Recently, extreme terrorist attacks have frequently occurred around the world and are threatening the international community. It is no longer a safe zone for terrorism in our country. Therefore, domestic nuclear facilities as the highest level of national security facilities have established a physical protection system to protect facilities and lives against terrorist attacks. In addition, security search and access control are conducted for controlled items and unauthorized person. However, with the development of science and technology, disguised weapons or homemade explosives used in terrorism are becoming very sophisticated. Therefore, nuclear facilities need to strengthen security search of weapons or homemade explosives. Since these disguised weapons or homemade explosives are difficult to find only through security search, it is also necessary to actively identify unspecified people who possess disguised weapons or do abnormal behavior. For this reason, the “Abnormal Behavior Detection Method”, which is very effective in preemptive response to potential terrorist risks, has been introduced and operated in aviation security field. Korea Institute of Nuclear Nonproliferation and Control (KINAC) has established a “Practice Environment for Identifying Disguised Weapons” in 2020 for trainees to recognize the dangers of controlled items and to use for physical protection education. This Practice environment has not only the basic explanation of the controlled items of nuclear facilities, but also various actual disguised weapons were displayed. It also introduces actual terrorist incidents using homemade explosives such as attempted bombing of a cargo plane bound for Chicago and the Boston Marathon bombing. And then a model of the disguised explosives actually used is displayed and used for education. In addition, in 2022, the “Abnormal behavior detection method” education module was developed and used for physical protection education. In this module, the outline and introduction of the “Abnormal Behavior Detection Method” and “Behavior Detection Officer (BDOs)” are explained. In this way, the access control and security search system of nuclear facilities require the overall monitoring system, not only for dangerous goods but also for identification of persons possess and carrying them. This study describes the development of the Curriculum for “Disguised Weapon Identification” and “Abnormal Behavior Detection Method” to enhance the effectiveness of physical protection education.

Mecoprop-p, a chlorophenoxy herbicide, has been widely used since the 1980s. Due to its high water solubility, it could be detected in the aquatic environment, as it has already been detected in the surface water or groundwater in several countries. The toxicity of other chlorophenoxy herbicides has been reported; however, there are few studies on the toxicity of mecoprop-p, one of the chlorophenoxy herbicides, on aquatic organisms. Here, we investigated the toxic effects of mecoprop-p using zebrafish. After mecoprop-p exposure, we observed that the zebrafish larvae eyes did not form normally, heart edema was generated, and the body length was shortened. The number of cells undergoing apoptosis also increased in the anterior part including head, heart, and yolk sac of the mecoprop-p-treated zebrafish compared to the untreated controls. Moreover, cardiovascular structures, including the heart and aortic arches, were also malformed after exposure to mecoprop-p. Therefore, our results suggest that mecoprop-p could cause abnormal development in zebrafish larvae and there is also a high possibility that mecoprop-p would be toxic to other aquatic organisms.

Purpose: This study aimed to develop a web-based video program related to abnormal mental disorder behaviors in standardized patients and verify its effectiveness for nursing students. Methods: This study consisted of pre-test and post-test for a non-equivalent control group design. The participants were 46 nursing students(experimental group: 23, control group: 23). The experimental group was trained in a video program that applied standardized patients, while the control group received traditional training. Data collected from March to June, 2020, were analyzed using IBM SPSS Statistics for Windows, version 25.0, chi-square test, Fisher's exact test, Mann-Whitney U test, and independent t-test. Results: The difference between the experimental and control groups was statistically significant in terms of learning satisfaction (Z=2.08, p=.038), learning self-efficacy(t=2.80, p=.009), motivation for transfer(t=3.45, p=.001), and clinical reasoning competence(t=2.28, p=.028). Conclusion: This study showed that a video program on abnormal mental disorder behaviors in standardized patients is an effective tool for mental health nursing education.

Ionizing irradiation can be used as an alternative to chemical fumigants for disinfestation of cut flowers, agricultural products, seeds, foods, medical products, and spices. In this study, we investigated the effect of electron beam irradiation on reproduction and development in Spodoptera litura. When irradiated to the adults, there was no difference in fecundity. However, egg hatching was considerably decreased. When irradiated to the pupae, fecundity was decreased as dose increased and wing deformity of newly emerged adults was increased as time passed. When irradiated to the larvae, developmental period and pupa deformity was significantly increased. In order to investigate the molecular mechanism of sterility and abnormal development, we performed quantitative real-time PCR and SDS-PAGE.

