국산 안개초 ‘Dream Song’ 가을~초겨울 절화 재배시 개화 촉진 및 절화 생산성 향상에 적절한 광원 선발을 위해 전조 광원별 생육 및 개화특성을 조사하였다. 백열등의 광질은 청색, 적색 및 원적외선 파장 모두 높고 고압나트륨등(HPS)은 적색 파장이 약간 높았으며, LED는 청색이 적색 파장보다 높았고 삼파장등은 청색과 적색 파장이 낮게 조사되었다. 주간(13:00)과 야간(전조 1시간 후, 23시)에 측정한 엽록소 형광 반응은 광원별로 차이가 없었다. 백열등과 고압나트륨등이 생육 진전이 빨라 출뢰 및 개화가 촉진되었으며, 화경장과 절화장이 길고 분지수와 개화율이 높아 절화량도 많았다. LED 전조는 개화 촉진 효과는 적었으나 분지수가 향상되었다. 따라서 경영비를 고려한 국산 안개초 ‘Dream Song’ 전조 재배 시 광원은 백열등이 적정하다고 생각된다.

본 연구는 경기도 31개 시군의 과학기술역량을 정확하게 파악하기 위하여 실증분석을 실시하고 그 결과를 지도화하여 시사점을 도출한 뒤 지역별로 역량에 맞는 정책방안을 제시하는 것이 목적이다. 비교적 객관적인 분석의 결과를 얻기 위하여 COSTII, R-COSTII와 그 논리적 맥락을 같이하여 혁신자원의 투입에서 성과에 이르는 전 과정을 혁신자원, 혁신활동, 혁신과정, 혁신환경, 혁신성과 등의 5개 부문으로 구조화한 G-COSTII 지표를 개발하여 이용하였다. 경기도 내 31개 시군에 대한 기초지자체 과학기술혁신역량분석의 종합결과를 지도화하면 지역별 또는 권역별로 과학기술역량의 차이가 상이한 것으로 나타나고 있다. 경기 남·북부 간에 과학기술역량의 차이를 보이는데 구체적으로 역량이 높은 기초지차체는 주로 경기도 남부, 경부권과 서해안권에 자리하고 있음을 알 수 있었다. 경부권은 혁신자원 및 혁신환경이 우수하며 서해안권이 활발한 혁신활동과 혁신과정을 하고 있음을 알 수 있었다. 본 연구에서는 이러한 차이를 바탕으로 세부지역별 혹은 권역별 맞춤정책의 필요성을 확인할 수 있었다.

본 연구는 산업집적의 공간적 패턴과 구조를 분석하여 고집적지(핫스팟)를 찾는 데 있다. 이를 위해 본 연구는 경기도 지식기반산업을 대상으로 경기도 31개 시·군 및 538개 읍면동 단위를 분석하였다. 분석을 위해 이용된 방법은 대표적인 공간통계기법 중 고집적지를 찾는데 탁월하다고 알려진 Getis-Ord’s Gi *와 입지계수(LQ: Location Quotients)의 약점을 보완하고자 제시된 Flegg’s Location Quotients (FLQ)이다. 이 방법들로 찾은 고집적지는 공통적으로 비슷한 지역을 찾아내고 있는 것으로 분석되어 집적분석을 통해 산업을 분석하기 위한 기초자료로 활용될 수 있을 것으로 보인다. 본 연구는 산업의 공간적 분포패턴을 종합적으로 분석하는 방법론을 제시하였다는 데 의의가 있으며 이를 통해 경기도가 추구하는 지역혁신체계를 추구하기 위한 클러스터 정책을 펼치는데 유용한 정보를 제공해 줄 수 있을 것으로 보인다.

