Background: Ameloblastoma are benign but locally invasive neoplasms that represent 10% of all odontogenic tumors. Despite its benign characteristics, ameloblastoma has a high recurrence rate after treatment with a recurrence rate of 55-90%. It is important to identify the risk factors of recurrence to improve patient’s quality of life in oral and maxillofacial surgery. Methods: Patients who underwent surgery at the Department of Oral and Maxillofacial Surgery at Pusan National University Dental Hospital for 5 years from 2017-2021 and were diagnosed with ameloblastoma as a result of postoperative histological examination were included. The patients were divided into two groups, recurrent and non-recurrent, and comparative analysis was performed according to various factors. Results: First, when the lesion was involved with the inferior alveolar nerve (IAN), recurrence was more likely than when it was not. Next, recurrence occurs more often when cortical bone perforation is observed than when it is not. In particular, when resorption is shown on the lingual cortical bone, a remarkable tendency of recurrence is shown. Moreover, in radiographic characteristics, the multicystic type showed a higher recurrence tendency than the unicystic type. Conclusion: When the lesion is multicystic, perforating the cortical bone, infiltrating the adjacent soft tissue, or involving the IAN, a high recurrence rate is shown. The results of this retrospective analysis of the recurrence trend of ameloblastoma over a 5 years period are to contribute significantly to insight and reduction of recurrence rates in treatment for polymorphic lesion in oral and maxillofacial area.

목적 : 본 연구는 산재 수부손상환자들을 대상으로 수부재활치료를 시작하는 시기가 손 기능에 미치는 영향을 알아보고자 하였다. 연구방법 : 본 연구는 후향적 코호트 연구(retrospective cohort study)로 전자의무기록(electronic medical record)을 활용하였다. 2018년 1월부터 2019년 12월까지 경남 창원의 C 병원과 전남 순천의 S 병원에서 수부재활치료를 받은 환자 127명을 대상으로 치료시기에 따른 손 기능 차이를 알아보기 위해 손상 후 4개월 이전(61명)과 4개월 이상(66명) 두 그룹으로 나누어 장악력, 집기, 휴식 시 통증, 활동 시 통증, Jebsen- Taylor Hand Function Test(JTHFT), Quick DASH를 비교하였다. 결과 : 산재 수부손상환자에게 수부재활치료를 제공하였을 때 두 그룹 모두 손 기능이 유의하게 향상이 되었다(p < .05). 그룹 간 손 기능 변화량 비교에서는 장악력 검사, 측면집기, 휴식 시 통증, 활동 시 통 증, Quick DASH에서 4개월 이전 그룹이 4개월 이상 그룹보다 통계적으로 유의한 향상이 있었다(p < .05). 결론 : 본 연구 결과를 통해 치료시기가 빠를수록 손 기능 향상에 긍정적인 영향을 미치는 것을 알 수 있 었다. 따라서 수술 이후 산재수부손상 환자에게 초기재활에 대한 정보제공과 진단명, 손상부위, 손상정도에 따른 적절한 치료가 필요함을 제시하였다.

The vascular origin diseases occurring in the oral and maxillofacial region can be divided into hemangiomas and vascular malformation. They are rare and early lesions are not easy to diagnosis, so they may be misdiagnosed as clinicians, or the method and timing of treatment may be inappropriate. For 10 years, from August 2005 to August 2015, we analyzed the clinical records, diagnosis, treatment, and prognosis of 23 patients with hemangioma or vascular malformation confirmed by clinical, histopathological or radiological examination of maxillofacial lesions at department of oral and maxillofacial surgery, Pusan National University Hospital and Pusan National University Dental Hospital. Chief complants of patients were mainly swelling, mass, and spot-like lesion on various intraoral sites. Treatments were performed with excision, embolization, sclerotherapy, depending on each lesions condition. Arteriovenous malformation cases were more frequently recurred than other lesions. Prognosis of lesions were relatively good but close observation should be needed.

