We investigated the effect of moderate- and high-intensity resistance training on hippocampal neurotrophic factors and peripheral CCL11 levels in high-fat diet (HFD)-induced obese mice. C57/black male mice received a 4 weeks diet of normal (control, CON; n = 9) or a high-fat diet (HF; n = 27) to induce obesity. Thereafter, the HF group was subdivided equally into the HF, HF + moderate-intensity exercise (HFME), and HF + high-intensity exercise (HFHE) groups (n = 9, respectively), and mice were subjected to ladder-climbing exercise for 8 weeks. The hippocampal brain-derived neurotrophic factor (BDNF) and nerve growth factor (NGF) levels were significantly lower in the HF group than in the CON group (p < 0.05). In addition, in the HFME and HFHE groups were significantly higher than in the HF group (p < 0.05). The peripheral CCL11 levels were significantly higher in the HF group than in the CON group (p < 0.05). In addition, in the HFME and HFHE groups were significantly lower than in the HF group (p < 0.05). However, there was no significant difference according to the exercise intensity among the groups. Collectively, these results suggest that obesity can induce down-regulation of neurotrophic factors and inhibition of neurogenesis. In contrast, regardless of exercise intensity, resistance training may have a positive effect on improving brain function by inducing increased expression of neurotrophic factors.

The purpose of this study was to investigate the effects of different types of exercise training on neurodegeneration and cognitive function in mice with impaired glucose tolerance (IGT). Thirty-six male C57BL/6 mice were randomly assigned to the control (CO, n = 9) and impaired glucose tolerance (IGT, n = 27) groups. The IGT group consumed 45% high fat diet for 4 weeks and received 40 mg/kg of streptozotocin twice in the lower abdomen to induce IGT. After the IGT induction period, the IGT group was subdivided into IGT + sedentary (IGT, n = 9), IGT + endurance exercise (IGTE, n = 9), and IGT + resistance exercise (IGTR, n = 9). The IGTE and IGTR groups performed treadmill and ladder climbing exercises 5 times per week for 8 weeks, respectively. Fasting glucose and glycated hemoglobin (HbA1c) levels were significantly higher in IGT group than in CO, IGTE, and IGTR groups (p < 0.05). HOMA-IR was significantly higher in IGT group than CO group (p < 0.05). Hippocampal catalase (CAT) was significantly lower in IGT group than in CO group (p < 0.05), while beta-amyloid (Aβ) was significantly higher in IGT group than in CO group (p < 0.05). Hippocampal tau was significantly higher in IGT group than in CO, IGTE, and IGTR groups (p < 0.05). The Y-maze test performance for cognitive function was significantly lower in IGT group than in CO, IGTE, and IGTR groups (p <0.05). These results suggest that IGT induces neurodegeneration and negatively affects cognitive function, while regular exercise may be effective in alleviating neurodegeneration and cognitive decline regardless of exercise type.

The present study identified several antecedents that create perceived resistance to supply chain management (SCM) change. This work particularly emphasizes SCM change, which is notable given its central role in reacting market orientation and varied environmental and managerial conditions. A careful case study on a small and medium sized food production company in South Korea leads to the formulation of our framework including one second-order construct of ‘resistance’ as well as eight first-order constructs of ‘implementing the payment terms’, ‘balancing of business process’, ‘fear of responsibility’, ‘business sustainability transparency’, ‘past experience of failure’, ‘competence of work personnel’, ‘cooperation with third parties’ and ‘sharing personnel information with partner’. The hypothesized relation of first- and second-order construct was validated using survey sample data collected from 350 respondents who completed their questionnaire instrument. Results from confirmatory factor analysis revealed that nomological validity was established at statistical significance level by identifying six first order constructs of ‘implementing the payment terms’, ‘fear of responsibility’, ‘business sustainability transparency’, ‘past experience of failure’, a conbined construct of 'competence of work personnel/ cooperation with third parties’ and ‘sharing personnel information with partner’. The findings from our work are expected to provide important insights to the strategy for SCM risk management for small and medium sized company.

In this study, the out-of-plane seismic resistance of lightly-reinforced existing walls strengthened with thick RC jacket was investigated. The thick RC jacket with a thickness of 500 mm was placed at one side of the thin existing wall with a thickness of 150 mm. At the interface between the wall and RC jacket, a tee-shaped steel section with a number of anchor bolts and dowel bars was used as the shear connector. To investigate the connection performance and strengthening effects, the cyclic loading tests of four jacketed wall specimens were performed. The tests showed that the flexural strength of the jacketed walls under out-of-plane loading was significantly increased. During the initial behavior, the tee shear connector transferred forces successfully at the interface without slip. However, as the cracking, spalling, and crushing of the concrete increased in the exiting walls, the connection performance at the interface was significantly degraded and, consequently, the strength of the jacketed walls was significantly decreased. The flexural strength of the jacketed walls with tee shear connector was estimated considering the full and partial composite actions of the tee shear connector.

Chamaecyparis obtusa is one of the economical conifers planted in Korea due to its good quality timber and wood characteristics. Individuals of C. obtusa containing high terpenes (HT) and low terpenes (LT) were selected for by colorimetric method. The HT of C. obtusa was delayed in wilting against various abiotic stresses compared to the LT plants. The HT group exposed to UV did not significant influence the chlorophyll content, and the chlorophyll value was higher in the HT group than the LT group. Also, chilling treatment (5℃) did not significant influence on the chlorophyll content. However treatment at -4℃ showed relatively low chlorophyll content in the LT group than the HT group. Plants exposure to high temperature was not a difference between the HT and the LT group. However, treatment at 38℃ influenced the chlorophyll content that was increased exposure time-dependently. In salt treatments, chlorophyll in the HT group was lower at high concentrations (300 and 500 mM) of NaCl. However, chlorophyll content increased to slightly in treatment time-dependently, which is 6.7% to 40%. H2O2 treatment has been a negative effect on the chlorophyll content in the HT group. All concentration of H2O2 decreased the chlorophyll content of 5% to 35%. Plants containing high terpenoids were resisted against some abiotic stress such as salt and H2O2. Our results implied that terpenoids could cause various abiotic stress resistance. These results could be utilized for efficient management and biomass production during forest silvicultures.

