본 연구는 게임 관련 전문가 23명에게 델파이 기법을 사용해 기존의 게임 가치평가에 추가적 요소들을 추출해 보고자 한다. 기존에 제시된 게임 컨텐츠의 평가 모델을 이용하여 개발 모델의 특성을 전반적으로 검토 한 결과, 컨텐츠를 선정 할 때 가치 평가 요소가 선정되었음을 알 수 있었으며 델파이 분석은 2차에 걸쳐서 이루어졌으며, 1차는 전문가 FGI, 2차는 델파이 설문으로 진행되었다. 결과, 기술 이전 및 보급, 상용화 촉진을 위한 세부 내용 등 관련 항목등에서 보다 세밀한 요소들이 제시되었다. 포커스 그룹 인터뷰를 통해 추가 요인을 추출하고 게임 업계의 컨텐츠 성공에 대한 시장 분석을 통해 시장 규모, 성장 잠재력, 규제 및 시장 매력과 위험을 예측 했으며 이를 통해 관련 업계는 성공 목표에 대한 시장 분석을 통해 시장 규모, 성장 잠재력, 규제, 시장 호소력 및 위험성을 이해할 수 있을 것으로 기대한다. 이 연구는 제안 된 평가 요소가 게임 및 문화 콘텐츠 산업 전 체에 적용될 수 있음을 시사하며 또한 콘텐츠의 시장 가치 평가, 목적 및 목표 설정, 진입 방법 선택, 전략 요소 등 시장 요인을 구성하는 것에 도움이 될 것이다.

몰입감은 게임을 플레이 하는데 중요한 요소이며 궁극적으로 게임 자체의 성공을 좌우하는 재미 그 자체아 결부되기도 한다. 시각적 영역과 밀접한 연관이 있는 해상도는 게임 개발에 있어서 비중있는 요소이며 게임을 개발할 때 염두에 두어야 할 요소이기도 하다. 그래픽 기술의 발전은 하드웨어 발전과 함께해 왔으며, 대부분의 게임은 현재 고해상도의 고품질 그래픽으로 개발되고 있다. 현재 다양한 사용자들의 다양한 해상도 정보 분석 및 시장 조사는 게임 개발자들에게 효과 적인 정보를 제공해 줄 것이며 연구 가치가 있다고 할 수 있다. 본 연구는 지난 4년 간 네이버 소프트웨어 문서분야에서 가장 많은 다운로드 수를 기록하고 있는 문서 뷰어인 'DAVU'의 사용자 정보를 통해 한국인 IT사용자들의 평균 해상도를 분석한다. 'DAVU'는 국내 통합 뷰어 솔루션으로 2014년 국내 문서 및 이미지 뷰어 솔루션을 통해 서비스를 시작했으며 사용자가 뷰어를 실행할 때 개인정보를 제외한 사용자 정보(해상도, 파일 포맷, OS, IE정보 등)를 서버로 전송하여 집계가 가능하다. 이 연구는게임 및 소프트웨어뿐만 아니라 모니터 하드웨어 산업에도 효율적 정보를 제공해 주는 연구가 될 것이다.

Social media has become an integral part of consumers’ daily lives. Individuals connect with one another on social networking sites to like, share, and post information and experiences. As social media become popular among millennials, a growing number of fashion retailers use social media networks in the context of online commerce transactions. Accordingly, an increased number of fashion retailers has been using social media as an advertising tool and a retail channel. Despite the popularity of social media among millennials, empirical findings are limited to reveal factors associated with young consumers’ intentions to use social commerce in fashion shopping. This study sought to examine factors affecting millennials’ intentions to use social commerce in fashion shopping by adopting the technology acceptance model. A total of 524 college students completed an online survey in the U.S. The results of structural equation model confirmed that perceived ease of use, usefulness, and enjoyment had a positive impact on millennials’ attitudes and intentions toward fashion shopping in social commerce. While both perceived ease of use and usefulness positively influenced enjoyment, usefulness had a stronger impact than ease of use. Compared to usefulness, enjoyment had much stronger impact on attitudes. Further structural model analysis revealed a direct, positive influence of perceived usefulness of social commerce on perceived enjoyment of social commerce, which has not been explored in prior studies. These findings provide theoretical and managerial implications.

