The Spectro-Photometer for the History of the Universe, Epoch of Reionization and Ices Explorer (SPHEREx) will provide all-sky spectral survey data covering optical to mid-infrared wavelengths with a spatial resolution of 6.′′2, which can be widely used to study galaxy formation and evolution. We investigate the galaxy-galaxy blending in SPHEREx datasets using the mock galaxy catalogs generated from cosmological simulations and observational data. Only ∼0.7% of the galaxies will be blended with other galaxies in all-sky survey data with a limiting magnitude of 19 AB mag. However, the fraction of blended galaxies dramatically increases to ∼7–9% in the deep survey area around the ecliptic poles, where the depth reaches ∼22 AB mag. We examine the impact of the blending in the number count and luminosity function analyses using the SPHEREx data. We find that the number count can be overestimated by up to 10–20% in the deep regions due to the flux boosting, suggesting that the impact of galaxy-galaxy blending on the number count is moderate. However, galaxy-galaxy blending can marginally change the luminosity function by up to 50% over a wide range of redshifts. As we only employ the magnitude limit at Ks-band for the source detection, the blending fractions determined in this study should be regarded as lower limits.

A force-free field (FFF) is determined solely by the normal components of magnetic field and current density on the entire boundary of the domain. Methods employing three components of magnetic field suffer from overspecification of boundary conditions and/or a nonzero divergence-B problem. A vector potential formulation eliminates the latter issue, but introduces difficulties in imposing the normal component of current density at the boundary. This paper proposes four different boundary treatment methods within the vector potential formulation. We conduct a comparative analysis of the vector potential FFF solvers that we have developed incorporating these methods against other FFF codes in different magnetic field representations. Although the vector potential solvers with the new boundary treatments do not outperform our poloidal-toroidal formulation code, they demonstrate comparable or superior performance compared to the optimization code in SolarSoftWare. The methods developed here are expected to be readily applied not only to force-free field computations but also to time-dependent data-driven simulations.

Background: The Nordic hamstring exercise is effective as a representative exercise for strengthening eccentric contraction that can activate the hamstring at high levels, improve eccentric contraction strength and ability, and significantly reduce injury rates. Objectives: To investigated a comparison with the lunge exercise to determine the effect of the Nordic hamstring exercise on muscle activity and balance ability in a sample of adult amateurs and football players. Design: Randomized controlled trials. Methods: The subjects of the study were stratified samples of 28 professional and amateur football players and two groups (Nordic hamstring group and lunge group) of 14 people each were studied. Surface electromyography using, was performed to measure the hamstring muscle activity, and the good morning exercise was selected as the measurement exercise. For balance ability, the surface area ellipse and length were measured with BioRescue, while for static balance, the posture of closing the eyes and single-limb standing was measured, and for dynamic balance the one-legged squat was measured. Results: The %MVIC of the semitendinosus and the biceps femoris improved in the Nordic hamstring exercise group and showed statistically significant increase (P<.05). The static and dynamic balance improved in the Nordic hamstring exercise group and showed statistically significant decrease (P<.05). Conclusion: The Nordic hamstring exercise can be useful as an exercise to improve the hamstring muscle activity and balance ability of professional and amateur football players.

해사영어는 선박 운항, 해양 안전, 선내 의사소통 및 선외 교신을 위해 설계된 특수한 영어 언어체계이다. 국제해사기구 STCW(선원의 훈련, 자격증명 및 당직근무의 기준에 관한 국제협약)에 따르면 국제항해에 종사하는 항해사가 되기 위해서는 SMCP를 포함한 해사영어 대한 충분한 이해가 수반되어야 한다. 본 연구는 음성인식, 번역, 단어 기입 등 유형의 해사영어시험을 통하여 학생들 의 해사영어 활용 능력을 측정하고 플랫폼 사용에 따른 시험 점수 향상 정도, 나아가 초임항해사로 나가기 위하여 요구되는 해사영어 시험 플랫폼 활용 시간 등을 조사하고자 하였다. 실험은 먼저 초기 시험을 통해 학생들의 일반영어능력과 SMCP 활용 능력에 대한 연 관성을 조사한 후, 중간 시험 및 최종 시험을 통해 플랫폼 활용에 대한 점수 향상 정도, 응시시간 변화 등 요인을 측정하였다. 초기 시 험을 통해 개인 요인(예: 토익 점수, 본인 스스로에 대한 영어능력 평가)에 따른 그룹 간 해사영어시험 점수에 유의한 차이가 있음을 확인하였으며, 중간시험 및 최종시험을 통해 플랫폼 활용이 유의한 시험점수 향상으로 이어졌음을 확인하였다. 해당 연구는 해사 교육 분야에 다양하게 적용할 수 있는 학습 플랫폼 활용 효능을 조사하였으며 향후 해사영어 교육 외 그 범위를 넓혀 활용될 수 있을 것으 로 사료된다.

