본 논문의 주된 연구 목적은 우리나라 대도시의 지역-연령-특수적 인구이동 특성을 파악하는 것이다. 이를 위해 지역-연령- 특수적 인구이동 연구를 위한 방법론적 토대를 마련하고자 했는데, 지역-특수적 인구이동 연구를 위한 공간단위를 새롭게 규정하 고, 인구이동 플로의 연령 특화도 분석을 위해 플로 SSD를 활용하였다. 이러한 방법론적 토대 위에서 연구 절차를 정련화하여 우리나라 7대 특별･광역시의 2020년 인구이동 데이터에 대한 분석을 실시하였다. 주요 분석 결과는 다음과 같다. 첫째, 서울의 경우, 특화된 전출 플로는 모든 연령 그룹에서 골고루 나타나지만 연령 그룹 간에 공간적 분리가 현저하다. 특화된 전입 플로는 25~29세에 집중적으로 나타나며, 전출 플로에 비해 특화도도 높다. 둘째, 부산, 대구, 광주, 대전, 울산은 유사한 경향을 보여준다. 특화된 전출 플로는 25~29세에 지배적으로 나타나고, 35~39세에 가장 적다. 특화된 전입 플로 역시 25~29세에 지배적으로 나타난다. 25~29세에 특화된 전출 플로는 주로 수도권 지역에 집중되고, 65~69세는 주변의 시군 지역에 한정되는 경향이 있다. 연령 그룹별 특화 지역이 전입 플로와 전출 플로 사이에서 어느 정도의 공간적 일치성을 보이지만, 특화 플로의 수와 특화도는 전입 플로가 전출 플로에 비해 상대적으로 적고 낮다. 셋째, 인천은 다른 광역시와는 다른 특성을 보인다. 전출 플로와 전입 플로 모두에서 연령 그룹이 25~29세에 집중되지 않고 골고루 나타나는 경향이 있는데, 특히 35~39세의 비중이 상대적으로 높게 나타난다. 전입 플로와 전출 플로 사이에서 연령 그룹별 특화 지역의 공간적 일치성이 두드러지지 않는다. 향후에 방법론적 정련화와 보다 많은 지역 혹은 보다 많은 시점에 대한 실증적 분석이 이루어지길 기대한다. 주요어 : 지역-연령-특수적, 플로 표준화상이점수, 공간단위, 전출, 전입

본 논문의 주된 연구 목적은 우리나라 디지털 행정구역 경계 파일의 일반화를 위한 실행 원칙을 수립하고, 그것에 기반해 적절한 일반화가 적용된 주제도 제작용 기본도를 제시하는 것이다. 이론적인 수준에서 맥매스터와 셰이의 디지털 일반화 모형을 검토하였고, 알고리즘 수준에서는 더글라스-포이커 알고리즘과 비스발링엄-화이엇 알고리즘을 비교하였다. 일반화를 위한 알고리즘으로 원 데이터의 피처간 연접성이 보존되고, 단순화뿐만 아니라 완곡화도 일부 수행하는 수정 비스발링엄-화이엇 알고리즘이 채택되었다. 우리나라 2020년 6월 30일 기준의 읍면동 경계 파일을 대상으로 목표 축척을 1:4,000,000과 1:8,000,000으로 설정한 일반화를 수행하였다. 서로 다른 버텍스 보존율로 일반화한 여덟 장의 지도를 비교한 결과, 1:4,000,000 축척을 위해서는 버텍스 보존율이 0.2%인 지도, 1:8,000,000 축척을 위해서는 버텍스 보존율이 0.05%인 지도가 적절한 것으로 판단되었다. 본 연구는 상세성이 너무 높은 원본 행정구역 경계 파일이나, 원칙과 근거가 부족한 일반화가 적용된 경계 파일을 무비판적으로 사용하는 관행에서 벗어날 수 있는 최소한의 근거를 제시했고, 축척별 표준 행정구역 경계 파일의 세트를 구축하기 위한 보다 광범위한 기획의 시발점 역할을 했다는 의미에서 학술적･실질적 가치가 있다고 평가한다.

An ultra-high temperature ceramic, tantalum carbide, has received much attention for its favorable characteristics: a superior melting point and chemical compatibility with carbon and other carbides. One drawback is the high temperature erosion of carbon/carbon (C/C) composites. To address this drawback, we deposited TaC on C/C with silicon carbide as an intermediate layer. Prior to the TaC deposition, the TaCl5-C3H6-H2 system was thermodynamically analyzed with FactSage 6.2 and compared with the TaCl5-CH4-H2 system. The results confirmed that the TaCl5-C3H6-H2 system had a more realistic cost and deposition efficiency than TaCl5-CH4-H2. A dense and uniform TaC layer was successfully deposited under conditions of Ta/C = 0.5, 1200 oC and 100 torr. This study verified that the thermodynamic analysis is appropriate as a guide and prerequisite for carbide deposition.