Poor oral hygiene can cause severe periodontal disease. Therefore, it is necessary to educate individuals regarding the importance of maintaining good oral hygiene. To this end, in this study, we evaluated the efficacy of using a phase contrast microscope as an instructional tool for oral hygiene. Forty patients, randomly divided into test and control groups, were recruited 6 months after receiving oral prophylaxis. A phase control microscope was used as a demonstration tool for the test group, and a dentiform model was used to demonstrate the ideal tooth-brushing method for the control group. In the test group, awareness regarding the importance of proper oral hygiene was found to increase by 30%, and in the control group, awareness was increased by 20%. The overall satisfaction with the instructional program was 80% in the test and 70% in the control group. The level of understanding was 99% in the test and 80% in the control group. Instructions were easily followed by 80% of the test and 60% of the control group. Understanding of the program was significantly higher in the test group than in the control group (p < 0.05). The overall satisfaction and understanding of proper oral hygiene was over 70% for both the groups. The phase contrast microscope-based instructional program yielded higher actual practice rates. The phase contrast microscope is desirable tool for motivating patients and spreading awareness regarding the importance of maintaining good oral hygiene.

선거구 구획문제는 선거구를 인구등분, 인접성, 공간적 조밀도 등의 일정한 기준에 따라서 나누는 작업을 말한다. 미국의 경우 의회 선거구는 필수불가결한 요소로 완벽한 인구 등분과 인접성을 헌법으로 요구하고 있다. 그러나 기존의 휴리스틱은 여러 가지 선거구 선정요인들을 동시에 만족시키는데 주력하고 있어 의회선거구에 맞는 완벽한 인구등분을 가진 선거구 플랜을 찾는데 한계를 보이고 있다. 그리하여, 이 논문에서는 의회선거구 구성 요건에 맞는 선거구 구획 연구를 하고자 최적화 연구방법 중 시뮬레이티드 어닐링(모의 담금질 기법) 휴리스틱 기법을 기본 바탕으로 선거구를 구획하였다. 또한 새로운 인접성 방법을 제시하여, 구획연구를 하는데 있어 하나의 접근법으로 제시하고자 한다. 연구 결과 이 논문에서 이용된 기법은 실제 이용 중인 선거구 플랜보다 훨씬 더 인구등분에 가까운 선거구 플랜을 찾아내며, 효과적으로 인접성 문제를 해결하고 있음을 알 수 있었다. 또한, 새로 개발한 휴리스틱은 다양한 선거구 플랜을 제시하고 있어, 의사결정자들로 하여금 선택의 용이성을 제공하고 있음을 알 수 있었다. 이러한 시도는 의회 선거구를 구성하는데 있어서 새로운 대안으로 제시될 수 있을 것이다. 또한, 이러한 선거구 선정 연구는 한국의 국회의원 선거구 선정문제에서 인접성과 인구등분의 선정기준을 이용할 시 적용 할 수 있다는데 그 의의가 있다.

Halitosis is a major problem on social interactions in many people, and oral hygiene control is a major treatment for halitosis. However, medication may be the choice of method for non-oral origin halitosis. The present study evaluated the efficacy of chlorophyllin medication for oral malodor patients with GERD (gastroesophageal reflux disease). 26 patients with halitosis visited Department of Periodontology of Seoul National University Bundang Hospital. VSCs (Volatile Sulfur compounds) level was evaluated according to Chlorophyllin medication after 20 days’ medication. Scaling was conducted after medication, and VSCs level was measured 28 days after scaling. Chlorophyllin medication on the halitosis patients with GERD showed a statistically significant efficacy (P > 0.05). There was no significant effect on the patients without GERD (P>0.05). There was no significant effect s caling before o ne month ( P>0.05). Chlorophyllin was e ffective in t he halitosis patients with GERD. There was no significant difference one month after scaling.

