Purpose: This study attempted to enhance the nurses’ safety competence in administering medications by using simulation training focused on high-alert medication. Method: A total of 30 nurses from 14 teams participated in the simulation training using a high-fidelity patient simulator. Medication administration performance and built-in error recovery was observed using a medication administration safety assessment checklist. Medication safety knowledge and confidence were measured before and after simulation training. Data were analyzed using descriptive statistics and a paired t-test. Results: There were numerous variations in safe medication administration. The safety behavior by oral prescription was insufficient compared to that by routine medication prescription. Following simulation training, knowledge of medication safety increased significantly, but confidence did not. Conclusion: Nurse educators may consider simulation to be an effective strategy for enhancing nurses’ medication safety competence.

Recidivism Risk (RR) has been the most interesing area in criminals, hence many 'life-saving programs' have been implemented, including life support, employment support, family support, and counseling support projects. Yet, there has been little empirical research on the effects of anxiety and the perceived social supports in prison on RR. The goal of this study was to investigate the relationship among state and trait Anxiety, social support resources, and risk of recidivism among prisoners. Furthermore, the mediating effect of social support resources was analyzed for exlaining the association between state and trait anxiety and RR. 500 male prisoners at the 'P' correctional institution (A heavy security facility (S4 level) located in B Metropolitan City among correctional institutions under the Ministry of Justice) was collected. Structural equation modeling using the survey responses of STAI, social support scale, and recidivism risk scale was conducted. We measure two parts of anxiety (state and trait)and four sub-factors in social support resources (emotional, evaluatative, informational, and financial support). In addition, twenty-three sub areas of RR were measured including individual background information and psychological factors. The results found that (1) anxiety had a significant effect on RR. In more detail, the trait anxiety is higher effect on RR than the state anxiety. The social support also had a significant positive effect on RR in order of evaluative, emotional, informative, and finacial support resource. Lastely, the social support played a significant partial mediating role in the relationship between anxiety and RR. These foundings confirmed that the prisoners’anxiety could increase the RR and the RRcan be decreased if the prisoners are perceived that they had social support resources. Therefore, this study implies that the perceived social support among prisoners can play a protective factor in decresing RR among prisoners with anxeity.

This study derived elements from the Technology Acceptance Model (TAM) and the Theory of Planned Behaviour (TPB) to assess factors influencing attitude and intention to use drones for medications delivery among Generation Y consumers. Data was collected from 300 respondents. The results revealed that attitudes towards the use of drones for medicine delivery were influenced by perceived service quality, usefulness, and service value. Subjective norms, usefulness, service value and attitudes impacted behavioural intention. This study contributes in distribution strategy literature. It also enriches information on the drone delivery capabilities as well as the accessibility of medications through drones.

This study was planned to evaluate the efficacy of surgical treatment in stage 2 medication related osteonecrosis of jaw(MRONJ) patients. Retrospective analysis was performed about patients who were treated with medication related osteonecrosis of jaw from 2015 to 2017. 25 Patients were treated by a single surgeon at the Department of Oral Surgery, Dental Hospital, Pusan National University. The treatment methods they received were conservative or surgical. The results of treatment were classified as "fail" and "success" and the prognosis according to the treatment method was compared. Conservative treatment 14.29% (2 cases), sequestrectomy 64.29% (9 cases) and saucerization 21.43% (3 cases) were performed in the MRONJ group, and 2 treatment failures were encountered after conservative treatment and 1 after saucerization. Surgical treatment resulted in better outcomes in stage 2 MRONJ patients. Furthermore, treatments were deemed successful when surrounding necrotic bone containing sequestrum was reliably removed. Therefore, this study suggests that the treatment of "stage 2" MRONJ should actively consider surgical treatment.

Osteonecrosis is defined as non-vital bone tissue as a result of abnormal process of osseous healing, and is caused by several reasons such as infection, radiation, and medication. Osteomyelitis, osteoradionecrosis, and medication related osteonecrosis of the jaws (MRONJ) which have necrotic bone in common are confused clinically due to similar symptoms and radiographic findings, and are difficult to diagnose definitively. Because each disease represents a separate clinical progress and requires a different treatment approach, it is very important to distinguish each disease. The aim of this study was to analyze the histopathologic features of osteomyelitis, osteoradionecrosis, MRONJ and to understand their different pathogenesis.

만성 췌장염은 심한 췌장 실질의 파괴로 인하여 통증, 외분비 및 내분비 기능 장애가 발생하는 질환이다. 만성 췌장염의 임상 양상은 심하고 지속적이며 잘 조절되지 않는 복통과 흡수장애, 당뇨병을 특징으로 한다. 만성 췌장염은 난치성 복통 외에도 원인, 외분비기능, 내분비기능 모두가 일련의 톱니바퀴처럼 맞물려 있다고 생각해야 한다. 단순하게 복통 만을 조절하려고 하거나 흡수장애 만을 고려한 치료는 또 다른 합병증을 유발 할 수 있다. 반면, 원인, 통증, 외분비기능, 내분비 기능을 모두 고려한 다중 접근은 환자의 증상만이 아 니라 삶의 질을 회복시켜 주고 새로운 삶의 원동력을 제공할 수 있다.

