Genetic factors are increasingly found as potential causes of children with acute recurrent pancreatitis (ARP) or chronic pancreatitis (CP). Representative genes include cationic trypsinogen, serine protease 1 (PRSS1), serine protease inhibitor Kazal type 1 (SPINK1), cystic fibrosis transmembrane conductance regulator (CFTR), chymotrypsin C (CTRC) and calcium sensing receptor (CASR) genes, etc. In Korean children, PRSS1 and SPINK1 genes have been most commonly studied, while CFTR mutations were reported in one patient to date. We report a case of a 13-year-old male adolescent with CP with CFTR mutations. Since he was first diagnosed with idiopathic acute pancreatitis (IAP) based on laboratory and computed tomographic findings, he was admitted with ARP and CP over four times in a year at the secondary and tertiary hospital. No etiology was detected by several examinations including magnetic resonance cholangiopancreatography (MRCP), endosco-pic retrograde cholangiopancreatography (ERCP), endoscopic ultrasonography (EUS) with fine needle aspiration (FNA) biopsy and genetic test including PRSS1 and SPINK1. Although he had no typical symptoms associated with cystic fibrosis (CF), CFTR mutations were detected with additional gene examination. Testing for CFTR mutations should be concerned in pediatric patients with APR and CP without other identified causes.

There are reports that inhaling hypertonic saline with bronchodilator is helpful in the treatment of bronchiolitis. However, further studies are needed to determine if it is helpful to inhale hypertonic saline with bronchodilator in children with recurrent wheezing. We aimed to investigate the effect of hypertonic saline inhalation in children with recurrent wheezing. A total of 40 patients under 6 years of age admitted to Kwangju Christian Hospital from December 2014 to May 2016 were enrolled. Patients were randomly assigned to receive salbutamol. In the control group (n=21), salbutamol (2.5-5 mg / 0.5-1 mL) was inhaled four times a day with physiological saline (0.9% normal saline 1-3 mL). In the experimental group (n=19), the same amount of hypertonic saline (5% saline 1-3 mL) was inhaled four times a day instead of physiological saline. We compared the duration of wheezing remission between patients who had recurrent wheezing (n=40). There was no difference in the duration of wheezing remission in patients who had recurrent wheezing. But the hypertonic saline inhalation group had a lower post treatment clinical score on the 2nd-3rd day of admission than the physiological saline inhalation group. In this study, hypertonic saline inhalation therapy was not significantly effective in the treatment of recurrent wheezing. More additional research is needed to determine whether inhaled hypertonic saline is effective in the treatment of recurrent wheezing.

Concrete made with ground granulated blast-furnace slag(GGBS) has many advantage, including improved durability, workability and economic benefits. GGBS concrete is that its strength development is considerably slower under standard 20°C curing conditions than that of portland cement concrete, although the ultimate strength is higher for same water-binder ratio. GGBS is not therefore used in application where high early age strength is required. In this study, to overcome the limitation of the initial strength decrease due to the use of slag, the slag substitution rate was changed to 30% under the low temperature curing temperature condition and the slag used concrete composition with the same or higher strength performance as OPC(Ordinary Portland Cement).

This study aimed to identify the respiratory viral etiology and clinical features in febrile neonates and young infants younger than 3 months of age. From June 2015 to March 2016, 126 patients who admitted to the pediatrics department of Kwangju Christian Hospital due to febrile illness (body temperature ≥ 38.0℃) without definite focus of fever. We tested nasopharyngeal aspiration specimens with real time reverse transcriptase polymerase chain reaction. Respiratory viruses identified in 66 patients, and not identified in 60 patients. Among identified viruses, the most common pathogen was rhinovirus. Respiratory virus identified patients showed significantly higher presence of sibling (p=0.015), sibling who attending day care center (p=0.022), respiratory symptoms of family members (p=0.022), concomitant respiratory symptoms of the patient (p=0.001).

