본 논문에서는 가상환경하에서 사용자가 느끼는 물체의 무게감에 관해 연구하며, 3D mouse에 스프링의 탄성력을 이용한 근력입력장치를 새롭게 디자인한다. 근력입력장치는 몰입형 가상환경에서 사용자들의 악력을 이용하여 힘이나 무게를 느낄 수 있도록 고안된 장비이다. 본 논문에서는 물체의 부피와 무게감에 관한 실험, 물체의 재질과 무게감에 관한 실험, 근력입력장치의 악력과 무게감에 관한 실험 등 세 가지 실험을 수행하여 비교·분석한다. 실험결과의 통계적 분석 및 사용자 설문지 분석을 통해서 얻은 결론은 몰입형 가상환경하에서 부피와 재질은 사용자들에게 현실감 있는 무게감을 느끼는 데 중요한 역할을 하지 못하지만, 근력입력장치의 악력을 사용할 경우 현실감을 증대시키며 무게감을 느끼는 데 중요한 역할을 한다. 본 연구에서 제안한 근력입력장치는 무게감을 제공하는 데 효과적이다.
Growing evidence indicates that oxidized low density Iipoprotein (LDL) may promote atherogenesis. Therefore, inhibition of LDL oxidation may impede this process. The effect of chitin sulfate on the susceptibility of human low density lipoprotein (LDL) to macrophages-induced oxidation was investigated by monitoring a thiobarbituric acid reactive substance (TBARS). Chitin sulfate inhibited LDL oxidation by macro phages in a dose dependent manner, with a 50-100μM, as assessed by TBARS assay. Chitin sulfate, at 100 μM, almost completely inhibited the macrophage-induced increase in electrophoretic mobility of LDL. Also, chitin sulfate almost completely inhibit O₂^- at concentration of 100 μM. These observations suggest that chitin sulfate might be an effective in prevention of atherosclerosis.
Human factor를 고려한 콘택트 렌즈에서 UV-A, UV-B 선 차 l잔 효융을 평가하기 위해 투과율에 의한 가시광 영역 Iuminance와 luminance에 의한 동공크기를 분석하였 다. Lur띠nance(L)에 따른 동공크기 (φ) 는 φ=d-e . tanh(f . IogL)로 주어지고, 동공 크 기 (r) 에 따른 투과효용은 Tr(r)=1-gr2 +hr4으로 human factor가 주어진다. 320-4oonm 파장 영역인 UV-A에 대한 절대 차단 효율 a와 제거 지수 b=(l-a) x 100%를 유도하 였다. RGP, CL(A), CL(m 둥의 sample에서 UV-A 에 대한 a 값은 0.91, 0.93, 0.90이며 b 값은 9, 7, 10 이었으며, UV-B 에 대한 a 값은 0.84, 0.95, 0.97 이며 b 값은 16, 5, 3 이었고, UV-C 에 대한 a 값은 0.17, 0.35, 0.42 이며 b 값은 &'3, 65, 58을 각각 얻었다.
This study was performed to evaluate whether vitrification method using ethyle glycol and eletron microscopic (EM) grid could be used far the cryopreservation of human oocytes in ART program. Surplus oocytes were obtained from consented IVF patients. These surplus human oocytes were frozen with our vitrification method, Oocytes were exposed to 1.5M ethylene glycol (EG) in DPBS far 2,5 minutes, followed by 5.5M EG plus 1.0M Sucrose in DPBS for 20 seconds. Then oocytes were transferred onto the EM grid and the grid was plunged into LN2 for storage. For thawing, oocytes containing EM grid were sequentially transferred in 1.0M, 0.5M, 0.25M, 0.125M and 0 M sucrose in DPBS solution at the intervals of 2.5 minutes. Thawed and survived oocytes were provided for ICSI. Embryos from vitrified oocytes were transferred to uterus of the patient on 4 to 5 days after ovulation in natural cycles of on 15 to 17 day of hormone replacement cycles. A total of 370 oocytes from 26 patients were thawed and 159 (43.0%) of them survived. One hundred thirty four oocytes (84.3%) were fertilized normally and 126 pre-embryos were transferred to 26 patients, resulting in 5 clinical pregnancies. The pregnancy rate per transfer was 19.2% and implantation rate was 4.0%. Among the five pregnant, 4 patients delivered 4 healthy babies and the one patient was 32-week ongoing pregnancy. From this results, vitrification using ethylene glycol as cryoprotectant and EM grid is a rapid and simple method that can be effectively applied for the cryopreservation of human oocytes in ART program.
