Background: The diaphragm release technique, commonly used in COPD patients, improves diaphragmatic mobility and inspiratory capacity. Diaphragmatic breathing, with slow deep breaths, supports autonomic regulation and benefits the brain, cardiovascular, and respiratory systems. However, research on their combined effects on respiratory function remains limited. Objectives: To investigate the effects of manual diaphragm release on respiratory functions, specifically focusing on forced vital capacity (FVC), forced expiratory volume in one second (FEV1), diaphragmatic mobility, and chest expansion. Design: A randomized controlled trial. Methods: The study involved 26 university students, who were randomly assigned to either the experimental group (Manual diaphragm release + Diaphragmatic breathing, MDR) or the control group (Diaphragmatic breathing, DB). Measurements taken before and after the immediate intervention included diaphragmatic mobility, chest expansion, FVC, and FEV1. Results: In the experimental group, significant differences were observed in diaphragmatic mobility, FVC, and FEV1 between the pre- and post-intervention measurements, while the control group had no significant changes. The experimental group showed significant improvements in diaphragmatic mobility and FVC compared to the control group. Conclusion: MDR significantly enhance diaphragmatic mobility and FVC in university students compared to DB. These findings suggest that MDR is an effective non-invasive intervention for improving specific respiratory functions.

If the release point of the precision air delivery system is determined only by L/D, target accuracy can be greatly reduced due to changes in wind speed and direction by altitude. In this paper, after conducting a self-made precision air delivery system (PADS) drop test, we analyzed the problems that may occur due to wind changes by altitude and proposed an algorithm to determine the release point of PADS to increase the precision of PADS landing. As a result of conducting the simulation with this algorithm, it was similar to the results of the drop experiment. In addition, the conceptual design of HW and SW was carried out for the actual dropsonde implementation in the future.

Background: Child care center teachers are exposed to musculoskeletal injuries caused by repetitive movements at low heights due to the nature of their jobs. Self-myofascial release (SMFR) improves flexibility, pain, and functional performance. Pectoralis minor self-stretching (PMSS) improves muscle flexibility and postural alignment. PMSS has been commonly used to correct a rounded shoulder posture (RSP). Objectives: To examine the shoulder height, muscle tone, muscle stiffness, and muscle elasticity for women child care center teachers with RSP. Design: Randomized study. Methods: The participants were 20 women child care center teachers with RSP. They were randomly assigned two groups: SMFR group (n=10) and PMSS group (n=10). They performed each exercise for 20 min, 3 times a week for 4 weeks. They measured shoulder height, muscle tone, stiffness, and elasticity of upper trapezius before and after exercise. Results: In the shoulder height, there was no significant difference between two groups. There were significant decreases within both groups. In the muscle tone, stiffness, and elasticity, there was no significant difference between two groups and within two groups. Conclusion: SMFR using a hard massage ball and PMSS have a positive effect on posture correction for child care center teacher with RSP.

In the present study, a novel pH-sensitive hydrogel composite of pectin-grafted-poly (acrylic acid-co-itaconic acid)/MWCNTs- COOH was prepared by using graft copolymerization of acrylic acid and itaconic acid on pectin backbone with incorporation of MWCNTS- COOH. The prepared hydrogel composite has been employed for the adsorption and controlled release of the diclofenac sodium (DS) drug. The hydrogel composite was characterized by the analysis methods: FTIR, XRD, SEM, and TGA to analyze structural characteristics before and after DS drug adsorption. The swelling ratio of the hydrogel composite was investigated at different pH values from pH 1.2 to 10. According to the results, the swelling ratio of the hydrogel composite was found 4195% at pH 7.4. Adsorption process parameters such as pH, contact time, adsorbent dose, and temperature were investigated and found to have a significant influence on DS drug adsorption. The maximum DS drug loading through adsorption of 91% was obtained at pH 3, adsorbent dose of 0.05 g, contact time of 150 min, and temperature of 15 °C. The adsorption isotherm and kinetic results were well-fitted to Freundlich and second-order models. Thermodynamic parameters including changes in Gibb’s free energy, enthalpy, and entropy suggested that the adsorption of DS drug onto hydrogel composite was a spontaneous and exothermic process. The in vitro drug release experiment showed that the cumulative release of DS drug from hydrogel composite after 35 h was significantly higher in simulated intestinal fluid at pH 7.4 than in simulated gastric fluid at pH 1.2.

