This study was performed to investigate antioxidant and anti-inflammatory activities of perilla(Perilla frutescens L.) seed, flower and leaf according to extraction condition. Perilla seed extracts(PSE), perilla flower extracts(PFE), perilla leaf extracts(PLE) was extracted by stirring extraction (STE, 25°C), shaking extraction (SHE, 80°C), and sonication assisted extraction(SAE, , 25°C) with 94% ethanol, 60% ethanol and distilled water, followed by analysis of total polyphenol and flavonoid and testing radical scavenging activities. The highest total polyphenol content (5.47, 9.36, 38.58 mg gallic acid equivalent/g), total flavonoid content(5.77, 8.62, 46.44 mg catechin equivalent/g), ABTS(10.68, 19.46, 63.56 mg trolox equivalent/g) and DPPH(6.51, 7.69, 79.73 mg trolox equivalent/g) radical scavenging activity of PSE, PFE and PLE was observed in the HWE with 60% ethanol,. Among the three extraction method, SHE provided the best results for yield, polyphenol, flavonoid content of perilla seed, flower, leaf in comparison to STE or SAE. SHE with 60% ethanol of perilla seed, flower, leaf more effectively inhibited secretion of nitric oxide(NO) and pro-inflammatory cytokine in RAW 264.7 macrophage exposed to LPS compared to other extraction solvent and method. Therefore, these extracts obtained from perilla seed, flower, leaf could be used antioxidant and anti-inflammatory ingredients in the food industry.

Understanding the dispersion of xenon isotopes following a nuclear test is critical for global security and falls within the remit of both the Comprehensive Nuclear-Test-Ban Treaty (CTBT) and the International Noble Gas Experiment (INGE). This paper aims to show if it is possible to discriminate the source of xenon releases based on the atmospheric dispersion of xenon isotopes using HYSPLIT. Using ORIGEN and SERPENT simulations, four released scenarios are defined with four different fractionation times (i.e., 1 hour, 1 day, 10 days, and 30 days) after a 1kt TNT equivalent 235U explosion event. These time-delayed release scenarios were selected to certify the possibility of mis-determining xenon release source. We use the Lagrangian dispersion model for atmospheric dispersion to predict the concentration distribution of xenon isotopes under each scenario. The model allows us to better understand how these isotopes would distribute over time and space, offering valuable data for real-world detection efforts. To our knowledge, there have been no researches on the analysis of xenon isotopic ratios considering atmospheric dispersion. In this work, we focused on the atmospheric dispersion using HYSPLIT to characterize the xenon isotopic ratios from nuclear tests. In addition, we compared the xenon isotopic ratios obtained from the atmospheric dispersion with those from ORIGEN calculations, which would be helpful to discriminate the source of the xenon releases.

The objective of this study was to investigate the distribution of functional compounds in perilla leaves of various genetic resources and their antioxidant activities. A comprehensive analysis of functional compounds was conducted for 90 genetic resources, focusing on total polyphenol content (TPC), total flavonoid content (TFC), individual phenolic content (IPC), and lutein. Their antioxidant activities were then analyzed based on their radical scavenging capacity using ABTS (2,2’-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) and DPPH (2,2-diphenyl-1-picrylhydrazyl). The TPC content exhibited a range of 13.19 to 35.85 mg gallic acid equivalent/g, whereas the TFC content varied from 11.74 to 46.51 mg catechin equivalent/g. Total IPC was detected in a range of 6,310.98 to 40,491.82 μg/g. Lutein was detected at levels between 70.97 and 597.97 μg/g. ABTS and DPPH radical scavenging activities of perilla leaves ranged from 30.39 to 58.58 mg trolox equivalent (TE)/g and from 7.74 to 46.56 mg TE/g, respectively. Furthermore, correlation analysis demonstrated that rosmarinic acid, a phenolic acid, exhibited a significantly positive correlation with antioxidant activity. These findings suggest that various genetic resource of perilla leaves could effectively mediate antioxidant capacity. Results of this study provide valuable information for use of perilla leaves in Korea as functional food materials.

