Medicinal plant-derived carbon dots are eco-friendly and possess therapeutic properties. Among the medicinal plants studied throughout the world, Centella asiatica (L.) Urb. is known for its medicinal values, especially its neuroceutical and cogniceutical properties. This work discusses the green synthesis of carbon dots (CDs) using C. asiatica leaves as the carbon source via fast and cost-effective microwave-assisted method, and its physico-chemical characterization via UV–visible, fluorescence and FTIR spectrometry, XRD, SEM, AFM, TEM, SAED, EDX and zeta potential analyses. The study revealed quasi-spherical CDs having size ~ 3–6 nm, polycrystalline nature, and presence of various functional groups like –COOH, –H, =CH2 and C–O–C with UV absorption peaks at 213 and 322 nm. Interestingly, the C. asiatica-derived CDs exhibited blue fluorescence under UV with maximum emission wavelength of 460 nm when excited at 400 nm. Further, these CDs were evaluated for their biological applications, which uncovered their potential in therapeutics such as antimicrobial properties against both Gram-positive and Gram-negative bacteria at a dose of 10 μg, strong antioxidant activity with IC50 values of 165.28 and 128.48 μg mL− 1 in DPPH and H2O2 assays, respectively, and profound anti-inflammatory activity with IC50 value of 106.20 μg mL− 1 in protein denaturation assay. The CDs were also assessed for cytotoxicity using whole blood cells and were found to be safe for in vitro administration. Thus, the C. asiatica-derived CDs can be exploited for their potent biomedicinal properties. Fluorescent carbon dots (CDs) were prepared by microwave-assisted pyrolysis of Centella asiatica leaf extract and purification. The as synthesized CDs were subjected to various physico-chemical characterization and biomedical assays to understand its properties.

Southeast Asia is home to the Straits of Malacca and Singapore, one of the world’s most important sea lines of communication. The closure of the straits to international navigation may adversely affect the well-being of the global economy. On February 11, 2022, the Biden administration announced the new Indo-Pacific strategy, which will continue to deliver on AUKUS. For centuries, the proposed Thai Canal Project has been planned to revolutionize the shipping industry by bypassing the busy waters of the Straits of Malacca and Singapore. If the canal is built under the US Indo-Pacific Strategy, the pre-eminence of the Straits of Malacca and Singapore will not last long. This article analyzes the potential increase of navigation of nuclear-powered submarines through the Straits of Malacca and Singapore and its ensuing environmental implications from a viewpoint of international law. It discusses effects of the proposed canal plan in influencing the shipping industry should this “dream waterway” be constructed.

The development of graphene and graphene-like materials has been a breakthrough in the field of nanotechnology for its exceptional properties. It exhibits extraordinary properties owing to its unique, regular arrangement of carbon atoms in it. However, graphene is usually modified for specific applications, by introducing disorder in the system. Since disorders are ubiquitous during the synthesis of graphene and graphene-like materials, it is best to exploit the defects for tuning its exceptional properties for suitable device applications. Like in any material, the disorder can drastically affect the properties, and hence they are deliberately incorporated into the material. In this review, we discuss topics related to the creation and configuration of disorders in graphene such as corrugations, topological defects, vacancies, adatoms and sp3- defects. The effects of these disorders on the electrical, thermal, chemical and mechanical properties of graphene are analysed subsequently. Finally, we review earlier works on the modulation of structural defects in graphene for specific applications.

The purpose of this paper is to provide a critical overview of the use of social marketing in Asia. A total of 17 countries were included in this paper. We demonstrate the development and trends of social marketing in Asia by highlighting prominent and effective cases. Our findings reveal that social marketing practice represents a wide spectrum of topics. However, public policy and education outweigh adoption of social marketing to address social issues. Several barriers influence adoption and effectiveness of social marketing. We highlight a few and recommend strategies to overcome them.

Introduction: Age-related co-morbidities are common among persons living with chronic Human Immunodeficiency Virus (HIV). However, data are largely absent on the relationship between frailty and incontinence as related to falls—common age-related co-morbidities—among people living with chronic HIV (PLWH). Methods: To inform hospital-based Occupational Therapy (OT) services for PLWH, we performed a case-control study using extracted data from the electronic medical records of PLWH who had received OT at a large academic hospital. Two-hundred-and-four subjects were included in the final dataset; sixty-eight were cases that reported a fall within the last 12 months, while 136 were controls which were PLWH who had not sustained a fall. Results: The association between falls and frailty indicated that persons categorized as ‘pre-frail’ with balance deficits were more likely to fall (OR=2.77 [1.18-6.52]). Women who lacked insurance were less likely to fall (OR=0.38 [0.18-0.82]) and (OR=0.29 [0.09-0.88]) respectively. The association between incontinence and falls among PLWH were not statistically significant in a multivariate adjusted regression model (OR=1.38 [.59-3.22]). Conclusion: Our findings suggest further examination of the person factors of PLWH who are categorized clinically as ‘pre-frail’ or ‘frail’ may improve health outcomes and reduce falls when paired with occupation-based interventions.