This study aimed to identify initial predictive factors of meningitis among the febrile neonates. Retrospective analysis was conducted on the clinical data of 147 cases who admitted the neonatal intensive care unit due to fever (temperature ≥ 38.0 ℃) from 2010 to 2014. Lumbar puncture was performed on every case before administration of antibiotics. 37 cases (25.2%) were diagnosed as meningitis, who included 7 cases of bacterial meningitis (4.8%). When we compared meningitis group with non-meningitis group (110 patients), moaning was statistically higher in meningitis group. In a comparison of bacterial meningitis with aseptic meningitis (30 patients), grunting, fever peak on admission day and C-reactive protein were significantly higher in bacterial meningitis group.

When fresh concrete is exposed to extremely low temperature, the free water in the concrete transforms into ice, which causes decrease in compressive strength of concrete. For estimating the frost damage of the conrete structure, we use ultrasonic velocity method and estimate the compressive strength.

The aim of this study is to suggest the social vulnerability index for reflecting social properties of a region, such as population and economy, in vulnerability assessment. For such a research objective, this study composed the assessment index with 'social vulnerability' and 'physical vulnerability'. Also, this study composed the social vulnerability with 'population vulnerability index', 'economic vulnerability index' and 'information vulnerability index' while composing the physical vulnerability with 'flood-risk index', and then selected proxy variables. In addition, this study determined the weight using an entropy weight measurement as an objective weight measurement. The vulnerability assessment result is as follows: First, the vulnerable areas were concentrated around the inner harbours and some rivers of Incheon. Second, the areas vulnerable to the flood caused by climate change were found to be highly vulnerable socially as well as physically. Third, results of assessment were different according to the social properties of an areas despite the identical level of flood risk. The resultant implications are following. First, there is the necessity of having to put emphasis on social vulnerability of an area from the perspective of adaptation to climate change. Second, there is the necessity of having to arrange effective social and physical adaptation strategy based on the results of vulnerability assessment.

Recently, the environmental issues are emerging as one the most Compressive strength of concrete using blast furnace slag is decreased when cured at low temperature. To apply slag concrete in winter, we perform the experiment about alkali-activated slag concrete cured at low temperature.

Enterobius vermicularis is one of the most common parasites in the world and the infection rate is higher in children than adults. Although the most common clinical manifestation is perianal pruritus, it may cause other gastrointestinal manifestations. We report one case of appendicitis caused by Enterobius vermicularis. The clinical difference between typical appendicitis and the appendicitis due to Enterobius vermicularis is unclear. The patient had a repetitive Enterobius vermicularis infection for a past year, which was treated with occasional vermicides only. It is considered that the appendicitis is developed from the intractable Enterobius vermicularis infection.

The intussusception recurs in approximately 10 percent of children after successful nonoperative reduction. The main objective was to determine the clinical and sonographic findings that could be used to predict recurrence of ileocolic intussusception in children that had been successfully reduced by enema. A retrospective search was performed on 66 children, at age of 3 months to 7 years, with successful enema reduction of intussusception during a 2.5-year period from January 2013 to July 2015. The clinical, laboratory records, and sonographic findings were compared between recurrence of intussusceptions group (ROI) and non-recurrence group (NROI). Statistical significances were found in age (median, 26.0 vs 18.5 months; P =0.022) and terminal ileal wall thickening (mean, 10.23 vs 7.8 mm; p=0.002); in contrast, there was no significance considering gender, irritability (p=0.074), currant jelly stool (p=1.0), or C-reactive protein (p=0.908). Recurrence is associated with age and the thickening of terminal ileal wall, but clinical or laboratory findings. Given the small number of cases, further studies should be conducted.

The present study aimed to identify the factors that can clinically predict responses to macrolides treatment in patients with Mycoplasma pneumoniae pneumonia. Of the patients admitted to the pediatrics department of Kwangju Christian Hospital during December 2012 to March 2015, 195 patients who had pneumonia according to findings of chest radiography, positive Mycoplasma IgM, and fever at the time of admission were selected as study subjects. Patients were divided into one group wherein the duration of fever after macrolides treatment was 3 days or less and another group wherein the duration of fever was 4 days or more (169 patients [86.7%] vs 26 patients [13.3%]). In the group with fever duration of 4 days or more, a greater number of patients had a history of atopic dermatitis (3.6% vs 15.4%, p=0.11), and the symptom duration before admission was longer (cough: 4.04 days vs 6.38 days, p<0.001; fever: 3.96 days vs 6.08 days, p<0.001). Moreover, according to laboratory test results in the group with fever duration of 4 days or more, LDH levels were high (648.16 IU/L vs 829.92 IU/L, p=0.001), and there was a significant correlation between LDH levels and the duration of fever after macrolides treatment.