This study was conducted to investigate the effect of supplementary feeding levels on livestck and forage productivity and grazing intensity in Elk stags (Cervus canadensis). A fifteen 2-year-old Elk stags about 195 kg were randomly assigned to one of three dietary treatments (five animals per treatment). The dietary treatments consisted of a feeding concentrate of 1.0% of body weight (T1), 1.5% of body weight (T2) and 2.0% of body weight. Total dry matter intake (TDMI) was increased with increased with an increasing supplementary feeding levels. Average daily gain (ADG) were significantly increased with an increasing supplementary feeding levels (p<0.05) and reached a maximum on July and was lower in spring than autumn. The velvet antler production was no differences among treatment groups. Forage productivity of pasture and crude protein content were highest on May and decreased thereafter, however, crude fiber content was the reversed. The grazing intensity of Elk stags was increased in spring (38 to 59 head per ha) than summer and autumn (13 to 32 head per ha). The average grazing intensity of Elk stags ranged from 21 to 34 head per ha, which is affected by supplementary feeding levels. This result suggests that feeding supplementary diet at 1.5 % of body weight was needed to maintain the stable wight gain in antler growing periods and control the proper grazing intensity of Elk deer stags.

The first checklist of the Marsh Beetles (Coleoptera: Scirtidae) is presented based on literature records and specimens collected from Korean peninsula. The total of 19 species belonging to seven genera were catalogued. All recorded genus Cyphon species from Korean peninsula are transferred to genus Contacyphon by Zwick et al., 2013: Contacyphon coreanicus Klausnitzer, 1975, C. consobrinus Nyholm, 1949, C. laevipennis, C. padi (Linnaeus, 1758), C. palustris Thomson, 1855. Of these C. padi (Linnaeus), Hydrocyphon nakanei Yoshitomi, 2001, H. satoi Yoshitomi, 2001, Odeles inornata (Lewis, 1895), and Scirtes sobrinus Lewis, 1895 are recorded for the first time in South Korea. Photographs of dorsal adults and line drawings of diagnostic characters of new recorded Scirtids are provided. This work was supported by a grant from the National Institute of Biological Resources (NIBR), funded by the Ministry of Environment (MOE) of the Republic of Korea (NIBR201801201).

This study was conducted to investigate the effect of pasture grazing and barn feeding system on the growth performance, weight gain and velvet antler productivity in Elk. Twelve 5-year-old elk stags about 273 kg were stratified by weight and randomly assigned by feeding system (a pasture grazing and a barn feeding, n=6). The average feed intake were not signigicant difference between two groups. Average daily gain for grazing and barn feeding group was 0.25 g and 0.29 g respectively, showing no significant difference. Velvet antler yield for grazing and barn feeding group was 7,700 g and 6, 960 g respectively, with no significant difference. In conclusion grazing group was better than barn feeding group in feed intake, body weight gain and velvet antler productivity. However, there were no statistical significant difference between the two group. These results may serve as the basis for further study of deer feeding system in Korea and further study needed to examine the grazing intensity and economic efficiency.

이 연구의 목적은 지역 특화 주제형 과학동아리 활동이 학생들의 과학적 태도에 어떠한 영향을 미치는지 알아 보기 위한 것이다. 연구 대상은 우리나라 남부에 있는 소도시 소재 2개의 인문계 고등학교에 재학생 중인 92명이었다. 연구를 위해 지역 특화 주제를 정하여 운영하는 2개의 과학동아리 46명을 실험집단, 지역 특화 주제를 정하지 않고 일 반적인 수업을 운영하는 2개의 과학동아리 46명을 통제집단으로 선정하였다. 조사 내용은 과학에 대한 정의적 영역 중 과학적 태도와 관련된 검사지를 이용하여 대응표본 t-검증과 독립집단 t-검증을 실시하였다. 연구 결과, 첫째, 지역 특화 주제형 과학동아리 활동은 학생들의 과학적 태도에 긍정적인 효과를 나타냈다. 실험집단과 통제집단 모두 과학적 태도 의 평균점수가 동아리를 운영하기 전보다 향상되었지만 지역 특화 주제를 운영한 실험집단의 상승 폭이 통제집단의 상 승 폭보다 더 컸으며, 통계적으로도 유의미한 차이가 있었다. 둘째, 지역 특화 주제형 과학동아리 활동이 일상생활의 문제를 해결하는 학교, 가정, 사회 상황에서의 과학적 태도에 미치는 영향을 알아보기 위해 동아리 운영 전후에 실시한 검사 결과 통제집단에서는 유의한 차이가 없었지만, 지역 특화 주제를 운영한 실험집단에서는 가정과 학교 상황에서 통 계학적으로 유의한 차이가 있었다. 따라서 지역 특화 주제형 과학동아리 활동이 학생들의 과학적 태도에 많은 긍정적 영향을 끼치므로, 현장에서 과학동아리를 운영하는데 있어 하나의 프로그램으로 고려될 수 있다는 시사점을 도출할 수 있었다.