Acute pancreatitis is an inflammatory disease of the pancreas. Acute abdominal pain is the most common symptom, and increased concentrations of serum amylase and lipase confirm the diagnosis. Pancreatic injury is mild in 80% of patients, who recover without complications. The remaining patients have a severe disease with local and systemic complications. Acute pancreatitis is a hypercatabolic state resulting in rapid loss of body weight, fat and protein. Nutritional support is an integral part of patient care and is started early in the course of disease. Patients with mild to moderate disease (80% of patients) do not require enteral nutrition (EN) or parenteral nutrition(PN), as they will begin oral feeding within 4 days of presentation. Nutritional support is needed for severe disease, EN is preferred over PN, and use PN when EN is contraindicated or not feasible. Most groups have used nasojejunal feeding, which has difficulties in maintenance of the tube position and patency. Nasogastric feeding in severe AP has shown little difference in terms of clinical outcome from nasojejunal feeding. In this review, we review the role, methods, and clinical implications of nutritional supports in acute pancreatitis and also present recently recommended standard guidelines.

담석증은 흔한 소화기질환 중 하나이며, 비만, 여성, 장기 간의 금식, 빠른 체중감량, 총 경정맥영양 등 담석발생의 다양한 위험인자가 알려져 있다. 증상이 있는 담석의 치료는 담낭절제술이 일반적인 치료이다. 무증상 혹은 경한 증상을 보이는 담석증에서 담즙산제제인 UDCA가 담도산통의 유발이나 급성 담낭염, 급성 췌장염과 같은 합병증 발생을 낮춘다고 알려져 있으나, 대규모 전향적 연구가 필요한 실정이 다. 담석, 특히 콜레스테롤 담석의 발생에 영향을 미치는 식이요소들로는 고콜레스테롤, 포화지방산, 정제된 탄수화물, 설탕 들이 있다. 예방적 효과를 보이는 식이는 불포화지방산, 섬유질, 커피, 적당양의 알콜 등이 있다. 또한 특정 음식 에 대한 과민반응으로 담석 증상이 발혈 될 수 있으며, 그 외 영양 첨가물로 비타민 C, 레시틴, 철분 등이 영향을 미칠 수 있고, 식물 terpenes 복합물도 도움이 될 수 있다.

Halitosis is a major problem on social interactions in many people, and oral hygiene control is a major treatment for halitosis. However, medication may be the choice of method for non-oral origin halitosis. The present study evaluated the efficacy of chlorophyllin medication for oral malodor patients with GERD (gastroesophageal reflux disease). 26 patients with halitosis visited Department of Periodontology of Seoul National University Bundang Hospital. VSCs (Volatile Sulfur compounds) level was evaluated according to Chlorophyllin medication after 20 days’ medication. Scaling was conducted after medication, and VSCs level was measured 28 days after scaling. Chlorophyllin medication on the halitosis patients with GERD showed a statistically significant efficacy (P > 0.05). There was no significant effect on the patients without GERD (P>0.05). There was no significant effect s caling before o ne month ( P>0.05). Chlorophyllin was e ffective in t he halitosis patients with GERD. There was no significant difference one month after scaling.

방사선과 paraquat에 의해서 유도된 간 손상에 대한 홍삼추출물의 보호효과를 비교 연구하였다. ICR계 생쥐에게 X선의 5Gy조사와 paraquat투여 7일 전부터 홍삼추출물(200mg/kg/day)을 투여하였다. 대조군은 생리적 식염수를 투여하고 방사선조사군은 생리적 식염수를 투여하면서 5Gy를 조사하였다. 홍삼추출물 투여군은 7일 전부터 홍삼추출물(200mg/kg/day)을 투여하면서 5Gy를 조사하였다. Paraquat투여군은 7일 전부터 홍삼추출물(200mg/kg/day)을 투여하면서 paraquat(30mg/kg/day)를 투여하였다. 그리고 각각의 실험군에서 간조직의 H2O2, catalase, MDA를 측정하였다. 그 결과 방사선조사군과 paraquat투여군보다 홍삼추출물 투여군에서 catalase함량이 유의성 있게 증가하여 간의 보호효과가 있었으며 H2O2와 MDA함량도 유의성 있게 감소하였다. 홍삼추출물은 간 조직에 대한 방사선조사 및 paraquat투여로부터 매우 우수한 방호제라고 할 수가 있다.

본 논문에서는 선박에서 장부상의 수기기록으로 보관되는 의약품에 대한 관리를 데이터베이스화하여 효율적으로 관리하고 환자에 대한 약품투여내역을 전산화함으로써 선원 개개인에 대한 건강상태와 약품 오남용을 파악할 수 있게 하였다. 노한 선박에서 의약품 재고에 대 한 세부내역을 무선 통신망을 통하여 원격 전송함으로써 선박 의약품 비치기준량을 파악하는데 필요한 시간과 업무량을 감소시켰다. 협소한 통신대역폭을 감안하여 서버모듈과 클라이언트모듈을 개발하되, 이에 따른 의약품 코드체계와 프로토콜을 설정하였으며, 선박에서 원격 데이터베이스의 약품정보를 전송할 수 있게 하였다.