The demand for automated diagnostic facilities has increased due to the rise in high-risk infectious diseases. However, small and medium-sized centers struggle to implement full automation because of limited resources. An integrated molecular diagnostics automation system addresses this issue by integrating small-scale automated facilities for each diagnostic process. Nonetheless, determining the optimal number of facilities and human resources remains challenging. This study proposes a methodology combining discrete event simulation and a genetic algorithm to optimize job-shop facility layout in the integrated molecular diagnostics automation system. A discrete event simulation model incorporates the number of facilities, processing times, and batch sizes for each step of the molecular diagnostics process. Genetic algorithm operations, such as tournament, crossover, and mutation, are applied to derive the optimal strategy for facility layout. The proposed methodology derives optimal facility layouts for various scenarios, minimizing costs while achieving the target production volume. This methodology can serve as a decision support tool when introducing job-shop production in the integrated molecular diagnostics automation system

This study was various sensitive to a customer requirement and sensitive to the market environment of cosmetics with the manufacture company the low. Consequently we arrange the making line properly and are there even though we make a productivity enhance with the personnel expenses reduction to the quality enhance. We do the supplementation with existing U-line the defect of Cell-line of the making method. We try we substitute and to present the improvement direction to apply at the characteristic of the making company so that we are soft.

This paper proposes service layout strategy considering service characteristics by the use of benchmarking production system such as layout by P-Q chart, improvement tool, automated system, Toyota production system and lean production system. This paper represents operation methodology of statistical process control using control chart for service performance outcomes.