This study was conducted to determine grazing intensity of growing Korean native goats (Capra hircus coreanae) on mountainous pasture. It was carried out to obtain basic information for improvement of mountainous pasture management and establishing feeding system of Korean native goats. Castrated, male goats (n=10) with average initial body weight (BW) of 23.33±2.15kg and an average age of 4 months were used in this study. Grazing goats were supplemented by concentrates with 1.0% of BW. The crude protein content of forage was the highest in October (22.71±0.25%) and there were significantly differences (p<0.05) in monthly comparison. The forage productivity of pasture was the highest from May to June (1718.7±207.5~ 1672.0±422.8 kg/ha) but it was decreased in July (1356.0±103.8 kg/ha) because of drought and summer depression. Average daily gains (ADG) of goats were the highest in June (99.5±6.4 d/g). Grazing intensity was calculated by forage productivity and dry matter intake (DMI) and was the highest in May (65 head/ha). As shown in the results of this research, grazing intensity was suggested to average 39 head/ha from May to October. It is desirable that adequate grazing intensity was maintained by adjusting supplemental feed.

This research was conducted to evaluate the physicochemical properties of semi-dried jerky made from uncastrated (U) and castrated (C) deer meat. The jerky was manufactured by mixing the ground lean meat with spices followed by drying process, packed and stored aerobically at 25℃ for 20 days. The pH of uncastrated raw meat was significantly (p<0.05) higher than that of castrated meat as well as the pH of the jerky. No effects were found on color, hardness and sensory scores of jerky. Castrated jerky had higher fat content than uncastrated jerky (p<0.05), after 20 days of storage, its TBARS (thiobarbituric acid reactive substances) value was higher than uncastrated jerky (p<0.01). These results suggest that castration contributed to higher fat content and lipid oxidation of semi-dried venison jerky than the uncastrated, without any significant effects on texture and sensory attributes. However, proper packaging should be considered to inhibit lipid oxidation.

본 연구는 흑염소 사육을 활성화하고 경영의 효율성을 높일 수 있는 산지초지의 활용성 제고를 위한 기초자료를 제공하기 위하여 우리나라 흑염소 방목 이용 농가(20호)에 대한 실태조사를 실시하였다. 야초지로 이루어진 방목지의 경우 계절별 초지 생산성이 여름에 가장 높았으며(p<0.05), 봄철과 가을철에는 급격하게 저하되었다. 반면 목초지로 이루어진 방목지의 초지 생산성은 봄철에 가장 높은 생산성을 나타냈으며 가을철에 생산성이 다소 저하(p<0.05)되긴 하였지만, 대체적으로 계절별 생산성의 차이가 야초지 방목지에 비해 완만하여 비교적 안정적인 생산성을 나타내고 있었다. 계절별 방목지 초지의 사료가치 비교 결과 목초지의 경우 계절에 상관없이 안정적인 건물함량을 나타냈고, 야초지는 봄에서 가을로 갈수록 건물함량이 증가하는 경향을 보였다. 조단백질 함량은 목초지의 경우만 가을철에 증가하였고(p<0.05), 야초지의 경우에는 봄에 비해 여름과 가을에 감소하는 경향을 보였다(p<0.05). 목초지의 경우 야초지에 비해 상대적으로 조지방 함량은 높고 조섬유소 함량은 낮은 경향을 나타냈다. 계절에 따른 농장별 흑염소의 일당증체량은 농장별 초지 생산성 및 초지관리 기술에 따라 다양한 차이가 나타났다. 결과적으로 흑염소 사육의 활성화와 경영의 효율을 높이기 위하여 방목 야초지를 우수한 사료가치를 가지고 있을 뿐 아니라 계절별 생산성의 변화도 적은 방목 목초지로 갱신 및 조성을 해 나가야 할 필요성이 있으며, 산지초지의 효율적 이용을 위해서 초지관리 기술의 메뉴얼화와 보급으로 초지 생산성의 개선을 추구할 수 있는 방안이 필요할 것으로 사료된다.