The objective of this study was to investigate the influence of the addition of caffeine (alkaloid family) to the ejaculates of boar sperm quality as well as investigate their optimum concentrations for increasing the movement of sperms. Semen was collected from 9 boars by the gloved-hand technique one week interval. Semen followed by cryopreservation with egg yolk extender freezing medium using freezing protocol. The collected semen were frozen on the same day. Motility was assessed for % motile cell characteristics using computer-assisted semen analysis (CASA; SAIS SI-100, Medical supply, Korea). Frozen boar sperms were thawed in Beltsville Thawing Solution (BTS) with 5, 10, and 15mM caffeine were then incubated at 38 celsius degree for 20 minutes. In experiment 1, semen were diluted BTS and addition of different concentration of caffeine to the pre-freeze semen cryopreservation. In experiment 2, incubation of frozen-thawed sperm in BTS supplemented with different concentration of caffeine for 20 minutes improved (P<0.05) after semen cryopreservation-thawing on sperm quality. After thawing significantly increased progressive and total motility. The addition of 10 mM caffeine to cryopreserved semen after thawing significantly increased progressive and total motility compared with other treatment. These result suggest that caffeine enhanced post-thaw motility of cryopreserved boar sperm when added after thawing.

The aim of this study was to use an in vitro method and estimate glycaemic index (GI) from porridges to determine the digestibility of porridges. Glycaemic index’s concept is to classify foods on the basis of their postprandial blood glucose response. The GI of a foodstuff is generally measured by determining the increment in blood glucose concentration after the consumption of a test meal over a set period of time and comparing it with an isoglucosidic control meal (normally white bread or glucose) and expressed as a percentage. In this study, the 5 porridges were studied for their starch digestibility. The available starch contents of the samples varied from 65~85 g/100 g dry solids. From in vitro digestion, the porridge samples were Medium glycaemic index foods with calculated GIs ranging from 56 to 67.

The present paper proposes an categorization of commercial fluid products. A total of 21 commercial fluid products were analyzed(porridges, universal design foods, foods for special medical purposes) corresponding to 11 different commercial brands. Joint consideration has been made of viscous behavior (flow and thixotropy) and viscoelastic behavior (oscillatory testing). Rheological measurements were fitted to different rheological mathematical models, and a total of 4 parameters were generated. Our results correspond to three different classes. The three defined classes have been named in a way similar those most commonly used in the literature. Each class has been defined from the parameters allows us to know the common rheological characteristics of any of the products belonging to a given class.

The previous social welfare system medical treatment, economy, society, etc, failed to guarantee “quality of life,” in various respects. In such a situation, green areas can be devised as an alternative means of directly improving the quality of life. Furthermore, natural resources and ecosystem services are essential elements of environmental welfare that have the purpose of supporting health and quality of life. However, despite the importance of such green space, it is often unavailable and there is a great disparity in its distribution among different regions in urbanized areas where residents are intensively dispersed. Therefore, the present study suggests a plan for reducing the regional imbalances in the green environment by using distributive equality and visual access as indexes, and Dalseo-gu, Daegu Metropolitan City as the subject; the research results are deemed to be sufficient for carrying out the important role of providing the basic data necessary for establishing future environmental welfare policy. An examination of the analysis results are as follows. First, Gamsam-dong was revealed to need additional green areas; out of the 167 spaces that were regarded as possible for green biotope construction, 48 spaces appeared possible for additional green biotope construction. However, only 10 spaces were assessed as having the potential for actual green biotope construction, excluding the spaces affected by local green environments. Moreover, given a concern with green equality, a final two were deducted as additional green spaces. The present study is significant in that it accomplishes visual accessibility analysis in terms of visual quality, including the effects of aesthetic enjoyment along with distributive equality from green biotopes; the relevant subfactors include green area supply and demand when constructing additional green biotopes to realize a city with improved environmental welfare. However, the present study is limited in terms of failing to consider the green biotope of local administrative districts affecting the target area of the study because it analyzes equality and disconnected green areas for selecting additional green biotope spaces using Dalseo-gu Daegu as its subject.

The Citrus Leafminer (CLM) larvae creates shallow tunnels in leaves of citrus (orange, mandarins, lemons, grapefruit, etc) and commonly attacks citrus young leaves. They spread almost worldwide (North America, Asia, Australia, etc) and difficult to control by chemicals due to their small size and their behavior of leaf rolling. Due to difficult of managing, our interest is preparing pheromone to control; Z7Z11-16;Al is known as the sex pheromone of this species in Japan. While blending Z7Z11-16;Al and Z7Z11E13-16;Al (3:1 ratio) is known as the pheromone of this insect in North America. Even though commercialized and mass produced already in overseas, there had been almost no report in Korea about synthetic studies and field screening results. The control of the regio-isomers is very important in this kind of pheromone synthesis. Our strategy is the regio-selective Wittig olefination reaction between E-pent-2-enyl(triphenylphsphonium)bromide (phosphonium salt) and the counterpart aldehyde using sodium hexamethyldisilazide (NaHMDS) as a base. All the spectroscopic data (1H, 13C, GC-Mass, etc) are nicely matched with the previously reported values. The field screening in the Jeju island is currently ongoing and will be reported.

