PURPOSES : A mechanistic-empirical (ME) predictive design logic that can compute the reflective cracking life of hot-mix asphalt (HMA) overlaid on top of a composite pavement is proposed herein. METHODS : The overlay thickness design and analysis logic of the HMA were formulated based on the ME concept of reflection crack propagation. Climate data, traffic load data, the pavement material properties, and the thickness of each layer of the pavement are the main inputs for the ME-Reflective Cracking Rate (RCR) prediction algorithm. An Microsoft Excel Virtual Basic for Application (VBA) program was created to aid designers in assessing the expected performance of an HMA overlay design. Calibration was done using data from the Long-Term Pavement Performance (LTPP) sections. Sensitivity analysis was conducted to compare the results yielded by the program and data from a report by the Texas Transportation Institute. RESULTS : The predictive model performance effectively generates the dynamic and relaxation modulus curves. The correlation value of the calibration factors, R2, is 0.79. The calibration factors used for the Asphalt Overlay Thickness Design (AOTD) program and the sensitivity analysis, i.e., k1, k2,, and k3,, are set to 5, 5, and 150, respectively. The sensitivity of the AOTD program affords reasonable results. Additionally, the program yields results similar to the trends presented in a report by the Federal Highway Administration. CONCLUSIONS : The proposed ME design logic is successfully translated into an Excel VBA program, AOTD, which can perform routine assessments of laboratory tests for HMA overlays. The program can effectively perform numerous iterations and computations to predict an HMA overlay. The predictive model can generate reasonable dynamic modulus and relaxation modulus curves for the characterization of HMA overlays. Under the same asphalt binder grade and HMA type, doubling the HMA overlay thickness yields three times the expected reflective cracking service life.

최근 수십 년간 전 세계는 경제발전과 수송수단의 향상으로 다양한 외래종이 침입할 수 있는 시대가 되었다. 외국산 농산물의 수입요구는 외 래종의 침입을 보다 용이하게 하며 이렇게 침입한 외래종은 국내 생물상의 교란을 야기한다. 식물검역의 목적은 외래해충으로부터 국내 농업환경 및 생태계를 보호하는데 있다. 본 연구에서는 농림축산검역본부의 병해충정보시스템에 기록된 자료를 통해 1996년부터 2020년까지 수입절화류 에서 발견한 해충 검출 동향을 분석하였다. 이 기간동안 총 69개국 159품목 147,160개에서 검출된 해충은 13,757건의 467종 (잠정규제해충 273 종, 관리해충 78종, 비검역해충 118종)이었다. 특히, 총채벌레목과 매미목 해충의 검출율이 전체의 80% 이상을 차지하여 수입 절화류에서 가장 많 이 발견되는 해충분류군으로 분석하였다.

This research will examine how the Indonesian constitution can effectively protect the indigenous people’s rights to customary land when the land is under construction for infrastructure building. The authors will mainly discuss the relevance of justice for ensuring the rights to live and property of indigenous people under the Indonesian constitution. In this essay, the authors examine how constitutional and human rights protections interact with one another to ensure the security of customary land in Indonesia. The analysis will be carried out by two methodological approaches. One is the statute approach which is based on laws and regulations being specifically targeted. To implement the statutory approach, all Indonesian laws and regulations concerning the constitutional relationship and human rights to protect customary land will be reviewed. The other is the conceptual approach to identify the ideas that give rise to legal notions, the legal principles or legal arguments for solving the problem.

International terrorism has been a topical issue that caught the UN’s attention since the last quarter of the twentieth century. However, the UN initially dealt with it as an internal matter. In this regard, terrorism has become a global threat with the emergence of terrorist organizations. These organizations are not limited to a specific geographical scope; some of them are linked to countries, while others seek to occupy territories in order to control the oil wells and even create armies. They cannot continuously conduct their activities without financial support that provides it with the means to implement its plans and the resources to finance its field and logistical operations in all forms. One of the most important sources of financing terrorist and their organizations is money laundering operations. This research is to analyze the UN’s role in combating money laundering to prevent terrorist acts around the globe.

The home hydroponic system used in this experiment supplied the nutrient solution using the ebb and flow-type system, and the supply time, interval, and water levels of the nutrient solutions were fixed. This experiment was conducted to find a more favorable growth medium for plant growth in the hydroponic system. The medium used in the experiment was of two types, phenolic foam and rockwool, and the heights were 28 and 38 mm, respectively. As for the the multipurpose nutrient solutions (GNU1 and GNU2) were prepared in the lab. The composition of the GNU1 and GNU2 was the same, and there was a difference between 100 and 70% in ion concentrations. The plants used were Ssamchoo (Brassica lee ssp. namai) and Romaine lettuce (Lactuca sativa L. var. longiflora). First, in the physicochemical measurements of the empty medium, change in the pH and EC of the distilled water passing through the medium was less in the rockwool than in the phenolic foam. This indicates that there is less change in the chemical properties of the nutrient solution due to the medium when rockwool is used. After hydroponic culture of Ssamchoo and Romaine lettuce, the medium showed more residual salts in Romaine lettuce. Both Ssamchoo and Romaine lettuce showed less salt accumulation in rockwool. The emergence rate was significantly higher in rockwool for both species. The lower height of the medium, the faster the emergence was. Ssamchoo displayed significantly higher fresh weight (124.7%), shoot length (107.6%), and leaf width (107.9%) when grown in GNU1, but there were no significant differences as affected by the medium. However, in Romaine lettuce, the type and height of the medium resulted in significant differences. The fresh weight of Romaine lettuce was significantly higher in rockwool (119.6%) than in phenolic foam, and significantly higher at 38 (114.6%) than 28 mm. Although there is a difference depending on the species, rockwool is more suitable for the ebb and flow-type system than phenolic foam, and the height of 38 is more advantageous than 28 mm.

