목적 : ‘치매관리법’에 따라 전국적으로 치매안심센터가 설립되고, 치매 관련 서비스를 제공할 수 있는 전문 인력의 요구도 증가되고 있다. 하지만 치매안심센터 조기검진팀의 구성원으로 작업치료사는 배제되어 있다. 따라서 치매안심센터 조기검진팀 구성원으로서 작업치료사의 필요성과 중요성을 알아보고자 하며, 이에 근거 자료를 제시하고자 한다. 연구방법 : 치매 평가영역에서 작업치료사의 역할에 대한 문헌을 중심으로 고찰하였으며, 작업치료사가 시행하는 평가도구 및 평가영역에 대하여 국내 및 국외 연구, 보건복지부 치매정책 관련 자료집과 치매센터 책자를 통하여 자료를 수집하였다. 치매안심센터 조기검진팀에서 시행하는 선별검사 및 신경인지검사와 작업치료사가 주로 사용하는 인지관련 평가도구의 항목들을 분석하였다. 결과 : 작업치료 수행영역에서 인지ᆞ지각영역의 평가 및 치료는 중요도나 수행도 측면에서 상위에 위치한다. 치매안심센터의 평가와 작업치료사들이 임상에서 사용하는 평가는 6가지 인지영역(기억력, 시공간 능력, 집중력, 실행능력, 계산능력, 언어능력)에서 중복되어 사용되고 있다. 결론 : 본 연구에서 작업치료사는 인지ᆞ지각 평가 영역에서 충분한 자질을 갖추고 있는 전문가임을 제시 하였기에 치매안심센터 조기검진팀의 구성원으로 포함되어야 하는 근거자료가 될 것이다. 본 연구는 앞으로 보건복지부에 치매정책관련 개정사항으로 의견 제출 시 유용하게 활용 될 것이다.

Four-week repeated-dose toxicity of Misaengtang (MST) was evaluated according to Toxicity Test Guideline of Korea Food and Drug Administration using 6-week-old Sprague-Dawley rats. Based on the results of preliminary single-dose toxicity study, confirming safety up to an upper-limit dose, MST was dissolved in drinking water and orally administered at doses of 500, 1,000, or 2,000 mg/kg for 28 days. All doses including the upper-limit limited dose (2,000 mg/kg) of MST did not cause any abnormalities of rats, including mortality, clinical signs, body weight gain, feed/water consumption, necropsy findings, organ weights, hematology and blood biochemistry. Rather, high doses (1,000-2,000 mg/kg) of MST reduced the serum levels of alanine transaminase, aspartate transaminase, creatinine phosphokinase, lactate dehydrogenase and triglycerides, in addition to an increase in glucose, indicative of protective effects on hepatic and muscular injuries. Both maximum-tolerable dose and no-observed-adverse-effect level were not determined. The results indicate that long-term intake of high-dose MST might not induce general adverse-effects.

There has been much research on the reliability and durability of the product life cycle using accelerated life test(ALT), accelerated stress test(AST) and accelerated stress audit(ASA) in the industry. Most of these systems use vibration induced by acceleration and deceleration. The device used for these kinds of research should have wide-band exciting frequency ranges to find the weak mode of the product. In this paper, platform of ALT based on the Stewart platform is controlled by using pneumatic actuators. Pneumatic actuators use motion and impact in this paper to cause wide-band exciting frequency. The change in frequency and pressure in the six cylinders is used to control the level of exciting vibration. Many control strategies are tested to improve the performance and one of the best control algorithms is suggested.

Recently, there are many researches that are performed for increasing reliability about product life cycle using ALT(Accelerated Life Test), AST(Accelerated Stress Test) and ASA(Accelerated Stress Audit) in the industry. The test of this research needs a device that has wide-band frequency vibration. But most test devices such as HALT only show the good response of high frequency area. In this research, the platform of ALT was developed based on Stewart Platform using pneumatic Actuators. Pneumatic Actuators represent response of wide-band frequency by motion and mpact. Cylinders of Stewart Platform is operated based on frequency and pressure. This research shows system characteristic of Platform to develop the control algorithm of accelerated life test platform in future research.