항생제에 대한 내성균의 출현은 매년 급격하게 증가되고 있으며 이에 대한 약제 개발이 요구되고 있다. 특히 메치실린내성 황색 포도상구균(MRSA)은 여러 항생물질에 대하여 다제내성을 나타내므로 감염증 치료에 어려운 문제점으로 남아 있다. 이러한 감염증치료에 사용할 목적으로 임상 가검물에서 분리한 MRAS를 시험균으로 사용하여 항균 활성이 강한 방선균인 YSK-681을 선별하였다. 균주 동정을 위하여 선별된 YSK-681을 형태적, 배양학적, 생리적, 화학적 분석을 하였으며 41개의 단위 항목을 조사하여 TAXON program으로 수리 동정한 결과 주군집 29에서 속하는 Streptomyces lydicus로 동정하였다.

한국산(韓國産) 길쭉먼지벌레족(族)을 대상으로 "NC"값을 인정하지 않은 상태에서 정성적(定性的) 형태형질(形態形質)을 근거(根據)로 표현론적(表現論的) 수리분류방식(數理分類方式)을 이용(利用)한 군분석(群分析)을 실시하였다. 그 결과(結果), 비록 일부 종(種)에서는 전통분류(傳統分類) 결과(結果)와 다소 일치(一致)하지 않은 경우도 있었으나 대부분 경험적(經驗的) 분류(分類)와 유사(類似)한 경향(傾向)을 나타내었다. 그리고 대부분 종(種)들이 기대(期待)한 속(屬) 또는 아속(亞屬)내에 분포(分布)하였다.

The kinetics of flocculation of heterodisperse suspension like those in water treatment plants and natural water system are usually described by the Smoluchowski equation, which incorporates collision frequency functions for particle collisions by Brownian motion, fluid shear, and differential sedimentation. These collisionfrequeney functions have been based on a rectilinear view of collisions, i.e., one that ignores short-range forces and changes in fluid motion as particles approach one another. In this research, a curvilinear approach, i.e., one that accounts for hydrodynamic forces and particle interaction in the collision of two different size particles is developed. Collision efficiency factors of each mechanism can be calculated by trajectory analysis (fluid shear and differential sedimentation) or the solution of diffusion equation (Brownian motion). The results are presented as a set of corrections to the rectilinear collision frequency functions for each mechanism.

우리나라산 각시하늘소속에 대한 표현론적 수리분류방식과 경험적 전통분류방식의 차이 및 각종 수리결합방법에 따른 영향등을 평가하기 위하여 총 87유형별 260형질을 선정, 집괴분석을 시도하였다. 그 결과, 생식기형질의 비교분석에서 전통분류와 가장 유사하였으며, 각 분류군의 상관관계를 이해하는데 도움을 주었다.

본 연구는 개인용 컴퓨터를 이용하여 농업토목 수리구조물의 안전도평가시스템을 개발하는데 목적이 있다. 본 시스템은 상호 유기적인 관계를 가지고 있는 데이타베이스, 구조해석, 안전도분석/평가, 입출력도식화의 4가지 서브시스템으로 구성되었으며, 사용자 위주의 풀다운식 메뉴드라이빙 형태로 개발되었다. 노후손상된 구조물의 안전도평가에 사용된 주요 알고리즘은 신뢰성이론에 의한 합리적 내하력 평가방법에 기초하였다. 본 연구에서 개발된 안전도평가 시스템은 노후손상된 농업토목 수리구조물의 안전도 및 내하력 평가를 위한 효율적인 수단으로서 실무에서 널리 사용될 수 있을 것이라고 사료된다.

In the Mt. Kwangduk area, Ansan, Kyunggi-do, a hydrogeologic study was carried out with resistivity measurements from 33 points along 7 profiles with Schlumberger array and drilling from 18 points in the metamorphic rock area, which is composed of the Precambrian muscovite schist or graphite schist. The study area is covered by 25 meter thick Quaternary alluvium. The V.E.S.curves of resistivity showed N10-45° W and N10-20° E trending low apparent resistivity zone. This trend of low resistivity values is interpreted as shattered zone. The drilling data including lithologic log and exact depths of basement rocks allow to determine yield capacity, coefficients of permeability and coefficients of transmissibility. The groundwater yield capacity is related to the weathered zone and apparent resistivity anomaly but not related to the well depth. Large yield capacity of groundwater is interpreted to be the same trend as the direction of joint development and topographic relief.

In this study, the hydraulic gradient was calculated using the groundwater level and rainfall observed in the Hyogyo-ri area for a year, and the change in the hydraulic gradient according to the rainfall was analyzed. It was found that the groundwater level increased as the rainfall increased in all groundwater wells in the research site, and the groundwater level rise decreased as the altitude of the groundwater well increased. The hydraulic gradient in the research site ranged from 0.016 to 0.048, decreasing during rainfall and increasing after the end of the rainfall. As the rainfall increased, the groundwater level rise in the low-altitude area was more than the high-altitude area, and the hydraulic gradient decreased due to the difference in groundwater level rise according to the altitude. Through this study, it was found that the influence of rainfall is dominant for the fluctuation of the hydraulic gradient in the unconfined aquifer.

The objective of this study is to determine the appropriate size of the inlet pipe diameter and thereby conduct hydraulic analysis for the Korean water distribution network. To this end, the data tables for equivalent pipe diameters and outflow rates presently employed in Korea were adopted. By incorporating the table of equivalent pipe diameters, it was found that the size of the inlet pipe diameter was overestimated, which can cause shortage of water pressure and malfunctioning or insufficiency of outflow rate in the corresponding adjacent region. However, by conducting hydraulic analysis based on the table of outflow rates, relatively reasonable flow rates were observed. Furthermore, by comparing the real demand-driven analysis (RDDA) approach and demand-driven analysis (DDA) approach toward managing the huge water demand, it was observed that DDA could not effectively respond to real hourly usage conditions, whereas RDDA (which reflects the hourly effects of inlet pipe diameter and storage tanks) demonstrated results similar to that of real water supply.

We used numerical models to reliably analyze the groundwater flow and hydraulic conductivity on Jeju Island. To increase reliability, improvements were made to model application factors such as hydraulic watershed classification, groundwater recharge calculation by precipitation, hydraulic conduction calculation using the pilot point method, and expansion of the observed groundwater level. Analysis of groundwater flow showed that the model-calculated water level was similar to the observed value. However, the Seogwi and West Jeju watersheds showed large differences in groundwater level. These areas need to be analyzed by segmenting the distribution of the hydraulic conductivity. Analyzing the groundwater flow in a sub watershed showed that groundwater flow was similar to values from equipotential lines; therefore, the reliability of the analysis results could be improved. Estimation of hydraulic conductivity distribution according to the results of the groundwater flow simulation for all areas of Jeju Island showed hydraulic conductivity > 100 m/d in the coastal area and 1 45 m/d in the upstream area. Notably, hydraulic conductivity was 500 m/d or above in the lowlands of the eastern area, and it was relatively high in some northern and southern areas. Such characteristics were found to be related to distribution of the equipotential lines and type of groundwater occurrence.