The number of significant issues on many welding processes are often connected to high productivity and manufacturability at low costs. The research on welding processes in the literature has reported several research activities, but there is still scope for improvement in most industrial settings. The primary goal of this research is to determine the best super-TIG welding settings to use for groove welding. First, in order to determine the quality characteristics and risks associated with them, concepts and frameworks of quality by design (QbD) which is a new standard in pharmaceutical area in order to improve drug qualities were integrated into this process optimization. Second, stepwise experimental design approaches including a factorial design as well as a response surface methodology (RSM) were customized and performed for this specific automated super-TIG welding process. Third, based on experimental design results, the optimal operating conditions with both design space (i.e., acceptable range of operating conditions) and safe operating space (i.e., safe range of operating conditions) were obtained. Finally, a case study including QbD steps, stepwise experimental design approaches, design and operating spaces, the optimal factor settings, and their association validation results was conducted for verification purposes.

본 연구는 가치기반수용모델을 바탕으로 AI 기반 맞춤형 화장품 추천 서비스의 지각된 가치와 이용의도에 미치는 영향 요인을 규명하고자 하였다. 이를 위해 설문지 241부를 수집하여 SPSS 27.0으로 빈도분석, 요인분석, 신뢰도 분석, 상관관계분석, 회귀분석을 실시하였다. 첫째, 유용성과 즐거움은 지각된 가치에 정(+)적 영향을 미치는 것으로 나타났다. 둘째, 복잡성은 지각된 가치에 부(-)적 영향을 미치는 것 으로 나타났으나, 위험성은 유의한 영향을 미치지 않는 것으로 나타났다. 셋째, 지각된 가치는 이용의도에 정(+)적 영향을 미치는 것으로 나타났다. 그러므로 지각적 가치와 이용의도를 증진시키기 위해서는 유용한 정보롸 흥미를 유발할 수 있는 재미 요소를 제공하고, 복잡한 과정을 간단하게 축소할 필요가 있다.

본 연구는 체험형 화장품 매장에 대한 관심도가 높아짐에 따라 체험경제이론을 적용한 체험형 화장품 브랜드 소비자의 애착과 구전의도에 미치는 영향을 분석하고자 하였다. 이를 위해 설문지 234부를 수집하여 SPSS 27.0으로 빈도분석, 요인분석, 신뢰도 분석, 상관관계분석, 회귀분석을 실시하였다. 첫째, 교육적, 일탈적 체험이 브랜드 애착에 유의한 영향을 미쳤으며, 교육적 체험이 가장 큰 영향을 미치는 것으로 나타났다. 둘째, 오락적, 교육적, 심미적 체험이 구전의도에 유의한 영향을 미쳤으며, 심미적 체험이 가장 큰 영향을 미치는 것으로 나타났다. 셋째, 브랜드 애착은 구전의도에 유의한 영향을 미치는 것으로 나타났 다. 그러므로 브랜드 애착과 구전의도를 증진시키기 위해서는 흥미를 유발할 수 있는 재미 요소와 다양한 미용 정보나 지식을 제공해야 한다. 또한, 매력적인 분위기의 공간으로 가꾸고 신선하고 새로운 경험을 선 사해야 할 필요가 있다.

Carbon quantum dots (CQDs) are novel nanocarbon materials and widely used nanoparticles. They have gradually gained popularity in various fields due to their abundance, inexpensive cost, small size, ease of engineering, and distinct properties. To determine the antibacterial activity of metal-doped CQDs (metal-CQDs) containing Fe, Zn, Mn, Ni, and Co, we chose Staphylococcus aureus as a representative Gram-positive strain and Escherichia coli as a representative Gram-negative bacterial strain. Paper disc diffusion tests were conducted for the qualitative results, and a cell growth curve was drawn for quantitative results. The minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC), and IC50 were measured from cell growth curves. As a result, all of the metal-CQDs showed toxicity against both Gram-positive and Gram-negative bacteria. Furthermore, Gram-negative bacteria was vulnerable to metal-CQDs than Gram-positive bacteria. The toxicity differed concerning the type of metal-CQDs; Mn-CQDs exhibited the highest efficacy. Hence, this study suggested that CQDs can be used as new nanoparticles for antibiotics.

