A 13-year-old female lion underwent a simple mastectomy for a rapidly growing abdominal mass, confirmed as mammary adenocarcinoma after histopathological examination. Mammary tumors are common in domestic cats but less frequently reported in African lions. This report presents the first documented case of mammary adenocarcinoma in an African lion in South Korea. The mass was successfully excised through stable anesthesia and surgery. This report adds to the limited literature on mammary tumors in large felids and discusses the need for tailored management strategies.
온실 내부 환경은 지역에 따라 외부 환경의 영향을 지속적으로 받는다. 본 연구는 몽골, UAE(아부다비), 호 주(퀸슬란드) 등 지역별로 구축된 한국형 스마트 온실의 환경 특성을 비교하고자 수행하였다. 몽골과 아부다비의 온실 모두 내외부 엔탈피 차이가 감소함에 따라 환기율이 증가하였다. 아부다비의 반밀폐형 온실에서는 10시부터 14시까지 평균 내부 기온이 외부 기온보다 약 7-10°C 낮았고 내부 VPD(12mbar)는 외부 VPD(56mbar)보다 4.6 배 낮았는데 이 결과는 포그 시스템 운영과 관련이 있는 것으로 보인다. 퀸즐랜드 온실의 경우, 내부 온도가 외부 온 도보다 11시 기준 약 3.81°C 높았고, 내부 엔탈피와 VPD가 외부 온도보다 높았으며, 내부와 외부의 엔탈피 차이가 증가함에 따라 환기율이 증가하였다. 이 결과로 엔탈피를 낮추는 것은 환기와, VPD를 낮추는 것은 포그 시스템 작 동과 관련이 있는 것을 알 수 있다. 또한, 작물 생육에 적합한 환경 조건을 효과적으로 관리하기 위해 엔탈피와 VPD 기반의 포그, 환기 또는 난방 시스템이 필요하다는 것을 알 수 있다.
Industries that use or produce radionuclides have unintentionally released these substances into surrounding soils and sediments. To address this problem, Beautiful Environmental Construction (BEC) Co. developed the BEC’s Radioactive Soil Decontamination (BERAD) system to remove contaminants and reduce the volume of radionuclide-contaminated soils. Owing to the limited availability of radioactive isotopes such as 60Co, 90Sr, 137Cs, and uranium-contaminated soil, naturally occurring elements in soil were used in this demonstration. The soil was divided into six size fractions via manual wet sieving and the BERAD system. Then, the concentrations of uranium, cobalt, strontium, cesium, and iron in each fraction were measured. The results of both separations showed that a considerable amount of each element is retained in the finer size fractions (<0.2 mm). After BERAD separation, the corresponding values yielded 53% uranium, 45% strontium, 66% cobalt, and 53% cesium in the fine size (<0.2 mm) fractions of 35% by weight. The study found that the concentrations of these elements increased as the particle sizes decreased. Iron and micaceous minerals played a significant role in retaining the elements. The pilot scale BERAD system yielded results that were similar to those obtained via laboratory wet-sieving and was successfully demonstrated as a soil washing technology.
Ectopic ureter refers to a congenital anomaly in which one or both ureters do not connect to the urinary bladder at the correct anatomical site. This case report discusses the case of a 6-year-old female mixed-breed dog diagnosed with chronic urinary incontinence, systemic hypertension, pancreatitis, and sepsis resulting from an ectopic ureter. Treatment involved an initial nephro-ureterectomy to address severe pyonephrosis, followed by ureteroneocystostomy for the remaining functional kidney. Post-surgical outcomes showed notable improvements in clinical symptoms, laboratory findings, and blood pressure. This report emphasizes the need for early diagnosis and appropriate surgical treatment in cases of ectopic ureter. Additionally, it aims to present the clinical symptoms and conditions resulting from prolonged disease progression, as well as the corresponding treatment methods and prognosis.
