본 연구는 아스팔트 혼합물에 사용되는 재료들을 산업부산물로 활용함으로써, 경제성 확보 및 공용성 능의 개선 효과를 확인하기 위한 것으로써, 천연골재를 대체하기 위해 제강공정에서 발생되는 전기로 산 화슬래그 골재를 분쇄, 선별하여 사용하였으며, 석회석 등의 채움재는 자동차유리를 분쇄 선별하여 사용 하였다. 아스팔트 바인더의 성능개선을 위하여 폐자동차의 폴리머 재료도 활용하였다. 실내시험 및 현장 적용 결과, 전기로 슬래그 골재의 일반적인 물성이 천연골재와 유사한 것으로 나타났으며, 폐유리를 이용 한 채움재 또한 석회석을 대체하는데 문제가 없을 것 판단된다. 표 1과 2는 각 재료별 물성시험결과로 관 련기준을 만족하는 것으로 나타났다. 또한 각 재료별 유해성을 평가하기 위한 중금속 용출 시험결과에서도 관련기준에 적합한 것으로 나타 났다. 표 3 및 표 4는 중금속 용출 실험결과이다. 각 재료를 이용하여 혼합물을 제작하고 실시한 물성시험결과 표 5에서와 같이 안정도가 천연골재를 활 용한 일반아스팔트 혼합물에 비해 우수한 것으로 나타나, 전기로 산화 골재 등을 활용하여 경제적이고 우 수한 품질의 생산 및 시공이 가능할 것으로 판단된다.

자동차의 경우 제조단계부터 폐기단계까지의 전 과정에 걸친 환경부하를 줄이기 위한 노력이 활발히 진 행되고 있다. 특히, 국내외 폐차 법규가 확정되면서 폐차의 친환경적인 처리를 위해 플라스틱, 고무재료 등 에 대한 재활용 실용화 기술에 많은 연구가 진행되고 있으며, 폐유리의 경우는 화학성분 중 70% 이상이 실리카(SiO2) 성분으로 시멘트와의 반응시 포졸란 작용 및 기타 충전재의 역할이 기대되기 때문에 폐유리 를 콘크리트 품질 개선을 위한 환경 친화적 혼화재로서 활용할 수 있는 방안에 대한 연구가 학계에서 일부 발표되었으나 현재 많이 사용되지 않고 있다. 따라서 본 연구에서는 자동차 폐부품인 폐유리의 재활용 방 안을 모색하기 위하여 폐유리 미분말을 결합재(Binder)의 10~30%를 치환하여 대체율에 따른 모르타르와 콘크리트의 기초물성 실험 수행과 폐유리 잔골재를 일반 세척사의 10~30% 치환한 콘크리트의 기초물성 실험을 통해 도로 소구조물 및 콘크리트포장 활용 가능성에 대한 기초자료를 제시하고자 한다. 본 연구의 실험방법은 폐유리 미분말의 모르타르의 물성 검토를 위해 모르타르 제조직후 플로우를 검 토하고 재령 7, 28일의 압축강도를 측정하였고, 콘크리트의 물성 검토를 위해 재령 7, 28일의 압축강도와 재령 28일에서의 염소이온침투저항성 시험을 수행하였다. 또한 폐유리 잔골재의 모르타르의 물성 검토를 위해 모르타르 제조직후 플로우를 검토하고 재령 3, 7, 28일의 압축강도를 측정하였다.

본 연구는 폐차 처리과정에서 발생하는 폐부품인 폐유리 및 폴리머 재료와 제강과정에서 발생하는 부산물 인 슬래그를 도로포장 재료로 활용하기 위해 수행하였으며, 기초연구를 통해 아스팔트 혼합물의 골재와 채 움재를 대체하고 아스팔트 바인더 성능의 개선을 위한 첨가제를 개발하여 현장에 적용하고 모니터링을 실시 하였다. 사용된 골재는 천연재료를 대체하기 위해 전기로 산화 슬래그 골재를 분쇄 선별하여 표 1과 같은 기 초물성 값을 얻었으며, 폐유리는 분쇄하여 표 2와 같이 채움재 사용기준의 적합여부를 확인하였다.