Few studies have been performed on ZrB2- graphite platelet composite made by spark plasma sintering (SPS) technique. In this research, the influence of adding graphite platelets (Gp) with and without SiC on the fracture toughness of ZrB2 ceramic was studied. The ZrB2- 10Gp, ZrB2- 15Gp, ZrB2- 30SiC-10Gp, and ZrB2- 30SiC-15Gp specimens were sintered by the SPS method at the temperature of 1850 °C for 8 min. The fracture toughness and work of fracture (WOF) were evaluated using the Single-Edge Notched Beam (SENB) technique. It was found that the fracture toughness and WOF were improved by the alone and combined addition of Gp and SiC to the monolithic ZrB2. The maximum fracture toughness of 4.8 ± 0.1 MPa m1/ 2 was obtained for the ZrB2- 15Gp specimen. It seems that adding Gp alone was more effective in enhancing the fracture toughness of ZrB2 than the combined addition of Gp and SiC. While the addition of Gp and SiC simultaneously modified the densification behavior to reach full-densified samples.

Alzheimer's disease (AD) is one of the most common forms of dementia, affecting more than 50 million people globally. The onset of AD is linked to age, smoking, obesity, hypercholesterolemia, physical inactivity, depression, gender, and genetics of an individual. The accumulation of Aβ peptides and neurofibrillary tangles (NFTs) in the brain is one of the critical factors that lead to AD, which is known to disrupt neuronal signaling and causing neurodegeneration. As per the current understanding, inhibiting the accumulation of Aβ peptides and NFTs is crucial in the management/treatment of AD. Latest research studies show that nanoparticles have the potency of improving drug transport across the blood–brain barrier easily. Specifically, graphene quantum dots (GQDs), a type of semiconducting nanoparticles, have been established as effective inhibitors for blocking the aggregation of Aβ peptides. The small size of GQDs allows them to pass through the blood– brain barrier with ease. Moreover, GQDs have fluorescence properties, which can be used to detect the concentration of Aβ in vivo. In recent years, compared to other carbon materials, the low cytotoxicity and high biocompatibility of GQDs, give them an advantage in the suitability and clinical research for AD. In this manuscript, we have discussed the role of different types of nanoparticles in the transportation of encapsulated or co-assembled compound drugs for the treatment of AD and importantly, the role of GQDs in the diagnosis and management/treatment of AD.

한국 천일염 생산 지역의 인구는 빠르게 고령화되고 있어 생산 노동자가 줄고 있는 추세이다. 소금 포집 작업은 천일염 생산 과정에서 가장 많은 노동력을 필요로 한다. 기존의 포집 장치는 사람의 작동 및 운전이 필요하여 상당한 노동력이 필요해서, 천일염 무인 포집장치를 개발하여 생산 노동자의 노동력을 감소시키고자 한다. 천일염 포집장치는 색상 검출을 통해 소금의 포집 상황과 염전에서의 위치를 파악하도록 설계되었기 때문에, 포집장치의 색상 검출 성능이 중요한 요소이다. 그래서 색상 검출 성능 향상을 위해 이미지 처리 를 이용한 알고리즘을 연구하였다. 알고리즘은 입력 이미지를 크기 재조정, 회전 및 투시 변환을 이용하여 around-view 이미지를 생성하고, RoI를 설정하여 해당 영역만 HSV 색상 모델로 변환하고 논리곱 연산을 통해 색상 영역을 검출한다. 검출 된 색상영역은 형태학적 연산을 이용하여 검출 영역을 확장하고 노이즈를 제거하여 컨투어와 이미지 모멘트를 이용하여 검출영역의 면적을 계산하고 설정된 면적과 비 교하여 염판에서 포집장치의 위치 경우를 결정한다. 성능 평가는 알고리즘을 적용한 최종 검출 색상의 계산 면적과 알고리즘의 각 단계 의 검출 색상의 면적을 비교하여 평가하였다. 평가 결과 소금을 검출하는 흰색의 경우 최소 25%에서 최대 99% 이상, 빨간색의 경우 최소 44%에서 최대 68%, 파란색과 녹색은 평균적으로 각각 7%와 15% 검출면적 증가가 있어 색상 검출 성능이 향상되었음을 확인할 수 있었으 며, 이를 무인 천일염 포집장치의 무인작업 수행을 위한 위치 확인에 적용 가능할 것으로 사료된다.

Chronic fibroinflammatory pancreatitis causes irreparable damage to the pancreatic parenchyma. This frequently results in food restrictions, painkiller addiction, and serious quality of life impairment in children. We observed a 13-year-old girl who had previously been hospitalized multiple times and had undergone acute pancreatitis arrived with excruciating abdominal pain and recurrent hematemesis. A chronic intra-pseudocyst bleed and an ampulla of Vater hemorrhage were discovered during an upper gastrointestinal endoscopy. A 3×2×1 cm pancreatic head pseudocyst was discovered on the magnetic resonance cholangiopancreatography, however the computed tomography scan revealed a pancreatic head pseudocyst, pancreatic duct stones, and substantial peripancreatic inflammation. The multidisciplinary team determined that Frey’s surgery was the most efficient method to minimize her suffering. No complications occurred during the healing phase following surgery, and two years later, neither recurrence bleeding nor abdominal pain appeared. In summary, Frey’s method is a secure and efficient intervention when applied by a multidisciplinary team.