흰점박이꽃무지(Protaetia brevitarsis) 유충은 고단백·고지방·미네랄이 풍부한 식용곤충으로 기능성 식품 및 사료 소재로 주목받고 있다. 본 연구에서는 열풍건조, 동결건조, 마이크로파건조 세 가지 방법으로 건조한 흰점박이꽃무지 유충의 영양성분과 유해물질 함량을 비교하여, 건조 공 정에 따른 품질 및 안전성 차이를 평가하고자 하였다. 동일한 조건에서 사육한 유충을 각 건조방법으로 처리한 후 수분함량을 보정하여 일반성분, 지방산 조성, 아미노산 조성, 무기질 함량 및 중금속 함량을 분석하였다. 그 결과, 마이크로파건조 처리군은 조단백질(57.6 g/100 g), 조지방(17.7 g/100 g), 올레산(10.5 g/100 g) 함량이 열풍건조 및 동결건조 처리군보다 유의하게 높았고, 식이섬유와 칼슘은 동결건조 처리군에서 가장 높게 나타났다. 모든 처리군에서 중금속 함량은 국내 식용곤충 관리 기준을 충분히 하회하여 안전성이 확보되었다. 이러한 결과는 동결건조가 항상 영양 소 보존에 가장 유리하다는 통념을 보완하며, 건조 효율과 영양 농축 정도가 곤충 체조직 특성과 건조 조건에 따라 달라질 수 있음을 시사한다. 따라 서 흰점박이꽃무지 유충의 가공 과정에서 마이크로파건조는 영양 농축과 품질 확보를 동시에 고려할 수 있는 실용적인 대안 건조공정으로 활용될 수 있을 것으로 판단된다.

The lactic acid bacteria, Lactiplantibacillus plantarum KU15149 and Levilactobacillus brevis KU15176 were verified through phenotypic and genotypic analyses. Safety evaluation was conducted using multiple assays, including minimum inhibitory concentration assay for nine antibiotics, hemolytic activity, mucin degradation, gelatin liquefaction, urease activity, indole production, β-glucuronidase activity, bile salt deconjugation, cell cytotoxicity, D-/L-lactic acid production, and biogenic amine formation. Genotypically L. plantarum KU15149 and L. brevis KU15176 lacked all virulence and antibiotic resistance genes investigated. Consistent with these results, phenotypic assays showed that both strains were susceptible according to EFSA cut-off values and tested negative for hemolysis, mucin degradation, gelatin liquefaction, urease activity, indole production, β-glucuronidase activity, and bile salt deconjugation. Furthermore, neither strain showed cytotoxicity toward Caco-2 cells at a multiplicity of infection of 250. Production of D-lactic acid and biogenic amines was negligible in both bacteria. Overall, L. plantarum KU15149 and L. brevis KU15176 demonstrated safety and beneficial characteristics and therefore could serve as probiotic strains.

Lumpy Skin Disease (LSD) and Foot-and-Mouth Disease (FMD) cause substantial economic losses on the livestock industry. Therefore, vaccinations have been implemented as the control strategy in endemic countries. However, the potential adverse effects of administering vaccines for both diseases simultaneously have not been thoroughly evaluated. The aim of this study was to assess the impact of vaccinating dairy cows with either or both LSD and FMD vaccines on milk production and physiological parameters such as milk temperature, rumination time and body weight. The experimental groups were divided into four according to the injection materials: 1) saline, 2) LSD vaccine, 3) FMD vaccine, and 4) both vaccines. The impact of vaccination on milk yield and physiological parameters was evaluated daily until 12 days post-vaccination, and milk components were analyzed twice, once per week. Among the experimental groups as well as each vaccine group, no statistically significant differences (p < 0.05) were observed at milk yield, milk components, or milk temperature. This suggests that simultaneous vaccination of LSD and FMD can be administered without adverse effects.

발효 느타리버섯재배부산물을 급이한 흰점박이꽃무지 유충의 영양성과 안전성을 검증하고자 참나무 발효톱밥으로 사육한 유충의 영양성분 과 유해물질을 비교분석하였다. 조단백질 함량은 발효 느타리버섯재배부산물을 급이한 유충(OMCB)에서 54.0%로 참나무 발효톱밥을 급이한 유 충(FOS) 47.2%보다 1.1배 많았다. 필수아미노산 중 류신은 OMCB에서 2.8%로 가장 높았고, FOS에서는 2.7%로 비슷한 수치였다. 비필수아미 노산은 OMCB에서 프롤린의 함량이 7.2%로 가장 높았고 FOS (5.6%)보다 1.3배 더 높았다. 무기질 중 칼륨은 OMCB (2771.2 mg/100 g)와 FOS (2765.0 mg/100 g)에서 비슷한 수치였고, 불포화지방산 중 올레산은 OMCB (58.2%)와 FOS (59.6%)에서 가장 높은 함량을 나타냈다. 유 해물질 분석 결과, OMCB와 FOS에서 납, 카드뮴, 비소 모두 식용곤충 중금속 기준에 적합하였고, 식중독균에 속하는 대장균과 살모넬라균은 모두 불검출되었다. 위 연구 결과에 따르면, 발효 느타리버섯재배부산물 급이 흰점박이꽃무지 유충은 단백질과 불포화지방산뿐만 아니라 다양한 영양성 분을 포함하고 있으며, 안전성 또한 검증되었으므로 식용으로 활용하기에 적합할 것으로 판단된다.