Echocardiography is one of the most useful diagnostic techniques for differentiating heart disease as well as mitral valve lesion. Forty client-owned small breed dogs (weight, 2.3−13.2 kg) aged between 8−17 years with myxomatous mitral valve degeneration (MMVD) were included in the present study. The diagnosis of MMVD in dogs was made based on the clinical signs, chest radiography data, and echocardiographic findings. Echocardiographic examinations were conducted in accordance with recommended standards for dogs. M-mode, Doppler, and 2D echocardiography were performed in left and right lateral recumbency. 2D echocardiography was used to measure LA and Ao diameter from 2D short axis at the level of the aortic valve. In the comparison of conventional echocardiography indices in dogs with different stages of heart failure with MMVD, significant differences were observed in E/A ratio (p=0.005), EDV (p<0.001), EDVI (p<0.001), E-peak velocity (p= 0.001), ESV (p=0.028), ESVI (p=0.004), LA (p<0.001), LA/Ao Ratio (p<0.001), LVIDd (p<0.001), LVIDd/Ao Ratio (p<0.001), LVIDs (p=0.036), LVIDs/Ao Ratio (p=0.002), and MR Velocity (p=0.026). In addition, distinct correlations were found in EDV (r=0.712), LA/Ao ration (r=0.830), LVIDd (r=0.724), and LVIDd/Ao ratio (r=0.759). This study found that known conventional echocardiographic indices, including EDV, LA/Ao ratio, LVIDd dimension, and LVIDd/Ao ratio correlated with the severity of MMVD in point of significant differences and distinct correlations.

본 연구는 췌장암 환자가 수술 후 보조 요법으로서 항암화학요법 또는 항암-방사선병용요법을 시행받는 경우에 있어서 치료 성적의 차이가 있는지 조사하기 위해 시행하였다. 2008년에서 2012년까지 부산대학교병원에서 수술을 시행한 40명의 췌장 선암 환자들의 의무기록을 조사하였다. 근치적 목적으로 수술을 받은 환자 중 29명이 항암화학 요법 또는 항암-방사 선병용요법의 보조요법을 시행받았다. 보조요법의 시행 (p =0.025)과 완전 절제(p =0.043)가 더 긴 전체 생존기간과 연관이 있었다. 보조요법으로서 항암화학요법을 시행한 군과 항암-방사선병용요법을 시행한 군에서 전체 생존 기간은 유의하게 다르지 않았으나 보조요법을 하지 않은 군과 비교하였을 때에는 보조요법으로 항암화학요법을 시행한 군에서 유의하게 높은 전체 생존율을 보였다. 수술 후 보조요법은 췌장 선암 환자의 예후를 향상시키며, 항암화학요법이 항암-방사선 병용요법보다 양호한 결과를 보인다.

배경/목적: 2012년 급성췌장염의 애틀랜타 분류 개정안이 발표되었고 이후 널리 이용하고 있다. 본 연구는 1992년 애틀랜타 분류와 2012년 개정안을 이용하여 급성췌장염 환자를 분류한 후 임상경과를 비교하였다. 방법: 2012년 1월부터 2013년 7월 사이 대구경북지역 6개 대형 병원에 입원한 총 574명의 급성췌장염 환자를 대상으 로 후향적 연구를 시행하였다. 1992년 애틀랜타 분류와 2012 년 개정안을 이용하여 중등도 평가를 시행하고 인구 통계 자료, 장기부전, 국소합병증, 입원기간, 임상경과 등을 분석하였다.결과: 대상 중 377명(65.7%)이 남성이었다. 연령의 중간값 은 55.4세였다. 급성췌장염의 2대 원인은 음주(238명, 41.5%)와 담석(193명, 33.6%)이었다. 2012년 개정안에 따르 면 경증췌장염은 356명(62%), 중등췌장염은 197명(34.3%), 중증췌장염은 21명(3.7%)이었다. 입원기간은 중증도 증가에 따라 통계학적으로 유의하여 증가하였다(경증 5.9일, 중 등 8.3일, 중증 13일, p <0.001). 모든 경증 및 중등췌장염 환자는 임상적으로 호전되었다. 하지만, 호전을 보이지 않은 11명은 모두 중증췌장염에 속했다. 결론: 애틀랜타 분류 개정안이 급성췌장염의 임상경과를 예측하는 데 있어 좋은 방법이다.