최근 수상 레저 사업장과 레저기구의 개수는 지속해서 성장하고 있다. 수상레저기구 중에서도 카약과 카누의 보급률이 크게 증가하고 있다. 기존에는 주로 FRP 재료를 사용하여 제작하였으나, 지구온난화, 천연자원 고갈 등의 문제로 인해 청정에너지 및 신재생 에너지에 대한 필요성이 대두됨에 따라 탄소섬유에 대한 수요도 빠르게 증가하고 있다. 본 연구에서는 이러한 사회적인 변화 의식에 부합하기 위하여, 탄소섬유를 적용한 보급형 카약을 설계하고, 제품의 신뢰성을 검증하기 위하여 저항성능 및 구조 안전성 평가를 수행하였 다. 속도 변화에 따른 압력저항과 마찰저항 변화를 검토하였으며, 속도 2.6 m/s 이상에서는 압력저항이 크게 증가하면서 전체저항이 커지 는 현상이 발생한다. 현재 카약 구조는 운용 시 고려할 수 있는 설계하중을 고려 시, 충분한 안전율을 갖고 있음을 확인하였다.

The 20-kHz ultrasonic irradiation was applied to investigate bacterial inactivation and antibiotic susceptibility changes over time. Applied intensities of ultrasound power were varied at 27.7 W and 39.1 W by changing the amplitude 20 to 40 to three bacteria species (Escherichia coli, Enterococcus faecalis, and Staphylococcus aureus). By 15-min irradiation, E. coli, a gram-negative bacterium, showed 1.2- to 1.6-log removals, while the gram-positive bacteria, Enterococcus faecalis and Staphylococcus aureus, showed below 0.5-log removal efficiencies. Antibiotic susceptibility of penicillin-family showed a dramatic increase at E. coli, but for other antibiotic families showed no significant changes in susceptibility. Gram-positive bacteria showed no significant differences in their antibiotic susceptibilities after ultrasound irradiation. Bacterial re-survival and antibiotic susceptibility changes were measured by incubating the ultrasound-irradiated samples. After 24-hour incubation, it was found that all of three bacteria were repropagated to the 2- to 3-log greater than the initial points, and antibiotic inhibition zones were reduced compared to ones of the initial points, meaning that antibiotic resistances were also recovered. Pearson correlations between bacterial inactivation and antibiotic susceptibility showed negative relation for gram-negative bacteria, E. coli., and no significant relations between bacterial re-survival and its inhibition zone. As a preliminary study, further researches are necessary to find practical and effective conditions to achieve bacteria inactivation.

‘Choyoung’, a winter forage triticale cultivar (X Triticosecale Wittmack), was developed at the Department of Rice and Winter Cereal Crop, NICS, RDA in 2015. The cultivar ‘Choyoung’ has the leaves of medium width, long length and green color and a medium grain of brown color. The heading date of the cultivar ‘Choyoung’ was April 30 which was 2 days earlier than that of check cultivar ‘Shinyoung’. Its tolerance or resistance to cold, wet injury, powdery mildew, and leaf rust was similar to those of the check cultivar. But the resistance to the lodging of cultivar ‘Choyoung’ was stronger than that of the check. The average forage fresh and dry matter yield of cultivar ‘Choyoung’ at milk-ripe stages were 40.5 and 15.7 MT ha-1, respectively, which were similar to those (40.3 and 16.1 MT ha-1) of the check cultivar. The silage quality of ‘Choyoung’ was higher than that of the check cultivar ‘Shinyoung’ in crude protein content (5.9%), while was similar to the check cultivar ‘Shinyoung’ in acid detergent fiber (33.9%), neutral detergent fiber (57.3%), and total digestible nutrients (62.2%). It showed a grain yield of 5.59 MT ha-1, which was 38% higher than that of the check cultivar ‘Shinyoung’ (4.05 MT ha-1). This cultivar is recommended for fall sowing forage crops in areas in which average daily minimum mean temperatures in January are higher than -10 ℃.

최근 필로티는 공간의 활용도나 미관상의 이유로 많이 사용되고 있다. 필로티는 외벽보다는 안쪽에 위치하나 외기에 접하는 형태로 강한 바람이 불 때, 바람길이 형성되고 강한 압력을 받아 필로티의 천장 및 벽면 부분의 외장재가 탈락하는 피해가 발생한다. 현재 건축구조기준(KBC-2016)에서는 필로티 건축물에 대한 천장 및 벽면의 풍압계수가 제시되어있지 않아 필로티 부분의 주골조 및 외장재에 대한 구조설계에 어려움이 있다. 이에 본 논문에서는 저층구조물의 관통형 필로티에 대한 풍압실험을 진행하여 풍압계수를 산출하였다. 실험 모형의 변수는 필로티의 높이와 폭으로 두었으며 변수에 따라 풍압계수를 산정하고 풍압분포의 변화를 비교·분석하 였다. 따라서, 필로티의 여러 변수 중 가장 불리한 풍압계수를 제시하여 이를 주골조와 외장재 설계 시 기초자료로 제공하고자 한다.