Odontogenic cyst and odontogenic tumor shares developmental source. However, they have different histopathologic features, and they are classified respectively. Odontogenic cyst and tumor can share same physical region. It is called a hybrid lesion, a lesion showing the combined histopathological characteristics of two or more previously recognized odontogenic tumor and/or cysts of different categories. In this study, a hybrid lesion was researched. 61-year old man was referred to our department with a multilocular radiolucency in right mandibular angle. Incisional biopsy was carried out, and the patient was diagnosed with ameloblastoma. Odontogenic keratocyst was found with the tumor, and it was thought to be evolved via neoplastic transformation from lining epithelium of the keratocyst. After reviewing studies reporting hybrid lesions from odontogenic cyst and tumor, formation of a hybrid lesion was most frequent from a dentigerous cyst and an adenomatoid odontogenic tumor. A hybrid lesion commonly lead to misdiagnosis, and the prognosis is not always transparent. The close relationship between the odontogenic cyst and tumor has to be kept in mind in the diagnosis and treatment of the lesions in maxillofacial area.

We present a case of intraparotid plexiform neurofibroma in a 7-year-old man. The lesion was determined as plexiform neuroma in histopathological findings, but final diagnosis was plexiform neurofibroma considering his familiy history of neurofibromatosis and café au lait spots on his body. Currently we are executing follow-up after removing the tumor with surgery. Plexiform neurofibroma can develope at any point along a nerve and spread out either just under the skin or deeper in the body. According to the literature, the most common site of plexiform neurofibroma is mouth and face in the head and neck region. Also, plexiform neurofibroma occurs at 8.8-year-old in neurofibromatosis typeⅠ patient with familial history. Because of interlacing with adjacent normal tissue and the invasive nature we have difficult resecting the mass completely. So when the tumor turns symptomatic or disfiguring leading to an aesthetic problem, surgery had better be undertaken.

Proper oral hygiene is required to maintain oral health and prevent oral disease. Toothbrushing is central to proper oral hygiene. Mechanical tooth cleaning is the mainstay of plaque control. A variety of toothbrushing techniques have been developed and evaluated for their efficacy. However, these evaluations are subjective. To adequately evaluate toothbrushing objectively, a novel toothbrushing monitoring system was developed. The system involves user-monitored brushing patterns including toothbrush motions using a 3-axis gyroscope, 3-axis accelerometer, 3-axis magnetic sensor, one load-cell and Bluetooth devices. To confirm the efficacy of this toothbrushing monitoring system, eight periodontist performed tooth brushing in a dental model, and their brushing motion was monitored and recorded, and evaluated by statistical means. The proposed monitoring system can be used to aid dental care personnel in toothbrushing instruction.

We present a case of cellular angiofibroma arising from right neck in a 46-year-old woman. Surgical excision was performed and the patient was disease free till now. Cellular angiofibroma usually arised in the inguinoscrotal of vulvovaginal regions. Only 3 cases of cellular angiofibroma involving maxillofacial region have been reported in the english written literature. Cellular angiofibromas are rare benign tumor characterized by bland spindle shaped cells arranged in a stroma with wispy collagen and numerous vessels. Immunohistochemical stains of the tumor cells showed the positivity for CD34, PR, EMA, but negativity for neurofilament, desmin and actin. The tumor should be differentiated from aggressive angiomyxoma and angiomyofibroblastoma, angiofibroma because of its clinical and histological similarity. We report a rare case of benign cellular angiofibroma involving right neck and study other published articles.