Ocean discharge of sewage sludge, which started in the year of 1993 in Korea, was stopped in the beginning of 2012, Landfill of sewage sludge was also prohibited in 2003 owing to public acceptance of the lanfill sites, and partially reopened in 2007 due to the necessity of organic component in sludge to produce methane gas. Sludge recycle ratio will increase in sewage sludge treatment by volume reduction and drying, and then recycle of the thermal energy as fuel in power plant and also material as raw material of cement. Several drying processes are compared with reasoning and an appropriate drying sequence is suggested.

Diamond-like carbon (DLC) films have been widely used in many industrial applications because of their outstanding mechanical and chemical properties like hardness, wear resistance, lubricous property, chemical stability, and uniformity of deposition. Also, DLC films coated on paper, polymer, and metal substrates have been extensively used. In this work, in order to improve the printing quality and plate wear of polymer printing plates, different deposition conditions were used for depositing DLC on the polymer printing plates using the Pulsed DC PECVD method. The deposition temperature of the DLC films was under 100˚C, in order to prevent the deformation of the polymer plates. The properties of each DLC coating on the polymer concave printing plate were analyzed by measuring properties such as the roughness, surface morphology, chemical bonding, hardness, plate wear resistance, contact angle, and printing quality of DLC films. From the results of the analysis of the properties of each of the different DLC deposition conditions, the deposition conditions of DLC + F and DLC + Si + F were found to have been successful at improving the printing quality and plate wear of polymer printing plates because the properties were improved compared to those of polymer concave printing plates.

고속도로에서 재령이 20년이 넘는 노후 콘크리트가 늘어남에 따라 콘크리트 포장의 보수/보강이 중요한 이슈로 대두되고 있다. 노후 콘크리트 포장의 보강 대안으로서 아스팔트 덧씌우기가 많이 사용되고 있으나 반사균열 및 포트홀 등 체류수로 인한 문제가 심각하게 대두되고 있다. 본 연구는 반사균열 및 체류수의 문제를 최소화하기 위해 고안된 접착식 방수층을 소개하였으며 포장가속시험을 통해 일반 택코팅을 적용한 합성단면포장과 비교평가를 실시하였다. 실험은 강우를 모사하기 위해 물을 뿌리면서 진행하였고 덧씌우기 포장체의 거동 및 수분 저항 특성을 분석하였다. 연구결과 접착식 방수층은 아스팔트 포장과 콘크리트 포장이 일체로 거동하는 것을 도와주기 때문에 아스팔트 포장체에 발생하는 거동이 일반 택코팅 구간과 완전히 다른 것으로 나타났다. 또 수분의 유입을 최소화하므로 결과적으로 반사균열의 발생을 약 70% 지연시키는 것으로 나타났으며, 체류수로 인한 손상도 줄여주는 것으로 나타났다.

본 논문은 에폭시 계열의 폴리머 콘크리트 교면포장 공법의 국내 적용 가능성을 검토하기 위하여 교면포장용 폴리설파이드 에폭시 재료에 대한 물리 역학적 특성을 평가하기 위하여 수행하였다. 강도특성을 평가하기 위하여 압축강도, 휨강도, 접착강도 시험을 수행하였으며 내구특성 평가를 위하여 염소이온침투시험, 동결융해저항성시험, 자외선영향 평가를 실시하였다. 시험결과 압축강도, 휨강도, 접착강도 등은 미국콘크리트협회에서 제시하는 기준을 만족하는 것으로 평가되었다. 그러나 다양한 시험온도에서의 강도 시험결과에서 에폭시 재료가 온도 의존성이 큰 것으로 나타나 향후 국내 적용시 이에 대한 고려가 필요할 것으로 판단된다. 휨강도 시험을 통한 처짐에 대한 추종성은 기존 아스팔트 교면포장에 비해 우수한 것으로 평가되었다. 또한 염소이온침투 저항성, 동결융해 저항성 등에 대해서도 우수한 성질을 가진 것으로 평가되었다. 에폭시 슬러리 혼합물에 대한 자외선 영향 평가에서는 강도 증가와 파괴시 변형률 감소가 나타났으나 자외선 노출 후에도 기존 아크릴계 폴리머 콘크리트보다 처짐에 대한 추종성이 양호한 것으로 평가되었다. 따라서 폴리설파이드 에폭시 재료가 교면포장 공법으로 사용하기에 적절한 물리적 특성을 가지고 있다고 판단된다.

