간행물
예방수의학회지 KCI 등재 Journal of Preventive Veterinary Medicine
- 발행기관 한국예방수의학회(구 한국수의공중보건학회)
- 자료유형 학술지
- 간기 계간
- ISSN 2287-7991 (Print)2287-8009 (Online)
- 수록기간 1978 ~ 2024
- 주제분류 의약학 > 수의학 의약학 분류의 다른 간행물
- 십진분류KDC 528DDC 636
권호리스트/논문검색
제48권 3호 (2024년 9월) 10건
1.
2024.09
구독 인증기관 무료, 개인회원 유료
Cerebral ischemia is a serious neurological disorder that can lead to high morbidity and mortality. Baicalin is a naturally bioactive flavonoid derived from Scutellaria baicalensis Georgi, which has neuroprotective activity. Baicalin exerts a neuroprotective effect against hypoxic ischemic injury. In this study, we investigated whether baicalin regulates specific proteins in the cerebral cortex of ischemic stroke animals. Middle cerebral artery occlusion (MCAO) surgery was performed to induce ischemic brain injury, and baicalin (30 mg/kg) or vehicle was injected into the abdominal cavity before MCAO surgery. Neurological behavior tests were performed 24 h after MCAO surgery and proteomics approach was performed using proteins extracted from cortical tissue. Two-dimensional electrophoresis analysis and MALDI-TOF were performed to identify the regulated protein by baicalin. MCAO damage caused severe behavioral disorders, but baicalin treatment improved these behavioral deficits. Baicalin also induced changes in the expression of various proteins in the cerebral cortex of MCAO animals. Proteins changed by baicalin administration are as follow: adenosylhomocysteinase, isocitrate dehydrogenase [NAD] subunit alpha, apolipoprotein A-I, Rab GDP dissociation inhibitor beta, eukaryotic initiation factor 4A, and mu-crystallin. These proteins were involved in metabolism and protein synthesis. The results of this study demonstrated the neuroprotective effects of baicalin by improving behavioral disorders caused by MCAO damage. The results also showed that baicalin regulates the expression of a variety of proteins involved in neuroprotective functions. Therefore, our findings provide evidence that baicalin plays a neuroprotective role in stroke animal models by regulating specific proteins.
4,000원
2.
2024.09
구독 인증기관 무료, 개인회원 유료
Escherichia coli is one of the major causative infectious agents of diarrhea in preweaning and postweaning pigs and leads to a large economic loss worldwide. However, there is limited information on the distribution and virulence genes in E. coli isolated from diarrheic piglets, which also applies to the current status of pig farms in Korea. To investigate the prevalence of virulence-associated genes in E. coli related to diarrhea in piglets, the rectal swab samples of diarrheic piglets were collected from Seoul National University’s veterinary pathological department between 2022 and 2023. E. coli strains were identified using the VITEK II system. Two sets of multiplex PCRs and one single PCRs used to detect 10 E. coli virulence genes. As a result, a total of 145 E. coli isolates were identified encoding one or more of the virulence genes. Among them, the prevalence of individual virulence gene was as follows, piglets virulence genes were STa 58.6%(85/145), STb 22.1%(32/145), LT 15.2%(22/145), EAST1 24.8%(36/145), Stx2e 6.9%(10/145), F4 31.7%(46/145), F5 1.4%(2/145), F6 11.7%(17/145), F18 4.1%(6/145), and F41 0.7%(1/145) respectively. These results suggest that E. coli disease in piglets may not be associated with a single toxin or a major gene combination, but with more varied and complex toxins and their combinations in Korea.
3,000원
3.
2024.09
구독 인증기관 무료, 개인회원 유료
This study investigates the effects of a sulfur spa product on the skin and hair health of dogs. With the rise in environmental pollution and health threats to pet dogs, interest in natural, non-irritating skin care products for dogs has grown. The study involved 15 Maltese dogs divided into three groups: a control group only shampooed, a water group soaked in tap water post-shampoo, and a sulfur group soaked in sulfur-infused tap water post-shampoo. Measurements of skin moisture, oil, skin barrier, and pH were taken from the dogs' back and abdomen after 60 minutes of treatment over six weeks. Additionally, skin condition and hair cuticles were analyzed using microscopes. Results showed that the sulfur group had significantly higher skin moisture levels in both the back and abdomen compared to the control and water groups. While there was no significant change in skin oil levels and skin barrier, the sulfur group had the lowest skin barrier, indicating a potential reduction in trans-epidermal water loss due to the detoxified sulfur. The pH levels were within the alkaline range typical for dog skin, averaging between 5.7 and 6.5. Visual observations revealed a reduction in dead skin cells and improvements in skin cleanliness. Analysis of hair cuticles showed that sulfur positively impacts hair smoothness and elasticity.
