The baculovirus-insect cell expression system has been widely used method for the recombinant protein expression. The present study has several limitation. In this study, we constructed vectors consisting of transcriptional enhanced factor and promoter that improve the expression level. To confirm the usefulness of these vector system, Human papillomavirus (HPV) VLPs have been expressed by baculovirus hyper expression system. HPV VLPs were purified using a CaptoTM Core 700 (GE Healthcare Life Sciences) chromatography approach. Baculovirus hyper expression system production efficiency was influenced by the HPV VLPs production. HPV VLPs vaccination to BALB/c mice induced the generation of antibody confirmed by ELISA. This study could provide improvements on the vaccine production for the development of VLP vaccines high expression of useful heterologous proteins.

Introduction According to the Federation of the Swiss Watchmaking Industry (FHS) in 2017, Switzerland occupies approximately 3% of the global market regarding the quantity of watches. As for value, Switzerland represents 54% of global sales that is 21 billion USD. About 95% of luxury watches with price starting from 1,000 USD are stamped "Swiss Made.” Thus, the Swiss watch industry has become an integral part of the luxury universe. However, it‟s not an easy task to get a place in this luxury market of reference. According to the estimation made by the Institute of Watch Marketing, there are approximately 200 active Swiss watch brands on the market today. In order to create an uncontested market space and stand out from the competition luxury watch brands are obliged to create a new way of dealing with concurrence. The majority of brands chose the positioning at the top of a watch pyramid. First of all, it is an economic issue: according to the recent Deloitte report (2017) on watchmaking industry, the most important increase is in the category of watches belonging to the “Haute Horlogerie” segment. While other categories have been steadily losing their shares in exports for years, the high-end category of watches is growing considerably. In the last two decades, luxury brand management has attracted much interest and discussions in academic and business circles. Among the business leaders and scientists, the debates were related to the challenges and paradoxes associated with luxury branding and management that emerged as a result of the evolution of the field (Okonkwo, 2007; Kapferer, 2008 Chevalier and Mazzalovo, 2008, Dubois B., Laurent G., et Czellar S, 2001). In order to create and maintain the position of a strong luxury brand, a number of key elements have been identified as crucial and divergent within the scientific literature (Sicard, 2008; Fionda and Moore, 2008, Merle, Chandon and Roux, 2008). Vigneron and Johnson (2004) proposes key luxury dimensions that managers should establish and monitor for creating a lasting luxury brand. Nevertheless, in our opinion there are no many researches explaining hyper luxury segment growth and the upward expansion of the Swiss luxury watchmaking to the hyper luxury. To our knowledge, there is no scientifically accepted definition of the hyper luxury segment. We attempt to define hyper luxury watch brands as “Haute Horlogerie” watch brands with a unique positioning based on the personal-oriented perceptions of customers, high experiential value and proprietary manufacturing know-how, offering mainly mechanical watches in a price range starting at roughly 60„000 USD and then passing to the price categories of 100‟000-500‟000-1‟000‟000 USD for a watch. In order to shed light on upward expansion to Hyper Luxury trend in Swiss luxury watchmaking we should formulate the following research question: What kind of resources to optimize and which processes to implement in order to create resource-based competitive advantage in a highly competitive market of Swiss luxury watchmaking? Methodology To gain a deeper understanding of the upward expansion to hyper luxury in Swiss watchmaking industry we proceed to qualitative research (semi-structured interviews with 20 CEO and Marketing managers) among watchmaking companies. We specifically focused on top managers involved in the product development and decision making and management processes. The key issues addressed were: definition of the key company‟s resources, information management, market sensing, innovative approaches in management, sources of value creation for customers and differentiation strategies, managerial vision and firm-specific practices and procedures. Qualitative research methods were selected for this study with the aim to generate data rich in details and embedded in context. This study will allow us to enlarge and enrich previous theoretical findings and illustrate it with practical evidences. Conceptual framework Last decades have seen an important economic shift from manufacturing to information and knowledge-driven services. This shift has been accompanied by an increase in the importance of intangible assets and capabilities. Thus the source of competitive advantage has changed from mostly manufacturing assets to market based intangible assets and capabilities (Ramaswami et al., 2009). The resource-based theory (RBT) provides an important framework in explanation and prediction of the firm‟s competitive advantage and superior performance based on market based insights (Barney and Arikan, 2001, Vorhies and Morgan, 2005). RBT considers a company as an idiosyncratic mix of resources and capabilities that are available for application by various departments in the company and are very difficult to imitate by competitors (Teece et al., 1997). Accordiang to Barney and Hesterly (2012), sustainable competitive advantage results only if resources are simultaneously valuable, rare, imperfectly imitable, and exploitable by the firm‟s organization (VRIO). This VRIO framework has acknowledged that resources need to be leveraged effectively by the organization, instead of simply possessed by the firm. Even if a resource is valuable, rare, and imperfectly