Immune priming is an increased immunity after prior exposure to a specific pathogen as a kind of adaptive immunity and occurs in insects. However, its underlying mechanism is elusive in insects. Immune priming was detected in a lepidopteran insect, Spodoptera exigua. Prior infection with a heat-killed pathogenic bacterium, Xenorhabdus hominickii, increased survival upon the second infection of the live bacteria compared to larvae without pre-exposure. Plasma collected from larvae with the prior infection significantly up-regulated cellular and humoral immune responses compared to the similar treatment without prior exposure. However, when the active plasma exhibiting immune priming was heat-treated, it lost the priming activity, suggesting a presence of protein factor(s) in the immune priming. Lipocalin is a lipid carrier protein and is well known in vertebrates for diverse physiological functions including immunity. An apolipoprotein D3 (ApoD3) is known to be a lipocalin functioning in immune priming in a mosquito, Anopheles gambiae. A homologous ApoD3 (Se-ApoD3) was identified in S. exigua. Se-ApoD3 was expressed in all developmental stages and larvae, it was highly expressed in hemocytes. RNA interference (RNAi) of Se-ApoD3 expression was performed by injecting its specific dsRNA. The larvae treated with the RNAi were impaired in cellular and humoral immune responses. Furthermore, the plasma collected from RNAi-treated larvae lost the immune priming even at the prior exposure. These suggest that Se-ApoD3 mediates the immune priming in S. exigua.

The walking-stick insects, Ramulus mikado, are outbreaks in several mountainous areas from 2020 to 2022. In recent, some population of the insect are showed rapidly decline in their abundance, while some of them are still maintained high population density. In worldwide, insects belonging to Phasmida are reported to outbreak in their habitats as mentioned above environments, but knowledge about outbreak pattern of the walking-stick insects is still lacking. In this study, we aimed which biological and environmental factors are related to wax and wane of the insect population. From 2022 to 2023, we studied host tree preferences in natural conditions, ecological stoichiometry in major host trees, overwintering ecology of R. mikado eggs, and infection rate by entomophathogenic fungi during growing season.

Coffee has become one of the most popular beverages since the 1960s. These days, coffee is more about pleasure, experience, success, lifestyle, high concentration, and social status. Bhumiratana et al. (2014) state that individuals consume coffee with the intention of eliciting positive high-energy emotions, which can help in reducing fatigue, increasing alertness, improving work performance, and promoting a focused mental state, such as feeling motivated, productive, in-control, or clear-minded. Aguirre (2016) and Bhumiratana et al. (2014) also suggest that people drink coffee to stay awake. As coffee has popularized, café has become important as a place for people meetings. However, customers may tend to evaluate coffee as a service product depending on what service encounter they faced. They might perceive the taste and quality of coffee differently by following their mindset and stereotypes about perfect coffee. Customers pay attention to many factors in consuming coffee depending on service encounters. They may pay less for coffee prepared by robots and evaluate coffee prepared by humans as more precious. Therefore, this study proposes a specific factor theoretical framework of customers’ mindset about coffee prepared by human baristas and robot-barista. The study aims to determine how customers evaluate coffee prepared by baristas and robot-barista. Specifically, to which characteristics they pay attention in barista or robot-barista cases. Then, the study examines relationship between expected and perceived coffee characteristics and intentions to revisit café. Finally, the study compares customers' expectations about coffee depending on contact (barista) or untact (robot-barista) service.

Existing studies report that social media influencers’ number of followers is a determinant of their influence. However, not every consumer follows an influencer with a high number of followers. Therefore, differences in individual characteristics should be considered in the effectiveness of influencer marketing. This study draws on the cultural dimensional theory to examine the moderating role of consumers’ cultural values at the individual level in the effects of social media influencers with many followers. The results show that the relationship between social media influencer follower count and brand reputation depends on the cultural values of individual consumers. This study makes certain contributtions to the advancement of research on influencer marketing and cultural values by identifying the different impact of follower account of social media influencers with many influencers.

