Because multiple ovulation embryo transfer (MOET) in cattle includes several benefits such as wide spreading of genetically superior offspring for long distance, this biotechnological method has been widely applied to Hanwoo. When the recipients are not stayed close after embryo recovery from donor, the embryos are moved to other farms via several vehicles (car, train, and airplane). However, air travel induces lesser oxygen level, increased vibration, lower air pressure, higher noise, and increased exposure of cosmic radiation to living things than ground level. It was still unknown that fresh embryos obtained from multiple ovulation of Hanwoo could maintain their fertility after being transported via air plane, the present case report introduced a clinical case of MOET in Hanwoo after shipping fresh embryos via air transportation. The donor was multi-ovulated via follicle-stimulating hormone series of injection, which was followed by a gonadotrophin-releasing hormone injection and artificial insemination twice. The embryos were recovered by the uterine flushing, packed in ministraws, transported to recipients for 6 h including 1 h air flight, and then transferred to the synchronized recipients. During pregnancy diagnosis of early gestation period, 5 of 7 recipients (71.4%) presented no heat signs and showed fetal sacs with fluid under transrectal ultrasonography. After normal gestation period, all recipients naturally delivered healthy calves (male n = 2 and female n = 3) without abortion, stillbirth, and premature birth. The present case report indicated that transportation of fresh embryos for MOET via domestic flight in Korea did not affect to their fertility.
Multiple endocrine neoplasia type 2B (MEN2B), which is an autosomal dominant hamartoneoplastic syndrome, is a genetic syndrome. Patients with this syndrome are characterized by multiple mucosal neuromas on the tongue, lips, eyelid margins, and conjunctiva with marfanoid habitus, thick and protruding lips, open bite, and maxillary central diastema. Multiple oral mucosal neuromas are known to appear before the development of medullary thyroid carcinoma (MTC) or pheochromocytoma. Therefore, understanding the oral symptoms is very important for the early diagnosis of this syndrome. We report multiple submucosal neuromas in a 19-year-old male patient diagnosed with MEN2B and review this syndrome.
비즈니스 선교의 용어와 개념이 세상에 소개된 지 20년이 되었고, 한국 선교계에 소개된 지 12년이 지났다. 새로운 선교 환경의 패러다임 에 적절히 대응할 수 있는 선교적 접근으로 비즈니스 선교를 구체적으로 고려할 때가 되었다. 이 연구는 다수 사례 연구로서, 힌두권의 한 도시에서 행해진 비즈니스 선교 사례들을 정리하고 분석했다. 이 연구 의 사례들은 모두 소규모의 비즈니스 선교 사례들이다. 이 연구의 사례들에서 발견한 점들은 다음과 같다. 초기 수년의 기간을 사업에 집중했을 때 사업의 매출 증대 뿐 아니라 안정화에 크게 도움을 주었다. 생존기에 시장과 고객에 신속히 적응하려고 노력하면 기업의 생존 가능성이 높아진다. 모든 사례들이 현지인을 주 고객으로 삼았다. 비즈니스 선교사들이 자신의 사역에 대해 전문 지식 없이 막연한 기대를 가지고 있었지만 유사한 지식이나 경험을 가졌고 전문가와 후원자들의 도움을 적극 받아들였다. 선교사들의 비즈니스 선교에 대한 이해에 따라 이들의 사역이 달랐고 사업의 성장도 다르게 나타났다.
Dentigerous cysts, the most commonly occurring developmental cysts of the jaw, develop in association with impacted teeth. Most dentigerous cysts are solitary. Multiple dentigerous cysts are rare and generally occur in association with a developmental syndrome or systemic disease, such as mucopolysaccharidosis and cleidocranial dysplasia. However, in the absence of a syndrome, occurrence of multiple dentigerous cysts is rare. Development of multiple dentigerous cysts on first molars extremely rare. The purpose of this paper was to report on a nonsyndromic, 8-year-old boy who presented multiple dentigerous cysts on first molars.