The aim of this study was to carry out the comparative analysis of the brushing force following various brushing techniques bytoothbrush mounted pressure sensing unit. The study group consisted of 10 dental hygienist participants. The brushing forces (on buccal area of each first molar) were monitored on 8 different kinds of brushing techniques; Fones, Bass, Rolling, Scrub, Charters, stillman, Modified bass and Modified stillman. In Bass, Charters, Fones and Scrub method, force distributions showed a small gap of maximum and minimum value (Max/Min) while a big difference was noted in Modified bass, Modified stillman, Rolling and Stillman methods. Especially, the biggest difference of Max/Min value was observed in the area of lower left first molar. In conclusion, highly delicate manual skill is needed in showing big error range of force distribution. It means that careful force needs to be focused during toothbrushing instruction when a delicate manual skill was carried out.

The aim of this study was to perform a comparative analysis of tooth brushing patterns before and after education with a newly invented toothbrush. All participants performed toothbrushing on left lower first molar teeth for 10 seconds, using Modified bass method with the Newly invented toothbrush before education. After recording the brushing pattern, the participants were randomly classified into 1) Tell, 2) Tell-Show and 3) Tell-Show-Do group. After their education, toothbrushing patterns were recorded again. A comparative statistical analysis with a professional group was done by a one sample t-test. Each motion of toothbrushing was represented by Roll, Pitch and Yaw directions and pressure. After toothbrushing education, the Pitch, Roll direction and the value of pressure in all groups showed significantly similarity to the professional group. The Yaw direction appears to be improved after education, but the delineated motion was not considered to represent the Modified bass method. The patterns of each group were similar to the professional group as follows; Tell < Tell-Show < Tell-Show-Do. There was general evidence of higher educational effects by telling, monitoring and practical training. Finally, toothbrushing patterns were able to be analyzed by the Newly invented toothbrush correctly and quickly. This will contribute to the establishment of correct toothbrushing habits through public use.

Heavy metals such as cadmium and mercury are a highly toxic metal that affects a variety of cellular events, such as cell proliferation, differentiation and survival in animals as well as in human. The exposed heavy metals significantly affected the development and health in pubertal period. However, it is not clear how the toxicity of heavy metals in pubertal affects comparing in adults. To determine the effects of heavy metals on pubertal and adults, heavy metals such as cadmium and mercury were exposed to in pubertal and adults mice for 48 and 72h. Results showed that mice exposed to heavy metals for several hours induced overall tissue and organ damage. Especially, blood vessels of the most organ were more increased in adult mice compared to pubertal mice. And for morphologic alteration, secretary organs such as salivary gland and kidney were affected the most. Taken together, exposing to heavy metal in mice altered the blood vessels. In addition, the adverse effects of cadmium and mercury were more severe in adult mouse than puberty mouse. Further study is needed to focus on endothelial cells for more precise its mechanism

본 시험은 육성기 흑염소에 있어서 조사료원이 볏짚 위 주일 때, 농후사료 급여 수준이 발육, 사료이용성 및 경제 성에 미치는 영향을 구명하기 위해 실시하였다. 육성기 암 컷 흑염소 40두를 공시하여 농후사료 급여수준을 체중의 1.5% (T1), 1.8% (T2), 2.1% (T3) 및 자유채식구(T4)로 나누 어 급여 하였고 조사료원은 볏짚을 자유채식 하도록 하였 다. 그 결과, 일당 증체량은 T1 (1.5%), T2 (1.8%), T3 (2.1%) 및 T4(자유채식)구가 각각 50.23, 60.37, 71.46 및 98.90 g으로 농후사료의 급여 수준이 높아질수록 유의하게 높았으며(p<0.05), 조사료인 볏짚의 사료 섭취량은 농후사 료 급여수준이 증가 할수록 유의적으로 감소하는 결과를 보였다(p<0.05). 경제성 분석에 있어서 육성기 흑염소 경영 비는 농후사료를 1.5%, 1.8%, 2.1% 및 자유 채식하였을 때 각각 46,704원, 49,998원, 54,701원 및 74,613원으로 농후사 료의 급여수준이 증가할수록 경영비는 증가하였다. 이는 증체량에 있어서 T4(자유채식)구가 가장 많이 증가하였지 만 T3 (2.1%)구보다 사료비에 있어서 두당 19,912원 더 많 이 들었다. 이상의 시험 결과를 종합하여 고려할 때, 육성 기 흑염소에 있어서 조사료 원이 볏짚 단용일 경우에는 농 후사료를 2.1% 수준으로 급여하는 것이 가장 바람직할 것 으로 사료 된다.