이 연구는 중학생의 과학에 대한 흥미를 높이고 탐구 능력을 향상시킬 수 있는 지구과학 모듈의 개발을 목적으로 수행되었다. 모듈은 학생들이 구체적인 상황을 통해 탐구 과정 기능을 학습할 수 있는 탐구 기능 중심 모듈로 개발하였다. 하나의 모듈은 여러 개의 활동으로 구성되며, 각 활동들은 목표한 탐구 과정 기능에 초점을 맞추어 개발되었고, 활동의 수행을 통해 학습의 효과가 극대화 되도록 하였다. 현장 교사 웍샵과 두 차례의 현장 적용을 통하여 개발된 모듈의 효율성을 평가하였다. 교사들은 모듈의 활동들이 학생들의 흥미를 높이는 데 도움이 되며, 모듈의 활동을 통해 학생들의 탐구 기능이 향상될 것이라고 평가하였다. 학생들은 모듈의 활동들이 재미있으며, 자신들이 직접 활동하고 체험할 수 있는 점이 좋았다고 응답하였다. 모듈을 이용한 수업은 학생 중심으로 이루어졌으며, 교사는 모듈 활동의 결과물을 통해 학생의 성취 수준을 쉽게 진단하고 적절한 피드백을 제공해 주는 것이 가능하다. 따라서 이 연구에서 개발된 모듈의 학습을 통해 학생들의 탐구 능력이 향상될 것으로 기대된다.

Cyclooxygenase- 2 (COX-2) is an inducible enzyme that is not found in normal conditions,. but is induced by a varie ty of pathophysiologic conditions of tissues by growth factors. inflammatory stimuli. oncogenes and tumor promoters, COX-2 is upregulated in a number of epithelial cancers. including in oral premalignant and malignant lesions, The mode of action of COX-2 in carcinogenesis may include mutiple mechanisms that may be acting at different stages of malignant disease, In this study. the expression of COX- 2 protein was assessed quantitatively 없d qualitatively by immunohistochemistry during DMBA-induced hamster buccal pouch carcinogenesis, The immunoreactivity for COX-2 protein increased as the tissue passed from hyperplasia to dysplasia and SCC, The highest mean expression was SCC at 14 week, The differences between COX-2 expression in the normal and that the dysplastic and carcinomatous lesions was statistically significant, In addition. the mean values of COX -2 expression in the stromal cells increased gradually during malignant progression, The results suggest that increased COX-2 expression may be associated with the chemically induced carcinogenic progression of hamster buccal pouch model, The gradual increasing COX-2 expression de tected during the progressive manner toward more malignant lesions shows that the COX-2 protein can have an important role in both the early and the later stages of multistep oral carcinogenesis

This study is to examine the Severe-Ornament (Vyuha :Sanskrit) of wooden pagodas in Shilla period in order to assume a detailed shape of wooden pagodas called the palace style, the multi-story style, the towered namsion style, that were built at the temples in Gyeongju during Shilla period. The Severe-Ornament had been used traditionally by installing a Buddhist image, Guardians, Sarira and by printing a color. The other hand, The roof tiles and tiles were annexed to the Severe-Ornament so as to enhance the value of the wooden pagodas. The Vyuha had been used not only to install a highly valued Buddhist image in the wooden pagodas but also to represent an important part of ritual art of Silla period. Therefore, it was possible to find out a variety of details of the wooden pagodas in Shilla period.

Slotted ALOHA(S-ALOHA) is widely used in local wireless network. We analyze the performance of contention-based model in wireless LAN using S-ALOHA protocol. We analyze the performance of binary exponential backoff (BEB) algorithm under the slotted ALOHA

To deterrnine the effects of insulin-like growth factor system in the aging process of the rat submandibular gland, expression pattems of 19f-1, 19f-2 and 19f-1 receptor were investigated by immunohistochem엽따. 1n addition, age-related changes of 19f-1 and 19f-2 concentrations in serum were deterrnined by radioimmunoassay 19f-1, 19f-2 and 19f-1 receptor were principally expressed 띠 the duct cells. 19f-1 receptors were strongly expre잃ed in 2-week-old group but were gradually decreased with advancing age. 19f-1 expressions were the strongest in the excretory and striated ducts of 7-month-old and 17-month-old groups. 19f-1 expressions, however, were weakiy expressed in the cells of granular convoluted tubules of 7-month잉ld ， 17-month-old and 27-month-old groups. 19f-2 expressions were found in some cells around duαs of 2-week-old group but were persisted relatively weak. The concentrations of 19f-1 and 1향2 in serum were the highest in 2-week-old group but were decreased and maintained at low level with advancing age. These results show that all components of 19f system were expressed in the rat submandibular giand in an age-related manner. Serum concentrations of all components of 19f system were not dosely related with the intra-밍and비ar expresslon patterns 까lerefore ， 1양 systerns may play important roles in the aging process of the rat submandibular gland in an autocrine/paracrine manner

Amino acid transporters play an important role in supplying organic nutrient to cells. The expression of L-type arnino acid transporter 1 (LATl) and its subunit 4F2 heavy chain (4F2hc) was evaluated to deterrnine the alterations to these transporters in oral norrnal mucosa (ONM) , oral precancerous lesion (OPL) and oral squamous cell carcinoma (OSCC). Sections from formalin-ftxed, paraffm-embedded S따nples of ONM, OPL or OSCC were exarnined using immunohistochernical staining to detect LATl and 4F2hc proteins. 까le LATl and 4F강lC expression increased progressively from ONM to hypeφ，Iastic and to dysplastic lesions and OSCC. In partiαlar， LATl rnay be a more S야dftc indicator of tumor prog~않sion than 4F2hc. 까le gradually increasing LA Tl and 4F2hc expression detected during the multistep progressive change shows that the protein rnay have an important role in the early stages of multistep oral carcinogenesis. In addition, the specific inhibition of LA Tl and 4F2hc rnight be a new rationale to suppress oral cancer progression.