The AlSi10Mg alloy has garnered significant attention for its application in laser powder bed fusion (L-PBF), due to its lightweight properties and good printability using L-PBF. However, the low production speed of the L-PBF process is the main bottleneck in the industrial commercialization of L-PBF AlSi10Mg alloy parts. Furthermore, while L-PBF AlSi10Mg alloy exhibits excellent mechanical properties, the properties are often over-specified compared to the target properties of parts traditionally fabricated by casting. To accelerate production speed in L-PBF, this study investigated the effects of process parameters on the build rate and mechanical properties of the AlSi10Mg alloy. Guidelines are proposed for high-speed additive manufacturing of the AlSi10Mg alloy for use in automotive parts. The results show a significant increase in the build rate, exceeding the conventional build rate by a factor of 3.6 times or more, while the L-PBF AlSi10Mg alloy met the specifications for automotive prototype parts. This strategy can be expected to offer significant cost advantages while maintaining acceptable mechanical properties of topology-optimized parts used in the automobile industry.

The emergence of ferrous-medium entropy alloys (FeMEAs) with excellent tensile properties represents a potential direction for designing alloys based on metastable engineering. In this study, an FeMEA is successfully fabricated using laser powder bed fusion (LPBF), a metal additive manufacturing technology. Tensile tests are conducted on the LPBF-processed FeMEA at room temperature and cryogenic temperatures (77 K). At 77 K, the LPBF-processed FeMEA exhibits high yield strength and excellent ultimate tensile strength through active deformation-induced martensitic transformation. Furthermore, due to the low stability of the face-centered cubic (FCC) phase of the LPBFprocessed FeMEA based on nano-scale solute heterogeneity, stress-induced martensitic transformation occurs, accompanied by the appearance of a yield point phenomenon during cryogenic tensile deformation. This study elucidates the origin of the yield point phenomenon and deformation behavior of the FeMEA at 77 K.

현대 사회에서 첨단 기술의 발전은 예술의 양상을 빠르게 변화시키고 있다. 생성형 인공지능 기술의 발전은 인류의 전유물이라 여겨왔던 창작 행위에 기존에는 보지 못했던 색다른 표현을 제공했다. 또한, 전통적 기법 을 고수하던 예술인들에게 새로운 예술 창작의 발현 방식을 제시하였다. 하지만 나날이 발전하는 인공지능 기술에 비해, 이를 활용한 구체적인 미디어아트 제작 과정 연구는 아직 국내에서는 미비하다. 본 논문은 인 공지능 기술을 활용한 미디어아트 해외 사례를 탐구한다. 그리고 Text-to-Image 인공지능 생성 모델과 게임 엔진 Unreal Engine 5를 이용하여, 국내에 자리 잡지 않은 생성형 인공지능을 활용한 작품 제작 방법론과 창 작자들에게 인공지능 이미지 생성 모델의 확장성을 제시한다.

Repetitive or excessive exposure to ultraviolet (UV) radiation causes oxidative stress-mediated skin photoaging through the overproduction of reactive oxygen species. Actinidia polygama is known as a medical plant used in oriental medicine for treating several diseases such as abdominal pain, stroke and rheumatoid arthritis. Recently, it was reported that A. polygama extract had anti-wrinkle and skin hydrating properties in ultraviolet B (UVB)-exposed hairless mice. However, the molecular biological mechanism of this extract on alleviating skin photoaging is still unknown. Therefore, we investigated the anti-photoaging effects of PB203, which is the powder of A. polygama extract, in the in vivo and in vitro photoaging models. First, PB203 showed 2,2’-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) and 2,2-diphenyl-1-picrylhydrazyl radical scavenging activities due to the presence of anti-oxidant components including flavonoids and polyphenols. In UVB-irradiated hairless mice, oral administration of PB203 (100 mg/ kg) significantly improved wrinkle formation, skin dehydration, elasticity and skin barrier function by decreasing the levels of matrix metalloproteinases (MMPs) and increasing those of collagen I, filaggrin, involucrin and loricrin. Especially, the reduced production of p-p38, p-c-Jun and p-c-Fos by PB203 reversed the elevated levels of MMPs mediated by UVB exposure, resulting in the upregulation of collagen I expression. Consistent with these animal data, PB203 remarkably enhanced the mRNA expression of collagen I, filaggrin, involucrin and loricrin, while suppressed that of MMPs in UVB-irradiated HaCaT cells. And PB203 increased the wound recovery rate of cells by promoting their proliferation and migration. Moreover, PB203 significantly recovered the activity of superoxide dismutase inhibited by UVB in both mice and cells. In conclusion, PB203, which protects skin from UVB-induced photodamage by exerting antioxidant properties, can be considered to have sufficient potential as a functional ingredient or therapeutic agent improving skin photoaging and related skin symptoms.

This study deals with replacement analysis of deteriorated equipment for improving productivity of production system. Frequent breakdown of the deteriorated equipment causes a situation that reduces productivity such as low product quality, process delay, and repair cost. However, the replacement of new equipment will be required a high initial investment cost, so it is important to analysis the economic feasibility. Therefore, we analyze the effect of the production system due to the aging effect of the equipment and the feasibility of equipment replacement based on the economic analysis. The process flow, working time, logistics movement, etc. are analyzed in order to build the simulation modeling for a ship and land switchboard production system. Using numerical examples, the economic feasibility analysis of equipment replacement through replacement of existing deteriorated equipment and additional arrangement of new facilities is performed.