RAM represents reliability, availability, and maintenance, and is a key performance indicator that is utilized throughout the life cycle of the weapon system from the stage of requesting to disposal. If the RAM target value is set to a too high value, development may be delayed or development cost may be increased. If it is set to a too low value, frequent failures may occur during training, or a problem may arise that the number of available weapon systems is insufficient. The currently most used method to set the RAM target value is to write an operation mode summary and calculate it through an equation. However, as the definition of the operation mode is not standardized, different RAM target values may be set depending on the authoring organization. This study aims to analyze the current situation and suggest an alternative to this problem.

When considering military operations that require rapid response time, forward supply operation of various type of ammunition is essential. Also, t is necessary to supply ammunition in a timely manner before an ammunition shortage situation occurs. In this study, we propose a mathematical model for allocation of ammunition to ammunition storehouse at the Ammunition Supply Post (ASP). The model has several objectives. First, it ensures that the frequent used ammunition is stored in a distributed manner at a high workability ammunition storehouses. Second, infrequent used ammunition is required to be stored intensively at a single storehouse as much as possible. Third, capacity of the storehouse and compatible storage restriction required to be obeyed. Lastly, criticality of ammunition should be considered to ensure safety distance. We propose an algorithm to find the pareto-based optimal solution using the mathematical model in a reasonable computation time. The computational results show that the suggested model and algorithm can solve the real operational scale of the allocation problem.

A safety assessment of radioactive waste repositories is a mandatory requirement process because there are possible radiological hazards owing to radionuclide migration from radioactive waste to the biosphere. For a reliable safety assessment, it is important to establish a parameter database that reflects the site-specific characteristics of the disposal facility and repository site. From this perspective, solubility, a major geochemical parameter, has been chosen as an important parameter for modeling the migration behavior of radionuclides. The solubilities were derived for Am, Ni, Tc, and U, which were major radionuclides in this study, and on-site groundwater data reflecting the operational conditions of the Gyeongju low and intermediate level radioactive waste (LILW) repository were applied to reflect the site-specific characteristics. The radiation dose was derived by applying the solubility and radionuclide inventory data to the RESRAD-OFFSITE code, and sensitivity analysis of the dose according to the solubility variation was performed. As a result, owing to the low amount of radionuclide inventory, the dose variation was insignificant. The derived solubility can be used as the main input data for the safety assessment of the Gyeongju LILW repository in the future.

본 연구는 다양한 항생제 내성을 갖는 Salmonella enterica subsp. enterica serovar Typhimurium ATCC 19585 (STWT), S. Typhimurium KCCM 40253 (STKCCM), ciprofloxacininduced S. Typhimurium ATCC 19585 strains (STCIP), and S. Typhimurium CCARM 8009 (STCCARM)에 대한 phage의 흡착 및 용균 특성을 평가하였다. PBST-10, PBST-13, PBST-32, PBST-35, P-22, P-22 B1 phages는 narrow host range를 보였다. 숙주인 STWT, STKCCM, STCIP에 대한 phage 의 흡착률은 각각 47-85%, 58-95%, 61-93%였지만, STCCARM 에 대한 phage의 흡착률은 14-36%의 낮은 수준을 보였다. STWT, STKCCM, STCIP, STCCARM에 대한 phage burst size는 각 각 43-350, 37-530, 66-500, 24-500 plaque-forming unit (PFU)으로 다양하게 관찰되었다. P-22 B1을 제외한 모든 phage는 배양 초기에 STCIP숙주를 효과적으로 저해하였다. 이러한 결과는 항생제 내성균을 저해하기 위해 phage control system 개발에 유용한 정보로 활용될 것이다.

