지속적인 기후변화로 인해 매개 곤충을 통한 다양한 신종감염병이 국제적으로 확산되고 있으며, 발생빈도 또한 증가하는 추세이다. 이러한 매개질병을 관리하기 위해서는 질병을 매개하는 매개체에 대한 정보와 지속적 인 모니터링이 필요하다. 이 연구는 제3급 법정 감염병으로 지정된 중증열성혈소판감소증후근(Severe Fever with Thrombocytopenia Syndrome, SFTS) 및 라임병(Lyme disease) 등의 매개체로 알려져 있는 참진드기를 대상으로 충남 당진 일대에서 2018년부터 2023년까지 총 6년, 4월-11월의 기간동안 월 1회 4개의 환경(무덤, 산길, 잡목림, 초지)에서 드라이아이스 유인트랩을 사용하여 발생밀도를 조사하였다. 그 결과 2018년 16,996마리, 2019년 16,698마리, 2020년 6,417마리, 2021년 7,380마리, 2022년 3,451마리, 2023년 3,465마리로, 총 54,407마리가 채집되 었으며, 초지에서 가장 많이 채집되었다. 채집된 참진드기는 2속 3종으로 작은소피참진드기(Haemaphysalis longicornis), 개피참진드기(H. flava), 일본참진드기(Ixodes nipponensis)이며, 작은소피참진드기 (H. longicornis) 가 42,489마리(78.09%)로 높은 우점도를 보였으며, SFTS 보유 여부를 확인하기 위해 RNA 추출 및 Nested RT-PCR 단계를 걸쳐 전기영동을 수행하였으나 양성 검체는 0건으로 확인되었다. 이러한 연구 결과는 SFTS의 주요 매개 체인 참진드기 발생 양상 파악 및 매개 질병 관리 전략 수립에 기초 자료로서 활용될 수 있을 것으로 사료된다.

국립기상연구소의 보고에 의하면 최근 한반도의 기온 상승으로 인해 온대내륙성 기후형에 속했던 지점은 온대해양성 기후형으로, 온대해양성 기후형은 아열대습윤 기후형으로 변화하고 있다. 이러한 한반도의 기후 변화는 환경 변인에 민감한 질병 매개 곤충의 분포와 밀도 변화에 영향을 미칠 수 있어 지속적인 모니터링이 중요하다. 이 연구는 철새도래지 내 발생 및 유입될 수 있는 모기와 관련 바이러스 감염률을 확인하기 위해 충남 당진의 철새도래지에서 BG-sentinel trap 및 LED trap을 사용하여 2021년부터 2023년까지 4-11월간 월 2회 수행하 였다. 채집된 모기는 총 3,723마리로, 4속 16종을 확인하였다. 그 중 금빛숲모기 (Aedes (Aedimorphus) vexans nipponii) 가 1,711마리(45.96%)로 가장 높은 우점도를 나타냈으며, 흰줄숲모기 (A. (Stegomyia) albopictus) 와 큰검 정들모기 (Armigeres (Armigeres) subalbatus) 각각 588마리(15.79%), 빨간집모기 (Culex (Culex) pipiens pallens) 269마리(7.23%)로 나타났다. 채집된 모기의 Flavi-virus 감염 여부를 확인하기 위해 RNA 추출 및 RT-PCR을 통해 확인하였으나, 모두 음성으로 확인되었다. 이러한 연구 결과들은 기후변화에 맞추어 변화하는 감염병 매개 모기 의 발생 현황을 감시·예측하는데 유의한 자료로 활용될 수 있으며, 향후 모기 매개 질환 발생을 예측하기 위한 기초 자료로 활용될 수 있을 것으로 사료된다.

The purpose of this study is to develop up-cycling fashion design methods centered on discarded denim material for the study of original up-cycling design methods. Up-cycling fashion design work was developed using digital clothing technology. This is a recent hot topic among sustainable fashion design methods. Up-cycling fashion design expression methods (categorized as dismantlement, collages, dépaysement, grafting, weaving, and tearing) were centered on design methods. These methods create various three-dimensional modeling effects in planar forms, whereby five pieces can be applied to the fabric and digitally produced. The results are as follows: First, the use of discarded denim fabric for the development of up-cycling fashion design pieces enabled the recycling of existing resources, provided solutions to environmental pollution problems, and provided expansion opportunities for design processes for sustainable fashion products that expand the design value of denim products and their utility. Second, new eco-friendly fashion designs that attempt to achieve diversity in modern fashion trends could be presented through formative contemporary fashion produced by up-cycling work products. Third, up-cycling fashion design work is expected to provide opportunities for eco-friendly fashion design methods. This will expand the value of sustainable fashion design by recycling simple waste materials through the use of three-dimensional digital clothing technology and further through the presentation of expanded life cycles that extend product planning, production, and life cycles.

