We previously reported that pyridoxine and its derivatives exert antidiabetic effects by alleviating postprandial hyperglycemia via inhibition of carbohydrate-hydrolyzing enzymes in normal sprague–dawley (SD) rats. In this study, we aimed to further evaluate whether long-term pyridoxal supplementation decreases the blood glucose levels using SD rats. SD rats were randomly assigned to groups fed a high-carbohydrate diet (66.1% cornstarch) with or without pyridoxal (4%) for 36 days. Changes in body weight, blood glucose levels, and food intake were measured daily for 36 days. Dietary supplementation with pyridoxal significantly decreased the blood glucose levels (P<0.001) and body weight (P<0.001) in mice. Glycated hemoglobin (HbA1c) levels, which are good indicators of plasma glucose concentrations over prolonged periods, were also significantly decreased over five weeks (P<0.001). Similarly, dietary treatment with Acarbose ® (0.04%), a positive control, also significantly decreased the blood glucose and HbA1c levels and body weight. Overall, our findings suggest that pyridoxal inhibits weight gain and alleviates postprandial hyperglycemia by decreasing glucose absorption and HbA1c levels.
Fueled by international efforts towards AI standardization, including those by the European Commission, the United States, and international organizations, this study introduces a AI-driven framework for analyzing advancements in drone technology. Utilizing project data retrieved from the NTIS DB via the “drone” keyword, the framework employs a diverse toolkit of supervised learning methods (Keras MLP, XGboost, LightGBM, and CatBoost) enhanced by BERTopic (natural language analysis tool). This multifaceted approach ensures both comprehensive data quality evaluation and in-depth structural analysis of documents. Furthermore, a 6T-based classification method refines non-applicable data for year-on-year AI analysis, demonstrably improving accuracy as measured by accuracy metric. Utilizing AI’s power, including GPT-4, this research unveils year-on-year trends in emerging keywords and employs them to generate detailed summaries, enabling efficient processing of large text datasets and offering an AI analysis system applicable to policy domains. Notably, this study not only advances methodologies aligned with AI Act standards but also lays the groundwork for responsible AI implementation through analysis of government research and development investments.
Sperm cryopreservation is an important method of assisted reproductive techniques and storing genetic resources. It plays a vital role in genetic improvement, livestock industrial preservation of endangered species, and clinical practice. Consequently, the cryopreservation technique is well organized through various studies, especially on Korean native cattle (Hanwoo). However, the cryopreservation technique of Korean native brindled cattle, which is one of the native cattle species in Korea, is not well organized. Therefore, it is necessary to develop a Supplementary Table technique for the cryopreservation of Korean native brindled cattle. For this purpose, it is important to first evaluate the quality of the currently produced cryopreserved sperm of Korean native brindled cattle. In this study, we randomly selected 72 individual Korean native brindled cattle semen samples collected from 8 different region research centers and used them to evaluate sperm functions. We focused on the quality evaluation of cryopreserved Korean native brindled cattle semen following the measurement of motion kinematics, capacitation status, intracellular ATP level, sperm motility, and cell viability. Then, the values of each of the eight groups were derived from various sperm parameters of nine individual samples, including sperm motility, kinematics, cellular motility, and intracellular ATP levels, which were used to compare and evaluate sperm function. Overall, differences in various sperm parameters were observed between most of the research centers. Particularly, the deviations of motility and motion kinematics were high according to the sample. Therefore, we suggest that it is necessary to develop a standard method for the cryopreservation of Korean native brindled cattle semen. We also suggest the need for sperm quality evaluation of the cryopreserved semen of Korean native brindled cattle before using artificial insemination to attain a high fertility rate.
Mimosa pudica (미모사), Argemone mexicana (멕시코 가시양귀비) Leucus aspara (꿀풀과 일종), Polygonum hydropiper (여뀌), Blumea lacera (국화과 일종) 등 5종의 식물 헥산추출물들의 팥바구미 성충에 대한 살충, 성충우화억제력 및 녹두 종실피해 방제력이 검증되었다. 그 결과, 밭바구미 성충 살충력은 35-69%이었으며, 녹두에 추출물을 처리한 후 성충우화 방제율은 33-63%, 종실 피해 방제율은 13-49%이었다. 추출물의 농도가 증가할수록 살충력, 성충우화 및 종실피해 방제율 등이 증가하는 것으로 나타났다. 이와 같이 5종의 식물 헥산추출물들은 밭바구미 친환경 방제제로 이용가능성이 있을 것으로 판단된다.
