A 11 year-old, female, shih-tzu mixed-breed dog was presents with history of sudden blindness for 2 days. An ophthalmic test was conducted to find the cause of blindness, including an intraocular pressure test, a fundus test, and an electroretinogram. As a result of the test, the abnormality in the eye could not be confirmed, so MRI request was made. MRI confirmed mass areas with 1.0 × 0.5 mm T2W/FLAIR heterogeneous hyperintense, T1W isointense, and enhancement that spread widely from the dorsal part of the sella turcica to the anterior optical chiasm. Cystic lesion was identified in the front of the lesion, and it had the characteristics of an extra-axial tumor such as a broad base attachment surface and a dural tail signal. Based on these tests diagnosed blindness caused by brain tumors. Clinical symptoms began to improve three days after taking chemotherapy, and all clinical symptoms disappeared after a week. This case report demonstrated that clinical sign, diagnostic imaging and successful treatment result with chemotherapy in canine brain tumor patient.

본 논문에서는 다중 시그마포인트 세트(MSP)를 사용하는 분산점 칼만필터(UKF)인 UKF-MSP를 소개한다. 비선형 동적시스템을 표현하기 위해 널리 알려진 Bouc-Wen 모델을 사용하였고, 비선형성 고려가 가능한 칼만필터 중 UKF를 선정하였다. 그런데 UKF는 두 가지 인공오차와 시그마포인트의 분포를 결정하는 스케일링 파라미터의 값을 튜닝(Tuning)하는 과정을 통해 적절히 설정해야만 대상 동적시스템의 추정하고자 하는 상태(State)를 정확히 추정할 수가 있다. 본 논문에서는 후자의 스케일링 파라미터 설정 문제를 완화하고자 하였으며, MSP를 사용함으로써 기존 UKF에 비해 칼만필터 튜닝 과정에 덜 민감한 UKF-MSP를 제안하였다. 지진으로 인한 급격한 구조손상 시나리오에 대해 UKF-MSP의 안정성을 검증하였다. 제안된 방법은 튜닝과정을 완화함과 동시에 다른 칼만필 터 파라미터인 인공오차에 대해서도 덜 민감한 거동을 보임을 확인하였다.

In this study, using a continuous behavior measurement technique, the short-term behavioral responses and tolerance limits of red seabream Pagrus major fingerlings to sudden exposure to low salinity in a controlled environment were observed. The activity of the fingerlings suddenly exposed to 21.4, 17.3, and 9.8 psu increased temporarily at the initial exposure to show irregular swimming behavior, but then recovered a stable activity pattern through rapid salinity adaptation. However, the organisms suddenly exposed to 7.3 and 4.3 psu could not withstand the salinity stress, and their swimming behavior was severely disturbed and all individuals died within 48 hours. The findings suggest that red seabream underwent a temporary salinity stress process at the beginning of the exposure to concentrations of 10.0 psu or higher. At these concentrations, osmotic control was possible within at least 11 hours, so stable metabolic activity was also possible. However, organisms suddenly exposed to concentrations below 5.0 psu exceeded the tolerance to low salinity and the sublethal limit. In red seabream exposed to this concentration range, severe behavioral and metabolic disturbances were observed, and death was observed due to osmotic control failure. In conclusion, a salinity range of 5.0 to 10.0 psu can be predicted to correspond to a concentration range in which the osmotic control ability of the red seabream fingerlings is lost, and sub-lethal reactions occur.

Naturally occurring left ventricular hyperplasia is a rare but lethal disease. There are very few reports of this cardiac disease in captive nonhuman primates. In a colony of Macaca mulatta (Rhesus monkey) at California National Primate Research Center, a large number of rhesus macaques were diagnosed by autopsy with naturally occurring left ventricular hypertrophy without obvious underlying diseases over a 22-year period. The confirmatory diagnosis of ventricular hypertrophy was based on findings of notable left ventricular concentric hypertrophy with reduced left ventricular lumen, which is very similar to human ventricular hypertrophy cases. This report discusses an 11-year-old Macaca fascicularis monkey (Cynomolgus monkey, crab-eating macaque), weighing 2.95 kg, that was presented for enrollment in a pharmacokinetic (PK) study. During the PK experiment, the monkey died following a sudden decrease in percutaneous oxygen saturation and heart rate. Gross and histological examinations of the heart were performed. On gross pathology, the left ventricular wall was thickened, and the chamber lumen was reduced. In histopathological examination using hematoxylin- eosin and Masson-trichrome stains, fibrosis and myocyte disarray were not observed, but an increased cell density, compared to the normal heart, was confirmed. The autopsy results confirmed left ventricular hyperplasia as the major cause of death.