노지 나방류 해충인 담배거세미나방 방제를 위한 유충기생성 천적 2종인 긴등기생파리와 예쁜가는배고치벌 의 방사조건을 확립하고자 콩 재배포장에서 방사거리 및 방사밀도별 기생율을 조사하였다. 긴등기생파리는 방사 후 24시간 이내 방사지점으로부터 10m까지 이동하여 나방류 유충을 기생하였으며, 예쁜가는배고치벌도 방사지점으로부터 15m에서도 기주유충에 산란하여 고치가 형성된 것이 확인되었다. 긴등기생파리는 면적당 방사밀도가 높아질수록 기생율이 증가했으며, ㎡당 0.15마리(천적:해충=1:5) 방사했을 때 평균기생율 63.1%로 나타났다. 예쁜가는배고치벌은 긴등기생파리와 같은 방사밀도에서 평균기생율 47.8%로 확인되었으나, 방사 밀도에 따른 기생율 차이는 없었다.

M. pruinosa has been found on 98 families and 345 species of plants, indicating a wide host range. Since its first report in a persimmon orchard in Gimhae in 2009, it had spread to 126 municipalities over 12,429 ha. Because of powerful dispersal ability, it’s difficult to control with insecticides. Therefore, it is necessary to reduce the population density through the release of M. pruinosa’s natural enemy, N. typhlocybae. N. typhlocybae females prey on or externally parasitize the nymphs of M. pruinosa. This natural enemy was introduced from Italy in 2017 through an international cooperative project between National Institute of Agricultural Sciences and University of Padova for controlling the sporadic pest, Metcalfa pruinosa. This study reported the results of mass rearing N. typhlocybae indoors and releasing them outdoors from 2020 to 2023 in 21 regions nationwide, showing an average parasitism rate of 27.3% and an average production of 7.9 cocoons per host, suggesting the possibility of their establishment in Korea.

Background: Self-myofascial release using a foam roller has short-term effects for improving muscle function and joint range of motion (ROM) and reducing delayed onset muscle soreness (DOMS) after exercise. Objectives: The purpose of our study was to examine the muscle physiological changes for each set in self-myofascial release of the hamstring muscles using a foam roller in order to provide basic data for the most effective program composition for improving muscle tension, stiffness, and flexibility of the hamstring muscles. Design: A quasi-experimental clinical trial. Methods: To confirm the effect of self-myofascial release of the hamstring muscles using a foam roller, muscle tone and stiffness of the hamstring muscles were measured. As an intervention method, the study subject performed four sessions of self-myofascial release by moving a foam roller back and forth on the posterior thigh muscle of the right leg. Results: There were statistically significant changes in the stiffness of the biceps femoris and the flexibility of the hamstring muscles. Conclusion: Self-myofascial release with foam rolling is an effective intervention method for increasing hamstring flexibility and ROM, and it is recommended as effective to perform self-myofascial release for three to four sessions to maintain normal muscle tone and stiffness of the hamstring muscles.

Sulforaphane is a naturally occurring active substance found in vegetables that is known for its potential in preventing and treating cancer. This compound has demonstrated promising effects in inhibiting the growth of various types of cancer, including esophageal, lung, colon, breast, and liver cancer. However, its instability towards pH and heat limits its application in the medical and food industries. To address this challenge, novel drug delivery systems have been developed to improve the stability and efficacy of sulforaphane, making it a more suitable candidate for clinical use in cancer research. In this study, nanocomposite materials were prepared using multi-walled carbon nanotubes (MWCNTs) and chitosan (CS) as base materials, with polydopamine (PDA) acting as a bridge material. The synthesized composite materials were used as drug carriers for the release of sulforaphane. The results of the study showed that the drug loading increased with an increase in the concentration of sulforaphane, indicating that the nanocomposite materials were effective in delivering and releasing the drug. Moreover, a positive correlation was observed between the drug loading and the thickness of the PDA layer. These findings suggest that the use of MWCNTs, CS, and PDA in the development of drug delivery systems can enhance the stability and efficacy of sulforaphane, potentially leading to improved cancer treatment outcomes.