One of the key challenges for the commercialization of carbon nanotube fibers (CNTFs) is their large-scale economic production. Among CNTF spinning methods, surfactant-based wet spinning is one of the promising techniques for mass producing CNTFs. Here, we investigated how the coagulation bath composition affects the spinnability and the properties of CNTFs in surfactant-based wet spinning. We used acetone, DMAc, ethanol, and IPA as coagulants and analyzed the relationship between coagulation bath composition and the properties of CNTFs in terms of kinetic and thermodynamic coagulation parameters. From a kinetic perspective, we found that a low mass transfer rate difference (MTRD) is favorable for wet spinning. Based on this finding, we mixed the coagulant bath with solvent in a proper ratio to reduce the MTRD, which generally improved the wet spinning. We also showed that the coagulation strength, a thermodynamic parameter, should be considered. We believe that our research can contribute to establishment of surfactant-based wet spinning of CNTFs.
Severe Fever with Thrombocytopenia Syndrome (SFTS) is a newly emerging tick-borne disease caused by the SFTS virus (SFTSV), which belongs to the phlebovirus in the Bunyaviridae family. SFTSV is enveloped with a tripartite ambisense RNA genome. The L segment encodes the viral RNA-dependent RNA polymerase, the M segment encodes the two glycoproteins, Gc and Gn, and the S segment encodes the nucleoprotein (NP) and the nonstructural protein (NSs). NP participates in ribonucleoprotein (RNP) packaging and commonly detected early after infection, suggesting that the N protein is possible to be used as a target antigen for early diagnosis of SFTSV infection. In this study, we analyzed a highly immunogenic multi-epitope using GnGc and NP genes from a consensus sequence of SFTSV strain isolated from infected patients in Korea. The selected genes are constructed to the expression vector plasmid pJHL65 and the recombinant plasmid vector was transformed into the Δasd Δlon ΔcpxR Salmonella Typhimurium attenuated strain JOL912 and the expression of these antigens was verified by immunoblotting assay. We observed the significant levels of systemic IgG and mucosal IgM responses against the JOL912-derived antigen in the immunized BALB/c mice. The level of CD3+CD4+, CD3+CD8+ T lymphocyte subpopulation and TNF-α were also highly regulated in splenic T cells re-stimulated in vitro with NP and Gn/Gc multi-epitope selected antigens. Therefore, immunized mice with NP and Gn/GC multi-epitope recombinant proteins of attenuated Salmonella delivery system elicited T cell-related immune response, inducing an effective immune response. In conclusion, the attenuated Salmonella expressing NP-GnGc multi-epitopes could be a novel vaccine candidate against the SFTS virus.
수염풍뎅이(Polyphylla laticollis manchurica)는 과거에는 흔히 발견되었으나, 1970년대 이후 한반도 내 개체수 가 급격히 감소하여 2005년 환경부에 의해 멸종위기 야생생물 Ⅰ급으로 지정되었다. 또한 해당종의 분자생물학적 연구는 멸종위기종이라는 특성으로 인해 제한적으로 진행되었다. 그로 인해 NCBI 등 공공 데이터베이스에서 제공되는 서열정보들 또한 부족한 실정이다. 이 연구는 이러한 한계를 극복하고 수염풍뎅이의 유전적 특성을 규명하기 위해 생물정보학적 기술을 활용하여 전사체 분석을 진행하였다. Illumina HiSeq 2500 플랫폼을 사용하여 53,433,048개의 RNA reads를 얻었으며, Trinity와 TGICL을 이용한 De novo 어셈블리 분석을 통해 18,172개의 unigenes를 생성하였다. 생성된 unigenes는 GO, KOG, KEGG, PANM DB를 활용하여 annotation을 진행하였다. 그 결과, GO 분석에서는 ‘binding and catalytic activities’와 관련된 항목이 높은 발현을 보였으며, KOG 분석의 경우 ‘Cellular Processes and Signals’ 범주가 높은 비율을 나타내었다. KEGG 분석을 통해 2,118개의 unigenes가 metabolic 카테고리에 annotation된 것을 확인하였다. SSR 모티프 분석에서는 AT/AT (42.90%) 모티프, AAT/ATT (13.13%) 모티프 순으로 많이 나타나는 것을 확인하였다. 이 연구를 통해 분석한 결과 들을 이용하여 유전자원 및 종 정보를 실시간 제공 및 정보 공유가 가능하도록 Database 및 web-interface를 구축하 였으며, 이러한 자료들은 국내 멸종위기종인 수염풍뎅이의 고유한 유전적 특성을 발굴 및 확보할 수 있는 기반자 료로써 활용될 수 있을 것으로 사료된다.