본 연구에서는 농업용 소규모 저수지의 붕괴에 따른 침수 지역 모의를 수문·수리 모형을 활용하여 산정하였다. 2014년 8월 21일에 발생한 집중호우로 경상북도 영천의 농업용 소규모 저수지인 괴연저수지가 붕괴하였으며, 그에 따라 저수지 하류부의 농가 및 농경지에 침수에 의한 피해가 발생하였다. 그러나 이러한 소규모 저수지는 유입량·방류량·수위·저수량 등 기본적인 수문학적인 요소를 측정하고 있지 않기 때문에, 무인비행기로 관측한 항공영상(DSM, Digital Surface Model)과 GIS(Geographic Information System)기법을 활용하여 저수지 내용적곡선 및 하류부 하천 형상을 추출하였다. 일반적인 수면아래의 지형고도는 항공영상으로 촬영할 수 없으므로 저수지 붕괴이후에 드러난 지형을 촬영하였으며, 각 지형고도별 격자를 GIS기법으로 계산하였다. 또한 하류부 하천의 지형고도 및 침수흔적도를 활용하여 침수모델링 및 모의결과 검증을 실시하였다. 그 결과 침수흔적도와 모델링 결과가 약 90% 정도 일치하는 결과를 나타내었으며 침수면적은 약 1.7 ha, 하천을 제외한 범람지역에서는 약 0.5 m 정도(성인 무릎높이)의 침수심이 산정되었다. 본 연구에서는 HEC-HMS 모형의 홍수량 산정시 실측자료를 통한 검·보정이 불가능 하였으므로, 향후 중소규모의 농업용 저수지에서도 활용할 수 있는 실측자료가 존재하고, 이를 적극 활용한다면 더욱 신뢰있는 결과를 도출해 낼 수 있을 것이다.

본 연구에서는 근적외 분광법을 이용하여 양념용 채소로 많이 사용되는 파, 마늘, 양파의 건조 불균일성을 관찰하였다. 대류식 온풍건조기에서 건조 위치에 따른 양념채소류의 건조 상태 차이를 조사한 결과, 건조 트레이의 높이나 위치에 따라 바람의 온도와 습도에 차이가 발생하여 건조가 균일하게 되지 않았다. 건조 정도가 다른 양념채소류의 2차 미분 근적외 스펙트럼을 비교한 결과 1,390 nm에서 1,400 nm 부근의 수소결합이 약한 물이 먼저 증발되었고 1,420 nm 부근의 수소결합이 강한 물은 건조 후에도 잔존함을 관찰할 수 있었다. 초분광 NIR 이미징 기법으로 측정한 스펙트럼을 주성분분석함으로써 건조채소의 건조도를 가시적으로 판별할 수 있었다.

최근에 건설분야 RC구조물의 시공도중 및 완공 이후에 이산화탄소 및 염소이온 등의 외기환경 노출과 콘크리트자체의 열화로 구조물의 사용성 및 구조성능 저하를 초래할 수 있다. 재료 및 시공적 측면에서 콘크리트의 탄산화 및 균열과 철근부식을 억제하고 제어할 수 있는 다양한 기술과 연구결과가 개발되고 소개되고 있다. 본 특집기사에서는 RC구조물을 건설하는데 있어 콘크리트의 내외부적인 요인에 의해 발생될 수 있는 열화와 그에 대한 대책과 관련된 최근기술 및 공법을 소개함으로써 관련기술에 관심을 갖고 있는 실무자나 연구자에게 유용한 자료를 제공하고자 한다. 첫째로, 동절기에 시공되는 옥외노출 콘크리트 수평부재에 동결융해로 인한 사용성 및 내구성 저하의 발생원인과 저감방법을 조사하는 기술을, 두번째로, 해상에 건설되는 콘크리트 토목구조물의 염해로 인한 콘크리트 및 철근의 열화요인과 대책에 대해 케이슨 구조물의 시공사례소개와, 마지막으로, 콘크리트의 수축에 의한 균열문제를 해결하기 위해 개발된 원통거푸집을 이용한 팽창콘크리트의 구속팽창 시험방법에 대한 개요와 활용사례에 대해 소개한다. 향후, 콘크리트 구조물의 열화에 따른 보수 및 보강에 관련된 첨단기술을 다시 소개하는 장을 마련할 수 있었으면 합니다.