아스팔트는 점성이 높은 도로포장 재료로서 골재와 채움재를 결합시키는 역할을 하는 중요한 재료이다. 아스팔트 콘크 리트는 생산 및 시공 과정에서 혼합물이 장비에 부착되는 현상이 발생하여 생산 효율 및 성능 저하를 유발하기도 한다. 이와 같은 문제를 해결하기 위하여 석유류와 식물성 기름을 부착방지제(Asphalt Release Agent)로 사용하고 있다. 하지 만 석유류는 단시간에 아스팔트를 용해시켜 혼합물의 성능 저하를 유발할 수 있고, 발생하는 유증기로 인해 작업자를 위 험에 노출시킬 수 있다. 식물성 기름은 석유류에 비해 아스팔트에 대한 용해력은 다소 작지만 석유류와 동일한 문제를 야기하며 제품 단가로 인해 높은 비용을 발생시킨다. 이에 따라 아스팔트 혼합물 생산 및 시공현장에서 저독성이며 친환 경적인 부착방지제의 중요도가 상승하고 있다.

A semi-natural composite of κ-carrageenan and bentonite, two natural biopolymers, was synthesized through free radical polymerization. This synthesis aimed to obtain a biodegradable, biocompatible, and swellable composite that is environmentally friendly. The components used in this synthesis are readily available, making it economically feasible and promising for potential biomedical applications. The composite is pH-responsive and intended for oral delivery of metformin hydrochloride and aminophylline, which have low bioavailability and undesirable side effects, respectively. The organic composite exhibits the advantage of reducing drug release in the acidic gastric medium. This composite is a stimuli-responsive polymeric material that has garnered significant attention in recent years for its application in oral drug delivery systems. These materials enable site-specific and controlled drug release while minimizing toxicity. The carrageenan-g-poly(acrylamide-co-acrylic acid)/bentonite composite was characterized using Fourier transform infrared (FTIR) spectroscopy, X-ray diffraction (XRD), transmission electron microscopy (TEM), and field emission scanning electron microscopy (FE-SEM), which confirmed the successful synthesis of the composite. The swelling behaviour and point of zero charge of the composite were studied at different pH values, which showed a strong influence on the swelling properties of the composite. The drug loading capacity of the composite was measured at pH 5.3, and it was 70.60 mg/g for metformin and 95.66 mg/g for aminophylline at pH(3). The in vitro release profile of both drugs from the composite was also affected by the ionic strength, and it exhibited a lower release rate with higher salt concentration. The maximum release percentage of the drugs from carrageenan-g-poly(acrylic acid-acrylamide)/bentonite in simulated gastric, intestinal, and colon fluids was achieved within 40 h. The maximum release was 80% for metformin in simulated intestinal fluid (SIF) and 75% for aminophylline after 40 h.

모바일 게임 시장 규모가 시간이 지날수록 커지고 있다. 그만큼 한국뿐만 아니라 전 세계적으로 모바일 게임 을 개발하고 출시하고 있는 개발사들이 늘어나고 있는데, 한해 출시되는 수백 개 이상의 모바일 게임들 사이 에서 성공적으로 유저들을 유치하고 수익을 창출하기 위해서는 단순히 모바일 게임을 완성도 있고 재미있게 개발하는 것으로 끝나는 것이 아닌 출시 이전부터 출시 이후 운영 까지 다양한 개발 외적인 전략을 활용하여 경쟁력을 확보해야 한다. 본 연구에서는 모바일 게임의 완성도를 결정하는 게임 내적인 요인들을 제외하고 출 시, 마케팅, 운영 등 모바일 게임 개발 외적인 요인들 중 모바일 게임의 성공에 도움이 될 수 있는 키워드들 을 추출하고 이에 대한 전략들을 정의함으로써 향후 모바일 게임 개발사들이 게임을 개발하는데 있어 참고할 수 있도록 하였다.

