expression in patients with EOC by multivariate linear logistic regression and Cox’ proportional hazard analyses. In present study, SERPINB3 mRNA was induced in cancerous ovaries (p< 0.01), and it was only expressed in the glandular epithelium(GE) of cancerous ovaries of laying hens. SERPINB3 protein was localized predominantly to the nucleus of glandular epithelium in cancerous ovaries of laying hens, and it was abundant in the nucleus of both chicken and human ovarian cancer cell lines. In 109 human patients with EOC, 15 (13.8%), 66 (60.6%) and 28 (25.7%) of those patients showed weak, moderate and strong expression of SERPINB3 protein, respectively. Strong expression of SERPINB3 protein was a prognostic factor for platinum resistance (adjusted OR, 5.94; 95% Confidence Limits, 1.21-29.15). Therefore SERPINB3 may play an important role in ovarian carcinogenesis and be a novel biomarker for predicting platinum resistance and a poor prognosis for survival in patients with EOC. This research was funded by the World Class University (WCU) program (R31-10056), Basic Science Research Program (2010- 0013078) through the National Research Foundation of Korea (NRF) funded by the Ministry of Education, Science, and Technology and by the Next-Generation BioGreen 21 Program (No.PJ008142), Rural Development Administration, Republic of Korea.