This study aims to develop a hanbok design method in response to recent changes in consumption trends that emphasize new aesthetic and cultural values, which contrast with the existing cultural order and repetitive normative styles in fashion designing. With this in mind, our study explores the main features of deconstruction fashion design as a theoretical guide for developing a methodology for deconstruction hanbok design, on the basis of which new, experimental and creative hanbok design works can be produced. To do this, we first investigate current trends in hanbok design and changing concepts of Korean fashion design through literature review of previous studies. Secondly, we explore deconstructionism and analyze its features to lay down the foundation for a post-modern approach in hanbok design. As the result of analysis, the main features of deconstruction fashion design are summarized as the following: 1) non-finishing, 2) decomposing and recomposing, 3) recycling, 4) transparent, 5) grunge, 6) flattening, and 7) exaggeration. Based on the identified core features of deconstruction fashion design, we develop a creative method of hanbok design in the context of modern Korean fashion design. Finally, we show five design outputs via a 3D digital fashion design process using the CLO3D software program.

This study aims to examine the effects of taping of the ankle joint on the static and dynamic balance and gait ability of stroke patients. Twenty-six stroke patients receiving physical therapy at a hospital located in Gyeonggi-do were divided equally into a group that had taping in physical therapy and an ordinary physical therapy group. They exercised for 30 minutes each, 3 times per week for 8 weeks from June to August 2011. Romberg’s eye open and eye closed tests, limits of stability(LOS), forward and back test, timed up and go test(TUG) and 10-meter gait velocity test were performed to evaluate static balance, dynamic balance, and gait ability, respectively, prior to and 8 weeks after the intervention. Differences within each group in relation to the lapse of time were compared by a paired t-test. Differences between the two groups were compared by an independent t-test. Regarding comparison of differences within each group, all tests resulted in significant changes in both groups after the intervention (p<.05). Comparison of differences between the two groups showed that taping in the physical therapy group had significantly better test results than the ordinary physical therapy group in all measured items(p<.05). The after effects of ankle taping on stroke patients are more efficient and effective than ordinary physical therapy alone in improving balance and gait ability.

Oct4 and Nanog are well-known transcription factors related with self renewal of embryonic stem cell. In low-dose of Nanog, transcription of oct4 is increased; however, oct4 is down-regulated upon high-dose of Nanog. There is a negative feedback loop between oct4 and Nanog. To identify this regulation, we generated 4 nested sets for mouse oct4 promoter. Luciferase activities of oct4 were declined upon high-dose Nanog in all constructs. The declined effects of oct4 upon high-dose Nanog were moderated with DNMT and HDAC inhibitors (5-AZA-cytidine and trichostatin A) in 3 constructs (1867, 1346, 754). But, one construct (2179) was only sensitive to TSA. Taken together, these effects were also represented in semi-quantitative RT-PCR and Western blotting data. These data suggest that negative regulation of oct4 gene upon high-dose Nanog would be accomplished by DNMT and HDAC. Further, it will be studied whether these constraining molecules bind to CR1-4 region of oct4 promoter upon low- and high-dose of Nanog.

In solstices during the solar minimum, the hemispheric difference of the equatorial ionization anomaly (EIA) intensity (hereafter hemispheric asymmetry) is understood as being opposite in the morning and afternoon. This phenomenon is explained by the temporal variation of the combined effects of the fountain process and interhemispheric wind. However, the mechanism applied to the observations during the solar minimum has not yet been validated with observations made during other periods of the solar cycle. We investigate the variability of the hemispheric asymmetry with local time (LT), altitude, season, and solar cycle using the electron density taken by the CHAllenging Minisatellite Payload satellite and the global total electron content (TEC) maps acquired during 2001–2008. The electron density profiles provided by the Constellation Observing System for Meteorology, Ionosphere, and Climate satellites during 2007–2008 are also used to investigate the variation of the hemispheric asymmetry with altitude during the solar minimum. During the solar minimum, the location of a stronger EIA moves from the winter hemisphere to the summer hemisphere around 1200–1400 LT. The reversal of the hemispheric asymmetry is more clearly visible in the F-peak density than in TEC or in topside plasma density. During the solar maximum, the EIA in the winter hemisphere is stronger than that in the summer hemisphere in both the morning and afternoon. When the location of a stronger EIA in the afternoon is viewed as a function of the year, the transition from the winter hemisphere to the summer hemisphere occurs near 2004 (yearly average F10.7 index = 106). We discuss the mechanisms that cause the variation of the hemispheric asymmetry with LT and solar cycle.