4,000원
4.
2024.09
구독 인증기관 무료, 개인회원 유료
Hanghee Cho, Taewon Kim, Cheol Ho Hyun, Kwang Yoon Shin, Yong Jik Song, Cheol-Ho Kim, Chung-Hui Kim, Hu-Jang Lee, Jae-Hyeon Cho
The present study, black soldier flies (Hermetia illucens) fermented using lactic acid bacteria were powdered without defatting and added to 3% or 5% to make pig feed. Weaning piglets were fed 3% (T3) or 5% (T5) feed powdered with Hermetia illucens for 5 months and the efficacy of the feed was investigated. The results of measuring body weight gain over 5 months after adding 3% (T3) or 5% (T5) of Hermetia illucens powder to the feed of weaned piglets showed significant weight gain in the T5 group compared to the control group. The added feed to Hermetia illucens powder did not show toxicity, and analysis of its effect on blood properties showed that white blood cell levels tended to increase in the T3 or T5 group compared to the control group.The only increase in white blood cell count was a change within the normal range. As a result of analyzing the effect of the level of addition of Hermetia illucens powder on feces, the effect of liquid reduction showed excellent results in the T3 treatment group and maintained the best form of feces. In this study, the thawing loss in the control group was 6.66%, and the T3 group with added powder to Hermetia illucens showed a significant decrease of 5.03%, and the T5 group also showed a decrease of 5.61%. Therefore, it was demonstrated that additive feed for Hermetia illucens reduced thawing loss, affected the water holding capacity of meat, and played an important role in maintaining the taste of meat. Moreover, the results of carcass grade showed a tendency for one grade to increase in the T3 and T5 groups fed additive feed to Hermetia illucens compared to the control group. In conclusion, the results of this study suggest that feed supplemented with Hermetia illucens is effective in influencing the weight gain of pigs, reducing the liquid content of feces, and increasing carcass grade.
4,000원
5.
2024.09
구독 인증기관 무료, 개인회원 유료
In-Ohk Ouh, Min Jung Kim, Kwang wook Kim, Hee ji Lim, Ye Jin Yang, Hu-Jang Lee, Woo H. Kim, Phil-Ok Koh, Seo Young Moon, Kyoung Hwa Choi, Yoo-Kyoung Lee, Kwang Il Park
This study evaluated the immunogenicity of the Bacillus Calmette-Guérin (BCG) vaccine in a guinea pig model to refine preclinical assessment methods. 24 guinea pigs were divided into four groups for immunohistochemical, histopathological, and molecular analyses, including qRT-PCR and ELISA. The ELISA results revealed significant elevations in interleukin 2 (IL-2), interferon-gamma (IFN- ), and tuberculosis-specific antibodies in vaccinated guinea pigs, particularly γ notable after 6 weeks. Although lung cytokine levels remained unchanged, spleen gene expression showed significant differences in interleukin-17, interleukin-12, interleukin-1β, and C-X-C motif chemokine ligand 10 after 6 weeks. Immunohistochemistry revealed peak IL-2 expression at 8 weeks and significant IFN-γ and TNF-α expression at 6 weeks. This study confirmed the effectiveness of BCG vaccine in guinea pigs, providing crucial insights for future tuberculosis vaccine development and standardizing immune response indicators.
4,000원
6.
2024.09
구독 인증기관 무료, 개인회원 유료
Visiting animal hospitals can induce significant stress in dogs, potentially adversely affecting their long-term health and behavior. This study systematically analyzed stress responses in dogs during veterinary visits and identified effective mitigation strategies through a comprehensive literature review. We selected using the keywords ‘animal hospital’, ‘veterinary examination’, ‘stress’, ‘handling’, ‘low stress’ and ‘dog’ from the PubMed database, during June 1 to July 31, 2024. A total of 19 studies were included and analyzed. An analysis of the literature showed that the presence of an owner played an important role in alleviating stress levels in dogs. Moreover, the owner's active participation in the inspection process was associated with a significant reduction in the stress response, especially during routine procedures that can cause anxiety. In addition, the implementation of low-stress processing techniques is recommended in order to minimize unnecessary stress, and these tools promote a more positive experience for the dog during the veterinary visit. Thus, the administration of pharmacological interventions such as trazodone and gabapentin prior to veterinary visits was shown to effectively reduce anxiety and stress, contributing to a more favorable overall experience for the animals. The results suggested that the importance of owner involvement, the systematic application of low-stress handling techniques, and careful use of pharmacological agents. Through this study, we believe that veterinary practices can develop a positive relationship with the clinical environment, which can ultimately improve health outcomes and increase well-being for canine patients.