We determine the observing sites for eclipses of large magnitude recorded in ancient Chinese chronicles from 200 BCE to 900 CE, by adopting the difference between terrestrial time and universal time, ΔT, given by Morrison & Stephenson (2004). The records of solar eclipses with large magnitude are divided into four groups in accordance with the historical variations of the capital cities of ancient Chinese dynasties. We determine areas in which all the eclipses in each group, with an eclipse magnitude larger than a certain threshold value, could be observed. We find that these areas coincide with the historical capitals, which agrees with the general idea that the solar eclipses were observed at the capital of each dynasty. This result also veries the ΔT values during the period from 100 BCE to 400 CE, during which historical records of eclipses are so rare that the ΔT values can only be obtained by interpolating the long-term data. Moreover, we show that the eclipses described by the term Ji in East-Asian history are not all total eclipses; their mean magnitude is 0:96 ± 0:04. We find that complementary expressions, such as dark daytime and appearance of stars during the eclipse, strengthen the possibility that eclipses described by the term Ji were total. We also provide quantitative definitions for expressions such as `being not complete and like a hook', `being almost complete', `visibility of stars during the eclipse', and `darkness during an eclipse.' The literal meanings of these expressions are in agreement with the recent physical modeling of sky brightness during total eclipses provided by K¨onnen & Hinz (2008).

We report a massive outbreak of human Q fever cases, which occurred at totally 11 humans. The occurrence was related to a goat farm where Coxiella burnetii infection was diagnosed from goat tissues and environmental specimens. From January of 2018, continuous abortions from 6 goats occurred. Laboratory tests from 77 goat specimens for C. burnetii showed that 54 (70.1%) and 63 (81.8%) goats were positive by polymerase chain reaction (PCR) and enzyme-linked immunosorbent assay (ELISA), respectively. The infection was also confirmed from the farmer, his wife and 9 persons from all 16 veterinary officials who had visited the farm for protective measures and preparing goat specimens for laboratory tests. The farm was found to be extensively contaminated with C. burnetii from the examination to the environmental specimens and epidemiological inspections, which might be the main source of C. burnetii infection to humans. The extensive contamination to the farm was derived from the uncareful handling of postpartum animal tissues or discharges by the farm owner. This report will contribute to the establishment of educational system on the biosecurity to novice farmers.

Background: Forward head posture (FHP) is common postural malalignment. FHP is described relatively extension to upper cervical and lower cervical is relatively flexion. Although several researchers mentioned the lower cervical flexion posture in FHP, most of the studies related to FHP is focused on the deep cervical flexor function. Objects: The purposes of present study is to compare the cervical strength (upper cervical extension [UCE], lower cervical extension [LCE], upper cervical flexion [UCF], lower cervical flexion [LCF]) between individuals with and without FHP. Methods: Fifty-one participants are recruited. Participants who have the craniovertebral angle (CVA) less than 48 degree were classified to the FHP group (n = 24) and the others were included in without FHP group (n = 27). The cervical strength (UCE, LCE, UCF, LCF) were measured using Smart KEMA strength sensor and the strength data was normalized by body weight. All strength measurement conducted at head and neck neutral position in sitting. Independent t-test was used to compare the cervical strength between individuals with and without FHP. Results: The mean value of CVA was greater in without FHP group than with FHP group (p < 0.000). The strength value of UCF (p < 0.002) and LCE (p < 0.001) was significant less in FHP group than without FHP group. But no significant differences were seen in the LCF and UCE strength between two groups. Conclusion: UCF and LCE weakness in FHP group should be considered to evaluate and manage the individuals with FHP.

Site characterization for decommissioning Kori Unit 1 is ongoing in South Korea after 40 years of successful operation. Kori Unit 1’s containment building is assumed to be mostly radioactively contaminated, and therefore radiation exposure management and detailed contamination investigation are required for decommissioning and dismantling it safely. In this study, site-specific Derived Concentration Guideline Levels (DCGLs) were derived using the residual radioactivity risk evaluation tool, RESRAD-BUILD code. A conceptual model of containment building for Kori Unit 1 was set up and limited occupational worker building inspection scenario was applied. Depending on the source location, the maximum contribution source and exposure pathway of each radionuclide were analyzed. The contribution of radionuclides to dose and exposure pathways, by source location, is expected to serve as basic data in the assessment criteria of survey areas and classification of impact areas during further decommissioning and decontamination of sites.