Thirty-one Campylobacter jejuni isolates (22 from various local sources, 9 from imported chicken meats) were subtyped with PFGE and flaA typing to investigate their genetic relatedness. Based on a 90% similarity criterion, 23 and 21 genotypic patterns were formed by PFGE and flaA typing, respectively. The discriminatory indices for PFGE, flaA typing, and a composite analysis of PFGE and flaA typing were 0.9785, 0.9527, and 0.9871, respectively. Similar patterns in composite analysis were observed between sources (cattle and chicken, and cattle and human), indicating that reservoir animals may have been the source of human campylobacteriosis. Therefore, strict hygiene measures from farm to table should be implemented to prevent diseases due to C. jejuni in humans.

최근 인구 증가 및 기후 변화로 인해 채소를 비롯한 농작물에 대한 수요가 증가되고 있는 가운데 우즈베키스탄에서는 채소 및 식량자원의 자급 달성을 위한 대규모 사업을 추진하여 왔다. 그 결과독립 후 현재까지 약 20년간 채소 생산량은 약 140%, 감자는 168%각각 증가하였고, 특히 최근 5년간에 채소 생산량은 1.7배나 증가하였다. 채소 생산량의 증가에도 불구하고 우즈벡은 여전히 수요량을 충족하지 못하고 있는 실정이다. 이는 인구 증가와 더불어 정부의 목화와 곡물 생산 집중, 관개면적의 확대 제한 등에 기인하고있다. 우즈벡의 채소산업의 미래는 생산 장려와 수출가능성 때문에 밝다고 할 수 있다. 특히 채소 공급업자들은 러시아, 카자흐스탄과 같은 주요 수출시장에 기반을 구축해 있고 그 외 중앙아시아와 중국 시장도 우즈벡 채소산업의 성장 가능성을 말해 주고 있다.

In order to isolate thermophilic compost-promoting bacteria with high activity of cellulase and xylanase, spent mushroom substrates with sawdust were collected from mushroom cultivation farm, Jinju, Gyeongnam in Korea. Among of the isolates, one strain, designated HJ01 was selected by agar diffusion method. The strain HJ01 was identified as members of the Bacillus subtilis by biochemical characteristics using Bacillus ID kit and VITEK 2 system. Comparative 16S rDNA gene sequence analysis showed that strain HJ01 formed a distinct phylogenetic tree within the genus Bacillus and was most closely related to Bacillus subtilis with 16S rDNA gene sequence similarity of 99.3%. On the basis of its physiological properties, biochemical characteristics and phylogenetic distinctiveness, strain HJ01 was classified within the genus Bacillus, for which the name Bacillus subtilis HJ0 is proposed. The cellulase and xylanase activity of B. subtilis HJ0 was slightly increased according to bacterial population from exponential phase to stationary phase in growth curve for B. subtilis HJ01.

1,1- Bis(3’-indolyl)-l-(p-methoxyphenyl)methane (DIM- C- pPhOCH.3) is a methylenc - substituted diindolylmethanes (C-DIM) ana log that acti vates the orphan receptOl‘ nerve growth factor-induced-B (NGFI-B, Nur77) , RNA inteference studies with small inhibitory RNA for Nur77 demonstrate that DIM-C-pPhOCH:J induces Nur77-dependent and - independent apoptosis, and this study has focused on delineating the Nur77-independent proapoptotic pathways induced by the C-DIM analog DIM-C-pPhOCH3 induced caspase-dependent apoptosis in RKO colon cancer cells through decreased mitochondrial membrane potential which is accompanied by increased mitochondrial bax/bcl-2 ratios and release of cytochrome c into the cytosol DlM-C一pPhOCH.3 also induced phosphatidylinositol-3-kinase-dependent activation of early growth response gene-l whi ch, in turn, induced expression of the proapoptotic nonsteroidal anti-inflammatory drug- activated gene-l (NAG- l) in colon tumors in athyrnic nude mice bearing RKO cells as xenografts, DIM-C-pPhOCH.3 also activated the extrinsic apoptosis pathway through increased phosphorylation of c- jun N-terminal kinase which, in turn, activated C/EBP homologous transcription factor (CHOP) and death receptor 5 (DR5) , Thus, the effectiveness of DIM-C-pPhOCH.3 as a tumor growth inhibitor is through activation of Nur77-dependent and -independent pathways