목적 : 이 연구의 목적은 지역사회 거주 노인의 자서전적 기억 기능 수준을 측정하고, 자서전적 기억 기능 과 회상기능, 회복탄력성과의 상관관계를 분석하는 것이다. 연구방법 : 60세 이상의 인지적⋅정신적으로 건강한 지역사회 거주 노인을 대상으로 설문조사를 실시했다. 자서전적 기억 기능, 회복탄력성, 회상기능을 측정하기 위해 각각 한국형 자서전적 기억 기능 평가 척도, 한국형 코너-데이비드슨 탄력성 척도, 노인 회상기능 척도를 적용하였다. 변수 간의 상관관계 분석을 위 해 피어슨 상관관계분석과 위계적 회귀분석을 적용하였다. 결과 : 분석 대상자의 평균연령은 73.14세(Standard Deviation; SD = 7.59)였다 (n = 121). 자서전적 기억의 기능적 사용 평균은 1.99점(SD = 0.72) 이었다. 자서전적 기억 기능은 나이가 들어감에 따라 감소하는 경향을 보였다(p = .32). 자서전적 기억 기능과 노인 회상기능은 통계적으로 유의한 정적 상 관관계를 보였다(p < .001). 위계적 회귀분석 결과, 사회인구학적 특성과 건강 특성을 통제하고도 자서 전적 기억 기능은 회복 탄력성과 통계적으로 유의한 정적 상관관계를 보였고(β = 0.229, p < .05), 회 복 탄력성에 대한 자서전적 기억 기능의 설명력은 4.2% 였다. 결론 : 자서전적 기억 기능은 회복탄력성 관련 인자로 확인되었다. 자서전적 기억의 기능적 사용이 노인의 건강 에 미치는 유익에 대한 근거를 강화하기 위해서는 우울집단이나 인지저하집단과 같은 보다 다양한 건강수준의 샘플을 대상으로 자서전적 기억 기능을 측정하고 건강변수와의 관계를 밝히는 추후연구가 필요하다.

본 연구는 대구·경북 우량 산림습원의 관속식물을 확인하고 과거 연구와 비교 분석하고자 2020년 6월부터 2022년 11월까지 현장조사를 수행하였 다. 출현한 관속식물은 119과 427속 741종 64변종 21아종 8품종 1교잡종 등 총 835분류군을 확인하였다. 희귀식물은 총 16분류군(멸종위기종(EN) 1분류군, 취약종(VU) 1분류군, 준위협(NT) 8분류군 및 데이터부족(DD) 6분류군)이다. 특산식물은 총 23분류군이며 습지식물은 172분류군, 신귀화 식물은 47분류군을 확인하였다. 기존 연구(2017년~2018년)에 비해 습지식물의 비율은 23.01%에서 20.60%로 감소하였고, 귀화율은 4.29%에서 5.63%로, 도시화지수는 8.59%에서 14.42%로 증가하였다. 이차건생초지를 구성하는 식물의 비율이 늘어나 습원은 점차 육화가 진행되고 있음을 확인하였다. 이러한 변화 요인은 산림습원으로의 접근성과 수계시스템에 의해 영향을 받는 것으로 판단된다. 토양의 경운, 산림 내 수원의 감소 등으로 육상식물의 유입이 증가하면서 산림습원으로서의 기능이 점차 저하되고 있음을 확인하였다. 그리고 산림습원을 보전하기 위해 보호지역의 지정 등을 통한 방법을 고려할 필요가 있다.

