본 논문에서는 다지지점 가진에 의한 구조물의 동적응답을 구하기 위하여 유한요소모형을 수정하고 등가하중을 도입하는 간단한 기법을 제안하였다. 제안방법은 다지지점 입력에 대한 해석기능이 있는 기존의 범용구조해석 S/W를 이용한 선형 및 비선형 해석결과와 비교하여 검증하였다. 이 기법은 다지지점 입력에 대한 해석기능이 없는 범용유한요소해석 S/W 및 비선형 구조해석을 위하여 특별히 개발되었던 전산프로그램을 이용하여 다지지점 입력에 대한 지진응답해석을 수행할 때 유용하게 활용될 수 있을 것으로 기대된다.

철골조 및 합성구조의 건축물이 강한 지진하에서 효율적으로 거동하도록 유도하는 연구중의 하나로서 개구부를 가진 합성보의 이력거동을 조사하고 있다 실험적 연구와 비선형 FEM 해석 연구 모두가 그러한 합성보의 연성도를 입증하엿다 합성보 단부 즉 기둥 면에서 발생할 수 있는 취성파괴 이전에 직사각형 개구부의 모서리 주변에 있는 4개의 T형 단면에서 소성힌지를 형성하며 합성보 전체의 연성도를 유지하고 있다. 본연구는 직사각형 웨브 개구부를 가진 합성보의 강도와 초기강성도를 산정하는 약산식을 제시하였고 그결과를 실험 및 비선형 FEM 해석의 결과와 비교 분석하였다.

This study investigates the stress distribution in a transversely isotropic medium containing a spheroidal cavity where the medium is under uniaxial tension in z;:iirection in one case and pure shear in the plane of isotropy in another case. The technical approach used in this study combines exact analytical and numerical methods. The exact analytical method is based upon three potential funct.ions taken in terms of the Legendre associated functions of the first and second kind. The numerical method is based upon the finite difference approach. Numerical results concerning the two loading conditions with fi ve anisotropic materials are presented.

들보나 아치, 판재 그리고 쉘과 같은 박판구조물의 경계부근의 매우 좁은 영역에는 경계층이 존재하는데, 이 영역에서 해는 급격하게 변화하는 특이 거동을 나타낸다. 유한요소법을 이용하여 이러한 물체의 거동을 해석하는 경우, 이런 특이성을 묘사하기 위해 유한요소 체눈패턴이 대단히 중요한 역할을 한다. 이 논문은 경계층에 대한 이론적 해석과 최적의 체눈패턴을 형성하기 위한 가이드를 제시한다. 또한 이론적인 결과를 입증하는 예제도 소개하고자 한다.

The purpose of the analysis is the numerical simulation of structures strained to the limit loads. The finite element calculations and experiments with cracked structures have been carried out yielding over limit strains between 10% and 15% by single peak load. Load versus displacement-diagrams and J-diagrams up to the limit load are calculated. By this way the influence of geometric parameters may be assessed in the post yield region. It is proposed to use such calculations to correlate experiments carried out with small specimens to experiments simulating the true dimensions of the design structure.

Four novel amphoteric surfactants of N-alkoxyethylcarboxybetaine series were synthesized via Schotten-Baurnman reaction between four alkyl chlorides contaning 10, 12, 14 and 16 carbon atoms in their N-alkyl group and dimethylaminoethanol to give the intermediate products, alkoxyethyldimethylamine, Quaternization of these intermediates was permitted to form 2-(alkoxyethyldimethylarnmonio) acetates, whose structures were identified by elemental analysis. IR spectrophotometry and 1Hnmr spectrometry. The yield of the final products was shown in the range of 74~77% based on the yield of the intermediate products, Surface tension of the aqueous solution of the final products was measured. and the critical micelle concentrations(cmc) were shown in the range of 2.82×10-3~2.67×10-6mol/l, and the surface thension at erne was 35~43dyne/cm. Cmc was lowered gradually by the increase of carbon numbers in N-alkyl ether containing group. The isoelectric point was shown in the range of 4.08~6.03. It showed a tendency to lean toward the acidic site and its range was broadened as increase of the hydrophobic group length. A linear relationship between log erne and the number of carbon atoms(N) in the hydrophobic alkyl chain was shown in the relative equation of log cmc=2.49-0.50N.

Four novel amphoteric surfactants of N-(2-alkylamidoethyl)-N, N-dimethyl ammonioacetates were synthesized. The each reaction between four saturated fatty acids containing 10, 12, 14 and 16 carbon atoms and N, N-dimethylethylene diamine permitted to give the intermediate products, N-(2-alkylamidoethyl)-N, N-dimethylamines. Quaterinzation of these intermediates was permitted to form N-(2-alkylamidoethyl)-N, N-dimethyl, ammonioacetates, whose sturctures were identified by CC, TLC, elemental analysis, IR pectrophotometry and 1HNMR spectrometry. The products yielded from 48% to 58%. The isoelectric points were shown in the range of 4.30~6.64. It showed a tendency to learn to the acidic site and its range was broadened as increase of the hydrophobic group length. Surface tensions of the aqueous solution in the 10-6~10-1mol/l of amidobetaines were measured. and the critical micell concentration(cmc) were shown in the range of 8.37×10-6~8.96×10-2mol/l, and γcmc were reduced to 32.3~38.2 dyne/cm. A linear relationship between log cmc and the number of carbon in the hydrophobic alkyl chain was presented by the formula of log cmc=2.38-0.5n, and the contribution-rate of n on the standard free energy change in micellization ɘ(δG0m)/ɘn, was calulated as -0.5RT.