본 연구는 안과에서 주로 사용되는 생체 염색시약으로 Fluorescein, Rose Bengal, Erythrosin B, Lissanúne Green B 올 인간의 결박세포인 Clone1-5c-4 cell line올 배 양하여 cytotoxicity릎 조사하기 위하여 1%, 0.25% 의 농도보 5분, 15분 동안 처리하 여 MTT assay, SRB assay를 실시하였다. 각 염색사약의 세포독성올 바교 검정한 결과, Rose Bengal과 Lissamine Green B에서 서I 포 증식 저해용이 30% 이상 나타났 고, 회복효과를 보기 위하여 시약 제거 후 1 일 배양하여 Ml‘T. SRB assay를 실시한 결과는 Rose Bengal에서 거의 비슷한 수준이었으나 Lissamine Green B 에서는 더 증 가하였다. 또한 5, 15분 동안 시약처리 직 후 subculture활 실시한 후 세포의 부착과 중식정도를 관찰하였고, 회복효과를 보기 위해 3 잊 후에 세포의 형태를 관찰한 결과, Rose Bengal은 거의 차이 가 없었으나 Fluorescein 에서는 회복효과를 보였다.0.25% trypsin을 처리하여 세포에 영향을 주어 세포의 인위적인 손상올 형태학적으로 비교 한 염색상 세포 저해 정도는 Rose Bengal 이 가장 높-았고, Fluorescein 이 제일 낮았 다. 이러한 결과로 볼 때 일부 생체 염색시약이 인간의 결막세포인 Clone1•5c -4 세 포증식을 저해하는 것으로 사료된다.
Through his long poetic career from 1885 to 1939 Yeats was preoccupied with the dualistic nature in this world―the ideal against the real, body against soul, and Self against Anti-self. He was aware that these conflicts and contradictions were necessary for the mental growth in man and through the struggles between these opposites he might achieve the state of the whole. In his attitude toward life Yeats embraced with open mind both what he was and what he wanted bo be. The two opposites are co-existent and inseparable so as to be united into the Whole Being. Yeats had applied the symbols of ‘sexual union’ and ‘dance’ to his poetry in order to express ecstatic experience of ‘Unity of Being.’ This paper traces up Yeats’s attitudes toward life, and studies the aspects of conflicts and contradictions, through which he may attain the ‘Unity of Being,’ the ideal that Yeats had searched throughout his poetry and other activities.
Work-related injurieshave become the issue in the twentieth century. Musculoskeletal disorders are the most common work-related injuriesand the most frequent from of work-related i11-health (more than 50% of total work-related injuries (BLS 1990)). The workers at copy shops have complained of pain in their back, legs, and shoulders. Most of them work for more than 8 hours a day. They have claimed that their pains were associated with repetitive and continuous work over a long term. The purpose of this research is to suggest an ergonomically comfortable redesign of the copy machine. This study was performed by conducting a survey of copy shop workers who have complained of job-related physical pain, and analyzing their working postures. The copy machine was ergonomically modified to reduce the workers' pain. The VIS10N 3000 software was used to analyze the posture. The analysis showed significant difference in the ranges of back and neck motion (p<0.05).
The model of human occupation is an outgrowth of the occupational behavior tradition which emphasizes the original philosophical premises of the occupational therapy profession. The model employs general systems theory to explain the human system and its interaction with the environment. The model conceptualizes the human as an open system that consists of three subsystems: volition, habituation, and mind-brain-body performance. The subsystems are hierachically ordered from the highest to lowest and each subsystem has its own structure and function. The highest subsystem is referred to as volition which is responsible for freely and consciously choosing occupational behavior. The middle subsystem is habituation which organizes occupational behavior into patterns or routines. The lowest subsystem is mind-brain-body performance which makes possible the skilled achievement of occupations. The human is also understood as a dynamical system performing in an environment composed of objects, tasks, social groups, and culture. Although the language of the model may be unfamiliar at first the basic theoretical principles of the model share the common concept with those of the oriental philosophy. The model is recognized as a holistic and comprehensive model which is one of the first to develop a strong focus on occupation in the occupational therapy profession.
This paper described the effect of subjective approach in case of the human sensibility experiments. The procedure is proceeded subjectively. Human faces are selected as the image presentation media. Pleasant and unpleasant images are selected directly by examiner, And also the image presentation system, which is executed with a computer and has the square-type black box monitor equipment, is manufactured. Images are presented with the step-variation time interval technique. questionnaire test and EEG signal detection data are analyzed. The analysis parameters are a “frequency band integral value” and a “band differential variation ratio”. he results show the high sensibility and fast response. The fact that image presenting repetition alleviates is verified.
When consumer evaluates a product, every aspec of the product affects the evaluation. Human uses at least five sensory organs for the evaluation. Multi-sensory or multi-modal design tries to add auditory and olfactory factors to the traditional visual-centered design. For the multi-modal design, it is essential to understand relationships between combined sensory stimuli and human sensibility. Information between simple sensory stimulus and human sensibility is pre-requisite to combine multi-modal stimuli. This study investigated human sensibility against 8 colors and 30 sounds, presented independently. The combined stimuli of color and sound were made based on the sensibility generated by each stimulus. Human sensibility generated by the combined stimuli of color and sound were made based on the sensibility generated by each stimulus. Human sensibility generated by the combined stimuli was investigated with 20 female subjects. For combined stimuli that generated the same kind of sensibility respectively, generated sensibility was same but strength was diminished. For combined stimuli that generated the different sensibilities respectively, subjects showed neutral sensibility or no special sensibilities. Sensibilities to the same stimuli also showed difference depending on personal background of the subjects.