imitable, a firm must be “organized to exploit the full competitive potential of its resources and capabilities. According to Newbert (2008), performance improvement is not directly a function of the value or rareness of a firm‟s resource-capability combinations but rather of the advantages it creates from their exploitation. Then, through insightful theoretical development researchers have expanded the RBT into the concept of dynamic capabilities. Specifically, dynamic capabilities are defined as the ability to build, integrate, and reconfigure internal and external intangible resources to address rapidly changing environments (Winter, 2003). Teece et al (1997) and Eisenhard and Martin states that sustained competitive advantage could be based on the firm‟s renewal and reconfiguration of its resources and capabilities through dynamic capabilities. The dynamic capabilities view changes from the resource-based view of the firm (Barney, 1991), by its attempts to the explanation of the conditions under which firms achieve competitive advantage based on their resources and capabilities (Molina et al., 2014). Furthermore, researchers have increased conceptual understanding of the role of marketing in enabling firms to create and sustain competitive advantage and superior performance (Ramaswami et al, 2009). In accordance with potential to improve business performance, some studies (Bruni and Verona, 2009), have introduced the term „Dynamic Marketing Capabilities‟ (DMCs hereafter). In fact, DMCs are specifically focused on releasing and integrating market knowledge that helps firms evolve. Developing DMCs could constitute the real basis for sustainable competitive advantage and superior performance in most competitive sectors (Molina et al, 2014). Fang and Zou (2009) define DMC as the responsiveness and efficiency of cross-functional business processes for creating and delivering customer value in response to market changes. It is this focus on customer value that distinguishes DMCs from dynamic capabilities in general. According to Bruni and Verona (2009) DMC are those capabilities aimed specifically at developing, releasing and integrating market knowledge that helps firm evolve. Main findings and analysis Analysis of semi-structured interviews with the CEO and marketing managers of the Swiss luxury watchmaking companies lead us to a number of findings concerning the role of DMC for the hyper luxury brand expansion. The exploratory study confirms many of the elements presented in the conceptual part of this article. Most of the Swiss high-end watchmaking companies are traditionally founded focusing on specific kind of watch and technological expertise in it. Often, these companies tend to develop and grow by mastering their technological competences. As it comes from our research nowadays rare are companies that uses dynamic DMC. Even if the majority of companies confirmed the importance of DMC, it is very difficult to implement it on practice due to the complexity of the numerous stages of industrial production, various operations and partners. Meanwhile, there are some companies that managed to integrate the concept of dynamic marketing capabilities and improve their performance. A deeper questioning into their management practices revealed that they are achieving these results because of the sophisticated and effective way of implementation marketing insights coming from partners and clients. These high performing companies generate growth because of their particular focus for constant improvement of their marketing activities. “The main idea is to question all the time our way of working and to elaborate more sophisticated marketing mix than most of our competitors. For us, sophistication of our watches has the same importance as sophistication of our marketing activities”. Our research pointed out that these few firms of Swiss luxury watchmaking industry, that successfully accomplish the search and gap-assessment stages concerning dynamic marketing capabilities have an advantage over rivals. The market-based identification of valuable resources and internal management of intangibles help managers recognize the need for improvement. In a case of such particular industry as Swiss watchmaking where any considerable changes are very costly and time consuming the companies that applies DMC through small steps and project-based development assure their presence and adaptability to the globalized changes of the economy. “Swiss luxury watchmaking industry strongly related to the overall economic and social changes in the world. So we need to be constantly aware and understand global trends, for example, emerging categories of customers and their expectations towards luxury products”. Thus, dynamic marketing capabilities are considered as very important value creation drivers. We identified marketing intelligence, customer relationships and professional networks as the most important elements for additional value creation. “It is clear that information is very important in order to stay “up to date” with the market. As most of decisions and processes depends on the feeling of the current situation on the market and clients, it’s very important to gather as much information as possible. There is no one source of information, but the multitude of different sources and various information as a puzzle helps to construct the right vision”. Organizational capabilities, information sharing and collaboration between various departments are directly related to new value creation. As it came from the qualitative analysis the main conditions are the “openness” of management vision and strategic flexibility of decision makers. Moreover, high-performing companies participated in our research confirmed that it is very important to adopt an entrepreneurial attitude and to implement “participative” way of collaboration. “On the initial stages of product development, all departments are invited to give their feedback on the product. We organize regularly a brainstorming in order to obtain various perspectives. Cross-functional teamwork brings