Reaction degree of ground granulated blast furnace slag(GGBFS) in cement paste was measured by water-binder ratio and GGBFS replacement ratio, curing temperature with ages using selective dissolution. In result of experimental, when water-binder ratio and curing temperature were high and replace ratio of GGBFS was low, reaction degree was estimated high.

엑스선 의료영상이 디지털 시스템으로 발전함에 따라 의료영상의 평가 방법 또한 디지털 시스템에 맞춰 새롭게 개선되었으며 그 중 MTF(Modulation Transfer Function) 측정법은 Fujita이론에 기초한 에지법으로 ISO에 규정되었다. 에지법의 기초인 Fujita이론은 MTF 측정을 위해 슬릿의 각도를 디지털 검출기의 픽셀 열에 대하여 1° ∼ 2° 기울여 영상을 획득한 후 LSF를 합성하는 것으로 샘플링 간격은 각도에 따라 크게는 1/54배, 작게는 1/28배 감소하게 된다. 본 연구에서 사용된 장비는 Simens사의 MAMMOMAT Inspiration으로 비정질 셀레늄(amorphous selenium) 기반의 0.085 × 0.085 mm2 의 픽셀 사이즈를 갖는 검출기를 이용하여 presampling MTF를 측정하였다. 측정 방법은 Fujita의 슬릿법와 동일한 방법인 와이어법를 이용하였으며 측정된 영상에서 얻은 픽셀값을 이용하여 엑셀에서 이산 푸리에 변환을 시행하였다. 실험 결과 Fujita이론 대비 약 3배 이상의 샘플링 간격(sampling interval)의 경우 해상도 평가 지수인 10% MTF에서 약 85% 이하의 정확도를 보였으며 선예도 평가 지수인 50% MTF에서 약 93% 이하의 정확도를 나타내었다. 하지만 샘플링 간격이 Fujita 이론 대비 2배 정도 늘어난 경우는 50%와 10% MTF 모두 96% 이상의 정확도를 가진다는 것을 알 수 있었다.

영상 워핑은 입력 영상을 주어진 조건에 적합하게 변형하는 기술로, 최근 영화나 애니메이션 분야에서 캐릭터의 얼굴 형상을 변형하는데 활용되고 있다. 얼굴 특징을 기반으로 형상을 변형하는 워핑 방법 가운데 하나인 메쉬 워핑은 입력 영상에서 눈, 코, 입 주변의 사각형 모양의 메쉬 그룹을 형성하여 1:1정합시킴으로써 워핑 영상을 생성하는 방법이다. 이는 메쉬 제어점 좌표에 오차가 있거나 작은 면적의 메쉬로 세분화되어 생성된 경우 메쉬들의 경계 선분에서 결과 영상이 일그러지는 문제점이 있다. 본 연구는 얼굴의 자연스러운 워핑 영상을 생성하는 과정에서 오류 발생을 최소로 하며 정확한 결과를 적은 연산량과 시간에 처리하기 위해 삼각형기반의 영상 보간 기법을 제안한다. 우선 얼굴을 대표하는 특징점들을 찾고 이들을 연결하여 기본 삼각형 메쉬를 구성한다. 제안하는 방법은 기존의 메쉬 워핑과 비교하여 연산 처리량과 시간은 단축되면서 워핑 과정에서의 오류 발생을 줄일 수 있음을 실험으로 보인다.