The present study investigated the participation of D-serine and NR2 in antinociception produced by blockade of central erythropoietin-producing hepatocellular carcinoma (Eph) A4 (EphA4) signaling in rats with trigeminal neuropathic pain. Trigeminal neuropathic pain was modeled in male Sprague-Dawley rats using mal-positioned dental implants. The left mandibular second molar was extracted under anesthesia, and a miniature dental implant was placed to induce injury to the inferior alveolar nerve. Our current findings showed that nerve injury induced by malpositioned dental implants significantly produced mechanical allodynia; additionally, the inferior alveolar nerve injury increased the expression of D-serine and NR2 subunits in the ipsilateral medullary dorsal horn (trigeminal subnucleus caudalis). Intracisternal administration of EphA4-Fc, an EphA4 inhibitor, inhibited nerve injury-induced mechanical allodynia and upregulated the expression of D-serine and NR2 subunits. Moreover, intracisternal administration of D-amino acids oxidase, a D-serine inhibitor, inhibited trigeminal mechanical allodynia. These results show that D-serine and NR2 subunit pathways participate in central EphA4 signaling after an inferior alveolar nerve injury. Therefore, blockade of D-serine and NR2 subunit pathways in central EphA4 signaling provides a new therapeutic target for the treatment of trigeminal neuropathic pain.

이 연구는 위선의 실재와 그것이 우리의 ‘좋은 삶’에 대한 끊임없는 갈망과 갖는 연관성을 알아보고자 다음과 같은 세 가지 질문을 중심으로 다룬다: ‘위선 이란 무엇인가?,’ ‘위선과 연관된 문제에는 어떤 것들이 있는가?,’ 그리고 ‘위선 의 해결책은 무엇이며 어떻게 그것을 이룰 수 있는가?.’ 첫째로 최근 대중 문화 속 슈퍼히어로에 대한 관심이 급증한 사회적 현상의 맥락에서 덕과 위선의 언어가 우리의 현재 사회에 어떻게 위치해 있는지 알아본다. 둘째로, 플래너리 오코너의 두 작품을 통해 ‘위선적이지 않은 사람은 없으므로 누구나가 은총을 필요로 한다’는 개념이 어떻게 내러티브에 드러나는지 살펴본다. 셋째로 위선자들의 공통적인 특징으로 자아로부터의 분리와 자기 이해의 부족을 제시하고, 문학 작품에서 자주 표현되는 것처럼 특히 지성인들과 종교인들이 그러한 특징에 취약한 원인을 알아본다. 마지막으로 위선의 해결책으로 자신의 불완전함을 드러낼 수 있는 용기를 제안하며 자신과의 관계를 회복하는 데 있어 타인들과의 관계가 필수적임을 주장한다. 이것은 곧, 진정한 자아는 그 존재의 갈림이 전적으로 타인에게 맡겨질 때 비로소 드러난다는 것이다.

본 연구는 항생제 내성 Salmonella Typhimurium CCARM 8009을 저해하기 위한 phage와 항생제 조합처리의 효과를 평가하였다. 디스크 확산법과 액체배지 희석법에 의해 phage와 항생제의 상승 저해효과를 측정하였고 배양을 통한 항생제 내성 유도를 평가하였다. Phage를 처리한 cefotaxime, chloramphenicol, ciprofloxacin, erythromycin의 디스크의 저해 구역은 각각 13.6%, 19.3%, 12.7%, 78.8% 로 증가되었다. Phage와 항생제 조합 처리에 의해 tetracycline, chloramphenicol, ciprofloxacin, erythromycin, streptomycin의 최소생육억제농도는 각각 64, 4, 0.0078, 64, 256 mg/mL으로 감소되었다. Phage와 항생제의 조합 처리는 항생제 내성 S. Typhimurium CCARM 8009을 효과적으로 저해하였다 (4 log reduction). 본 결과는 phage와 항생제의 조합처리는 항생제 내성균을 제어하기 위한 방법으로 충분히 응용가치가 높음을 보여주고 있다.