more value”. Those companies who could create some sort of flexibility in organization of production find themselves mostly on the niche market of hyper-luxury with a very personalized, sometimes even “co-created” watches. In this approach, it is a client, his visions and his preferences that are incorporated into the watch through its design, configuration, functions and complications. This phenomenon also confirms the recent trends on the luxury market of ultimate personalization and unique experience creation that accompanying the product. “People who could acquire almost everything that they want are looking for new experiences. Millennials are willing to pay higher price for personalized high-end and luxury items. The watch became not only the symbol of the status of its owner, but the reflection and continuation of the personality of a client. In this case a unique watch for somebody unique is a great concept”. Managerial recommendations Our research revealed that the concept of the dynamic marketing capabilities as a part of intangible resources of the company could be very beneficial for swiss luxury watchmaking companies in the process of expansion to hyper luxury segment. Managerial contribution of this article lies in new approach illustration that could be used as a support for strategic decision-making in Swiss watch-making companies. The concept of dynamic marketing capabilities is a very complex phenomenon. As a first step for improvement it would be important to get more informed and deeply understand it. In order to create more value and better performance, it is important to deep “intuitive” way of decision making and to implement more explicitly insights coming from practice. Traditionally very segmented industry of Swiss luxury watches is on the road to changes due to radical social and economic changes around the world. Nowadays, company growth and performance requires connecting many elements across various sources of data. There are more opportunities and synergies in initial collaboration on the basic steps of the expansion to hyper luxury segment of watches then filling in the gaps that were not considered in the beginning. Feedbacks from customers and partners could be the most valuable data sources for sustainable changes and following up current trends on the market. Extensive data gathering and analysis, flexibility and learning has a direct impact to the performance. The more internal and external sources engaged into the flexible management and decision making process, the better performance and customer value it could bring. Nowadays, customer is placed in the center of the most of successful businesses. The level of understanding of the customer preferences and values turning to solid insights that could help for better and more efficient performance and decision making processes. Co-created value with customer‟s insights will help to achieve more recognition, exclusivity and appreciation from customers. Direct interactions with wealthy individuals are the main differentiators and value creation mechanisms of a hyper luxury segment of watches. There are numerous opportunities to engage customers in a dialogue instead of traditional for Swiss luxury watchmaking industry one-directional communication. Largely applied in other industries (luxury cars, yachts etc.) this approach is considered to be a niche in the luxury watchmaking. Thus, in our opinion even in the highly traditional industry as Swiss luxury watchmaking it is of great importance to understand and try to implement this dynamic approach and to adopt “Bottom up” management practices. From managerial point of view it is important to encourage curiosity, open-mindedness and cross-departmental communication of the employees. Our key managerial recommendation would be to state that in order to gain competitive advantage, information from the markets, partners and clients should be translated into actionable plans that, once applied, tend to yield concrete results. This transition from data to reconfiguration of processes represents the path that creates more value and competitive advantage in a highly competitive industry. More specifically, firms aimed to compete on the basis of the superior customer service and expansion to the “hyper luxury” sector are advised to invest into building new type of relationship and more dynamic organizational process based on the insights coming from various partners. Limitations and further research avenues The resource advantage theory was predominantly constructed on the theoretical level. In our opinion, such approach could be considered as the key drawback of scientific discourse. Recognition that science and practice produce distinct forms of knowledge has been longstanding. According to Van de Ven (2007), the gap between theory and practice may be a knowledge production problem. The aim of the current research is to suggest a vice versa point of view and to highlight empirical evidence coming from practice. The theoretical contribution of this article to the academic discussion lies in explaining the expansion to the Hyper Luxury Watchmaking Segment based on intangible assets management. We contribute to the development of RBT with its insights deriving from Swiss luxury watchmaking industry. These issues helps us to come up with managerial recommendations and thus to contribute to the advancement of the RBT. The main limitation of this research is in the nature of our research. The exploratory research helped us to identify the key elements in expansion to hyper luxury watch segment by Swiss luxury watchmaking companies. However, this does not allow us to understand the depth of this phenomenon. In order to confirm this results the more profound and focused analysis is needed. It could help to understand deeper micro-foundations of DMC. In addition to that, in our opinion a detailed case study of the firm with outstanding DMC‟s would be particularly valuable. Otherwise, to test quantitatively what are the links between various elements is also a promising avenue for this research.