Two perforated plates(a square plate and a rectangular plate having an as야ct ratlO 1.57(L,=11, L,= 7)) are taken as analysis examples. Each of these plates is given some changes in the boundary ∞nditions. The size of cutouts as well as their locations are also changed in order to examine the variation of two eigenvalues corresponding to the fundamental mode. The relationship between two eigenvalues is estab!ished by changing the magnitude of edge thrust

As a herbal supplement, Dioscorea batatas Decne (DBD) presents potent antioxidant activity and diverse health benefits. In the present study, functions of a 30 kDa glycoprotein isolated from DBD (hereafter, DBD glycoprotein) in the regulation of feed efficiency and fecal malodor in mice were explored. DBD glycoprotein produced protective effect against cytotoxicity induced by the ecotoxicological endocrine-disrupting substance bisphenol A in gastrointestinal epithelial HT-29 cells. To investigate its potential roles in the regulation of feed efficiency and fecal malodor, mice were administered an oral injection of DBD glycoprotein for 2 weeks. Compared with the control values, the weight of internal organs (liver, heart, kidney, and spleen) and levels of glutamate pyruvate transaminase, glutamate oxaloacetate transaminase, and lactic dehydrogenase were not significantly changed during DBD glycoprotein administration for 2 weeks. Interestingly, DBD glycoprotein improved feed efficiency and reduced hydrogen sulfide concentration without altering the ammonia level in mouse feces. Collectively, these results indicate that DBD glycoprotein is a functional agent that exerts gastrointestinal protective effects against ecotoxicological substances, improves feed efficiency, and reduces fecal malodor.

To develop eco-friendly microbial inoculants, siderophore-producing bacteria were isolated and identified, and their production characteristics and plant growth-promoting abilities were investigated. A strain S21 was isolated from rhizosphere of Korean perilla (Perilla frutescens) and identified as Enterobacter amnigenus by phenotypic properties and 16S rRNA gene sequencing. The highest siderophore production was obtained in a medium containing 0.5% fructose, 0.1% urea, 0.5% K2HPO4 and 0.1% succinic acid. By using this improved medium, siderophore production increased by 2.5 times compared to that of basal medium. The strain S21 showed insoluble phosphate solubilizing, ammonification and antifungal activities, and also produced hydrolytic enzymes (protease and lipase), indoleacetic acid and 1-aminocyclopropane-1-carboxylate deaminase. Our data suggest that E. amnigenus S21 is a potential candidate that can be used as eco-friendly biocontrol agent and biofertilizer.

Central precocious puberty (CPP) is less common in boys than girls; very little data is reported on effect of gonadotropin-releasing hormone analog (GnRHa) treatment in boys with CPP. The aim of the study was to evaluate growth changes in boys with CPP and early puberty (EP) treated with GnRHa therapy for 1 year. In 60 (39 CPP and 21 EP) boys with confirmed diagnosis of CPP and EP, auxological [height, height standard deviation score (Ht SDS), bone age (BA), Predicted adult height (PAH)] and endocrinological parameters were obtained at baseline, at 6 months, and at 1 year after GnRHa treatment in boys with CPP and EP. During the treatment a decline in Ht SDS and growth velocity, luteinizing hormone (LH), follicle stimulating hormone (FSH) and testosterone levels were observed (p＜0.01); and a deceleration in the maturation of bones after 1 year GnRHa treatment was observed (p＜0.01). PAH SDS was increased during treatment with GnRHa (p＜0.01). There was significant difference in PAH SDS between organic CPP and non-organic CPP (p＜0.05). The present data indicate that GnRHa therapy significantly improves growth prognosis in boys with CPP and EP.

교량의 정밀안전진단시 고유진동수의 추출은 반드시 필요하다. 교량의 고유진동수 추출을 위해서 일반 진단 실무에서는 동재하실험을 실시된다. 그러나 교량의 가진신호 계측이 어려워, 응답만으로 고유진동수를 추출하여야 한다. 차량의 중량이 교량의 중량 대비 매우 작은 경우에 문제가 없으나, 차량의 중량이 무시 못할 정도로 큰 경우에는 차량 주행에 따른 가진 주파수가 응답스펙트럼에 나타나고, 진단 실무자는 종종 가진 모드를 교량의 1차 모드로 오인하는 경우가 적지 않다. 본 연 구는 교량의 고유진동수와 차량의 가진모드를 쉽게 구별할 수 있는 실무적인 방법을 제안한다.

Curcumin (C21H20O6) is a hydrophobic polyphenol found in turmeric. Although curcumin has been used as a natural medicine, its major limitation is related to poor absorption from the gut. Therefore, we developed a method for preparation of Curcumin Nanospheres (CN) to improve the aqueous-phase solubility of curcumin and investigate the functional role of CN in promoting feed efficiency and odor reduction in mice. CN showed inhibitory effects on actate dehydrogenase (LDH) cytotoxicity induced by ecotoxic substance toluene in gut epithelial HCT116 cells. In addition, the weights of internal organs (liver, heart, kidneys, and spleen) and the levels of serum Glutamate Oxaloacetate Transaminase (GOT), Glutamate Pyruvate Transaminase (GPT), and LDH did not show significant differences between mice administered oral CN for two weeks and compared to the control group. Interestingly, CN not only reduced hydrogen sulfide (H2S) and ammonia (NH3) levels and fecal odor, but also improved feed efficiency in mice. These results demonstrate that oral nano-delivery of anti-ecotoxicological CN is a functional system to deliver curcumin to the gut to improve feed efficiency and reduce fecal odor in mice.