This study evaluates the gastroprotective effect of cabbage extract with sulforaphane content of 5.19 mg/L and Smethylmethionine content of 469.28 μg/L. In vitro, the lipopolysaccharide (LPS)-treated group had an increased NO activity compared to the normal group, and the concentration of NO was reduced when the cabbage extract was treated in the dose manner. The level of IL-6 induced by LPS was dose-dependently reduced when the extract was treated. The cabbage extract concentration was orally administered in rats at 5.75 mg/kg, 11.5 mg/kg, and 23 mg/ kg, and the inhibitory effect on gastric damage by HCl-ethanol was observed. Histological analysis exhibited mucosal erosion in the gastritis model compared to the normal group, while the ameliorating effect of the generated erosion was observed in the cabbage-treated group. The histamine concentration was significantly increased in the gastritis-induced animal model, and the histamine concentration was decreased in the 23 mg/L-treated group of cabbage extract. In conclusion, the results of this study suggest that cabbage extract not only down-regulates cytokines in vitro, but is also directly involved in histamine secretion in an animal model of gastritis; therefore, cabbage extract can help inhibit gastrointestinal disorders by improving the protective barrier.

The immunological sperm separation method is economical compared to the existing sorting method, and it is promising for the development of new technologies by reducing sperm damage. Wholemom (WM) is a sex-regulating protein that comprises on immunoglobulin G coupled with magnetic nanoparticles (MNPs) that responds to surface proteins derived from the Y chromosome in cattle. Y sperms are restricted in motility as the WM aggregates them, and the magnet could separate the non-aggregated cells. This study was conducted to investigate the effect of WM treatment on the characteristics of bull sperm. After treating sperm with WM and incubation for 6 h, the motility parameters including total motility, progressive motility, velocity average path, velocity straight line, amplitude of lateral head displacement, and linearity were significantly higher in the WM treatment group than in the control group (p < 0.05). Sperm viability and acrosome reaction rates were similar in both groups during each incubation period (p > 0.05). In conclusion, the immunological sperm sexing procedure using a monoclonal antibody conjugated with MNPs did not affect the characteristics of bull sperm. This study suggests that compared to other techniques, the immunological method for sperm sexing could classify sperm quickly and efficiently without the use of expensive equipment.

Trading card game은 사용자들이 카드를 수집하고 교환하면서 게임을 진행한다. 사용자는 카드별로 존재하 는 특수 능력과 필요 비용 등을 고려하여 카드를 수집한다. 한정판 카드는 카드에 희소가치를 부여하여 사용 자들의 수집욕을 자극하여 구매를 유도할 수 있다. 기존 Trading card game인 Slay the Spire나 Hearths Sto ne는 초기 덱 빌딩할 때, 사용자의 능력보다는 운이 영향을 끼친다. 카드 구성을 변경하는 것이 쉽지 않으므 로, 초기 덱 빌딩 결과가 게임의 승패에 결정적인 영향을 주기도 한다. 반면에, Legends of Runeterra는 게임 의 규칙이 너무 복잡해서, 초보자들이 게임을 어렵다고 느낀다. 이러한 점을 고려하여, 제안하는 게임 매직 파이트는 다음과 같은 특징이 있다. 초보자들도 쉽게 게임을 플레이할 수 있도록, 제안하는 게임은 덱 빌딩 방법을 단순하게 구성한다. 사용자들이 다양한 전략을 시도해 볼 수 있도록, 매 판마다 덱 구성을 변경할 수 있다. 실험결과 덱 빌딩시 카드의 종류를 일부 제한하면 상대적으로 카드 구성이 단순해서, 사용자가 카드의 효과와 이미지를 쉽기 이해하는 경향을 보인다. 반면에, 모든 종류의 카드를 대상으로 덱 빌딩을 하면, 사용 할 수 있는 카드의 수가 상대적으로 많으므로, 사용자가 다양한 전략을 시도해 볼 수 있어서 더 재미있었다 고 응답하였다.

In the era of the 4th industrial revolution driven by the convergence of ICT(information and communication technology) and manufacturing, research on smart factories is being actively conducted. In particular, the manufacturing industry prefers smart factories that autonomously connect and analyze data. For the efficient implementation of smart factories, it is essential to have an integrated production system that vertically integrates separately operated production equipment and heterogeneous S/W systems such as ERP, MES. In addition, it is necessary to double-verify production data by using automatic data collection technology so that the production process can be traced transparently. In this study, we want to show a case of data-centered integration of a large aircraft parts processing factory that requires high precision, takes a long time, and has the characteristics of processing large raw materials. For this, the components of the data-oriented integrated production system were identified and the connection structure between them was explained. And we would like to share the experience gained through the design and implementation case. The integrated production system proposed in this study integrates internal components based on data, which is expected to serve as a basis for SMEs to develop into an advanced stage, and traces materials with RFID technology.