13세기부터 15세기까지 양식적 변화와 이를 설명하는 미술에 대한 문헌들은 공방의 협 업에서 미술가 개인에 대한 관심으로 변화되고 있는 상황을 반영한다. 교회 미술처럼 장소와 미술품이 밀접한 관계를 지닐 때, 공방의 작업과 미술가 개인의 작업은 다르다는 점에서 표 현에 대한 접근 방식도 변화되었다. 이런 점은 공방의 문화를 다루었던 첸니노 첸니니와 미 술의 원리를 다루며 개인의 선택으로서 표현을 다루는 알베르티의 색채에 대한 접근 방식을 통해서 확인할 수 있다. 첸니니는 원색에 흰색을 추가해서 명암을 표현했다면, 알베르티는 검정-원색-흰색을 통해 명암을 표현한다. 장소를 매개로 공간 속에서 미술가의 표현을 조절 해야 하는 공방의 입장은 미술가 개인의 역량을 드러내기 위해 새로운 시도를 진행하고자 하는 입장과 다르기 때문이다. 미술품과 장소의 관계는 15세기 이후 이론이 미술에 대한 담 론을 주도하는 경우에도 새로운 이질적 표현을 살펴볼 수 있다는 점도 확인할 수 있다. 이 시기 교회 미술의 사례를 살펴보는 과정에서 장소와 미술품의 관계는 양식의 변화를 이해하 는 데 중요한 요인이며, 동시에 이론에 바탕을 둔 이론적 관점에서 벗어나는 새로운 시도를 이해하는 데 도움이 된다.

The Derived Concentration Guideline Level (DCGL) using RESRAD code is generally obtained for the reuse of the site and remaining buildings of the decommissioning of nuclear facilities. At this time, the evaluation first considers wide DCGL assuming homogenous contamination for the entire target site. The DCGL derived through this will be compared with the actual contamination measured at the Final Status Survey (FSS) stage to determine whether the site is compliance with criteria. Guidelines for Survey units are presented in MARSSIM and suggested in Class 1 through 3. Therefore, DCGL for the survey unit of a certain smaller area is established by applying a correction factor from wide DCGL, which is define as an Area Factor (AF). Therefore, this study reviewed the AF applied in overseas cases, reviewed the necessary factors for derivation, and compared them by applying factors to the preliminary experimental target area for domestic nuclear installations. The AF is the ratio of the dose from the base-case contaminated area to the dose from a smaller contaminated area with the same radioactive concentration. To this end, an unrestricted resident farmer scenario was applied as the site reuse scenario, which deals with all exposure pathways considered in the RESRAD. The potential exposure pathways considered in resident farmer scenarios are largely divided into external and internal exposures, which are based on NUREG/CR-5512. In addition, in order to calculate the AF, a change in the contaminated area occurs, and accordingly, a variable that varies according to the area, i.e., length parallel to aquifer flow (LCZPAQ), the contaminated fraction of plant food ingested (FPLANT), the contaminated fraction of meat and milk (FMEAT and FMILK), is accompanied. As the contamination area decreases, these variables decrease, and the criteria for reduction were reflected through overseas cases. In this study, three nuclides (C-14, Co-60, and Cs-137) were assumed as representative nuclides, and the area of the contaminated site was selected as 50,000 m2 and reduced at a certain rate. As a result, each nuclide showed different characteristics, but in general, AF increases as the area decreases. Compared to the area of this study, AF values were calculated to be smaller than those of overseas cases, but it was confirmed that the area of the values showed similar patterns. In addition, in the case of C-14, the slope of AF increased rapidly as the area decreased, while Co-60 and Cs-137 showed similar slopes.

With rapid urbanization, the importance of urban warfare is increasing, and it is also required to reflect the characteristics of cities in wargame models. However, in the military's wargame models, the urbanization factor was calculated and used without theoretical basis. In this study, we investigate techniques for estimating the urbanization factor using Fractal dimension theory. The urbanization factor we propose can suggest a logical and valid representative value when used in conjunction with Agent Based Model and other methodologies.