Human saliva contains a large number of proteins and peptides whose composition may alter as a consequence 。f disease. To date. however‘ the proteins and peptides that routinely populate thi s ora l fluid a re largely unknown To provide a catalogue of saliva proteins, we have surveyed the unstimulated human whole saliva by us ing shotgun proteornics. For the shotgun approach, whole saliva proteins were digested into peptides with ChemDigestD ‘ and the resul ting peptide fragments were separated by RP-HPLC, followed by each fraction was t ryptic digestion. ChemDigestD-Trypsin digested peptides were analyzed by tandem mass spectrometry(MS/MS) us ing a nano-LC eq 버 pped quadrupole-time of f1ight mass spectrometer, and the obtained spectra were searched against human protein seq uence data base using MASCOT. Shotgun proteomics allowed a total of 291 human pr。 teins to be confidently assigned . The largest group(17 .2%) of the identified proteins sorted into functional catego ries was included in t he signal t ransduction funct ion except for the hypothetical 0 1' unknown function. This work provides a valuable s ta rting point for the analysis of human salivary proteins and their biological functions and candidates from human whole sali va that may prove to be of diagnostic and therapeutic significance

The human ELAV(embryonic lethal abnormal vision)-like protein HuR stabilizes a certain group of cellular mRNAs that contain AU- ri ch elements in theil‘ 3’• untranslated region, Dysregulation of mRNA s tability may be relevant in tumor biology and may lead to abnormal expression of several proteins in malignant tumors, The aim of this study is to identify the differentially expressed proteins according to the functi onal activi ty of HuR Methods : We used stabl e expression of small interfering RNA(siRNA) of HuR gene to inhibit the expression of HuR in human ora l car cinoma cell lines‘ KB cell line and YD10B cell line‘ and compared the proteomic changes between s iRNA-treated and cont rol cell line using two-dimensional gel electrophoresis , Flow cytometry caliber scan(FACS) was employed to investigate the effects of HuR on cell apoptosis and proliferation , Results: Seventeen differentially expressed proteins between the two cell lines were identified by electrospray ioruzati on quadrupole time-of- fl ight mass spectrometry(ESI-Q-TOF MS) and database searching, Among them there are eleven proteins which are significant ly up- regulated in siRNA- treated cell line, which include heat shock protein 10(influencing nucl eocytoplas rnic transpo 다， cell dedifferentiation , and inhibition of apoptosis) , keratin 19(basal cell differ ent iat ion) ‘ and nucleoside diphosphate kinase B(G protein activator), etc Enolase 1 and Ml of pyruvate kinase a re the representatives of signifi cantly down-regulated proteins in siRNA-treated cell 11l1e Conclusion : Our data suggest that HuR participate in mRNAs stability of proteins that have the counter effects in the carcinogenesis of oral ca ncer , And the functiona l proteomics a re needed to elucidate the detailed interactions between HuR and t hese molec ules

SPG (Shirasu porous glass) 관형 막이 설치된 회분식 막유화 장치를 사용하여 이온성 약물이 담지된 단분산 polycaprolactone (PCL) 마이크로캡슐을 제조하기 위한 막유화 공정변수의 최적조건을 결정하였다. 마이크로캡슐에 담지된 이온성 약물로는 양이온성인 lidocaine-hydrochloride, 중성인 sodium salicylate와 음이온성인 4-acetaminophen의 3가지를 사용하였으며, PCL 마이크로캡슐로부터 이들 모델약물의 방출거동을 검토하였다. 캡슐제조에 사용된 PCL의 농도와 분자량, 막간 압력차, 분산상과 연속상에 첨가시킨 유화제의 농도, 연속상의 교반속도가 막유화법으로 제조된 PCL 캡슐의 크기와 크기분포에 미치는 영향을 검토하였다. 이들 공정변수의 조절을 통해 평균 크기 약 5 μm의 균일한 마이크로캡슐을 제조할 수 있었다. 약물 방출실험 결과 산성조건에서 알칼리조건으로 방출환경이 변화됨에 따라 약물 방출속도가 증가하였다.

The purpose of this paper is to examine how the social system of deposit insurance affected the financial market in Korea. Specifically, we want to know how much the risk-seeking behavior of financial institutions has increased or decreased. The most important feature of the deposit insurance system is to prevent the insolvency of financial institutions and to properly protect depositors. In recent studies, it has been argued that characteristics of deposit insurance bring moral hazard of financial institutions and that financial institutions make unreasonably risky investments. Therefore, in this study, we will first examine whether such previous research can be applied to the Korean financial market. Next, we will examine the appropriateness of the differential premium rate that is currently used for each financial institution in the Korean financial market. In order to test the first hypothesis, we used the Capital Asset Pricing Model (CAPM) to calculate the total risk for each financial institution. As a result, significant changes were found in all regions before and after the introduction of the deposit insurance system. As for testing the second hypothesis, we conducted a variance analysis of financial institutions' indexes before and after the introduction of the deposit insurance and we discovered significance of the total risk difference.