Schizophyllum commune belongs to Schizophyllum, Schizophyllaceae, Agaricales, Agaricomycetes and Basidiomycotatina. The morphological shape of S. commune was similar with the cap, fan and hair. As for the sensory evaluation, chewness was not good for human's sensory. The major useful component was identified schizophyllan from S. commune extract. Schizophyllan has a great potential for developing medical supplies and functional foods. In our study, we carried out to internal transcribed spacer regions(ITS) for the specimens systematically. Also, we found out the optimal growth conditions of different temperature and media for S. commune cultivation. As the results of these test showed that when we compare with PDA, MCM and ME1 medium, we confirm that optimal temperature is 35℃ in MCM and ME1 medium. And optimal media of growth condition is ME1 and MCM.

The biological activities of the various solvent extracts of mycelial Schizophyllum commune were investigated. The electron donating ability of mycelial S. commune was showcel 39%, 21%, 35% and 43% in Hot-water extract, water extract, ethanol extract and methanol extract at a 1,000 ㎍/㎖ concentration, respectively. As the results of SOD (superoxide dismutase)-like ability of Hot-water extract, water extract, ethanol extract and methanol extract of mycelial S. commune were showed 39%, 21%, 35% and 43% at a 1,000 ㎍/㎖ concentration, respectively. Measurement of ABTS radical cation scavenging activity of all extracts was showed more than 80% scavenging activity at a 1,000 ㎍/㎖ concentration. The tyrosinase inhibition effects related to skin-whitening by mycelial S. commune in Hot-water and water extract at 1,000 ㎍/㎖ were showed closely 5% activity and ethanol and methanol extracts were showed about 10% at 1000 ㎍/㎖ concentration. Antimicrobial activity of Propionibacterium acnes and Malassezia furfur were ineffective in mycelial S. commune extracts. These results showed that the mycelial S. commune has potential for the development of antioxidative, whitening effests and as a natural and functional additives.

감귤은 국내 및 동남아시아 지역에서 많이 즐기는 식품 중 하나이며, 이러한 감귤류의 껍질을 건조시킨 것을 진피라고 한다. 이러한 진피는 한방에서는 이뇨작용, 비장기능을 강화하는 것으로 알려져 있으나, 천연 플라보노이드를 다량 함유하고 있어 학계에서 여러 분야로 연구가 되고 있는 실정이다. 본 연구에서는 플라보노이드 배당체를 함유한 진피 추출물을 β-glucosidase 효소를 이용하여 아글리콘(aglycone)으로 변환할 수 있도록 치마버섯 배양을 실시하였다. 진피 발효 배양액을 HPLC를 이용하여 분석하였으며, UVA에 의한 광손상 보호능을 섬유아세포를 이용하여 측정하였다. 진피 발효 배양액은 COX-2, LOX-5와 같은 항염증 관련 대사에도 관여하여 염증완화에도 도움을 줄 수 있음을 확인하였다. 또한 각질 형성세포를 이용한 interleukin-1α를 측정한 결과 진피발효배양액 처리군의 저해활성이 더 높았다. 이러한 결과로 미루어 볼 때, 진피발효 배양액은 피부에 대한 항염 및 항산화 효과가 우수한 것으로 사료된다.