The effects of X-ray irradiation on development and reproduction of Spodoptera litura were examined. Eggs, larvae, pupae, and adults were irradiated at target doses of 10 - 250 Gy. When eggs were irradiated with 30 Gy, egg hatching was completely inhibited. When irradiated to the larvae, pupation was inhibited at 100 Gy and larval period was delayed. When irradiated to the pupae, emergence was inhibited at over 100 Gy. When irradiated to the adults, longevity and fecundity did not show any differences. However, egg hatching was significantly decreased at 70 Gy and above. Also, X-ray irradiation was not induced the rapid death of S. litura. Reciprocal crosses between irradiated and unirradiated moths demonstrated that males were more radiotolerant than females. The levels of DNA damage in S. litura adults were evaluated using the alkaline comet assay. Our results indicate that X-ray irradiation increased levels of DNA damage. The recovery of DNA damage in S. litura adults increased as time passed. But DNA damage hasn't recovered fully. These results indicate that X-ray irradiation induced abnormal development and reproduction by DNA damage in S. litura.

The American serpentine leafminer fly, Liriomyza trifolii (Burgess), is one of the most destructive polyphagous pests world wide. In this study, we determined electron beam doses for inhibition of normal development of the L. trifolii and investigated the effect of electron beam irradiation on DNA damage and p53 stability. Eggs, larvae, pupae and adults were irradiated with increasing doses of electron beam irradiation (six levels ranges from 30 to 200 Gy). At 150 Gy, the number of adults that developed from irradiated eggs, larvae and pupae was lower than those of untreated control. Fecundity and egg hatchability decreased depending on the doses applied. Reciprocal crosses between irradiated and unirradiated flies demonstrated that males were more radiotolerant than females. Adult longevity was not affected in all stages. The levels of DNA damage in L. trifolii adults were evaluated using the alkaline comet assay. Our results indicate that electron beam irradiation increased levels of DNA damage in a dose-dependent manner. Moreover, low doses of electron beam irradiation led to the rapid appearance of p53 protein with in 6 h; however, it decreased after exposure to high doses (150 Gy and 200 Gy). These results suggest that electron beam irradiation induced not only abnormal development and reproduction but also p53 stability caused by DNA damage in L. trifolii. We conclude that a minimum dose of 150 Gy should be sufficient for sterilization of L. trifolii.

Recently, buildings tend to be large size, complex shape and functional. As the size of buildings is becoming massive, the need for structural health monitoring (SHM) technique is increasing. Various SHM techniques have been studied for buildings which have different dynamic characteristics and influenced by various external loads. “Abnormal behavior point” is a moment when the structure starts vibrating abnormally and this can be detected by comparing between before and after abnormal behavior point. In other words, anomalous behavior is a sign of damage on structures and estimating the abnormal behavior point can be directly related to the safety of structure. Abnormal behavior causes damage on structures and this leads to enormous economic damage as well as damage for humans. This study proposes an estimating technique to find abnormal behavior point using Hilber-Huang Transform which is a time-frequency signal analysis technique and the proposed algorithm has been examined through laboratory tests with a bridge model using a shaking table.

In the present study, to understand the process of abnormal pigmentation (hypermelanosis) on the blind side of olive flounder P. olivaceus during early development, we investigated an time that staining on the blind side is initially observed with the naked eyes, counted the number of stained spot on the blind, and calculated the ratio of area stained on the blind side, and the ratio of fish pigmented on the blind side with growth. The present experiment was initiated at 24-day after hatching (dah), just after the starting of metamorphosis, in which fish mean size is total length (TL) 12.4±0.2 ㎜ and body weight (BW) 19.9±0.7 ㎎, and was finalized at 94-dah (TL 72.0±0.6 ㎜, BW 3,912.3±119.4 ㎎). The experimental animals were reared in FRP tank at 20±0.5℃ in water temperature and 30.9±0.1 psu. The experimental animals were feed with rotifer, Artemia nauplii and commercial food according growth stage. As results, the pigmented spots are composed with adult-type melanophores. The first spot was found in microscopy level at 38-dah (TL 18.3±0.4 ㎜, BW 57.6±4.1 ㎎), but the first staining spot observed with the naked eye was found 52-dah (TL 37.6±0.5 ㎜, BW 534.2±30.9 ㎎) around the pectoral fin and the caudal peduncle. The pigmented spots became more distinctive and expanded around the edge of rear on the blind side. The number of spots and the ratio of area stained on the blind side sharply increased between 31-dah and 80-dah, and between 66-dah and 94-dah, respectively. The ratio of fishes stained on the blind side increased between 45-dah and 73-dah, and then was stagnated to 94-dah. Therefore, these results concluded that the pigmentation on the blind side of olive flounder is not an temporary and reversible color change but an irreversible abnormal phenomenon that pigment cells is continuously differentiated on the blind side with growth for early development just after metamorphosis in artificial culture conditions.