In recent years, imbalanced data is one of the most important and frequent issue for quality control in industrial field. As an example, defect rate has been drastically reduced thanks to highly developed technology and quality management, so that only few defective data can be obtained from production process. Therefore, quality classification should be performed under the condition that one class (defective dataset) is even smaller than the other class (good dataset). However, traditional multi-class classification methods are not appropriate to deal with such an imbalanced dataset, since they classify data from the difference between one class and the others that can hardly be found in imbalanced datasets. Thus, one-class classification that thoroughly learns patterns of target class is more suitable for imbalanced dataset since it only focuses on data in a target class. So far, several one-class classification methods such as one-class support vector machine, neural network and decision tree there have been suggested. One-class support vector machine and neural network can guarantee good classification rate, and decision tree can provide a set of rules that can be clearly interpreted. However, the classifiers obtained from the former two methods consist of complex mathematical functions and cannot be easily understood by users. In case of decision tree, the criterion for rule generation is ambiguous. Therefore, as an alternative, a new one-class classifier using hyper-rectangles was proposed, which performs precise classification compared to other methods and generates rules clearly understood by users as well. In this paper, we suggest an approach for improving the limitations of those previous one-class classification algorithms. Specifically, the suggested approach produces more improved one-class classifier using hyper-rectangles generated by using Gaussian function. The performance of the suggested algorithm is verified by a numerical experiment, which uses several datasets in UCI machine learning repository.

The baculovirus expression vector system (BEVS) is an effective and widely used system for the production of recombinantproteins in insect cells or larvae. However, the expression efficiency of recombinant proteins using the polyhedrin promotercould not acquire the protein yields observed for native polyhedrin. In this study, we tried to develop hyper expressionvector by the optimal combination of previously reported various enhancer factors. The selected enhancer factors for optimalexpression consists homologous region5 (hr5), VP39 promoter and burst sequences. Seven recombinant viruses were madeto compare EGFP expression level. Each recombinant viruses showed different expression levels respectively, and themost of expression level was observed with higher than those of the previous vectors. This study suggests a new optionfor hyper expression of useful recombinant protein using the BEVS.

The baculovirus expression vector system (BEVS) is an effective and widely used method for the production of recombinant proteins in insect cells or larvae. However, the expression efficiency of foreign proteins using the polyhedrin promoter could not obtain the protein yields observed for native polyhedrin. To enhance the production efficiency of foreign protein in baculovirus expression system, the effects of various enhancer factor were investigated by fusion expressing them with the enhanced green fluorescent protein (EGFP). As a hyper expression factor, the optimal hyper BEVS was constructed by combining Hr5 sequence, VP39 promoter and Burst sequences. Additionally, the proteins expressed by the hyper expression system was markedly increased. This study suggests a new option for higher expression of useful foreign recombinant protein using the BEVS.