Selenium (Se) obtained from dietary sources is an essential micronutrient for normal body function and it functions as an essential constituent of selenoproteins. We investigated the influence of Se on the formation of colonic aberrant crpyt foci (ACF) and tumor formation induced by azoxymethane (AOM) and dextran sodium sulfate (DSS) in male ICR mice. Five-week old ICR mice were acclimated for one week and fed on the low iron diet (LFe, 4.5 ppm) and different Se diet [Lse (0.02 ppm), Normal Se (0.1 ppm), HSe (0.5 ppm)] for 12 weeks. Animals received intraperitoneal injections of AOM (10㎎/㎏ B.W. in saline weekly for 3 weeks), followed by 2% DSS (molecular weight 36,000～50,000) in the drinking water for a week. There were five experimental groups, including a normal control group, AOM/DSS, LFe+AOM/DSS, LFe+AOM/DSS+LSe, LFe+AOM/DSS+HSe. After sacrifice of animals, the total numbers of AC and ACF were measured in the colonic mucosa. The number of mice bearing tumors was expressed as tumor incidence rate. The iron and selenium liver concentration was measured using ICP-AES. Glutathione peroxidase (GPx) activity was determined using a GPx assay kit in the liver and colon. TUNEL and proliferating cell nuclear antigen (PCNA) staining were performed to examine the cell apoptosis and cell proliferation. In addition, immunohistochemistry of β-catenin was also performed on the mucous membrane tissue of colon. In AOM/DSS-induced colon carcinogenesis animal model, LFe diet decreased the number of 2.95±2.5 ACF/cm2 to 1.85±1.1 ACF/cm2 but it increased the total number of 5.06±4.2 AC/cm2 to 6.19±4.8 AC/cm2 compared with normal iron diet. In the iron-deficient mice, selenium did not affect the either the number of ACF or AC. The tumor incidence rate was higher in LFe diet groups than in normal iron diet group and high selenium diet weakly reduced the tumor incidence. Low selenium diet decreased the activity of GPx in the liver and colon. Apoptotic positive cells were decreased in the low selenium diet group. In addition, on the β-catenin staining, positive cells were increased in the low selenium diet group while they were decreased in the high selenium diet group. These findings indicate that the dietary levels of selenium was not highly enough to exhibit a significant protection against colon carcinogenesis in the iron-deficient mice. However, our results also indicate that dietary selenium might exert a protecting effect against colon cancer by increasing GPx activity and apoptosis and by inhibiting cell proliferation and β-catenin over-expression.

Carnosine is a dipeptide (β-alanyl-L-histidine) found in mammalian brain, eye, olfactory bulb and skeletal muscle at high concentrations. Its biological functions include antioxidant and anti-glycation activities. The objectives of this study were to investigate anti-diabetic effects of carnosine as determined by blood glucose levels in glucose tolerance test (GTT) and insulin tolerance test (ITT), insulin level and serum biochemical and lipid levels in male C57BL/6J db/db mice. There were five experimental groups including normal (C57BL/6J), control (vehicle), and three groups of carnosine at doses of 6, 30, and 150 mg/kg b.w. Carnosine was orally administered to the diabetic mice everyday for 8 weeks. There was no significant difference in body weight changes in carnosine-treated groups compared to the control. The treatments of carnosine significantly decreased the blood glucose level in the diabetic mice compared with the control (p < 0.05) after 5 weeks. The treatments of carnosine also significantly decreased the blood glucose levels in GTT and ITT and glycosylated hemoglobin (HbA1c), compared with the control (p < 0.05). Carnosine at the dose of 6 mg/kg significantly decreased the serum insulin level compared to the control (p < 0.05). Carnosine significantly increased total proteins but significantly decreased lactate dehydrogenase and blood urea nitrogen compared with the control (p < 0.05). Carnosine also significantly decreased glucose, LDL, and triglyceride in the serum of diabetic mice compared to the control (p < 0.05). These results suggest that carnosine has a hypoglycermic effect resulting from reduction of glucose and lipid levels and that high carnosine-containing diets or drugs may give a benefit for controlling diabetes mellitus in humans.