Entomopathogenic fungi are used to produce raw materials by applying solid culture technology using grains. But there are various problems such as low production efficiency and cross-contamination. Solvum Co., Ltd. conducted research on liquid culture technology to develop a method that can overcome these shortcomings of solid culture technology. We conducted research and development on using Beauveria bassiana 331R to observe the culture according to the seed inoculation amount in a 30 L fermenter, it was carried out at 1.0 % (v/v) and 10.0 % (v/v). Although there was a difference of 1 day, 1.0 %(v/v) seed inoculation was observed to be more than twice that, and active blastospores and yield were observed at over 95.0 %. As a results, it was determined that cost and efficient production would be possible during the culture process in mass production. Based on these experiments, a 300 L fermenter was cultured with 1.0 % (v/v) seed inoculation, resulting in a yield of 1.24E+09 CFU/mL on the 6th day of cultivation. As a result of freeze-drying using the final culture medium, it was confirmed that the production yield was improved by 113.0 % compared to the control.

This study was aimed to isolate bacterial inoculants producing chitinase and evaluate their application effects on corn silage. Four corn silages were collected from four beef cattle farms to serve as the sources of bacterial inoculants. All isolates were tested against Fusarium graminearum head blight fungus MHGNU F132 to confirm their antifungal effects. The enzyme activities (carboxylesterase and chitinase) were also measured to isolate the bacterial inoculant. Based on the activities of anti-head blight fungus, carboxylesterase, and chitinase, L. buchneri L11-1 and L. paracasei L9-3 were subjected to silage production. Corn forage (cv. Gwangpyeongok) was ensiled into a 10 L mini silo (5 kg) in quadruplication for 90 days. A 2 × 2 factorial design consists of F. graminearum contamination at 1.0104 cfu/g (UCT (no contamination) vs. CT (contamination)) and inoculant application at 2.1 × 105 cfu/g (CON (no inoculant) vs. INO (inoculant)) used in this study. After 90 days of ensiling, the contents of CP, NDF, and ADF increased (p<0.05) by F. graminearum contamination, while IVDMD, acetate, and aerobic stability decreased (p<0.05). Meanwhile, aerobic stability decreased (p<0.05) by inoculant application. There were interaction effects (p<0.05) on IVNDFD, NH3-N, LAB, and yeast, which were highest in UCT-INO, UCT-CON, CT-INO, and CT-CON & INO, respectively. In conclusion, this study found that mold contamination could negatively impact silage quality, but isolated inoculants had limited effects on IVNDFD and yeast.

Mucosa-associated lymphoid tissue (MALT) lymphoma (ML) is a type of non-Hodgkin’s lymphoma involving MALT, commonly the stomach or salivary glands, although virtually any mucosal site can be affected. ML originates from B cells in the marginal zone of MALT, and is also called extranodal marginal zone B cell lymphoma. It is a slow-growing cancer that usually responds well to treatment. A 59-year-old female presented with a 1-day history of quadriparesis and dysarthria. Up arrival at the hospital, motor power in the right upper and lower extremities was grade 3/5 according to the Medical Research Council scale, while that in the left leg was 4/5. The patient had been diagnosed with gastric ML 1 year prior, and had received antibiotics during the previous 2 weeks. The emergency magnetic resonance imaging of the brain performed at the time of presentation showed multifocal embolic infarction in the cerebral hemisphere bilaterally, which did not have a cardiac origin. Magnetic resonance angiography revealed no stenotic or occlusive lesions. Secondary prophylaxis with daily administration of 300 mg aspirin was prescribed. The patient was discharged with residual right hemiparesis 2 weeks after the onset of symptoms. Herein, we present a rare case of multifocal cerebral infarction in a gastric ML patient.