융모막암은 임신과 연관되어 융모막조직이 비정상적으로 성장하는 종양으로 난소, 고환, 자궁 등 생식기관에 주로 발현 되며 주변장기로의 침범이나 원격전이를 잘하는 특징이 있다. 융모막암이 생식기관이 아닌 장기에서 발생하는 경우는 매우 드물며 대부분 나쁜 예후를 보인다. 저자들은 중년 여성에서 급성 췌장염과 뇌출혈로 발현되고 다발 장기전이를 동반한 췌장 융모막암 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다.
본 증례는 다발성 골수종을 진단 후 Bortezomib, Melphalan, Prednisolone 항암치료 중에 급성 췌장염이 발생된 매우 드문 경우이다. 급성 췌장염이 원인을 알기 위하여 알코올 병력, 담석증, 외상, 고칼슘혈증, 고중성지방혈증 등에 대한 혈액검사 및 영상의학적 검사를 시행하였지만 특별한 소견은 없었다. 급성 췌장염을 유발할 수 있는 약제인 Bortezomib이 그 원인일 가능성으로 판단되어 Bortezomib 중단과 보존적 치료로 급성 췌장염이 호전되었다. Bortezomib은 다 양한 비특이적인 위장관 증상을 흔하게 유발할 수 있지만 복통이 지속되거나 재발하면 드물지만 급성 췌장염이 발생할 수 있음을 염두에 두어야 하겠다.
The effectiveness of monetary policy critically depends upon how well the transmission mechanism functions, so that the desired impact on output and inflation is achieved. The purpose of this paper is to study the transmission mechanism of monetary policy by analyzing the impact on inflation and output during multiple indicator regime (1998-99 to 2014) in an emerging economy-India. The Inflation Targeting Regime is also briefly outlined alongwith the impact on output and inflation. Using quarterly data for the period 1997 to 2017, the paper uses weighted average call money market rate as a proxy for the policy rate and evaluates the strength of the interest rate channel. We use a conventional Structural vector auto regression (SVAR) methodology to evaluate the efficacy and show the impluse response functions. Our results find that changes in the policy rate impact output growth steeply with a lag of about two quarters and the impact on inflation is maximized after three quarters. The study concludes that the monetary policy in India has a significant impact on output and inflation in the short-to-medium-run. After the policy shock, the fall in the output growth rate is of greater magnitude than the fall in inflation.
Pulmonary embolism (PE) still has a high associated mortality. Anticoagulation should be continued until the benefit of preventing recurrent PE is outweighed by the risks of bleeding. Furthermore, D-dimer values and residual clot burden may predict recurrent thromboembolic events in patients that have completed anticoagulation therapy. The authors describe the case of a 69-year-old female who suffered multiple recurrent PE on aspirin, her medical history included idiopathic PE, and she had been on anticoagulant for a considerable time before switching to aspirin. It is important the possibility of recurrent PE be borne in mind to prevent secondary prevention, and that other treatment options be considered in cases of recurrent PE.
In rural planning, the cost estimation of project is a key factor for planning. Therefore, development of reliable cost estimation method is essential. Recently, new techniques are suggested for determination of project cost using historical cost data. In this study, a multiple-regression analysis was used to determine the cost of the farm land consolidation. The results demonstrated that multiple regression analysis using historical cost data can be applicable to project cost estimation.
Recently recognize the labor productivity of port physical distribution system in the port and shipping areas, Much Efforts for evaluating this productivity has been made continuously. BUt still there is little study, so far, on a systematic research for the management of port labor gangs, and even those were mainly depended on a rule of thumb. Especially the object of this study is to introduce the method of optimal allocation and assignment for the labor gangs per pier unit in the multiple ships berthed at an arbitary pier or port. In case the multiple ships have a homogeneous cargoes or do not have sufficient labor gangs to be assigned. The problem of optimal allocation and assignment of the labor gangs to be i) formalized with multi-state decision process in form of difference equation as the pattern which converted the independent multiple ships into a single ship with the intra-multiple ships, and ii) the optimal size of labor gangs could be obtained through the simple mathematical method instead of complicated dynamic programming, and iii) In case of shortage of labor gangs available the evaluation function considering the labor gangs available and total shift times was introduced, and iv) the optimal allocation and assignment of labor gangs was dealt at the point of minimizing the summation of the total shift times and at the point of minimizing the total cost charged for the extra waiting time except PHI time during port times for the multiple ships combinations.