The purpose of this study was to assess the effect of bridging stabilization exercises on trunk muscles activity on and off a Swiss ball. 20 healthy university students volunteered to participate in this study. Subjects were required to complete following four exercises: exercise 1, single bridging exercise; exercise 2, feet on ball bridging exercise; exercise 3, calf on ball bridging exercise; exercise 4, back on ball bridging exercise. Surface electromyography from selected trunk muscles was normalized to maximum voluntary isometric contraction. A repeated measures of ANOVA with post-hoc Bonferroni's correction was used to determine the influence of exercise type on muscle activity for each muscle and descriptive statistics was used to determine local/global muscle ratios. The rectus abdominis of exercise 4 showed significantly higher muscle activity than rectus abdominis of exercise 1, 2, 3 (p<.05). The external oblique of exercise 2, 4 showed significantly higher muscle activity than external oblique of exercise 1 (p<.05). The internal oblique of exercise 2, 4 showed significantly higher muscle activity than internal oblique of exercise 1 (p<.05). The erector spinae of exercise 2, 3, 4 showed significantly higher muscle activity than erector spinae of exercise 1 (p<.05). Median of internal oblique/rectus abdominis ratio of exercise 1 was 1.16, exercise 2 was 2.43, exercise 3 was 2.45, exercise and 4 was 1.27. Median of internal oblique/external oblique ratio of exercise 1 was 1.01, exercise 2 was .91, exercise 3 was .99, and exercise 4 was .93. Muscle activity can be influenced by addition of a Swiss ball in bridging exercises. It is recommend to use a Swiss ball for trunk stabilization exercise.

The major component of green tea is (-)-epigallocatechin-3-gallate(EGCG) which accounts for 5080% of catechin, representing 200300 mg in a brewed cup of green tea. EGCG has been known to possess growth inhibitory and pro-apoptotic effect on human cancer cell lines such as prostate, bladder and breast cancers. In contrast, several studies have suggested that EGCG could promote cell proliferation and/or survival instead of pro-apoptotic effect. Understanding how intracellular signaling pathways respond to EGCG may provide a clue to the difference of cell responses and basis for usefulness of EGCG as a chemopreventive and/or chemotherapeutic agent. To better understand the mechanisms responsible for the chemopreventive efficacy of EGCG, the authors tried to identify the key molecules that contributes to Akt activation and can inhibit this activation. In the present study, EGCG increased Akt phosphorylation, an activeform of Akt and negatively affect on direct upstream molecules of Akt including PTEN and EGFR, though Akt phosphorylation was increased.

( - ) -epigall ocatechin - 3 -ga ll ate(EGCG) 는 녹차에서 추출되는 주된 성분으로 항산화. 세포 증식 억제 및 세 포 자멸사를 유도힌다 고 알려져 있다‘ 현 재 끼지의 여러 연구에 의하띤 EGCG는 세 포 성장을 억제하고 나아가서는 apoptoS1S까지도 유발한다. 한편 일부 연구는 EGCG가 오히려 apo ptosi s를 억 제 하고， 세 포 증식을 촉진한다고 보고하고 있다. 저자들은 EGCG가 이러한 상반된 효과틀을 보이게 되 는 기전과 그에 관련된 물질들을 파악하고지 하였다， EGCG를 세포에 처리시 초기에는 세포 생존에 관여힌다고 알려진 인 산화된 Akt 단백이 증가함이 관찰되었다 그 외에도 인산화된 Erk 단백 등의 증가로 EGCG가 세포 생존을 지속시키 는 역할을 하고 있음을 알 수 있었다‘ 이러한 현상은 COS7 과 A549 세 포 에서 관찰되었으며 Hela 세포에서는 관찰되지 않아 세 포외부에서 EGCG가 결합하게 되 는 물질 혹은 세 포내 물질 등의 차이에 의해 세 포 미다 EGCG에 대한 반응이 다른 것으로 추측된다 24시간 이상 처리된 경우 ECCG가 세 포 생존에 관린된 인자들을 감소시키는 것으로 보아 EGCG에 처음에는 세 포 생존을 유도하지만 장시간 처리 시 세 포 증식 및 생존을 억제하는 물질 임 을 확인하였다.