Along with other heavy metals, arsenic (As) is one among the substances most harmful to living organisms including humans. Owing to its morphological similarity to phosphorus, the uptake of As is influenced by photosynthesis and the phosphorus uptake pathway. In this study, we varied arsenic exposure and light intensity during nutrient solution cultivation of lettuce (Lactuca sativa L.) to determine the effect of these two factors on arsenic uptake, lettuce growth, and electron transfer in photosystem II. In the treatment exposed to 30 μmol L-1 of arsenic, the shoot arsenic concentration increased from 4.73 mg kg-1 to 18.97 mg kg-1 as the light intensity increased from 22 to 122 μmol m-2 s-1. The water content and ET2o/RC of the shoots were not affected by arsenic at low light intensity; however, at optimal light intensity, they decreased progressively with arsenic exposure. Increased light intensity stimulated the growth of plant roots and shoots; contrarily, the difference in growth decreased as the concentration of As exposure increased. The results of this study suggest that the effect of As on plant growth is dependent on light intensity; in particular, an increase in light intensity can increase the uptake of As, thereby affecting plant growth and As toxicity.

Hypertension is characterized by excessive renin-angiotensin system activity, leading to blood vessel constriction. Several synthetic compounds have been developed to inhibit renin and angiotensin-converting enzyme (ACE). These drugs often have adverse side effects, driving the exploration of plant protein-derived peptides as alternative or supplementary treatments. This study assessed the phenolic compound and amino acid content and the antioxidant and antihypertensive activity of 5 South Korean staple crops. Sorghum had the highest phenolic compound content and exhibited the highest antioxidant activity. Millet grains, particularly finger millet (38.86%), showed higher antihypertensive activity than red beans (14.42%) and sorghum (17.16%). Finger millet was found to contain a large proportion of branched-chain, aromatic, and sulfur-containing amino acids, which are associated with ACE inhibition. In particular, cysteine content was positively correlated with ACE inhibition in the crops tested (r=0.696, p<0.01). This study confirmed that the amino acid composition was more correlated with the antihypertensive activity of grains than the phenolic compound content. Finger millet mainly contained amino acids, which have higher ACE inhibitory activity, resulting in the strongest antihypertensive activity. These findings underscore the antihypertensive potential of select crops as plant-based food ingredients, offering insight into their biological functions.

The present study describes Philodromus paiki sp. nov., which was previously misidentified as P. fuscomarginatus (De Geer, 1778), P. poecilus (Thorell, 1872), and P. spinitarsis Simon, 1895 in Korea, as a new species with diagnosis, detailed descriptions, and taxonomic photographs. Additionally, P. spinitarsis is also described to correct previous misidentifications of Korean records of the species.

Abstract Purpose : The distribution of axial length and ocular dimensions was investigated, and each correlation according to gender and age was investigated. Methods : Among 847 eyes of 438 patients, 207 eyes in 20s, 210 eyes in 30s, 216 eyes in 40s, and 214 eyes in 50s were measured for axial length with IOL-Master 700. Refractive error was measured with KR-800. Corneal curvature radius and corneal eccentricity were measured with Keratograph 4. Results : Axial length (male: 24.57±1.22mm, female: 24.03±1.12mm) and horizontal corneal eccentricity (male: 0.58±0.11, female: 0.54±0.12) tended to increase in decreased age, male and myopia. Mean corneal curvature radius (male: 7.82±0.25mm, female: 7.71±0.25 mm), and horizontal corneal curvature radius (male: 7.91±0.26 mm, female: 7.79±0.26mm), nasal corneal eccentricity (male: 0.68±0.14, female: 0.66±0.15), and temporal corneal eccentricity (male: 0.45±0.14, female: 0.44±0.13) tended to increase in decreased age and male. Mean corneal eccentricity (male: 0.57±0.12, female: 0.54±0.12), vertical corneal curvature radius (male: 7.71±0.27 mm, female: 7.65±0.24 mm), vertical corneal eccentricity (male: 0.56±0.15, female: 0.54±0.15), and inferior corneal eccentricity (male: 0.52±0.19, female: 0.46±0.22) tended to increase in male. The correlation with axial length and corneal curvature radius showed a high correlation in emmetropia and the horizontal. Horizontal and temporal corneal eccentricity showed a low correlation. Conclusion : Axial length, corneal curvature radius, and corneal eccentricity (excluding vertical) were higher in males. As age increased, axial length, and corneal curvature radius decreased. Among the 4 quadrants of corneal eccentricity, only the temporal s ide showed a significant correlation with axial length. Key words : Age, Axial length, Corneal curvature radius, Corneal eccentricity, Gender Authors ORCID:†