The plant-specific NAC transcription factors control various biological processes, including plant development and stress responses. We have isolated an ANAC032 gene, one of the NAC transcription factor family, which was highly activated by multi-abiotic stresses, including high salt and drought in Arabidopsis. Here, we generated transgenic plants constitutively expressing ANAC032 and its knockout to identify the functional roles of ANAC032 in Arabidopsis under abiotic stress responses. The ANAC032-overexpressing plants showed enhanced tolerance to salinity and drought stresses. The anac032 knockout mutants were observed no significant changes under the high salt and drought conditions. We also monitored the expression of high salt and drought stress-responsive genes in the ANAC032 transgenic plants and anac032 mutant. The ANAC032 overexpression upregulated the expression of stress-responsive genes, RD29A and ERD10, under the stresses. Thus, our data identify that transcription factor ANAC032 plays as an enhancer for salinity and drought tolerance through the upregulation of stress-responsive genes and provides useful genetic traits for generating multi-abiotic stress-tolerant forage crops.

확산강조 자기공명영상은 초급성기 뇌경색 진단과 뇌종양 진단 및 치료에 매우 유용하지만 뇌줄기 주변에 자화 감수성 인공물이 자주 발생하고 있어 이를 최소화하려는 노력이 필요하다. 확산강조영상은 에코평면영상(echo planar image)을 사용하고 서로 다른 자화 감수성을 가진 구조물들이 인접한 경계면에서 영상의 왜곡을 나타낸다. SENSE(sensitivity encoding) 기법은 자화 감수성 인공물을 감소시킬 수 있다. 본 연구는 뇌 줄기의 해부구조를 모방한 팬텀을 만들어서 확산 강조영상 시 자화 감수성 인공물을 감소시키는 최적의 SENSE 인자(factor)를 알아보았다. 산출된 최적의 SENSE 인자와 현재 임상 값으로 만든 영상을 비교 분석하고, 통계적 유의성을 검증하여 유용성을 알아보았다. 팬텀 실험 결과 SENSE 인자의 크기가 증가할수록 자화 감수성 인공물은 감소하였다. SENSE 인자 2.5, 3.0, 3.5, 4.0을 적용한 영상은 기준 영상 과 같은 크기의 왜곡이 발생하였다. 산출된 SENSE 인자 2.5의 실험군과 1.5을 적용한 대조군 각각 40명의 영상을 비교 분석하였다. SENSE 인자 1.5를 적용한 대조군은 SENSE 인자 2.5를 적용한 실험군에 비해서 자화 감수성 인공물이 더 크게 발생하였고, 통계적으로 유의하게 나타났다. 본 연구를 통해서 뇌 확산강조영상 획득 시 SENSE 인자 2.5를 적용한다 면 진단적으로 더욱 가치가 있는 영상을 얻을 수 있을 것으로 사료된다.

우리나라는 삼면이 바다이며 북쪽과 동쪽으로 산지가 위치하고 서쪽으로는 평탄한 지리적 특성을 가진다. 또한 계절풍, 태풍 등의 바람이 지리적 특성으로 인하여 지역마다 풍향별 풍속이 다르다. 그러나 건축구조기준(이하 KDS 41 12 00: 2019)은 전풍향에 대 해 동일한 풍속을 적용한다고 규정하였고, 이것은 상대적으로 약한 풍향에 대해 과다한 풍속을 적용할 수 있다. 이런 점을 고려하여 건 축구조기준(이하 KDS 41 12 00: 2022)에서는 합리적인 설계를 위해 풍향계수를 적용한다. 본 연구는 8개소를 대상으로 10년간의 자 료를 수집하여 사용성 평가를 위한 1년 재현기대풍속과 풍향계수를 산출하였다. 선행 연구된 논문에서 사용성 평가를 위한 1년 재현 기대풍속과 풍향계수를 산출하였으나, 이는 기상청에서 제공하는 일최대풍속으로 산출하였기 때문에 누락되는 풍속이 있을 수 있다고 판단되었다. 따라서 분풍속을 이용하여 모든 풍향의 일최대풍속을 구하였고, Weibull 분포를 통해 재현기대풍속을 산출하였다. 최종적 으로 기상청에서 제공하는 일최대풍속으로 구한 풍향계수와 분풍속으로 구한 일최대풍속의 풍향계수를 비교하여 지역별 풍향계수의 경향 및 두 방법의 차이점에 대해 분석하였다.