The extragalactic background suggests half the energy generated by stars was reprocessed into the infrared (IR) by dust. At z1.3, 90% of star formation is obscured by dust. To fully understand the cosmic star formation history, it is critical to investigate infrared emission. AKARI has made deep mid-IR observation using its continuous 9-band filters in the NEP field (5.4 deg2), using 10% of the entire pointed observations available throughout its lifetime. However, there remain 11,000 AKARI infrared sources undetected with the previous CFHT/Megacam imaging (r ~25.9ABmag). Redshift and IR luminosity of these sources are unknown. These sources may contribute signicantly to the cosmic star-formation rate density (CSFRD). For example, if they all lie at 1< z <2, the CSFRD will be twice as high at the epoch. We are carrying out deep imaging of the NEP eld in 5 broad bands (g; r; i; z; and y) using Hyper Suprime-Camera (HSC), which has 1.5 deg field of view in diameter on Subaru 8m telescope. This will provide photometric redshift information, and thereby IR luminosity for the previously-undetected 11,000 faint AKARI IR sources. Combined with AKARI's mid-IR AGN/SF diagnosis, and accurate mid- IR luminosity measurement, this will allow a complete census of cosmic star-formation/AGN accretion history obscured by dust.

목 적 : 자기공명영상(MRI)의 발달은 소아신경계의 병리학적 과정을 이해하고 진단하는데 중요한 역할을 하고 있으며 그 검사 건수는 나날이 증가하고 있다. 하지만 이같은 장점에도 불구하고 소아의 Brain MR 검사는 환자에게 주의를 주거나 Sedation을 하여 검사를 진행하지만 움직임, 소음 등으로 인하여 실패하는 경우가 발생한다. 고해상력의 영상 획득이 가능한 3.0T의 경우 1.5T에 비해 SAR가 약 4배 증가하게 되며, 최근 미국 소아과학회에서는 어린이가 어른보다 전자파에 더 큰 영향을 받기 때문에 더욱 주의하여 관리해야 한다고 주장하고 있다. 이때, 기존의 TSE가 아닌 다양한 Refocusing FA를 사용하는 Hypere-TSE은 동등한 SNR을 유지하면서 SAR를 감소시키기 때문에 그 해결책이 될 수 있다. 또한, MR 검사 시의 소음은 Gradient의 빠른 Switching을 통해 발생하는데, 이러한 기존의 소음 감소를 위한 Gradient mode인 Whisper mode는 Scan time이 증가하는 등의 단점이 있었으나 최근 E11 Upgrade를 통해 도입된 Acoustic noise reduction는 이를 개선하여 동등한 Scan time과 향상 된 소음 감소 효과를 가져왔다. 이에 본 연구에서는 소아 Brain MRI 검사 시 Hyperecho와 Acoustic Noise Reduction을 이용하여 Image quality를 동등하게 유지하면서 소아를 더욱 안전하고 안정된 환경에서 검사할 수 있는 방법을 제안하고자 한다. 대상 및 방법 : 장비는 SIEMENS사의 3.0T SKYRA(Germany)와 32ch Head coil을 사용하였고, Spherical Phantom D165(Siemens, Germany) 및 만 15세 이하의 소아 환자 20명(남자 12, 여자 8, 평균연령 6세)을 대상으로 하였다. Hyper-TSE와 Acoustic noise reduction을 사용했을 때와 사용하지 않았을 때의 T1 Dark fluid(TR: 2000, TE: 9, TI: 900, Matrix: 384*307, FOV: 200*200, NEX: 1) T2WI(TR: 6000 TE: 103, Matrix: 448*269, FOV: 200*200, NEX: 2), T2 FLAIR(TR: 9000, TE: 84, TI: 2500, Matrix: 320*192, FOV: 200*200, NEX: 1)에서 비에스코리아사의 디지털 소음 측정기를 통하여 Isocenter에서 150㎝ 거리에서의 소음을 측정하였고, SAR와 SNR은 Siemens NUMARIS/4 - syngo MR E11로 Gray matter, White matter, Eye ball을 관심 영역 0.02㎠ 측정하여 IBM SPSS Statistics v22.0을 통해 정량적 분석을 하였다. 결 과 : 정량분석 결과 Hyper-TSE와 Acoustic noise reduction을 사용했을 때는 사용하지 않았을 때에 비해 SAR가 T1 Dark fulid에서 -26%, T2에서 -33%, T2 FLAIR에서 –33%로 감소되었으며, 소음은 T1 Dark fulid에서 -14%, T2에서 -16.6%, T2 FLAIR에서 –16.1% 감소하였고, SNR은 T1 Dark fulid에서 GM: 17%, WM: 15%, Eye ball: 12%, T2에서 GM: 10%, WM: 14%, Eye ball: 14%, T2 FLAIR에서 GM: 3%, WM: 9%, Eye ball: 7%로 증가한 것으로 나타났다. CNR은 T1 Dark fulid에서 14%, T2에서 3%, T2 FLAIR에서 –19%로 증감된 것으로 나타났다. 비모수 대응표본 Wilcoxon T검정을 실시한 결과 대부분의 값에서 유의한 차이(p<.05)가 있는 것으로 나타났다. 결 론 : Hyperecho를 사용하게 되면 SNR을 유지하면서 SAR를 상당히 감소시킬 수 있다는 것과 Acoustic noise reduction을 사용할 경우 동일하거나 약간의 검사 시간 증가와 함께 많이 조용하게 된다는 이론적 사실을 바탕으로 안전하고 안정된 환경을 만들기 위해 노력하였다. 이번 연구를 통해 Hyperecho 및 Acoustic noise reduction을 사용할 경우 기존의 Sequence와 비교하여 SAR와 소음은 감소시키면서 SNR과 CNR 값은 동등하거나 증가된 영상을 얻을 수 있고 이를 통하여 소아 환자에게 더욱 안전하고 안정된 환경을 제공하고 효과적이며 진단 가치 높은 영상을 얻을 수 있으리라 사료된다.