Abstract Purpose : The aim of this study was to identify knowledge and lifestyle habits for glaucoma prevention and to present basic data for future glaucoma prevention education. Methods : From April to September 2023, 447 people in their 20s to 60s were selected and an online survey was conducted. The questionnaire consisted of a total of 30 questions, including 6 questions about the subject's general characteristics, 14 questions about knowledge and awareness of glaucoma, and 10 questions about lifestyle habits related to intraocular pressure. Results : 89.7% responded that they had heard of glaucoma, and 31.1% of respondents knew the difference between glaucoma and cataracts. 34.5% responded that early detection is difficult, 33.3% that complete treatment is difficult, 23.5% that even normal intraocular pressure can cause glaucoma, and 36.0% that the incidence of glaucoma is increasing day by day. The level of awareness and knowledge was higher with age, in women than men, in those with a family history, in professional occupations, with metabolic diseases, and with high myopia. Lifestyle habits related to intraocular pressure were higher with age, among women, when smartphone use was less than 3 hours, and among housewives and professionals. The relationship between glaucoma knowledge and awareness and intraocular pressure-related lifestyle habits was statistically significant (r=0.248, p<0.001). Conclusion : Although the level of basic knowledge about glaucoma was high, the level of specific knowledge was low compared to the increase in the incidence of glaucoma over the past 10 years. Key words : Glaucoma, Healthy Life Practices, Intraocular pressure

굴파리과에 기생하는 종으로 알려진 Bitomus (갗고치벌속)는 한국에 4종 보고되어있다. Bitomus는 Fischer (1987, 1994)에 의해 개정되었 고, Papp (1978, 1981)에 의해 한국에서 보고되었다. Bitomus는 움직이지 않게 연결된 마치 껍질과 같은 2-3번째 또는 4번째 복부마디로 다른 속들 과 구별된다. 본 조사연구 결과로 Bitomus indicus를 국내 최초로 보고한다. 기술과 진단형질도판을 수록한다.

Abstract Purpose : To determine the perceptions of soft contact lens wearers regarding contact lens wear and care, and their knowledge of adverse effects of contact lens wear by self-assessment. Methods : An online survey using smartphone was conducted by Naver and Google questionnaires among university students who have experience wearing soft contact lenses. Results : Two hundred twenty-eight soft lens wearers were participated in the study. The average age was 20.9±1.7 years (female 72.8%; male 27.2%) were university students. Approximately 25.4% of respondents did not receive training and practices for safe soft lens wear and 14.1% evaluated themselves as poor at wearing and caring for soft lenses. The most uncomfortable symptom of soft lens wear was dryness at 76.3%, and 36.0% experienced soft lens-related adverse events. The higher type of adverse event was conjunctivitis, and the most common self-reported cause of contact lens-related adverse events was improper lens care and non-compliance to lens wear regimens. Conclusion : Based on the self-assessment of soft lens care that resulted from this survey, we believe that a more proactive approach to intervention by contact lens practitioners is still needed to prevent the risk of adverse events and improve soft lens wearer behavior. Key words : Compliance, Contact lens-related adverse events, Self-assessment, Soft contact lens Authors ORCID:†

본 연구에서는 한국산 미기록속인 이마줄불청객파리속(신칭)과 미기록종인 작은눈이마줄불청객파리(신칭)를 처음으로 보고한다. 우리는 이 종이 포식성 거미의 섭식과정에 관여하는 phoretic relationship의 습성을 갖는 것을 확인하였다. 이 종의 성충에 대한 기재문과 사진 및 DNA바 코드 서열을 제공한다.

