Periodontitis is a chronic inflammatory disease characterized by the progressive destruction of periodontal tissue and alveolar bone loss. To develop effective treatment strategies, a model that mimics this disease must be implemented. From this perspective, animal models can be used to investigate its mechanisms by reproducing disease progression and providing insights into host-microbe interactions, immune responses, and bone remodeling. In addition, periodontitis-associated bone loss fundamentally differs from systemic bone loss. Targeted treatments require distinguishing periodontitis-induced and systemic bone loss mechanisms. This review examines the rationale for using animal models in periodontal research and evaluates various experimental approaches, such as bacterial inoculation, ligature-induced periodontitis, and chemically induced inflammation. These models have advanced our understanding of periodontal disease but have limitations in replicating the chronic nature of periodontitis and human immune responses. However, current models cannot fully replicate chronic disease progression and human immune responses. Recent developments have focused on improving animal models to more accurately simulate disease progression and host responses, which has led to the elucidation of the immunomodulatory mechanisms of periodontitis and their relevance to the human dental environment. Moreover, new approaches, such as developing age-related periodontitis models and improving ligature techniques, could enhance experimental reproducibility and translational potential. Future studies are needed to reflect these improvements and enhance the clinical relevance of periodontitis models.

X-ray diffraction is widely used as a non-destructive method for measuring residual stress in crystalline materials, and is particularly useful as a technique for controlling residual stress that has been introduced during the heat treatment or surface treatment of metallic materials. Neutron stress measurement is gaining attention as an internal material measurement method. It complements the demerits of the X-ray method in that it measures stress in a very thin surface layer. The neutron stress measurement method, like the X-ray method, is based on the principle of crystal diffraction, and its penetration depth is about 1,000 times greater than that of the X-ray method and is suitable for measuring the inside of a material. This study investigated the residual stress measurement method using the sin2ψ method using shot-peened mechanical structural carbon steel. The non-destructive measurement using high-energy X-rays was compared with the residual stress measured using conventional laboratory X-rays, and the following results were obtained. The high intensity diffraction angles using highenergy X-rays are low, but can be measured with sufficient precision. Interpreting the three diffractions 633, 552, and 721 as a single diffraction profile allowed stress measurements to be made, and the calculated value was close to the weighted average of the intensity ratios. The results of the high-energy X-ray residual stress measurements were in good agreement with the results from laboratory X-rays, confirming the usefulness of this method as a non-destructive method of assessing stress deep inside materials.

This study analyzes the discourse of Korean internet users regarding patient clothing and identifies the changes to structure and content of clothing resulting from infectious disease outbreaks. The analysis draws on texts from Korean blogs, internet cafes, and news articles from 2011 to 2021 related to patient clothing. Using Ucinet 5 and NodeXL 1.0.1 programs, network density, centrality, and cluster analyses were conducted using the Wakita–Tsurumi algorithm. Additionally, Latent Dirichlet Allocation (LDA) topic modeling was applied using Python 3.7 to further explore thematic patterns within the discourse. Throughout the period of study, it was found that users consistently discussed the specific purpose and functionality of patient clothing. Following the outbreak of COVID-19, the distribution and influence of keywords related to the functional aspects of patient clothing, such as “hygiene and safety,” significantly increased. An increased focus was placed on elements such as functionality, activity, autonomy, hygiene, and safety during the pandemic as public health concerns grew. It can be seen that patients increasingly share their experiences online and hospitalization rates surge during health crises; this study provides valuable insights into how the design of patient clothing can be improved through various informatics techniques. It underscores the evolving perception of patient clothing as essential medical equipment during health emergencies. In addition, it offers practical guidance for enhancing designs that better reflect shifting societal concerns, particularly regarding health, safety, and patient comfort.

This review examines the microstructural and mechanical properties of a Ti-6Al-4V alloy produced by wrought processing and powder metallurgy (PM), specifically laser powder bed fusion (LPBF) and hot isostatic pressing. Wrought methods, such as forging and rolling, create equiaxed alpha (α) and beta (β) grain structures with balanced properties, which are ideal for fatigue resistance. In contrast, PM methods, particularly LPBF, often yield a martensitic α′ structure with high microhardness, enabling complex geometries but requiring post-processing to improve its properties and reduce stress. The study evaluated the effects of processing parameters on grain size, phase distribution, and material characteristics, guiding the choice of fabrication techniques for optimizing Ti-6Al-4V performance in aerospace, biomedical, and automotive applications. The analysis emphasizes tailored processing to meet advanced engineering demands.