Allergic disorders are exaggerated immune responses to foreign antigens, regardless of the mechanism, while atopic disorders are exaggerated IgE-mediated immune responses (type I hypersensitivity). Allergic dermatitis is a common pathological condition of skin in humans and dogs. Canine allergic dermatitis presents with clinical signs similar to those reported in humans, and its causes are complex; therefore, diagnostic tests and treatments may need to be adjusted for each patient. Dogs with allergic dermatitis can suffer from secondary infections, which must be considered and confirmed or excluded for successful treatment. In this report, 35 cases of canine allergic dermatitis diagnosed using variable methods, including histological and cytological examination, are described. Patients were treated with oral or topical medications (antimicrobials, anti-inflammatories, immune modulators, topical ointments, and medicated shampoos), and their diets and environmental surroundings were also modified. This report provides an analysis of the breed, gender, age of onset, clinical signs, diagnostic methods, and treatments for canine allergic dermatitis. The information on canine allergic dermatitis presented here could be helpful in the study of human cases because these two species often share living spaces, environments, and lifestyles more closely than other animals. However, previous reports have suggested that human and canine allergies differ in some features, such as involvement of histamine in induction of pruritus, and in histopathological characteristics such as cutaneous structures.

Retrospective study on the comparison of outbreaks of food poisoning for food hygiene in Korea and Japan. The average value of morbidity rate by year in Korea during the period of 1971 to 1992 was 2.9 per 100,000 population, and that of Japan was 29.1. The mean value of mortality rates in case of food poisoning by year in Korea was 2.33%, and that of Japan was 0.07%. When compared the rates of morbidity and mortality between Korea and Japan during the same period, the morbidity rates of Japan were much higher than those of Korea (p$lt;0.0l). However, mortality rate of patients in Korea were much higher then those of Japan (p$lt;0.01). Resulting from comparative observation of food poisoning by preparing facilities between Korea and Japan. The highest list the places where the outbreaks occurred was home-made foods accounted for 48.8% of the total cases in Korea and that of Japan was restaurants accounted for 33.0%. Causative foods in Korea, the most common incrimination vehicles were seafood, meat and animal products and grain and vegetables, including mushroom. However, in the case of the common incrimination vehicles Japan were unknown and other foods, seafood, vegetables and meat and animal products etc.. Food poisoning of pathogenic substance in Korea were 60.9% of bacterial food poisoning of the total cases showing that Vibrio species, Salmonella spp., Staphylococcus app., pathogenic E. coli, Clostridium app. and other app. were 33.3%, 26.2%, 16.3%, 5.3%, 0.4% and 18.5%, respectively. On the other hand, in Japan, major causes were Vibrio app. (45.7%), Staphylococcus app. (23.7%), Salmonella app. (16.8%), pathogenic E. coli (3.8%), Clostridium app. (0.2%) and other app. (9.6%).

성인 남성들이 2002년부터 2006년 까지 건강검진을 받기위해 대학병원을 내원한 성인 남성 80명을 개인별 골밀도 를 5년간 관찰하여 분석하였다. 연구 대상자 성인 남성 80명의 평균연령은 43.15 ± 4.82세였다. 대퇴경부의 골밀도는 1차 측정에서 -0.61에 비하여 4차 및 5차 측정에서 유의하게 감소하였으며, 척추 골밀도는 1차 측정 -0.67에서 2차 측정에서 유의한 감소를 나타냈지만 3∼5차 측정에서 유의한 차이를 보이지 않았다. 생활습관에 따른 음주, 흡연, 운 동, 식습관에 따른 군 간의 대퇴경부 및 척추 골밀도 변화 값의 차이는 보이지 않았다. 1차 측정에서의 대퇴경부 골밀 도를 기준으로 골밀도 상(0 ≦ BMD ), 중(-1.0 ≦ BMD <0), 하(BMD < -1.0) 집단에서 1차 측정과 5차 측정 골밀 도의 차이를 비교하였을 때, 상 집단에서 대퇴경부 골밀도가 1차 0.67 ± 0.76에서 0.42 ± 0.93로 유의하게 감소하였 다. 다른 집단에서는 전후 비교에서 유의한 차이를 보이지 않았다. 대상자들의 나이에 관계없이 젊어서부터 골밀도가 낮은 사람들은 대퇴경부 및 척추의 골밀도가 낮아 있었으며, 골밀도가 높은 사람들은 1차 측정 때부터 5차 측정 때까 지 높았다. 대퇴경의 골밀도는 1차 측정에 비해 5차에서 유의한 감소를 나타내어 척추보다는 대퇴경부의 골밀도에 주 의하도록 한다.