In t his study, we tried to identify the key elements that respond to EGCG t reatment and its role in cell survival 0 1' apop tosis by EGCG. focusing on Akt pathway and Raf-MEK-ERK pathways. Cells were serum starved for 16 h and then treated with (-) -epiga llocatechin-3-gallate. To cletermine which pathway is related to effects of EGCG on cell s, the levels of phosphorylated Akt(pAkt) and Erk (pErk) were a nalyzed by immunoblotting. A549 cell s showed the increase of pAkt in response to EGCG‘ whereas Hela cells exhi bited no difference in the levels of pAkt by EGCG treatment Phos phorylation of Akt over initial basal levels became evident a fter 1 h of EGCG treatment and peaked at 3 h pErk was also increased by EGCG in Hela cells as well as in A549 cells To determine th e effect of EGCG on growth of cells‘ A549 cells were treated wi th vari 。u s concentrations of EGCG (from 10 μ M to 300 μ M) for 3 h. Cell growth was examined by MTI assay. The resulting growth curves of A549 cell s showed that EGCG promotecl cell prolifera tion in a close-dependent manner at early phase. When cells were t rea ted with EGCG for 24 h. pAkt and pErk expressions were significantly i띠1ibited ， even at 10 μ M B-raf ex pression was also clecreased in a close-dependent manner. In teresti ngly. the presence of serum weakened t his inhibitory effect of EGCG on the ex pression of survival facto rs. Our study inrucates that EGCG stimulates cell survival of A549 cells through thc PI3K/AKT pathway. though it fina lly be haves like a suppressive agent on cell su rvival

Body weight support treadmill training is a new and promising therapy in gait rehabilitation of patients with hemiplegia. The purpose of this study was to identify the effects of body weight support treadmill training on gait and standing balance in patients with hemiplegia. Eighteen patients with hemiplegia participated in the study. A 10 m-timed walk test, measurements of step length and standing balance score were administered. Intervention consisted of body weight support treadmill training five times a week for 2 weeks. The data were analyzed by paired t-test. Body weight support treadmill training scoring of standing balance, step length and 10 m-timed walk test showed a definite improvement. Body weight support treadmill training offers the advantages of task-oriented training with numerous repetitions of a supervised gait pattern. The outcomes suggest that patients with hemiplegia can improve their gait ability and standing balance through body weight support treadmill training.

The purpose of this study was to investigate the effect of knee exercises on the onset times of vastus medialis oblique muscle (VMO) and vastus lateralis muscle (VL) and in healthy subjects. Fifteen subjects (7 men, 8 women) in a mean age of 26.4 years participated in the study. Electromyographic (EMG) signals were recorded from the VMO and VL under four exercises. Knee exercises consisted of open kinematic terminal knee extension, straight leg raising, isometric hip adduction exercise, and closed kinematic terminal knee extension. No significant differences were found in the onset times of EMG activities of VMO and VL in the four exercises. There were also no significant differences among the exercises. These results coincided with previous studies that found no difference between onset of VMO and VL. However, it is difficult to say that there is no difference between onset of VMO and VL in healthy subjects. To confirm this results, further researches that follow same on set determination metod and exercises are needed. Not only is the study of onset time of muscle needed, but also the studies of the amount of activation and the rate of increase of muscle activation are needed.

Patients with hemiplegia usually show different body weight distribution as compared with normal subjects. Asymmetrical posture during static stance has been identified as a common problem in patients with hemiplegia. The purpose of this study was to identify the effects of vision and visual feedback on body weight distribution while standing under three conditions: eyes-closed, eyes-open and visual feedback condition. Fourteen patients with hemiplegia participated in the study. Their body weight distribution during standing for 20 seconds was measured by Limloader. The data were analysed by repeated measure of one-way ANOVA. The weight bearing on the paretic limb in the eyes-open condition was significantly higher than that of the eyes-closed condition. The weight bearing on the parietic limb in the visual feedback condition was significantly higher than that of the eyes-open condition. These results suggest that patients with hemiplegia can improve their symmetrical stance ability using visual feedback.