4,000원
7.
2024.09
구독 인증기관 무료, 개인회원 유료
Eon-Bee Lee, Keon Kim, Cho-Yeon Lee, Ok-Mi Jeong, Chang-Min Lee, Se-A Lee, Hyun-Ok Ku, Moon Her, Sung-Won Park
Considering the various health problems associated with obesity in dogs, including renal diseases, joint disorders, and skin diseases, effective management strategies and guidelines are urgently needed. This situation has led to a growing demand for veterinary medications aimed at addressing obesity in dogs. However, the field faces a significant hurdle due to the absence of standardized guidelines for assessing the effectiveness of these anti-obesity medications in dogs. In response to this gap, the Animal and Plant Quarantine Agency (APQA) in Korea has made a crucial step by introducing clinical trial guidelines to evaluate the efficacy of treatments for canine obesity, specifically aimed at approving veterinary medicinal products. The guidelines outlined the selection criteria for target dogs, highlighting the importance of consistency within the control and treated groups. Treatment efficacy is subsequently evaluated by physical examination, body fat reduction, and biochemical indicators. In addition, the guidelines cover dosage and administration, monitoring after dosing, and statistical analysis. By doing so, this guideline not only highlights the significance of the APQA’s initiative in improving the care of obese dogs but also provides practical insights to enhance the standardization and effectiveness of clinical trials in veterinary medicine.
4,000원
8.
2024.09
구독 인증기관 무료, 개인회원 유료
Jiwon Yoon, Gunha Hwang, Yechan Moon, Youjin Na, NaYeong Oh, Jeongtae Kim, Sung-yong Kim, Hee Chun Lee, Tae Sung Hwang
A twelve-year-old, spayed female Siamese cat was presented for health screening. Abdominal radiography revealed a large amount of mineral opacity substances of various sizes and shapes, along with mild gaseous dilation proximal to the lesion. Ultrasonography showed hyperechoic surface with acoustic shadowing at the ileum and wall thickening of the ileum. Enterotomy was performed to remove the foreign bodies, which were numerous hairball- and stone-like objects. Analysis of the enteroliths revealed a composition of calcium phosphate. Although enterolithiasis is considered rare in cats, it should be included in the differential diagnosis when numerous pebble-like mineral opacity lesions are observed.
3,000원
9.
2024.09
구독 인증기관 무료, 개인회원 유료
This study evaluated the efficacy of a wild boar repellent (Repellent A) consisting of tannins and plant oils (castor oil, garlic oil, and cinnamon oil). Sixty farmed wild boars (4-8 months old) were divided into three groups: the normal control group (NC, n=20), the experimental group (EP, n=20), and the comparative experimental group (C-EP, n=20), which used Repellent B consisting of guaiacol, eugenol, menthol, thymol, and indole. EP and C-EP were equipped with four repellents per feeder, while no repellents were installed in the NC feeder. The feed intake and the number of feeding approaches were measured for one week in all groups. The number of approach of wild boars in feeders was monitored daily using a CCTV camera. The daily feed intake per farmed wild boar in EP and C-EP was significantly decreased compared to NC (p<0.05), and EP was significantly decreased compared to C-EP (p<0.05). In the average number of daily approaches, EP and C-EP were significantly decreased compared to NC (p<0.05), and EP was significantly decreased compared to C-EP (p<0.05). In conclusion, Product A has been confirmed to have excellent repellent effects on wild boars, and it could be used to prevent wild boars from approaching pig farms.
3,000원
10.
2024.09
구독 인증기관 무료, 개인회원 유료
Unlike companion cats raised at home, feral cats are more likely to be infected with parasites. Feral cats can transmit parasites not only to other cats but also to pets and people. This study was conducted to investigate prevalence intestinal parasites prevalence through the fecal examination of feral cats in Gunsan City. After making a suspension in Sheather's Sucrose solution, the feces were mixed and centrifuged, and then examined under a microscope. The results were revealed mostly unsporulated oocysts and sporulated oocysts of coccidia, followed by pinworm's eggs, which showed a relatively high infection rate. Scabies and mites were also found in the feces. Due to the behavioral characteristics of cats, they tend to remove the foreign objects from their fur through grooming, which is why a lot of hairs were observed in the feces, and it is thought that this is why scabies and mites were also found in the fecal examination results. The results of this study confirm that feral cats are exposed to those parasites. It is also thought that consideration should be given to expanding the TNVR (trap-neuter-vaccinate-release) program, which can reduce the number of feral cats.
4,000원