This study investigated the effects of exposure frequency, depth of processing, and activity repetition types on vocabulary learning. In total, 78 South Korean fifth-grade students were divided into four conditions. Students in each condition were asked to read a passage with four of the eight target words (exposure: four times) and the other four words (exposure: once) for three days, and to perform the vocabulary activities assigned to each condition. According to the results, exposure frequency and activity repetition type had significant effects on vocabulary learning. Activity repetition type also had a significant interaction effect with exposure frequency and depth of processing. Notably, presenting a word 12 times (4x3) in reading intervals had a more positive impact on vocabulary learning than presenting it three times (1x3), particularly when different vocabulary activities were repeated. Meanwhile, when the same activity was repeated, an activity with a higher depth of processing was more effective for vocabulary learning.

제충국(Tanacetum cineariaiaefolium), 데리스(Derris elliptica), 고삼(Sophora flavescens) 추출물은 다양한 해충을 방제하는데 사용되고 있다. 하지만, 국내에서 판매되고 있는 식물추춞물 자재는 유효성분의 표기가 없고, 살충농도와 살충시간에 대한 자료가 전무한 상황이다. 본 연구에서는 상 용화된 주요 식물추출물의 살충유효성분의 농도를 결정하고 복숭아혹진딧물에 대해 살충농도와 살충시간을 측정하였다. 식물추출물의 살충활성성분 인 pyrethrins, rotenone, matrine과 oxymatrine의 농도는 액체 크로마토그래피에서 표준물질을 활용하여 질량분석을 통해 측정하였다. 식물추출 물을 농도별로 희석하여 복숭아혹진딧물에 살포하여 살충력을 측정하였다. 표준화합물과 비교한 후 질량분석 및 결정했습니다. Myzus persicae에 대 한 lethal concentation과 lethal time을 조사했다. 살포 후 48시간 후 치사 농도(LC50)는 pyrethrins (20.4 ppm), roteone (34.1 ppm), matrine (29.6 ppm)였고, 100 ppm 살포한 LT50은 pyrethrins (13.4시간), rotenone (15.1시간), matrine (14.4시간)로 측정되었다. Kaplan-Meier 생존분 석 결과, 100 ppm에서 세 가지 식물 추출물의 LT50은 대조구인 화학 살충제인 Sulfoxaflor를 살포 처리구보다 유의하게 빨랐습니다. 본 결과는 복숭 아혹진딧물 방제를 위해 식물추출물의 제형화에 단일 또는 혼합 제제를 개발하는데 기준 살충농도와 살충시간을 제고하는데 의미가 있다.

Background: Estrus in cows can be detected through vaginal electrical resistance or conductivity. However, there are no studies measuring vaginal electrical resistance in Hanwoo cows. This study aims to measure the vaginal electrical resistance value in Hanwoo cows and compare it with estrus and ovulation. Methods: Vaginal electrical resistance values of 73 Hanwoo cows were measured before and after estrus at the Gyeongsangbuk-do Livestock Research Institute. Measurements were taken on days -6, -3, -2, -1, 0, 1, 2, 3, and 6 of artificial insemination. Large follicles and ovulation were confirmed using transvaginal ultrasonography. Results: The vaginal electrical resistance averaged 225.6 ± 6.3 Ω days before the artificial insemination date, decreasing until the day of artificial insemination. The average vaginal electrical resistance was 163.7 ± 4.6 Ω on the date of artificial insemination, and 188.8 ± 4.3 Ω one day after artificial insemination, when large follicles were observed. In addition, on the 6th day after artificial insemination, the vaginal electrical resistance averaged 231.4 ± 5.5, which was similar to the 6th day before artificial insemination (222.5 ± 6.3). Transvaginal ultrasonography showed that most of the cows ovulated one day after artificial insemination. Conclusions: The accuracy of estrus is high if the vaginal electrical resistance is measured for cows with confirmed estrus, making is a potentially useful for determining the timing of artificial insemination.

Fungal contaminant in the indoor air is one of risk factors that could damage valuable paper-based records preserved in libraries. In the process of monitoring airborne fungi at the Nara Repository, the National Archives, Seoul, Korea, three fungal strains, DUCC 16098, DUCC 17764, and DUCC17767 were isolated from the archive’s air samples. Fungal identification was performed based on the morphological characteristics and phylogenetic analysis of the internal transcribed spacer (ITS), the 28S LSU rDNA, and β-tubulin gene (BenA), and TEF1-α gene. These DUCC 16098, DUCC 17764 and DUCC17767 strains were identified as Clonostachys farinosa, Penicillium cosmopolitanum, and Cephalotrichum purpureofuscum. These species have not been recorded before in Korea. Information on these fungi will help the monitoring and management of airborne fungi in the archival facilities.