본 논문에서는 『육조단경』에 나타난 무상(無相)과 무주(無住)의 의미 를 통해 돈오(頓悟)와 무념(無念)의 관계를 이해하고자 하였다. 『육조단경』에서 드러나는 육조 혜능의 선사상은 『열반경』의 불성사상과 『금강경』의 반야사상을 배경으로 하고 있다. 혜능은 일체중생이 본래 구족하고 있는 반야의 지혜와 자성(自性)의 청정한 본성을 깨달아 망상과 미혹에서 벗어나 지혜인(智慧人)이 되도록 설법하고 있다. 이처럼 지혜와 자성을 단박에 깨닫도록 하는 혜능의 주장은 남종선의 근본적인 깨달음의 입장과 일치한다. 남종의 반야사상은 수증의 실천론으로서 무념, 무상, 무주의 선법(禪法)에서 정점으로 드러나고 있다. 혜능은 모든 중생에게 동일한 불성이 존재한다는 초기 선종의 흐름을 따르면서 자성(自 性)과 자심(自心)의 불성 관점을 구체화 시키고 있다. 『육조단경』은 선 사상의 핵심으로 돈오(頓悟)를 제창하면서 수행론인 동시에 궁극적으로 달성해야 할 경지로서 무념, 무상, 무주의 관점을 제시하고 있다. 이와 같이 『육조단경』에서 돈오의 배경으로 제시된 불성론과 반야론 입장에서 무념, 무상, 무주의 관계를 고찰하는 것이 본 논문의 목적이다.

갈색날개매미충은 2010년 8월 국내에서는 처음으로 충남 공주, 예산의 사과와 불루베리를 가해하는 것이 발견되었으며, 미국선녀벌레는 2005년 8월 김해 한림의 단감원에서 처음으로 성충이 발견되어 2008년과 2009년에 김해, 수원 등지에서 확인된 후 최근까지 전국으로 확산되고 있다. 꽃매미는 2004년 천안에서 처음 발견되어 2006년부터 발생이 꾸준히 증가되다 2013년을 정점으로 다소 감소하는 추세를 나타내고 있다. 2018년도 돌발해충들의 국내 발생분포와 현황을 확인하고자 전국 농경지 및 농경지 주변을 대상으로 3월(3.5-3.23)에는 월동난, 7∼8월(7.31-8.10)에는 약·성충 발생을 조사하였다. ‘18년 갈색날개매미충 월동난 조사결과 89개 시군에서 4,628ha로 전년보다 발생지역 7개 시군이 증가 되었으나 발생면적은 8.1% 감소되었으며, 꽃매미는 80개 시군에서 701ha로 발생되어 갈색날개매미충과 유사하게 전년보다 발생지역은 3개 시군이 증가되었으나 발생면적은 10.5% 감소되었다. ‘18년 약·성충 조사에서는 꽃매미는 95개 시군, 1,171ha, 갈색날개매미충은 94개시군, 7,867ha, 미국선녀벌레는 123개시군, 14,779ha에서 발생을 확인하였다. 전체적으로 발생지역은 확대되는 경향이었으며, 발생면적은 전년대비 꽃매미는 1,047ha, 갈색날개매미충은 967ha 감소되었으나 미국선녀벌레는 4,475ha 증가되었다. 특히 미국선녀벌레의 경우 경기와 경남지역에서 급증하는 경향을 나타내었다.

In Korea, there has recently been a hot debate around the theory of sudden enlightenment by Jinul, one of the two greatest scholar monks in the history of the Buddhist tradition of Korea. This debate was provoked by a contemporary monk named "Seongcheol," who criticized Jinul's theory is not perfect due to its emphasis on the need of gradual practice for the ultimate awakening. Since Jinul literally embraces the idea of sudden enlightenment with gradual practice, Seongcheol's criticism has some persuasive power. This debate is important in that it might shed light on the nature of human mind in general in the aspect of its fundamental characteristics. Daosheng, the original proponent of sudden enlightenment in China, emphasizes that the sudden enlightenment of Buddha nature in one's own mind consists in overcoming the objective observation of Buddha nature and perceiving Buddha nature through a spontaneous and subjective self-awakening. Since the ultimate identity of human person in its subjectivity has recently been challenged by some scientists and philosophers, the significance of sudden enlightenment in East Asia, especially in regard with Jinul's theory, might be reexamined in the context of this contemporary challenge so that it can contribute to the deeper discussion on the uniqueness of the nature of human subjectivity.

The magnetosphere is often perturbed by impulsive input such as interplanetary shocks and solar wind discontinuities. We study how these initial perturbations are propagating within the magnetosphere over various latitude regions by adopting a three-dimensional numerical dipole model. We examine the wave propagation on a meridional plane in a time-dependent manner and compare the numerical results with multi-satellite and ground observations. The dipole model is used to represent the plasmasphere and magnetosphere with a realistic Alfven speed profile. It is found that the effects of refraction, which result from magnetic field curvature and inhomogeneous Alfven speed, are' found to become important near the plasmapause. Our results show that, when the disturbances are assumed at the subsolar point of the dayside magnetosphere, the travel time becomes smaller to the polar ionosphere compared to the equatorial ionosphere.