At q = 1.81 ± 0.20 × 10-5, KMT-2018-BLG-0029Lb has the lowest planet-host mass ratio q of any microlensing planet to date by more than a factor of two. Hence, it is the first planet that probes below the apparent "pile-up" at q = 5-10 ×10-5. The event was observed by Spitzer, yielding a microlens-parallax πE measurement. Combined with a measurement of the Einstein radius θE from finite-source effects during the caustic crossings, these measurements imply masses of the host Mhost = 1.14+0.10-0.12 M⊙ and planet Mplanet = 7.59+0.75-0.69 M⊕, system distance DL = 3.38+0.22-0.26 kpc and projected separation a⊥ = 4.27+0.21-0.23 AU. The blended light, which is substantially brighter than the microlensed source, is plausibly due to the lens and could be observed at high resolution immediately.

Despite growing research interest in consumer health, well-being and beauty, little is known about factors influencing consumer purchase decisions for female fitness devices. This study focuses on Kegel exercises – exercise routines developed by Dr. Kegel to strengthen pelvic floor muscles – that are recommended by health professionals for patients experiencing health ailments such as urinary incontinence, sexual dysfunction, and dissatisfaction. Despite the benefits, women are not well aware of the role of pelvic floor muscles. The diffusion and acceptance of Kegel exercise and devices among women are likely determined by how comfortable women are about obtaining such benefits. For this reason, feminism should play an important role in shaping women’s desire to engage in Kegel exercises. Thus, this research investigates how feminism is related to Millennial women’s engagement with fitness products, particularly Kegel devices. Drawing on the literatures about sexuality, health, and marketing, we propose that feminism positively influences women’s health-related attitudes (i.e., attitudes towards fitness, fitness opinion leadership, attitude toward core strength, and desire to control sex life), which in turn positively impacts women’s fitness engagement. Fitness engagement, in turn, is expected to predict attitudes towards Kegel exercise and Kegel device purchase intentions. On the other hand, women’s attitudes toward core strength and desire to control sex life are proposed to have a direct, positive impact on attitude towards Kegel exercise. Analysis of PLS-SEM shows general support for the hypotheses. We discuss how interest in Kegel devices could, in turn, lead to positive effects on overall physical and psychological health and provide implications for marketing practitioners.

The Korea Astronomy and Space Science Institute plans to develop a coronagraph in collaboration with National Aeronautics and Space Administration (NASA) and to install it on the International Space Station (ISS). The coronagraph is an externally occulted one-stage coronagraph with a field of view from 3 to 15 solar radii. The observation wavelength is approximately 400~nm, where strong Fraunhofer absorption lines from the photosphere experience thermal broadening and Doppler shift through scattering by coronal electrons. Photometric filter observations around this band enable the estimation of 2D electron temperature and electron velocity distribution in the corona. Together with a high time cadence ($<$12~min) of corona images used to determine the geometric and kinematic parameters of coronal mass ejections, the coronagraph will yield the spatial distribution of electron density by measuring the polarized brightness. For the purpose of technical demonstration, we intend to observe the total solar eclipse in August 2017 with the filter system and to perform a stratospheric balloon experiment in 2019 with the engineering model of the coronagraph. The coronagraph is planned to be installed on the ISS in 2021 for addressing a number of questions (e.g., coronal heating and solar wind acceleration) that are both fundamental and practically important in the physics of the solar corona and of the heliosphere.

One specific manifestation of CSR is the solicitation of donations in collaboration with an NGO. Especially in an online environment, companies can easily control if they present donation options to consumers either before or after the actual purchase moment of their products. The aim of this paper is to investigate how the sequence of purchase and donation requests in the customer journey influences the willingness to donate to a charitable cause and the potential revenues for the seller. As theoretical frame, we use two related concepts of moral self-regulation, namely moral licensing and moral cleansing. We assume that consumers spend a higher sum on a luxury product after donating to an NGO (moral licensing) and vice versa donate a higher sum to charity after purchasing a self-indulgent product (moral cleansing). While we do not consider luxury products as morally questionable per se, prior research has shown that consumers repeatedly feel bad after purchasing a luxury item. Our results indicate that the moral cleansing effect is present in our experiment. On average, participants who first indicate their WTP for a luxury product are subsequently more prone to donating money to an NGO. We could not observe a moral licensing effect at large. Both conditions lead to comparable mean WTP measures, hence to similar total potential revenues. In general, our results indicate that both parties profit the most, if donation options are available after purchase decisions.

Moral licensing is a non-conscious effect that provides a moral boost in the self-concept, which increases the preference for a relative immoral action by dampening the negative self-attributions associated with such behavior. Applied to a marketing context, moral licensing explains why a purchase of a green product (a positive moral act) is likely to increase the likelihood of subsequently purchasing a luxury good (a negative moral act). This study addresses the question how big this effect typically is and which factors influence its size by conducting a Meta-Analysis and a Meta-Regression. Based on a random effects model, the point estimate for the generalized effect size Cohen’s d is 0.365 (SE=0.047; p=0.000). Results of a Meta-Regression indicate, for the first time, that the three moderators cultural background, type of decision and type of comparison explain a substantial amount of the total variation of moral licensing effect’s size.