본 연구에서는 α-glucosidase 저해활성이 우수한 천연 자원을 개발하기 위하여 개똥쑥으로부터 천연 물질을 분리·동정하고 분리된 물질에 대하여 α-glucosidase 저해활성을 측정하였다. 개똥쑥 잎과 줄 기의 chloroform층과 ethyl acetate층으로부터 각각 6개와 5개의 화합물을 분리하였다. 분리한 화합물 중 chloroform층으로부터 분리된 ArteCA(M.W. 316g/mol, C16H12O7)는 isorhamnetin, ArteCB(M.W. 360g/mol, C18H16O8)는 chrysosplenol D, ArteCC(M.W. 316 g/mol, C16H12O7)는 rhamnetin, ArteCD (M.W. 374g/mol, C18H16O8)는 chrysosplenetin, ArteCE(M.W. 284g/mol, C21H20O12)는 acacetin 그리 고 ArteCF(M.W. 270g/mol, C16H14O4)는 imperatorin으로 확인되었다. 한편 EtOAc층으로부터 분리된 ArteEAA(M.W. 178g/mol, C9H6O4)는 6,7-dihydroxy coumarin, ArteEAB (M.W. 192g/mol, C10H8O4) 는 scopoletin, ArteEAC (M.W. 448g/mol, C21H20O11)는 kaempferol-3-O-b-D-glucoside, ArteEAD (M.W. 464 g/mol, C21H20O12)는 quercetin-3-O-b-D-glucoside 및 ArteEAE(M.W. 318g/mol, C15H10O8)는 myricetin으로 확인되었다. 이 중에서 ArteEAE(myricetin)는 α-glucosidase에 대하여 97.3%의 높은 저해활성을 가지고 있었으므로, 혈당조절용 건강식품 또는 치료제 개발을 위한 물질로 활용될 수 있을 것으로 판단되었다.
Seung Kyu Ahn, Young-Min Goo, Min Ji Kim, Hyo-Hyung Lee, Keon Hee Ko, Kyeong Yeol Oh, Mi-Young Yoon, Ji-Yun Min, Gyeong-Seon Kim, Yun Geun Kim, Dong Hwan Kim, Jun Young Kim
Ji Yun Min, Jun Young Kim, Young Min Goo, Seung Kyu Ahn, Hyo Hyung Lee, Keon Hee Ko, Min Ji Kim, Yun Geun Kim, Mi Young Yoon, Gyeong Seon Kim, Kyeong Yeol Oh, Myung Suk Choi, Dong Hwan Kim
Hae Chune Choi, Yeon Gyu Kim, Sang Nag Ahn, Ha Cheol Hong, Huhn Pal Moon, Soo Yeon Cho, Hung Goo Hwang, Chang In Yang, Moon Tae Song, Sae June Yang, Hong Yeol Kim, Rae Kyeong Park, Yun Sun Kim
“Surabyeo” is a new japonica rice cultivar developed from a backcrossed combination between the F1 of “Suweon 345/ Kanto PL4” and “Suweon 345” of lodging tolerant, semi-dwarf, high-quality rice line by the rice breeding team of National Crop Experiment St
Hae Chune Choi, Yeon Gyu Kim, Ha Cheol Hong, Huhn Pal Moon, Sang Nag Ahn, Hung Goo Hwang, Moon Tae Song, Sae June Yang, Hong Yeol Kim, Seong Sook Han, Soo Yeon Cho, Rae Kyeong Park, Moo Nam Chu
“Saechucheongbyeo” is a new japonica multiline for blast resistance, which was composed of equal proportions in seed weight of three near-isogenic lines of two combinations. The recurrent parent, “Chucheongbyeo”, was a high-quality rice cultivar with susc
Yeon Gyu Kim, Hae Chune Choi, Ha Cheol Hong, Huhn Pal Moon, Hung Goo Hwang, Sang Nag Ahn, Yeong Seop Shin, Sae June Yang, Hong Yeol Kim, Seong Sook Han, Soo Yeon Cho, Rae Kyeong Park, Moo Nam C
Anseongbyeo is a japonicaseed weight of three near-isogenic lines of blast resistance. The recurrent parent, Suweon345, was a high-quality and semi-dwarf rice cultivar with susceptability to neck blast. The blast-resistance donors for each liens were SR12