본 연구는 온라인 절화 도매 플랫폼에 대한 이용자 인식, 이용 현황을 알아보고, 본 플랫폼의 발전 방향을 제시하기 위 하여 국내 화훼 장식 종사자 300명을 대상으로 조사 연구하 였다. 연구 결과 화훼 장식 종사자의 99%가 온라인 절화 도매 플랫폼에 대해 인지하고 있었으며, 실제 이용 경험 역시 68% 로 높게 나타났다. 이용자들의 서비스 이용 기간은 1~2년이 46.5%로 가장 많았으며 월평균 구매 횟수는 6~15회가 과반 을 차지하였고, 온라인 절화 도매 플랫폼의 1회 기준 소비 금 액은 15만 원 미만이 62.4%로 나타났으나, 오프라인 절화 도 매시장의 사용 빈도 및 소비 금액이 더 높은 것으로 나타났다 (p<0.001). 화훼 장식 종사자들은 절화의 품질(4.85) 및 상품 의 다양성(4.75)이 절화 구매 시 가장 중요한 고려 요인이었 으며, 온라인 절화 도매 플랫폼에서의 상품 구매 시 과거 구매 경험(3.97)과 상품의 사진(3.87)을 보고 절화 품질을 판단하 는 경우가 가장 많았다. 온라인 절화 도매 플랫폼의 가장 큰 장점으로는 시간을 절약(4.39)할 수 있다는 점으로 인식하고 있었으나, 상품 구매 시 불안 요인으로는 절화 신선도(4.30)와 품질(4.02)에 대한 우려가 높은 것으로 나타났다. 온라인 절화 도매 플랫폼에서 제공하는 서비스 품질에 대해 이용자들은 주 문한 상품과 배송 상품이 일치(4.19)하며, 사용하기 쉬운 페이 지로 구성(4.03)되어 있어 구매 과정(4.00)이 편리하다고 응 답하였으나, 상품 품질에 대한 만족도는 모두 보통 이하로 낮 게 나타났다. 온라인 절화 도매 플랫폼과 오프라인 절화 도매 시장에서의 절화 구매 후 만족도를 비교한 결과 온라인 절화 도매 플랫폼에서는 가격과 반품 처리에 있어 오프라인에 비해 강점을 가지고 있었으나, 가장 중요한 절화 구매 결정 요인인 절화 신선도와 상품 다양성에 있어서 오프라인 절화 도매시장 에 비해 부족함을 보였다. 결론적으로 온라인 절화 도매 플랫 폼의 발전을 위해서는 절화 상품 품질 향상 및 다양성 확보가 필요하며 국내 화훼산업의 지속적인 발전과 성장을 위하여 새 로운 화훼 시장 형태에 대한 다양한 추가 연구가 필요할 것으 로 판단된다.