The true bug genus Paromius from Korea is revised taxonomically. It comprises the following three species: P. exiguus (Distant, 1883), P. jejunus (Distant, 1883) and P. gracilis (Rambur, 1839). Among them, P. jejunus (Distant, 1883) is recorded for the first time in Korea. The pest bug injurious to rice culture, known as P. exiguus (Distant,1883), has been recorded erroneously by the previous authors from Korea due to the misidentification, which is rectified here with the support of morphological evidence. All the species of this genus are classified with proper redescriptions, and an identification key to species is provided with illustrations.
Thermal death kinetics was examined to develop a heat treatment method to control the Pine wood nematode, Bursaphelenchus xylophilus, in wood packing materials for export goods. To determine the feasibility of microwave irradiation as an alternative treatment, we performed laboratory experiments on the blocks (200x200x250mm) of Douglas-fir artificially infested with live adults with subsequent 2.45GHz microwave energy irradiation. The 100% mortality of treated Pine wood nematode was achieved above 64℃ of the measured wood temperature, regardless of irradiated time. All measurement points in the blocks reached 64℃ within 84-312 seconds with microwave irradiation by wood weight. Likewise, the 100% mortality of nematodes were observed by hot water treatment on 62℃. We need further experimental verification, but commercial microwave (2.45GHz) treatment is a feasible alternative to conventional heat treatment to control Pine wood nematode on the wood packing materials for export goods.
Thermal death kinetics was examined to develop a heat treatment method to control the Alnus ambrosia beetle, Xylosandrus germanus, in wood packing materials for export goods. To determine the feasibility of microwave irradiation as an alternative treatment, we performed laboratory experiments on the blocks (200x200x250mm) of Douglas-fir artificially infested with live adults with subsequent 2.45GHz microwave energy irradiation. The 100% mortality of treated Alnus Ambrosia Beetle was achieved above 58℃ of the measured wood temperature, regardless of irradiated time. All measurement points in the blocks reached 58℃ within 84-312 seconds with microwave irradiation by wood weight. Likewise, the 100% mortality of breetles were observed by hot water treatment on 52℃. We need further experimental verification, but commercial microwave (2.45GHz) treatment is a feasible alternative to conventional heat treatment to control Alnus ambrosia beetle on the wood packing materials for export goods.
The purpose of this study is to examine the effects of gait training using functional electrical stimulation on the improvement of hemiplegic patients' functions for balance and gait velocity. The subjects of the experiment were determined to be 10 each hemiplegic patients who had been diagnosed with stroke or brain damage six months or longer earlier assigned to an experimental group and a control group respectively. The subjects were evaluated before the experiment using Tetrax and 10M gait tests, received gait training five times a week for four weeks using functional electrical stimulation and were evaluated after the experiment in the same method as used in the evaluation before the experiment. In order to examine differences between the experimental group that received gait training using functional electrical stimulation and the control group that was treated by functional electrical stimulation and received gait training thereafter, differences between before and after the experiment were analyzed using paired sample t-tests and differences in changes after the experiment between the experimental group and the control group were analyzed using independent sample t-tests in order to compare the two groups with each other. Experimental results showed significant differences in weight bearing, balance and gait velocity between before and after the experiment in the experimental group(p<.05). In the control group, whereas weight bearing and gait velocity did not show any significant difference between before and after the experiment(p>.05), balance showed significant differences(p<.05). Weight bearing, balance and gait velocity change rates showed significant differences between the experimental group and the control group(p<.05). In conclusion, it was indicated that gait training using functional electrical stimulation is effective for enhancing stroke patients' weight bearing rates, balance abilities and gait velocity.
The present study examined the effects of functional electrical stimulus( group 1), proprioceptive neuromuscular facilitation(group 2) and combined training of functional electrical stimulus and proprioceptive neuromuscular facilitation(group 3) with scapula adductor muscles on scapula movement, upper limb function and gait in fifteen subjects stroke patients. The training was thirty minutes a day, five times a week for six weeks, obtained result as follow, upper limb function was significant difference in the group 2(p<.05) but no significant difference in other groups. The change of weight bearing were significant difference in all the groups(p<.05), and increase of gait velocity were significant difference in all the group(p<.05). In conclusion, when applied with functional electrical stimulus, proprioceptive neuromuscular facilitation and combined training to the scapular adductor muscles, it was oberved in the course of the experiment that proprioceptive neuromuscular facilitation was the most effective treatment among the three methods applied to the scapula adductors.