Visiting animal hospitals can induce significant stress in dogs, potentially adversely affecting their long-term health and behavior. This study systematically analyzed stress responses in dogs during veterinary visits and identified effective mitigation strategies through a comprehensive literature review. We selected using the keywords ‘animal hospital’, ‘veterinary examination’, ‘stress’, ‘handling’, ‘low stress’ and ‘dog’ from the PubMed database, during June 1 to July 31, 2024. A total of 19 studies were included and analyzed. An analysis of the literature showed that the presence of an owner played an important role in alleviating stress levels in dogs. Moreover, the owner's active participation in the inspection process was associated with a significant reduction in the stress response, especially during routine procedures that can cause anxiety. In addition, the implementation of low-stress processing techniques is recommended in order to minimize unnecessary stress, and these tools promote a more positive experience for the dog during the veterinary visit. Thus, the administration of pharmacological interventions such as trazodone and gabapentin prior to veterinary visits was shown to effectively reduce anxiety and stress, contributing to a more favorable overall experience for the animals. The results suggested that the importance of owner involvement, the systematic application of low-stress handling techniques, and careful use of pharmacological agents. Through this study, we believe that veterinary practices can develop a positive relationship with the clinical environment, which can ultimately improve health outcomes and increase well-being for canine patients.

The surface of titanium (Ti) dental implants was modified by applying a zinc (Zn)-doped titanium dioxide (TiO2) coating. Initially, the Ti surfaces were etched with NaOH, followed by a hydrolysis co-condensation using tetrabutyl titanate (TBT, Ti(OC4H9)4) and zinc nitrate hexahydrate (Zn(NO3)2 ‧ 6H2O), with ammonia water (NH3 ‧ H2O) acting as a hydroxide anion source. The morphology and chemical composition of the Zn-doped TiO2-coated Ti plates were characterized using X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), Raman spectroscopy, and scanning electron microscopy (SEM). Synthesis temperatures were carefully adjusted to produce anatase Zn-doped TiO2 nanoparticles with a bipyramidal structure and approximate sizes of 100 nm. Wettability tests and cell viability assays demonstrated the biomedical potential of these modified surfaces, which showed high biocompatibility with a survival rate of over 95 % (p < 0.05) and improved wettability. Corrosion resistance tests using potentiodynamic polarization reveal that Zn-TiO2-treated samples with an anatase crystal structure exhibited a lower corrosion current density and more noble corrosion potential compared to samples coated with a rutile structure. This method offers a scalable approach that could be adapted by the biomaterial industry to improve the functionality and longevity of various biomedical implants.

Fas-associated death domain protein (FADD) functions as an apoptotic adapter in mammals, recruiting caspases for death-inducing signaling complexes, while in lower animals, it interacts with IMD and DREDD to initiate antimicrobial responses. In this study, we examined the T. molitor FADD sequence (TmFADD) using molecular informatics methods to understand its involvement in the host's immune response against microorganisms. Knocking down TmFADD transcripts resulted in increased susceptibility of T. molitor larvae to E. coli, underscoring the significance of FADD in insect defense mechanisms and providing valuable insights into insect immunity.

Tenebrio molitor(T. molitor) is gaining attention as a sustainable food source with high nutrient content. Understanding their immune system, paricularly the role of Tak1 in the Imd pathway, is essential for mass breeding. This study investigates TmTak1 function in T. molitor. we investigated the immune function of TmTak1, followed by systemic infection using E. coli, S. aureus, and C. albicans. As a result, Silencing TmTak1 significantly affects expression levels of AMPs in the whole body, Fat bodies, and Integuments. These results showed lower expression levels of AMP compared to the control group during E.coli injection.

This study explores the profound impact of varying oxygen content on microstructural and mechanical properties in specimens HO and LO. The higher oxygen concentration in specimen HO is found to significantly influence alpha lath sizes, resulting in a size of 0.5-1 μm, contrasting with the 1-1.5 μm size observed in specimen LO. Pore fraction, governed by oxygen concentration, is high in specimen HO, registering a value of 0.11%, whereas specimen LO exhibits a lower pore fraction (0.02%). Varied pore types in each specimen further underscore the role of oxygen concentration in shaping microstructural morphology. Despite these microstructural variations, the average hardness remains consistent at ~370 HV. This study emphasizes the pivotal role of oxygen content in influencing microstructural features, contributing to a comprehensive understanding of the intricate interplay between elemental composition and material properties.