본 연구는 장기간의 이용과 간섭으로 훼손된 선흘곶 방목초지를 원식생인 상록활엽수림으로 복원하기 위하여 식생유형에 따른 식물군집구조 분석을 통해 천이경향을 예측하고 적합한 복원방안을 도출하고자 하였다. 총 26개 조사지를 선정하여 분석한 결과 우점종의 평균상대우점치에 따라 4개 유형으로 구분되었고 교목층 우점종의 경급을 고려하여 6개 군집으로 분류하였으며 군집 I은 덩굴성관목림, 군집 II는 상록활엽수 관목림, 군집 III은 소경목의 상록활엽수림, 군집 IV, V는 중경목의 상록활엽수림, 군집 Ⅵ은 대경목의 상록활엽수림이었다. 관목림의 출현종은 각각 24, 28종이었고 소경목 상록활엽수림은 16종, 중경목 상록활엽수림은 29, 30종이었으며 대경목 상록활엽수림은 27종이었다. 전체 종다양도지수는 0.8763∼1.2630이었으며 중경목과 대경목 상록활엽수림간 유사도지수가 높게 나타났다. 군집 I, II, III은 방목초지에서 상록활엽수로 천이가 진행된 유형이었고 군집 IV, V, Ⅵ은 방목지내 잔존림으로서 난대 상록확엽수림과 식생구조가 유사하였다. 선흘곶 방목초지지역을 상록활엽수림으로 복원하기 위해 구실잣밤나무, 종가시나무군집을 목표로 하여 선흘곶 내 상록활엽수림을 모델림으로 제시하였으며 복원모델군집의 생육밀도는 교목층에 구실잣밤나무, 종가시나무가 100m2당 10주, 아교목층에는 동백나무, 사스레피나무, 종가시나무가 100m2당 14주이었다.

본 연구에서는 clonal cell lines을 효율적으로 확립할 수 있는 방법을 제시하기 위하여 배양액 내에 catalase와 ME 첨가가 clonal cell line 확립 효율에 미치는 영향을 검토하였다. 임신 50일령의 암퇘지에서 얻은 태아섬유아세포를 2회 passage한 후 동결 보관하였다가 실험에 이용하였다. 단일세포를 catalase나 ME가 첨가된 배양액이 들어 있는 96-well dish로 옮겨 배양하였다. 단층이 형성된 세포는 4-we

Kim, Jung-woo. 2004. The Changes of Language Usage in Radio Advertisements. The Sociolinguistic Journal of Korea, 12(2). The purpose of this study is to examine the changing trends of language usage in radio advertisements. Radio has made efforts to compete with other mass media. This study proposes to divide the changing trends of radio advertisements into five periods according to competing relationships between radio and the other media. Diverse aspects of language usage were found in each period; they relate to the radio's efforts to solidify its position against other competing media such as newspaper and television. This paper suggests, in conclusion, that the trends of language usage in radio advertisements have reflected the radio's efforts to fortify its communication efficiency in communicating to the masses.

본 연구는 중 ·고등학교 과학 교사를 대상으로 탐구 학습에 관한 인식을 조사하고 교사 수준의 탐구 학습 실태를 조사하기 위한 것이다. 탐구 학습 인식에 관한 설문지를 개발하여 서울교육과학연구원의 실험 연수에 참여한 서울지역 중 · 고등학교 과학 교사를 대상으로 조사한 결과에 의하면, 교사들은 과학 교육의 중요한 목표가 과학에 대한 흥미를 높이는 것이라고 생각하고 있으며, 실생활과 관련된 소재를 수업에 활용하는 것으로 조사되었다. 대부분의 교사가 탐구 학습을 학습자 중심의 열린 탐구 학습에 대한 인식하고 있었고, 대학 입시 제도, 탐구수업 보조 자료의 부족, 학생들의 의지 부족, 교사들의 탐구 학습에 대한 인식의 부족 등이 탐구 학습의 실현을 저해하는 요인으로 조사되었다.

The purpose of this study was to determine the most effective method of forming cooperative small groups for middle school English classes using ICT. To achieve this goal, the two experimental classes composed of 73 middle school 2nd graders were taught in a task-based teaching-learning model using ICT for 12 weeks. Throughout the 12-week period, two types of grouping models were applied to the students: Experimental class A consisted of differentiated heterogeneous group based on the regular English examination marks, and experimental class B was made up of a differentiated heterogeneous group based on the ICT skill standard for student (ISSS). The study discovered the small group based on the ISSS showed significantly different statistical results in the cognitive, affective and information-using skills. The ISSS could be used as an additional criterion in forming small groups for middle school English classes. In fact, the study shows that it creates better results than the traditional grouping based on learners' English grades if the lessons are given in using ICT.