In Korea, most nuclear power plants were designed based on the design response spectrum of Regulatory Guide 1.60 of the NRC. However, in the case of earthquakes occurring in the country, the characteristics of seismic motions in Korea and the design response spectrum differed. The seismic motion in Korea had a higher spectral acceleration in the high-frequency range compared to the design response spectrum. The seismic capacity may be reduced when evaluating the seismic performance of the equipment with high-frequency earthquakes compared with what is evaluated by the design response spectrum for the equipment with a high natural frequency. Therefore, EPRI proposed the inelastic energy absorption factor for the equipment anchorage. In this study, the seismic performance of welding anchorage was evaluated by considering domestic seismic characteristics and EPRI's inelastic energy absorption factor. In order to reflect the characteristics of domestic earthquakes, the uniform hazard response spectrum (UHRS) of Uljin was used. Moreover, the seismic performance of the equipment was evaluated with a design response spectrum of R.G.1.60 and a uniform hazard response spectrum (UHRS) as seismic inputs. As a result, it was confirmed that the seismic performance of the weld anchorage could be increased when the inelastic energy absorption factor is used. Also, a comparative analysis was performed on the seismic capacity of the anchorage of equipment by the welding and the extended bolt.

The cellular communication network factor (CCN) family proteins regulate many biological events such as angiogenesis, tumor growth, placentation, implantation, and embryogenesis. The expression and function of CCN1, CCN2, and CCN3 at the maternal-conceptus interface are established in humans and rodents, but little is known about the role of CCN4 to CCN6 in the reproductive organs in any other species. Several studies in transcriptome analysis in pigs have shown that the expression of CCN4 and CCN6 increases in the endometrium during early pregnancy. However, their expression, regulation, and function in the endometrium throughout the estrous cycle and pregnancy have not been fully understood in pigs. Thus, we determined the expression, localization, and regulation of CCN4 and CCN6 during the estrous cycle and at the maternal-conceptus interface in pigs. We found that the levels of CCN4, but not CCN6, changed during the estrous cycle. The levels of CCN4 were greater during mid- to late pregnancy than in the early stage, and the levels of CCN6 were greatest on Day 15 of pregnancy. CCN4 and CCN6 were detected in conceptus tissues during early pregnancy and in chorioallantoic tissues during the later stage of pregnancy. CCN4 mRNA was mainly localized to epithelial cells, CCN6 mRNAs to epithelial and stromal cells in the endometrium. In endometrial explant cultures, CCN4 expression was increased by progesterone, and CCN6 expression by interferon-γ. These results suggest that CCN4 and CCN6 may play roles in the establishment and maintenance of pregnancy by regulating the endometrial epithelial cell functions in pigs.

3D modeling is a technology for representing real objects in a virtual 3D space or modeling and reproducing the physical environment. 2D drawings for viewing the existing building structure have limitations that make it difficult to understand the structure. By implementing this 3D modeling, specific visualization became possible. 3D technology is being applied in a wide range of preevaluation work required for nuclear decommissioning. In Slovakia, 3D modeling was applied to determine the optimal cutting strategy for the primary circuit before dismantling the VVER type Bohunice V1. In Japan, the Decommissioning Engineering Support System (DEXUS) program has been developed that incorporates VRDose, a decommissioning engineering support system based on 3D CAD models. Through this, the cutting length of the work object and the quantity of containers for packaging waste are calculated, exposure dose calculations in various dismantling scenarios, and cost estimation are performed. Korea also used 3D technology to evaluate the decommissioning waste volume for Kori Unit 1 and to evaluate the optimal scenario of the decommissioning process procedure for the research reactor Unit 1. 3D technology is currently being used in various pre-decommissioning evaluations for VVER, PWR, and research reactors. Overseas, a program that matches various decommissioning pre-evaluation tasks with cost estimation has also been developed. However, most 3D technologies are mainly used as a support system for dose evaluation and amount of decommissioning waste calculation. In this study, 3D modeling was performed on the PHWR structure, and physical and radiological information about the structure was provided. The information on the structure can present the unit cost for the work object by confirming the standard of the applied unit cost factor (UCF). The UCF presents the unit cost for repeated decommissioning operations. The decommissioning cost of the work object can be obtained by multiplying the UCF by the number of repetitions of the work. If the results of this study are combined with the process evaluation and waste quantity estimation performed in previous studies, it is judged that it will be helpful in developing an integrated NPP decommissioning program that requires preliminary evaluation of various tasks. In addition, it is judged that a clear cost estimation of the object to be evaluated will be possible by matching the 3D work object with the UCF.