수국은 수국과(Hydrangeaceae) 수국속(Hydrangea)의 낙엽관목 식물로 크고 화려한 화형을 가져 절화, 분화 및 조 경수로 전세계적 인기가 있는 식물이다. 나무수국은 수국 (H. macrophylla)과 비교하여 삽목율이 낮은 것으로 알려져 있지만 나무수국의 묘목생산을 위한 삽목 연구 및 두 종간 삽목율 차이 원인 규명에 관한 연구는 미미하다. 본 연구는 IBA(Indol-3-butyric acid) 500mg·L-1 처리시 삽수의 침지 시간에 따른 삽목율 조사를 통해 적정 호르몬 처리 시간을 제 시하고 나무수국과 수국의 해부학적 구조 관찰을 통한 삽목율 차이 발생의 원인을 규명하고자 실시하였다. 나무수국의 적정 호르몬 처리 시간을 규명하기 위해 IBA 500mg·L-1을 무처 리, 30분, 2시간, 4시간 침지처리를 하였다. 종간 삽목율 차이 발생의 원인 규명을 위해 나무수국과 수국의 줄기 단면과 삽 목 후 시간 경과에 따른 발근을 해부학적으로 관찰하였다. 연 구의 결과 나무수국의 삽목시 IBA 500mg·L-1에 2시간 이상 침지처리가 다른 처리구와 비교하여 발근율이 높고 발생 뿌리 수가 가장 많았다. 또, 나무수국의 삽목율이 수국과 비교하여 낮은 것은 줄기의 세포 구조상 방사조직의 형태, 섬유세포의 밀도, 도관의 발달, 전분 함유 세포의 수 등에 차이가 관찰되 었고 이러한 세포 구조적 차이들의 영향으로 나무수국이 수국 보다 삽목 후 뿌리 조직 세포분열이 7일 늦게 시작되는 것이 확인되었다. 본 연구의 결과로 나무수국의 삽목 번식의 기초 자료로 활용되어 묘목 생산 효율 증대에 활용되길 바란다.

Emojis and avatars are widely used in online communications, but their emotional conveyance lacks research. This study aims to contribute to the field of emotional expression in computer-mediated communication (CMC) by exploring the effectiveness of emotion recognition, the intensity of perceived emotions, and the perceived preferences for emojis and avatars as emotional expression tools. The following were used as stimuli: 12 photographs from the Yonsei-Face database, 12 Memojis that reflected the photographs, and 6 iOS emojis. The results of this study indicate that emojis outperformed other forms of emotional expression in terms of conveying emotions, intensity, and preference. Indeed, the study findings confirm that emojis remain the dominant form of emotional signals in CMC. In contrast, the study revealed that Memojis were inadequate as an expressive emotional cue. Participants did not perceive Memojis to effectively convey emotions compared with other forms of expression, such as emojis or real human faces. This suggests room for improvement in the design and implementation of Memojis to enhance their effectiveness in accurately conveying intended emotions. Addressing the limitations of Memojis and exploring ways to optimize their emotional expressiveness necessitate further research and development in avatar design.

In the dismantling of nuclear power plants, various forms of radioactive gaseous waste are generated when cutting concrete and metal structures. Large amounts of radioactive dust and aerosols generated during the cutting process of each structure can cause radiation exposure to the environment around the workplace and to the radiation exposure in the body of workers. When cutting structures, water is sprayed to reduce the generation of aerosols, so early saturation of the filter is expected due to radioactive aerosols and fine particles containing a large amount of moisture. A mobile air purification device is being developed to a fast and efficient air purifier that can be used for a long time operation to protect workers from radiation exposure in high radiation areas and to minimize the amount of secondary waste generated. In this paper, the direction for a new concept of unit technology that can achieve the development purpose is described.

There is a large amount of radioactive waste in waste storage in the Korea Atomic Energy Research Institute. Some of the radioactive waste was generated during the dismantling process due to Korea Research Reactor 1&2 and it accounts for 20% of the total waste. Radioactive waste must be reduced by appropriate disposal methods to secure storage space and to reduce disposal costs. Research Reactor wastes include wastes that are below the acceptable criteria for selfdisposal and non-contaminated wastes, so they can be treated as wastes subject to self-disposal through contamination analysis and reclassification. In order to deregulation radioactive waste, it is necessary to meet the self-disposal standards stipulated in the Domestic Nuclear Act and the treatment standards of the Waste Management Act. The main factors of deregulation are surface contaminant, radionuclide activity and dose assessment. To confirm the contamination of waste, surface contaminant and gamma nuclide analysis were performed. After homogenizing the waste sample, it was placed in 1 L Mariinelli beaker. When collecting waste samples, 1 kg per 200 kg of waste was collected. The concentrations of the major radionuclides Co-60, Cs-134, Cs-137, Eu-152, and Eu-154 were analyzed using HPGe detector. To evaluate radiation dose, various computational programs were used. A dose assessment was performed with the analyzed nuclide concentration. The concentrations of representative nuclides satisfied the deregulation acceptance criteria and the results of the dose assessment corresponding to self-disposal method was also satisfied. Based on this results, KAERI submitted the report on waste self-disposal plan to obtain approval. After final approval, Research Reactor waste is to be incinerated and incineration ash is to be buried in the designated place. Some metallic waste has been recycled. In this study, the suitability of deregulation for self-disposal was confirmed through the evaluation of the surface contaminant analysis, radionuclide concentration analysis and dose assessment.