일본 정부는 2021년 4월 13일 일방적으로 후쿠시마 원전 오염수를 해양에 방 류하기로 결정했다. 일본의 원전 오염수 해양 방류는 후쿠시마 주변 해역 및 연안의 해양환경에 미치는 방사능 오염뿐만 아니라 우리나라 연안과 태평양 전 역으로 방사능이 유입되어 피해가 발생할 수 있으며, 해양 생태계 변화 등의 심각한 문제도 발생할 것이다. 일본의 원전 오염수 방류 결정에 대한 다양한 대응 방안이 검토되고 있으며, 유엔해양법협약을 중심으로 국제해양법재판소 제소 및 심각한 피해의 가능성과 상황의 긴급성이 있는 경우 잠정조치 신청도 할 수 있다. 이 논문에서는 일본의 원전 오염수 방류 결정에 대한 문제점을 살펴보고, 해 양환경 오염으로 인한 국제환경분쟁의 의의와 주요 특성에 관한 내용을 검토하 고, 소송에 대비하여 유엔해양법협약 관련 규정 및 판례들을 검토하여 시사점 을 도출하였다. 일본의 후쿠시마 원전 오염수 방류가 임박한 시점에서 문제 해 결을 위하여 최우선으로 유엔해양법협약을 근거하여 ITLOS 제소 및 잠정조치 신청을 하는 사법적 해결방안을 모색하고 동시에 한일 양국 간 또는 국제사회 의 공동 협력체계를 통한 외교적(비사법적) 해결방안 등 실효적인 해결방안을 제시하고자 한다.

The anaerobic digestion process produces methane while stabilizing sludge. As of 2020, 62 anaerobic digesters in public wastewater treatment plants are operational in Korea. Many researchers have studied to improve digester performance. Thermal hydrolysis technology is one of the pre-treatment methods for treating sludge. Reduced retention time and enhanced biogas production are the main advantages of sludge disintegration at relatively high temperatures and pressures. But nutrients like nitrogen and phosphorus are released from the pre-treated sludge. Phosphorus is a non-renewable resource that is essential to food production. Wastewater receives 20% of the total phosphate discharge, while 90% of the influent phosphorus load is in sludge. For efficient phosphorus recovery, it is essential to comprehend the phosphorus release characteristics during wastewater treatment, including anaerobic digestion. Biological or chemical processes can achieve phosphorus removal to comply with the effluent discharge limits regulations. The three primary sources of phosphorus in sludge are aluminum-bound phosphorus (Al-P), polyphosphate in phosphorus-accumulating organisms (PAOs), and iron-bound phosphorus (Fe-P). Anaerobic digestion is the typical method for recovering carbon and phosphorus. However, previous research has demonstrated that most phosphorus in anaerobic digestion occurs as a solid phase coupled with heavy metals. Therefore, the poor mass transfer rate results in a slow phosphorus release. Due to the recent growth in interest and significance of phosphorus recovery, many researchers have studied to improve the quantity of phosphorus released into the liquid phase through chelation addition, process operation optimization, and disintegration using sludge pre-treatment. The study aims to investigate characteristics of the phosphorus release associated with the thermal hydrolysis breakdown of sludge and propose a method for recovering phosphorus in a wastewater treatment plant. When solubilizing sludge using thermal hydrolysis pre-treatment, organic phosphates, inorganic phosphates, and polyphosphates are converted into ortho-phosphate. Therefore, applying thermal hydrolysis, anaerobic digestion, and phosphorus recovery processes (struvite formation or microbial electrolysis cells) can recover carbon and phosphorus.

Background: The muscles associated with tension-type headache (TTH) are connected to the scalp fascia, which is firmly attached to the superciliary ridge of the frontal bone. However, there is a paucity of data on treatments for TTH that directly target the scalp fasciae. Objectives: We aimed to validate a new manual therapy to treat TTH by applying myofascial relaxation techniques to the scalp and to examine the changes in quality of life and headache characteristics after treatment. Design: pretest-posttest control group design study. Methods: Total 24 participants with TTH (10 males, 14 females) participated in the study. Manual therapy group (MT) received standard manual therapy and scalp myofascial release technique group (SMT) received scalp myofascial release technique twice per week for 4 weeks. Brief Pain Inventory (BPI) and Headache Impact Test (HIT) for quality of life, headache frequency, duration, and Visual Analog Scale (VAS) for intensity were assessed at the pre- and post-treatment. Results: There was a significant improvement within groups in headache frequency (MT P<.05, SMT P<.001), duration (MT P<.05, SMT P<.01), VAS (MT P<.01, SMT P<.001), HIT (MT P<.001, SMT P<.001), and BPI (MT P<.001, SMT P<.001) between the pre- and post-treatment. Group differences were significant for headache duration (P=.027), but the others were not. MT and SMT reduced the impact of headaches on daily life. Also Headache frequency, duration, intensity, and BPI were improved. Conclusion: MT and SMT reduced the impact of headaches on daily life. Also Headache frequency, duration, intensity, and BPI were improved. It has been suggested that both MT and SMT can be used as a non-invasive treatment to treat the TTH, and to improve the quality of life.