For safeguarding dry storage facilities, a tomography system based on fast and thermal neutron detection was studied in Korea Institute of Nuclear Nonproliferation and Control. The study was conducted laboratory-scale experiments based on a custom built 1/10th scale model cask, He-4 gas scintillation detector array, and multiple 252Cf sources. A filtered back projection (FBP) was utilized to obtain the cask image via MATLAB. The Ram-Lak filter (ramp filter) was employed in FBP for improved the reconstructed image quality. The Ram-Lak filter is the increasing amplitude filter due to the increasing spatial frequency of the image. In spatial frequency, the frequency of brightness change in the low-frequency region is relatively low, and the frequency of brightness change in the highfrequency region is large. Thus, the high-frequency region in the neutron tomographic image is near the neutron sources and the cask, and the low-frequency region is outside of the cask and/or between the source and cask in the study. In order to apply the ramp filter, a Fourier transform is initially performed on projection data, and image reconstruction is performed with the corrected projection data. In this case, the filter is linearly changed. Therefore, a small filter value is applied at lower spatial frequencies to reduce the projection data, and a large filter value is applied at high spatial frequencies to reduce the projection data. The filter scale is a fraction of frequency amplitude, and the filter value applied to the projection data is determined according to the filter scale. This study was conducted for discussion of the image quality due to the effect of the filter scale used for image reconstruction of a neutron tomography system. The results show that in the experiment with one source, the source location was founded when we used the frequency scale of 0.5 and over. In the double or triple source experiment, the source locations and relative activities were found when we used a filter scale of 0.4 to 0.6. When the filter frequency scale of 0.7 to over, the relative activities are hard to know. It can be found that if the filter value is too large or too small, distortion may occur in the reconstruction results. Therefore, it seems reasonable to set a value between 0.4 and 0.6 as the scaling factor for the neutron tomography system. In the future, additional comparative studies will perform validation of the frequency scaling methods.

The risk of various hazardous substances in aquatic environment comprises not only the concentration of substances in the environmental medium but also their accumulation in fish through complex food web and the health risks to humans through the fish. In Korea, the monitoring of residual toxicant in aquatic ecosystems began in 2016 following the enforcement of the Acts on registration and evaluation for the management of chemicals used in daily life (consumer chemical products), and attention has been paid to potentially hazardous substances attributed to them. Recently, studies have been carried out to investigate the distribution of these hazardous substances in the ecosystem and calculate their emission factors. These include the accumulation and transport of substances, such as detergents, dyes, fragrances, cosmetics, and disinfectants, within trophic levels. This study summarizes the results of recently published research on the inflow and distribution of hazardous substances from consumer chemical products to the aquatic environment and presents the scientific implication. Based on studies on aquatic environment monitoring techniques, this study suggests research directions for monitoring the residual concentration and distribution of harmful chemical substances in aquatic ecosystems. In particular, this study introduces the directions for research on trophic position analysis using compound specific isotope analysis and trophic magnification factors, which are needed to fulfill the contemporary requirements of selecting target fish based on the survey of major fish that inhabit domestic waters and assessment of associated health risk. In addition, this study provides suggestions for future biota monitoring and chemical research in Korea.