The baculovirus expression vector system (BEVS) is an effective and widely used method for the production of recombinant proteins in insect cells or larvae. However, the expression efficiency of foreign proteins using the polyhedrin promoter could not obtain the protein yields observed for native polyhedrin. To enhance the production efficiency of foreign protein in baculovirus expression system, the effects of various polyhedrin fragments were investigated by fusion expressing them with the enhanced green fluorescent protein (EGFP). Among the fusion-expressed protein in nucleus and cytoplasm, the most hyper-expression was observed in the fusion of amino acids 19 to 110 and 32 to 59 of polyhedrin. Additionally, the several proteins expressed by the partial polyhedrin-fused expression system was markedly increased. However, we identified that hyper-expression of target protein varied depending on the partial polyhedrin. Therefore, we constructed the virus inducible partial polyhedrin fusion transient expression system. This system amenable for screening of suitable partial polyhedrin to produce the target protein. The present study suggests a new option for higher expression of useful foreign recombinant protein using the partial polyhedrin fusion expression in baculovirus.

HyPer is the genetically encoded biosensor of intracellular hydrogen peroxide (H2O2), the most stable of the reactive oxygen species (ROS) generated by living cells. HyPer has a high sensitivity and specificity for detecting intracellular H2O2 by confocal laser microscopy. However, it was not known whether high speed ratiometric imaging of H2O2 by HyPer is possible. We thus investigated the sensitivity of HyPer in detecting changes to the intracellular H2O2 levels in HEK293 and PC12 cells using a microfluorometer imaging system. Increase in the HyPer ratio were clearly evident on stimulations of more than 100 μM H2O2 and fast changes in the HyPer ratio were observed on ratiometric fluorescent images after H2O2 treatment. These results suggest that HyPer is a potent biosensor of the fast temporal production of intracellular H2O2.

A level set based topological shape optimization method for nonlinear structure considering hyper-elastic problems is developed. To relieve significant convergence difficulty in topology optimization of nonlinear structure due to inaccurate tangent stiffness which comes from material penalization of whole domain, explicit boundary for exact tangent stiffness is used by taking advantage of level set function for arbitrary boundary shape. For given arbitrary boundary which is represented by level set function, a Delaunay triangulation scheme is used for current structure discretization instead of using implicit fixed grid. The required velocity field in the actual domain to update the level set equation is determined from the descent direction of Lagrangian derived from optimality conditions. The velocity field outside the actual domain is determined through a velocity extension scheme based on the method suggested by Adalsteinsson and Sethian(1999). The topological derivatives are incorporated into the level set based framework to enable to create holes whenever and wherever necessary during the optimization.