Phosphoprotein Enriched in Astrocytes (PEA15) is a 15kD-sized intracellular signaling protein, highly expressed in astrocytes and constitutively expressed in peripheral tissues. Recently it was found that PEA15 expression was elevated in patients suffering type 2 diabetes and suggested to be involved in the syndrome of insulin resistance. To investigate the functional role of PEA15 for the control of blood glucose level, we produced a transgenic pig over-expressing mouse PEA15 (mPEA15). As a model animal, pig has many advantages. They have a higher fecundity and a short generation time and are physiologically similar to human. Using the transgenic pig, we carried out a series of experiments to establish a link between PEA15 expression and the insulin resistance. Our results suggested that, compared with control pig, mPEA15 pig has, (1) a higher blood resistin level, (2) a lower cell membrane-embeded GLUT4 level, and (3) a lower glucose clearing ability based on oral glucose tolerance test (OGTT). When our results combined, it can be concluded that mPEA15 over-expressing pig has many symptoms of insulin resistance and these pigs will become a useful disease model to investigate diabetes mellitus in the near future.

Unstable Epigenetic reprogramming was DNA methylation, imprinting, RNA silencing, co-valent modifications of histones and remodelling by other chromatin-associated complexes. After fusion with an enucleated oocyte, a differentiated somatic cell can restructure its genetic program and acquire totipotent characteristics. However, these cases happen only with low frequency. primordial germ cells (PGC) was effectively remove of epigenetic modifications in the genetic totipotency which is necessary for the development. The present study was in vitro development of reconstruct PGC NT embryos compared with somatic cell NT embryos. The rate of cleavage did not differ between NT embryos from PGC and somatic cells (87.26 vs 91.36%). However, the rate of development to the blastocyst stage was significantly higher in PGC cell NT than somatic cell NT (31.03 vs 19.27%). PGC from a slightly younger stage of development have succeed to promote normal development of recipient eggs. This difference in results between germ cell and somatic cell nuclear transfers could only be a reflection of intimate differences in their reprograming. These results suggest that PGC NT embryos are significantly higher for the in vitro development. Furthermore, These study may represent an approach towards achieving better production of transgenic animal.

The overexpression of Phosphoprotein Enriched in Astrocytes (PEA15) gene is commonly found in human diabetic patients. The overexpression of this gene in skeletal muscle and fat tissues have been reported to cause insulin resistance, thereby impairing insulin stimulated glucose uptake. We introduced a gene of mouse PEA15 (mPEA15) and enhanced green fluorescent protein (EGFP) into fertilized one cell pig zygotes using microinjection, and produced a piglet that showed overexpression of mPEA15 in the muscle tissues and expression of EGFP in the ear tissues and hooves. RT-PCR RFLP, southern blot and FISH analysis showed that the tissues carried the transgene. Real-time RT-PCR and western blots demonstrated that PEA15 gene was overexpressed in the various tissues and muscle tissues, respectively. These facts suggest that expression vector system is normally expressed in the trnasgenic (TG) pigs. To use as animal diseases model for type 2 diabetes, further study is necessary to confirm whether diabetes occur in these TG pigs, especially insulin resistance.

This research seeks to improve the understanding of corporate social responsibility (CSR) and its advantages in the shipping sector. Recently, an improved emphasis on CSR, which incorporates environmental and social concerns into economic considerations of firms, can be found in business management and marketing literature. This is mainly because of people’s increased awareness in regards to the negative consequences of corporate activities such as increased environmental pollution and gaps between the rich and the poor. According to the previous literature, it has been revealed that responsible actions by companies can generate positive outcomes in terms of financial and time aspects, but more importantly, intangible equity of the company, including improved corporate reputation, image as well as brand. As the regulation is intensifying in regards to environmental and social responsibility in the shipping sector, shipping companies are trying to engage in CSR to gain competitive advantages. While the reputation and image of shipping companies play essential roles for developing sustainable maritime transport, few studies have been conducted for how the CSR of shipping companies influence the shipping companies’ reputation and image relative to other industries. In this regard, this study aims to investigate the effect of the corporate social responsibility on corporate reputation and image of shipping companies on the basis of an exploratory study in the Republic of Korea. This research would be beneficial to both academics and practitioners for developing useful CSR strategies which could promote the public’s recognition of the shipping sector.

A simplified technique which cryoprotects zygotic embryos by encapsulation-dehydration was developed for the germplasm conservation of herbaceous peony (Paeonia lactiflora Pall.). The highest survival rate (85~%) was obtained from embryos treated by encapsulation-dehydration. The zygotic embryos were precultured on MS medium containing 0.3mg/L GA3 for 1 day. The precultured embryos were encapsulated in 3~% (w/v) alginate beads and immersed for 1 h in MS medium containing 2 M glycerol and 0.5 M sucrose. The encapsulated embryos were dehydrated for 5h by air drying prior to direct immersion in liquid nitrogen. This encapsulation-dehydration method appears to be a promising technique for germplasm cryopreservation of a herbaceous peony.