The aim of this study was to examine the promoting effect of herbal extracts on hair regrowth in C3H/HeJ mice. The herbal extracts were obtained from the Damo-cosmetics Inc. There were four experimental groups including distilled water (D. W., negative control), 20% ethanol (EtOH, vehicle control), 3% minoxidil (MXD, positive control), and herbal extract (Ext). The herbal extract included the mixture of water and alcohol extract from Pleuropterus multflorus, Lonicera japonica Thunberg, Phellinus linteus, and Phaseolus radiatus. Test compounds were applied to the shaved dorsal skin of mice mouse for 3 weeks. The photograph of hair regrowth was taken at day 0, 4, 7, 10, 14, 17, and 21. The herbal extract group showed faster hair regrowth than negative control group or 20% EtOH groups after 10 and 14 days of treatments. The elongation of hair follicles in MXD and the herbal extract groups were observed. The activities of alkaline phosphatase (ALP) and γ-glutamyl transpeptidase were sfanificantly (γ-GT) increased in MXD and herbal extract groups compared with negative control group (p＜0.05). The expression of epidermal growth factor (EGF) and vascular endothelial growth factor (VEGF) were also sfanificantly hfaher in MXD and herbal extract group than negative control group (p＜0.05), althouah there were no sfanificant differences amoularhe groups of 20% EtOH, MXD, and herbal extract. These results suagest that the herbal extract used in this study may have grpromoting effect on hair regrowth by increasing activities of ALP and γ-GT and expression of EGF and VEGF.

Anti-wrinkle effect of herbal extracts was investigated on the skin of in a model of animal irradiated by ultraviolet rey B (UVB). The female albino hairless mice (HR/ICR) were randomly allocated to the normal control group (NC-non irradiated-vechicle), positive control group (PC, UVB irradiated vehicle) and herbal extract (HE) group. The herbal extract included the mixture of water and alcohol extract from Pleuropterus multflorus, Lonicera japonica Thunbert, Phellinus linteus, and Phaseolus radiatus. The herbal extract was treated dorsally with 0.2 ml per mouse five times a week for 12 weeks. At fifth week of the treatment, the animals were exposed to UVB irradiation for subsequent eight weeks three times a week. The intensity of irradiation was gradually increased from 30 mJ/㎠ to 240 mJ/㎠ (1MED: 60 mJ/㎠). Dorsal skins were obtained and stained with H&E to examine histological changes and epidermal/dermal thckness. The collagen fiber was also observed in Masson-Trichrome staining. Hydroxyproline assay and western blot analysis were also carried out to detect the change of collagen amount and to investigate MMP-1 expression, respectively. The HE group showed a better appearance and weak wrinkling, compared to PC group, The treatment of herbal extract significantly increased the thickness of dermis and the amount of collagen fibers compared to PC group (p＜0.05). The treatment of HE significantly increased the hydroxyproline amount compared to PC group (p＜0.05). The chronic UVB irradiation to hairless mice skin increased expression of MMP-1 but the treatment of HE decreased the expression of MMP-1. These results indicate that the herbal extract used in this study have a preventive effect on the UVB-induced wrinkle in a hairless mice model, partly due to the reduction of MMP-1 expression and increment of collagen amount.