본 연구는 국내 꽃 정기구독 서비스에 대한 소비자의 인식 과 이용 현황 및 선호도를 파악하기 위해 국내 성인 남녀 중 이용자 225명과 비이용자 291명을 대상으로 설문을 진행하 였다. 대부분의 응답자들은 주로 인터넷과 SNS를 통해 꽃 정 기구독 서비스를 접하였고, 꽃 정기구독 서비스 이용자들은 주로 1~2주에 1회(76.9%), 2~4만 원 가격대(60.4%)의 혼합 된 꽃 상품을 구독하고 있었으며, 대부분 이용 기간은 1년 이 내(84.4%)였다. 꽃 정기구독 서비스를 이용하는 곳은 대부분 집(71.6%)으로, 많은 이용자들이 자기 자신(65.8%)을 위해 서비스를 이용하고 있었다. 꽃 정기구독 서비스에 대하여 이 용자와 비이용자 모두 긍정적으로 인식하고 있었으나, 이용자 들은 비이용자들에 비해 꽃 정기구독 서비스의 가격이 합리적 이고, 삶의 질이 향상되었다고 응답해, 서비스 장점에 대하여 이용자가 비이용자에 비해 더욱 긍정적인 것을 알 수 있었다 (p<0.001). 비이용자들은 꽃 정기구독 서비스 단점으로 포장 쓰레기가 많이 나올 것 같고, 신선도가 떨어질 것으로 우려하 였지만, 이와 반대로 이용자들은 그렇지 않다고 응답하였고, 그 외 단점 문항들에 대해서도 서비스 이용 시 크게 불편함을 느끼지 않는 것으로 나타났다. 응답자들은 꽃 정기구독 서비 스 이용 시 선호하는 상품으로 다양한 꽃이 2~4가지 정도 혼 합된 중간 크기(18~20cm×30~40cm, W×H) 상품을 선호 한다고 응답하였고, 꽃 정기구독 서비스 업체를 선정하기 위 해 고려해야 할 요인으로 이용자와 비이용자 모두 신선도, 꽃 구성, 구매 후기를 중요한 요인으로 응답하였다. 꽃 정기구독 서비스 이용 중 추가로 비용을 지불하면서 이용하고 싶은 서 비스에 대하여 응답자들 모두 절화보존제와 프리미엄 디자인 에 대하여 추가 비용을 지불할 의사가 있다고 응답하였다. 꽃 정기구독 서비스 이용자들은 서비스에 대하여 전반적으로 업 체가 제공하는 정보나 상품에 대해 신뢰하고 있었고, 꽃 정기 구독 서비스 비용은 합리적이라며 긍정적으로 평가하였다. 또 한, 본 서비스에 대한 재이용 의사도 높은 것으로 나타났다. 꽃 정기구독 서비스를 통해 본인을 위한 꽃 소비가 점차 늘어 나고 국내 소비자들의 화훼 소비 형태가 다양하게 변화되었음 을 확인하였으며, 이러한 결과를 바탕으로 앞으로 새로운 국 내 화훼산업 시장이 활성화되고, 지속적인 화훼 소비와 국내 화훼 문화의 발전이 이루어질 것으로 기대한다.

The primary therapeutic approach for Brucella species infections has mainly been based on antibiotic treatment. However, the development of vaccines for brucellosis control remains controversial. Furthermore, there is currently no licensed vaccine available for human brucellosis. This study aims to evaluate the effect of a combination of recombinant protein vaccines against Brucella (B.) abortus infection using a mouse model. Two B. abortus genes, namely dapB and gpm, were cloned and expressed in competent Escherichia (E.) coli DH5α using the pCold-TF vector. Successfully cloned vectors were subjected to PCR amplification using specific primer pairs. The apparent sizes of dapB and gpm were detected at 807 bp and 621 bp, respectively. Besides, the purified recombinant proteins dapB and gpm were detected using SDS-PAGE electrophoresis with correct sizes of 82.86 kDa and 87.61 kDa, respectively. These recombinant proteins were used to immunize mice as a combined subunit vaccine (CSV) to elicit host immunity against B. abortus infection. Mice immunized with CSV exhibited increased proliferation of CD4+ and/or CD8+ T cells at week 7th and 9th before sacrifice, in comparison to the control group. Notably, CSV immunization showed a significant decrease in bacterial burden in the spleen compared to the control group. Altogether, CSV using dapB and gpm induced host adaptive immune response against Brucella infection, suggesting its potential as an effective new subunit vaccine candidate.

Salivary gland dysfunction is a common complication of diabetes. Decreased saliva production and changes in saliva composition may cause oral diseases. Reactive oxygen species (ROS) generation in the salivary glands results in the loss of acinar cells and decreased saliva secretion. Glucagon-like peptide 1 (GLP-1) is the incretin hormone that regulates blood glucose level and can suppress ROS production and inflammation through its antioxidant effects. Dipeptidyl peptidase-4 (DPP-4) is an enzyme that breaks down GLP-1. In this study, we evaluated the pathological role of DPP-4 and GLP-1 on salivary gland dysfunction in type 2 diabetic db/db mice. We observed reduced salivary secretion and histopathological alteration of salivary glands in the db/db mice. The increased DPP-4 and decreased GLP-1 levels in the salivary glands were also detected in the db/db mice. Furthermore, the db/db mice had increased apoptosis and oxidative injury in salivary glands. There was an accumulation of advanced glycation end products and mucus in the salivary glands of the db/db mice. In conclusion, these results showed the possible involvement of DPP-4 and GLP-1, leading to increased ROS-induced apoptosis in diabetes-related salivary gland dysfunction. DPP-4 and GLP-1 may be a pharmacological target for patients with diabetes-related salivary gland dysfunction.