This essay attempts to trace the various implications of bodies which are made from the integration of human body with technologies in the contexts of art. I investigated the body transformations and mediation-effects from combinations of human body with chips, prostheses, surgical operations in artistic performances. The hyper-mediated bodies in this essay means the bodies that encounter with technology directly, are mediated, added, and metamorphosed or modified by technology, and are fascinated with technology, confirmed by medial diversity and mediation. Technology may be machines or not. Hypermediated body tends to stress not finished result but the process itself as the heterogeneous. It also has the postmodern deconstructive characteristics of body of deformation, fragmentation, inter-penetration, hybridization, and diversity. The notion of‘ hyper-mediation’ comes from Jay David Bolter and Richard Grusin’s Remediation, Understanding New Media(2000). I studied the real practices of integration of body and technology in art, not only ways of artistic expression but also the various meanings of the very point of integration. My standpoint on‘ Posthuman’ concept which we will meet inevitably in the near future, is neither negative or positive. I am just concerned with the reconstruction of bodies in art, and with the ways how artists accept and express these situations. There are delicate dialectical meanings in the point or edge where body and technology meet and contact. They arouse from the process of acknowledging of inter-construction, integration of human and technology. They also run parallel with theoretical methodologies from gender study, philosophy, literary criticism and visual culture, psychoanalysis and deconstruction, cyber-theory, biomedicine, and phenomenology etc. Through these means, they attend to the dialectics between subject and object, flesh(meat) and machine, metaphor and materiality, figuration and literality, inside and outside, internalization and externalization, body and technology, human and posthuman. These opposite elements are linked in the relations of mediation and transformation each other. The Hyper ― Mediated Bodies in the Age of New Media Jeon, Hyesook(Ewha Womans University, Assistant Professor) In this essay, I treated Australian artist Stelarc and French artist Orlan's hyper-mediated body performances. Their bodies are the modified and added constructions, and they have accepted the very liminality itself and the way of‘ becoming’ through cyborg-like encounter(human/machine) and surgical operations. They opened a new understanding of hyper-mediated bodies in the age of new media.

The advent of various arts and remarkable development of mass media since 1980s accelerate fashion photographs' advancement. The expression of fashion through photographs can represent characteristics of ages, societies, cultures, traits of designers and techniques of photographers. In addition, that is the tool which contains economical role as a product and artistic role as photos. Therefore, this study examines hyprt-reality images in editorial fashion photographs. Hyper-reality means the reproduction which represents the reality of life more actually. Hyper-reality through photographs elevates reality of virtual things and creates the confused situation which haunts the boundary between reality and reproduction. This study classifies the hyper-reality in editorial fashion photographs into three groups by their external traits, ideal reality, collapse of reality, and restoration of reality. First, ideal reality is represented as harmony among fashion, characters, and space, causality of fashion with time and circumstances, positive will, and melting with nature. Second, collapse of reality is expressed as in harmony between fashion and situation, violence, fetishism and symbol of death. Third, restoration of reality is shown as recurrence to nature and images of utopia to express dignity of life.

In this work, the dispersion behavior of particles in binary aluminum (Al)-copper (Cu) cast alloy was investigated with respect to Cu contents of 20 (hypoeutertic), 33 (eutectic) and 40 (hypereutectic) wt.%. In cases of hypo and hypereutectic compositions, SEM images revealed that the primary Al and phases were grown up at the beginning, respectively, and thereafter the eutectic phase was solidified. In addition, it was found that some of particles can be dispersed into the primary Al phase, but none of them are is observed inside the primary 6 phase. This different dispersion behavior of particles is probably due to the difference in the val- ues of specific gravity between particles and primary phases. At eutectic composition, particles were well dispersed in the matrix since there is few primary phases acting as an impediment site for particle dispersion during solidification. Based on the experimental results, it is concluded that particles are mostly dispersed into the eutectic phase in binary Al-Cu alloy system.