자동차 시뮬레이터에서 운전 형태에 따른 감성을 평가하기 위하여 운전자의 심리생리적 반응을 측정하였다. 운전 형태는 정차, 정속주행(70km/h), 급출발(0km/h→70km/h)및 급제동(70km/h→0km/h)으로 하였다. 피험자는 운전경력이 1년 이상인 20대 남자 12명을 대상으로 Simulator Sickness 및 주관적 쾌적감과 각성감, 뇌파(Electroencep-halogram), 심전도(Electrocardiogram), 피부온도(Skin temperature), 피부전기저항(Galvanic skin response)을 측정하였다. 주관적, 생리적 평가는 각 주행조건에서 주행 전과 후에 실시하였다. 실험결과 정차 및 정속 주행보다 급출발 및 급제동 조건에서 쾌적감과 각성감은 높아졌다. 생리적으로는 정차 및 정속 주행보다 급출발 및 급제동 조건에서 중추신경 반응은 알파파가 감소하였고, 베타파는 증가하였다. 자율신경 반응은 심박율 및 피부전기저항의 증가, 피부온도의 저하로부터 교감신경이 활성화됨을 알 수 있었다. 이러한 결과로부터 운전 형태에 따라 심리 .생리적인 변화가 뚜렷하였고, 시뮬레이터를 이용한 동적 환경에서의 감성 평가가 가능하였다. 감성에 대한 개인간의 차이를 최소화하고 객관화된 감성을 도출하기 위해서는 앞으로 더 많은 대상자에 대한 측정 자료가 요구된다.

We analyze the observations of temperature and ozone measured by the Microwave Limb Sounder (MLS) during the period of 2005–2016, to investigate the vertical structures of temperature and ozone in the stratosphere and mesosphere during stratospheric sudden warming (SSW). We compute the height profiles of the correlation coefficients between 55 height levels of MLS temperature anomalies and compare them with the results of Whole Atmosphere Community Climate Model simulations for three major SSWs. We also construct the temperature and ozone anomalies for the events to investigate the changes in the temperature and ozone distributions with height. There seems to always be a relatively weak but broad negative correlation between the temperature anomaly at 10 hPa and temperature anomalies over the entire mesosphere during the period before SSW events. However, this pattern gets stronger in the lower mesosphere but becomes a positive correlation in the upper mesosphere and lower thermosphere after the onset of SSW. We also found that the temperatures from the simulations show a similar trend to the observational results but with smaller variations and the transition height from negative to positive correlation in the mesosphere is much lower in the simulation than in the actual observations.

Normalized Difference Vegetation Index (NDVI) has played an important role in assessing green plant biomass through remote sensing on global scale since the early 1970s. The concept of NDVI is based on the fact that green plants show higher reflection in near-infrared region than in visible region of the electromagnetic spectrum. However, it is well known that the relocation of chloroplasts in plant leaf cells may dramatically change the optical properties of plant leaves. In this study I traced the changes in the reflectance and transmittance properties of Tobacco leaves at the wavelengths of 660 and 800 nm after a sudden increase in light intensity. The results showed that NDVI of leaves gradually decreased from 72.7% to 69.9% when exposed to a sudden increase in light intensity from 30 to 1,200 μmol/m2 · s. This means that the error resulting from the physiological status of the plant should be accounted for a more precise understanding of ground truth corresponding to the data from the remotely acquired images.

Idiopathic sudden sensorineural hearing loss (ISSNHL) is an emergent disease in otologic field. Audiometric follow-up in patients with ISSNHL is important to assess the benefit of treatment and guide initiation of salvage treatment. However, there have been no report to guide the timing of follow-up. The objective of this study was to compare the recovery duration of patients who diagnosed as ISSNHL in each age group. A total of 150 subjects were included in this study and reviewed the medical and audiological records. According to ages, the subjects were classified into four groups; 0-19, 20-39, 40-59 years old and more than 60 years old. The period of time to final hearing levels was compared based on Siegel’s criteria. The period of time to final hearing levels was significantly different in patients with complete recovery based on Siegel’s criteria. 20-39 group (10.3 days) showed faster recovery than 0-19 (18 days), 40-59 (15 days) and ≥60 groups (23.4 days). The period of time to final hearing levels was not significantly different in patients with partial and slight recovery. Young adults with ISSNHL appear to recover faster than other age groups with ISSNHL. The result suggests that children and the elderly with ISSNHL need longer follow-up for hearing and young adults with refractory ISSNHL need earlier initiation of salvage treatment.

This study investigates the concentration sudden rise in fine particle according to resuspended dust from paved roads after sudden heavy rain in Busan on August 25, 2015. The localized torrential rainfall in Busan area occurred as tropical airmass flow from the south and polar airmass flow from north merged. Orographic effect of Mt. Geumjeong enforced rainfall and it amounted to maximum 80 ㎜/hr at Dongrae and Geumjeong region in Busan. This heavy rain induced flood and landslide in Busan and the nearby areas. The sudden heavy rain moved soil and gravel from mountainous region, which deposited on paved roads and near roadside. These matters on road suspended by an automobile transit, and increased fine particle concentration of air. In addition outdoor fine particle of high concentration flowed in indoor by shoes, cloths and air circulation.